Aldose reductase deficiency protects sugar-induced lens opacification in rats

Chemico-Biological Interactions

Volumn 191, Issue 1-3, 2011, Pages 346-350

  Reddy, Aramati B M ^a   Tammali, Ravinder ^a   Mishra, Rakesh ^a   Srivastava, Shriram ^a   Srivastava, Satish K ^a   Ramana, Kota V ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Aldose reductase; Cataract; Lens opacification; Oxidative stress; SiRNA knock down rats

Indexed keywords

ALDEHYDE REDUCTASE; ALDEHYDE REDUCTASE INHIBITOR; ENZYME INHIBITOR; GLUCOSE; GLUTATHIONE; SMALL INTERFERING RNA; SORBITOL; UNCLASSIFIED DRUG;

ALDEHYDE REDUCTASE DEFICIENCY; ANIMAL CELL; CATARACT; CATARACTOGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME DEFICIENCY; EX VIVO STUDY; FEMALE; GENOTYPE; GLUCOSE BLOOD LEVEL; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TISSUE HOMOGENATE;

ALDEHYDE REDUCTASE; ANIMALS; BASE SEQUENCE; CATARACT; FEMALE; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; HYPERGLYCEMIA; LENS, CRYSTALLINE; MALE; MOLECULAR SEQUENCE DATA; RATS; RNA, SMALL INTERFERING;

ANIMALIA; MUS; MUS MUSCULUS; RATTUS;

EID: 79957580933     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.02.028     Document Type: Conference Paper

References (27)

1. H.G. Hers, The mechanism of the transformation of glucose in fructose in the seminal vesicles, Biochim. Biophys. Acta 22 (1956) 202-203.
2. A. Bhatnagar, S.K. Srivastava, Biochemical aldose reductase: congenial and injurious profiles of an enigmatic enzyme, Med. Metab. Biol. 48 (1992) 91-121.
3. P.J. Dyck, P.K. Thomas, Diabetic Neuropathy, W. B. Saunders, Philadelphia, 1999.
4. M. Brownlee, Biochemistry and molecular biology of diabetic complications, Nature 414 (2001) 813-820. (Pubitemid 34000785)
5. J.A. Beckman, M.A. Creager, P. Libby, Diabetic and atherosclerosis: epidemiology, pathophysiology, and management, JAMA 287 (2002) 2570-2581.
6. S.K Srivastava, K.V. Ramana, A. Bhatnagar, Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options, Endocr. Rev. 26 (2005) 380-392.
7. N. Hotta, H. Kakuta, F. Ando, N. Sakamoto, Current progress in clinical trials of aldose reductase inhibitors in Japan, Exp. Eye Res. 50 (1990) 625-628.
8. D. Stribling, Clinical trials with aldose reductase inhibitors, Exp. Eye Res. 50 (1990) 621-624.
9. N.E. Pitts, K. Gundersen, D.J. Mehta, F. Vreeland, G.L. Shaw, M.J. Peterson, J. Collier, Aldose reductase inhibitors in clinical practice. Preliminary studies on diabetic neuropathy and retinopathy, Drugs 32 (1986) 30-35. (Pubitemid 17186624)
10. A.Y. Lee, S.K. Chung, S.S. Chung, Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens, Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 2780-2784.
11. S.M. Lee, S.Z. Schade, C.C. Doughty, Aldose reductase, NADPH and NADP in normal, galactosefed and diabetic rat lens, Biochim. Biophys. Acta 841 (1985) 247-253. (Pubitemid 16217194)
12. W.M. Ross, M.O. Creighton, J.R. Trevithick, P.J. Stewart-DeHaan, M. SanwaI, Modelling cortical cataractogenesis: VI. Induction by glucose in vitro or in diabetic rats: prevention and reversal by glutathione, Exp. Eye Res. 37 (1983) 559-573. (Pubitemid 14191828)
13. S.K. Srivastava, N.H. Ansari, Prevention of sugar-induced cataractogenesis in rats by butylated hydroxytoluene, Diabetes 37 (1988) 1505-1508.
14. N.H. Ansari, S.K. Srivastava, Aliopurinol promotes and butylated hydroxy toluene prevents sugar induced cataractogenesis, Biochem. Biophys. Res. Commun. 168 (1990) 939-943. (Pubitemid 20175970)
15. S. Richer, Antioxidants and the eye, Int. Ophthalmol. Clin. 40 (2000) 1-16.
16. S.D. Varma, J.H. Kinoshita, The absence of cataracts in mice with congenital hyperglycemia, Exp. Eye Res. 19 (1974) 577-582.
17. C.M. Yeung, A.C. Lo, A.K. Cheung, S.S. Chung, D. Wong, S.K. Chung, More severe type 2 diabetes-associated ischemic stroke injury is alleviated in aldose reductase-deficient mice, J. Neurosci. Res. 88 (2010) 2026-2034.
18. A.K. Cheung, M.K. Fung, A.C. Lo, T.T. Lam, K.F. So, S.S. Chung, S.K. Chung, Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice, Diabetes 54 (2005) 3119-3125.
19. D. Chandra, K.V. Ramana, L. Wang, B.N. Christensen, A. Bhatnagar, S.K. Srivastava, Inhibition of fiber cell globulization and hyperglycemia-induced lens opacification by aminopeptidase inhibitor bestatin, Invest. Ophthalmol. Vis. Sci. 2002 (43) (2002) 2285-2292. (Pubitemid 34700660)
20. A. Bhatnagar, N.H. Ansari, A. Zacarias, S.K. Srivastava, Digital image analysis of cultured rat lens during oxidative stress-induced cataractogenesis, Exp. Eye Res. 57 (1993) 385-391.
21. S. Srivastava, A. Chandra, L.F. Wang, W.E. Seifert, B.B. DaGue, N.H. Ansari, S.K. Srivastava, A. Bhatnagar, Metabolism of the lipid peroxidation product, 4-hydoxy-trans-2-nonenal, in isolated perfused rat heart, J. Biol. Chem. 273 (1998) 10893-10900. (Pubitemid 28204926)
22. B. Charreau, L. Tesson, J. Soulillou, C. Pourcel, I. Anegon, Transgenesis in rats: technical aspects and models, Transgenic Res. 5 (1996) 223-234. (Pubitemid 26310375)
23. H. Hasuwa, K. Kaseda, T. Einarsdottir, M. Okabe, Small interfering RNA and gene silencing in transgenic mice and rats, FEBS Lett. 532 (2002) 227-230. (Pubitemid 35375894)
24. H.T. Ho, S.K. Chung, J.W. Law, B.C. Ko, S.C. Tam, H.L. Brooks, M.A. Knepper, S.S. Chung, Aldose reductase-deficient mice develop nephrogenic diabetes insipidus, Mol. Cell. Biol. 20 (2000) 5840-5846. (Pubitemid 30613033)
25. J.H. Kinoshita, P. Kador, M. Catiles, Aldose reductase in diabetic cataracts, JAMA 246 (1981) 257-261. (Pubitemid 11074896)
26. S. Yagihashi, S.I. Yamagishi, R.R. Wada, M. Baba, T.C. Hohman, C. Yabe-Nishimura, Y. Kokai, Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor, Brain 124 (2001) 2448-2458. (Pubitemid 33134934)
27. Z. Song, D.T. Fu, Y.S. Chan, S. Leung, S.S. Chung, S.K. Chung, Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress, Mol. Cell. Neurosci. 23 (2003) 638-647. (Pubitemid 36970224)