Review of research on Dendrobium, a prized folk medicine

Applied Microbiology and Biotechnology

Volumn 93, Issue 5, 2012, Pages 1795-1803

  Ng, Tzi Bun ^a   Liu, Jingyi ^b   Wong, Jack Ho ^a   Ye, Xiujuan ^c   Wing Sze, Stephen Cho ^b   Tong, Yao ^b   Zhang, Kalin Yanbo ^b  

^a Prince of Wales Hospital   (Hong Kong)

^b THE UNIVERSITY OF HONG KONG   (Hong Kong)

^c FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

Author keywords

Bioactivity; Constituents; Dendrobium; Medicinal plants

Indexed keywords

CHALCONE SYNTHASE; CONSTITUENTS; CYTOKININ OXIDASE; DENDROBIUM; HEPATOPROTECTIVE; MEDICINAL PLANTS; NEUROPROTECTIVE ACTIVITY; SUCROSE SYNTHASE;

BIOACTIVITY; PLANTS (BOTANY); SUGAR (SUCROSE);

POLYSACCHARIDES;

ALKALOID; ALLOAROMADENDRANE; ANGIOGENESIS INHIBITOR; ANTIFIBROTIC AGENT; ANTINEOPLASTIC AGENT; COPACAMPHANE; DENBINOBIN; DENDROBIUM CANDIDUM EXTRACT; DENDROBIUM HUOSHANENSE EXTRACT; DENDROBIUM OFFICINALE EXTRACT; DENDROFLORIN; DENDROMONILISIDE A; DENDROMONILISIDE B; DENDROMONILISIDE C; DENDROMONILISIDE D; FLUORENONE DERIVATIVE; GALACTOGLUCOMANNAN; GLYCOSIDE; MOSCATILIN; NARINGENIN; NEUROPROTECTIVE AGENT; PHENANTHRENE DERIVATIVE; PHENANTHRENEQUINONE; PICROTOXANE; PLANT EXTRACT; POLYSACCHARIDE; SESQUITERPENE DERIVATIVE; SG 168; STILBENE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIOXIDANT; BIOACTIVITY; ENZYME ACTIVITY; MEDICINAL PLANT; MEDICINE; MONOCOTYLEDON; RESEARCH WORK;

AMINO ACID SEQUENCE; ANTIANGIOGENIC ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ATOPIC DERMATITIS; CELLULAR IMMUNITY; DENDROBIUM; DENDROBIUM APHYLLUM; DENDROBIUM CANDIDUM; DENDROBIUM CHRYSANTHUM; DENDROBIUM CHRYSOTOXUM; DENDROBIUM CRYSTALLINUM; DENDROBIUM DENSIFLORUM; DENDROBIUM FIMBRIATUM; DENDROBIUM GRATIOSISSIMUM; DENDROBIUM HUOSHANENSE; DENDROBIUM LONGICORNU; DENDROBIUM NOBILE; DENDROBIUM SECUNDUM; DNA MICROARRAY; DNA SEQUENCE; GENE AMPLIFICATION; HUMAN; HUMORAL IMMUNITY; IMMUNOMODULATION; LIVER PROTECTION; NEUROPROTECTION; NONHUMAN; POLYMERASE CHAIN REACTION; SHORT SURVEY; SJOEGREN SYNDROME; THROMBOCYTE AGGREGATION INHIBITION; TRADITIONAL MEDICINE; UNSPECIFIED SIDE EFFECT;

BIOLOGICAL AGENTS; DENDROBIUM; HUMANS; MEDICINE, TRADITIONAL; PLANT EXTRACTS; PLANTS, MEDICINAL;

DENDROBIUM;

EID: 84862799637     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3829-7     Document Type: Short Survey

References (62)

