Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats

Journal of Ethnopharmacology

Volumn 172, Issue , 2015, Pages 238-246

  Fang, Hua ^a   Hu, Xiaohong ^a   Wang, Meiling ^a   Wan, Wencheng ^a   Yang, Qiaohong ^a   Sun, Xiaosheng ^a   Gu, Qiong ^b   Gao, Xinxin ^a   Wang, Zhengtao ^c   Gu, Lianquan ^b   Oliver Chen, C Y ^d   Wei, Xiaoyong ^a,d  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d TUFTS UNIVERSITY   (United States)

Author keywords

Aldose reductase (AR); Cataract; Dendrobii; Gigantol; Inducible nitric oxide synthase (iNOS); Mechanisms

Indexed keywords

ALDEHYDE REDUCTASE; ANTIOXIDANT; GALACTOSE; GIGANTOL; HISTIDINE; INDUCIBLE NITRIC OXIDE SYNTHASE; PHENOL DERIVATIVE; PROTEIN; PROTEOME; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; BIBENZYL DERIVATIVE; GUAIACOL; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING SITE; CATARACT; CATARACTOGENESIS; CONTROL GROUP; CONTROLLED STUDY; DENDROBIUM; DENDROBIUM AURANTIACUM; DRUG EFFECT; ENZYME INHIBITION; ENZYME KINETICS; GALACTOSEMIA; GENE EXPRESSION; HYDROGEN BOND; HYDROPHOBICITY; IC50; IN VITRO STUDY; MASS SPECTROMETRY; MICROSCOPE; MOLECULAR DOCKING; NONHUMAN; OPTICAL INSTRUMENTATION; PLANT STEM; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TURBIDITY; TWO DIMENSIONAL ELECTROPHORESIS; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; CHINESE MEDICINE; COMPLICATION; DRUG EFFECTS; ISOLATION AND PURIFICATION; LENS; OSMOTIC PRESSURE; PATHOLOGY; WISTAR RAT;

DENDROBIUM AURANTIACUM; DENDROBIUM AURANTIACUM VAR. DENNEANUM; RATTUS;

ANIMALS; ANTIOXIDANTS; BIBENZYLS; CATARACT; DENDROBIUM; DRUGS, CHINESE HERBAL; GALACTOSEMIAS; GUAIACOL; LENS, CRYSTALLINE; MEDICINE, CHINESE TRADITIONAL; MOLECULAR DOCKING SIMULATION; OSMOTIC PRESSURE; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84936761056     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.06.034     Document Type: Article

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