1. Bi ZM, Wang ZT, Xu LS, Xu GJ (2003) Studies on the chemical constituents of Dendrobium fimbriatum. Yao Xue Xue Bao 38:526-529
2. Chang CC, Ku AF, Tseng YY, Yang WB, Fang JM, Wong CH (2010) 6,8-Di-C-glycosyl flavonoids from Dendrobium huoshanense. J Nat Prod 73:229-232
3. Chen CC, Wu LG, Ko FN, Teng CM (1994) Antiplatelet aggregation principles of Dendrobium loddigesii. J Nat Prod 57:1271-1274
4. Ding YP, Wu LS, Yu LW (1998) Optimized harvesting period for Dendrobium candidum. Chi J Chin Mater Med 23:458-460
5. Ding G, Ding XY, Shen J, Tang F, Liu DY, He J, Li XX, Chu BH (2005) Genetic diversity and molecular authentication of wild populations of Dendrobium officinale by RAPD. Yao Xue Xue Bao 40:1028-1032 (Pubitemid 43033076)
6. Fan Y, He X, Zhou S, Luo A, He T, Chun Z (2009) Composition analysis and antioxidant activity of polysaccharide from Dendrobium denneanum. Int J Biol Macromol 45:169-173
7. Gong YQ, Yang H, Liu Y, Liang AQ, Wang ZT, Xu LS, Hu ZB (2006) Studies on chemical constituents in stem of Dendrobium chrysotoxum. Zhongguo Zhong Yao Za Zhi 31:304-306
8. Hu JM, Chen JJ, Yu H, Zhao YX, Zhou J (2008a) Five new compounds from Dendrobium longicornu. Planta Med 74:535-539 (Pubitemid 351655972)
9. Hu JM, Chen JJ, Yu H, Zhao YX, Zhou J (2008b) Two novel bibenzyls from Dendrobium trigonopus. J Asian Nat Prod Res 10:653-657
10. Hua YF, Zhang M, Fu CX, Chen ZH, Chan GY (2004) Structural characterization of a 2-O-acetylglucomannan from Dendrobium officinale stem. Carbohydr Res 339:2219-2224 (Pubitemid 39165111)
11. Hwang JS, Lee SA, Hong SS, Han XH, Lee C, Kang SJ, Lee D, Kim Y, Hong JT, Lee MK, Hwang BY (2010) Phenanthrenes from Dendrobium nobile and their inhibition of the LPS-induced production of nitric oxide in macrophage RAW 264.7 cells. Bioorg Med Chem Lett 20:3785-3787
12. Ito M, Matsuzaki K, Wang J, Daikonya A, Wang NL, Yao XS, Kitanaka S (2010) New phenanthrenes and stilbenes from Dendrobium loddigesii. Chem Pharm Bull (Tokyo) 58:628-633
13. Jin J, Liang Y, Xie H, Zhang X, Yao X, Wang Z (2008) Dendroflorin retards the senescence of MRC-5 cells. Pharmazie 63:321-323 (Pubitemid 351543035)
14. Lau DT, Shaw PC, Wang J, But PP (2001) Authentication of medicinal Dendrobium species by the internal transcribed spacer of ribosomal DNA. Planta Med 67:456-460 (Pubitemid 32652584)
15. Li Y, Wang CL, Wang YJ, Wang FF, Guo SX, Yang JS, Xiao PG (2009a) Four new bibenzyl derivatives from Dendrobium candidum. Chem Pharm Bull (Tokyo) 57:997-999
16. Li Y, Wang CL, Wang YJ, Guo SX, Yang JS, Chen XM, Xiao PG (2009b) Three new bibenzyl derivatives from Dendrobium candidum. Chem Pharm Bull (Tokyo) 57:218-219
17. Li Y, Wang C, Wang F, Dong H, Guo S, Yang J, Xiao P (2010) Chemical constituents of Dendrobium candidum. Zhongguo Zhong Yao Za Zhi 35:1715-1719
18. Li Y, Li F, Gong Q, Wu Q, Shi J (2011) Inhibitory effects of Dendrobium alkaloids on memory impairment induced by lipopolysaccharide in rats. Planta Med 77:117-121
19. Liu CR, Pan XR (2002) The study of clinic and pharmacology in Dendrobium species. TCM Guangxi 25:6-8
20. Liu Q, Zhou W, Zhao RF (2005) 36 cases analysis for Sjögren's symptom by Chinese medicine. Chi Clin Rehabilitat 9:234-235
21. Liu J, He T, Chun Z (2009) DNA molecular identification of Herba Dendrobii and its adulterant species based on ITS sequence analysis. Zhongguo Zhong Yao Za Zhi 34:2853-2856
22. Liu XF, Zhu J, Ge SY, Xia LJ, Yang HY, Qian YT, Ren FZ (2011) Orally administered Dendrobium officinale and its polysaccharides enhance immune functions in BALB/c mice. Nat Prod Commun 6:867-870
23. Luo A, Ge Z, Fan Y, Luo A, Chun Z, He X (2011) In vitro and in vivo antioxidant activity of a water-soluble polysaccharide from Dendrobium denneanum. Molecules 16:1579-1592
24. Magwere T (2009) Escaping immune surveillance in cancer: is denbinobin the panacea? Br J Pharmacol 157:1172-1174
25. Meng H, Duan C, Xiao F, Yang S, Zha Y, Wen G (2011) Molecular cloning and expression analysis of sucrose synthase gene from Dendrobium officinale. Zhongguo Zhong Yao Za Zhi 36:833-837
26. Pan LH, Lu J, Luo JP, Zha XQ, Wang JH (2012) Preventive effect of a galactoglucomannan (GGM) from Dendrobium huoshanense on selenium-induced liver injury and fibrosis in rats. Exp Toxicol Pathol (in press)
27. PitakdanthamW, Sutabutra T, Chiemsombat P, Pitaksutheepong C (2010) Isolation and characterization of chalcone synthase gene isolated from Dendrobium sonia Earsakul. Pak J Biol Sci 13:1000-1005
28. Qian L, Ding G, Zhou Q, Feng Z, Ding X, Gu S, Wang Y, Li X, Chu B (2008) Molecular authentication of Dendrobium loddigesii Rolfe by amplification refractory mutation system (ARMS). Planta Med 74:470-473 (Pubitemid 351578811)
29. Sánchez-Duffhues G, Calzado MA, de Vinuesa AG, Appendino G, Fiebich BL, Loock U, Lefarth-Risse A, Krohn K, Muñoz E (2009) Denbinobin inhibits nuclear factor-kappaB and induces apoptosis via reactive oxygen species generation in human leukemic cells. Biochem Pharmacol 77:1401-1409
30. Sattayasai N, Sudmoon R, Nuchadomrong S, Chaveerach A, Kuehnle AR, Mudalige-Jayawickrama RG, BunyatratchataW(2009) Dendrobium findleyanum agglutinin: production, localization, anti-fungal activity and gene characterization. Plant Cell Rep 28:1243-1252
31. Shu Y, Zhang DM, Guo SX (2004) A new sesquiterpene glycoside from Dendrobium nobile Lindl. J Asian Nat Prod Res 6:311-314 (Pubitemid 39642701)
32. Sritularak B, Anuwat M, Likhitwitayawuid K (2011a) A new phenanthrenequinone from Dendrobium draconis. J Asian Nat Prod Res 13:251-255
33. Sritularak B, Duangrak N, Likhitwitayawuid K (2011b) A new bibenzyl from Dendrobium secundum. Z Naturforsch C 66:205-208
34. Sudmoon R, Sattayasai N, Bunyatratchata W, Chaveerach A, Nuchadomrong S (2008) Thermostable mannose-binding lectin from Dendrobium findleyanum with activities dependent on sulfhydryl content. Acta Biochim Biophys Sin (Shanghai) 40:811-818
35. Sze SC, Zhang KY, Shaw PC, But PP, Ng TB, Tong Y (2008) A DNA microarray for differentiation of (Fengdou Shihu) by its 5 S ribosomal DNA intergenic spacer region. Biotechnol Appl Biochem 49:149-154 (Pubitemid 351271079)
36. Takamiya T, Wongsawad P, Tajima N, Shioda N, Lu JF, Wen CL, Wu JB, Handa T, Iijima H, Kitanaka S, Yukawa T (2011) Identification of Dendrobium species used for herbal medicines based on ribosomal DNA internal transcribed spacer sequence. Biol Pharm Bull 34:7797-82
37. Tsai AC, Pan SL, Liao CH, Guh JH,Wang SW, Sun HL, Liu YN, Chen CC, Shen CC, Chang YL, Teng CM (2010) Moscatilin, a bibenzyl derivative from the India orchid Dendrobium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo. Cancer Lett 292:163-170
38. Wang M, Zhang CF, Wang ZT, Zhang M (2007) Studies on constituents of Dendrobium gratiosissimum. Zhongguo Zhong Yao Za Zhi 32:701-703
39. Wang L, Zhang CF,Wang ZT, Zhang M, Shao L, Xu LS (2008) Studies on chemical constituents of Dendrobium crystallinum. Zhongguo Zhong Yao Za Zhi 33:1847-1848
40. Wang L, Zhang CF, Wang ZT, Zhang M, Xu LS (2009a) Five new compounds from Dendrobium crystallinum. J Asian Nat Prod Res 11:903-911
41. Wang Y, Luo JP, Wei ZJ, Zhang JC (2009b) Molecular cloning and expression analysis of a cytokinin oxidase (DhCKX) gene in Dendrobium huoshanense. Mol Biol Rep 36:1331-1338
42. Wang JH, Zha XQ, Luo JP, Yang XF (2010a) An acetylated galactomannoglucan from the stems of Dendrobium nobile Lindl. Carbohydr Res 345:1023-1027
43. Wang Q, Gong Q, Wu Q, Shi J (2010b) Neuroprotective effects of Dendrobium on rat cortical neurons injured by oxygen-glucose deprivation and reperfusion. Phytomed 17:108-115
44. Wei X (2005) Alkaloid study on Dendrobium species. China Pharmaceut 19:445-447
45. Wu KG, Li TH, Chen CJ, Cheng HI, Wang TY (2011) A pilot study evaluating the clinical and immunomodulatory effects of an orally administered extract of Dendrobium huoshanense in children with moderate to severe recalcitrant atopic dermatitis. Int J Immunopathol Pharmacol 24:367-375
46. Xiao L, Ng TB, Feng YB, Yao T, Wong JH, Yao RM, Li L, Mo FZ, Xiao Y, Shaw PC, Li ZM, Sze SC, Zhang KY (2011) Dendrobium candidum extract increases the expression of aquaporin-5 in labial glands from patients with Sjögren's syndrome. Phytomed 18:194-198
47. Xu JH, Li L, Chen LZ (1995) Studies on the effects of white Dendrobium (Dendrobium candicum) and American ginseng (Panax quinquefolius) on nourishing the Yin and promoting glandular secretion in mice and rabbits. Chin Trad Herb Drug 6:79-80
48. Yang H, Chou GX, Wang ZT, Hu ZB, Xu LS (2004) Two new fluorenones from Dendrobium chrysotoxum. J Asian Nat Prod Res 6:35-38 (Pubitemid 38190220)
49. Yang L, Qin LH, Bligh SW, Bashall A, Zhang CF, Zhang M,Wang ZT, Xu LS (2006) A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities. Bioorg Med Chem 14:3496-3501
50. Yang L, Han H, Nakamura N, Hattori M, Wang Z, Xu L (2007) Bioguided isolation of antioxidants from the stems of Dendrobium aurantiacum var. denneanum. Phytother Res 21:696-698 (Pubitemid 47066789)
51. Yang LC, Deng H, Yi Y, Zhang XM, Wang YZ, Lin JQ (2010) Identification of medical Dendrobium herbs by ISSR marker. Zhong Yao Cai 33:1841-1844
52. Ye QH, Zhao WM, Qin GW (2003) New fluorenone and phenanthrene derivatives from Dendrobium chrysanthum. Nat Prod Res 17:201-205
53. Ye QH, Zhao WM, Qin GW (2004) Lignans from Dendrobium chrysanthum. J Asian Nat Prod Res 6:39-43
54. Yoon MY, Hwang JH, Park JH, Lee MR, Kim HJ, Park E, Park HR (2011) Neuroprotective effects of SG-168 against oxidative stress-induced apoptosis in PC12 cells. J Med Food 14:120-127
55. Zhang YB, Wang J, Wang ZT, But PP, Shaw PC (2003) DNA microarray for identification of the herb of Dendrobium species from Chinese medicinal formulations. Planta Med 69:1172-1174 (Pubitemid 38223367)
56. Zhang X, Gao H, Wang NL, Yao XS (2006) Three new bibenzyl derivatives from Dendrobium nobile. J Asian Nat Prod Res 8:113-118 (Pubitemid 43879871)
57. Zhang X, Xu JK, Wang J, Wang NL, Kurihara H, Kitanaka S, Yao XS (2007) Bioactive bibenzyl derivatives and fluorenones from Dendrobium nobile. J Nat Prod 70:24-28
58. Zhang CF, Shao L, Huang WH, Wang L, Wang ZT, Xu LS (2008a) Phenolic components from herbs of Dendrobium aphyllum. Zhongguo Zhong Yao Za Zhi 33:2922-2925
59. Zhang X, Tu FJ, Yu HY, Wang NL, Wang Z, Yao XS (2008b) Copacamphane, picrotoxane and cyclocopacamphane sesquiterpenes from Dendrobium nobile. Chem Pharm Bull (Tokyo) 56:854-857 (Pubitemid 351872258)
60. Zhao C, Liu Q, Halaweish F, Shao B, Ye Y, Zhao W (2003) Copacamphane, picrotoxane, and alloaromadendrane sesquiterpene glycosides and phenolic glycosides from Dendrobium moniliforme. J Nat Prod 66:1140-1143 (Pubitemid 37034058)
61. Zheng Y (2005) Shihu in China Pharmacopoeia. Chemical Technology, Beijing, pp 61-63
62. Zheng WP, Tang YP, Zhi F, Lou FC (2000) Dihydroayapin, a new coumarin compound from Dendrobium densiflorum. J Asian Nat Prod Res 2:301-304