Association of adenosine receptor gene polymorphisms and in vivo adenosine A1 receptor binding in the human brain

Neuropsychopharmacology

Volumn 39, Issue 13, 2014, Pages 2989-2999

  Hohoff, Christa ^a   Garibotto, Valentina ^b   Elmenhorst, David ^b   Baffa, Anna ^a   Kroll, Tina ^b   Hoffmann, Alana ^a   Schwarte, Kathrin ^a   Zhang, Weiqi ^a   Arolt, Volker ^a   Deckert, Jürgen ^c   Bauer, Andreas ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

8-CYCLOPENTA-3-(3-FLUOROPROPYL)-1-PROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; FLUORODEOXYGLUCOSE F 18; PROTEIN BINDING; XANTHINE DERIVATIVE;

ADULT; BRAIN; DRUG EFFECTS; FEMALE; GENETIC LINKAGE; GENETICS; GENOTYPE; HUMAN; MALE; METABOLISM; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; SCINTISCANNING; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

ADULT; BRAIN; FEMALE; FLUORODEOXYGLUCOSE F18; GENETIC LINKAGE; GENOTYPE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; PURINERGIC P1 RECEPTOR ANTAGONISTS; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; XANTHINES; YOUNG ADULT;

EID: 84936080751     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.150     Document Type: Article

References (51)

1. Alsene K, Deckert J, Sand P, de Wit H (2003). Association between A2a receptor gene polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology 28: 1694-1702.
2. Ascherio A, Chen H (2003). Caffeinated clues from epidemiology of Parkinson's disease. Neurology 61: S51-S54.
3. Baiano M, Perlini C, Rambaldelli G, Cerini R, Dusi N, Bellani M et al (2008). Decreased entorhinal cortex volumes in schizophrenia. Schizophr Res 102: 171-180.
4. Barrett JC, Fry B, Maller J, Daly MJ (2005). Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
5. 18F]CPFPX and positron emission tomography. Neuroimage 19: 1760-1769.
6. 1 adenosine receptor density caused by glioma invasion. J Nucl Med 46: 450-454.
7. Benjamini Y, Hochberg Y (1995). Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 57: 298-300.
8. 2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation. Br J Pharmacol 165: 1904-1913.
9. 2A receptor heteromers in human brain caudate nucleus. J Neurochem 114: 972-980.
10. 2A and DRD2 polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology 33: 2791-2800.
11. 2A adenosine receptors. Physiol Behav 109: 1-7.
12. Cunha RA (2001). Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors. Neurochem Int 38: 107-125.
13. 1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease. Mol Psychiatry 3: 81-85.
14. 18F-CPFPX and PET. J Nucl Med 53: 1723-1729.
15. 18F]CPFPX and PET. Eur J Nucl Med Mol Imaging 34: 1061-1070.
16. 1 adenosine receptor binding in the human brain: a positron emission tomography study. J Neurosci 27: 2410-2415.
17. Ferré S, Ciruela F, Quiroz C, Luján R, Popoli P, Cunha RA et al (2007). Adenosine receptor heteromers and their integrative role in striatal function. Scientific World J 7: 74-85.
18. Fredholm BB, Chen JF, Cunha RA, Svenningsson P, Vaugeois JM (2005). Adenosine and brain function. Int Rev Neurobiol 63: 191-270.
19. 2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder. Eur Child Adolesc Psychiatry 19: 67-74.
20. Gomes CV, Kaster MP, Tomé AR, Agostinho PM, Cunha RA (2011). Adenosine receptors and brain diseases: neuroprotection and neurodegeneration. Biochim Biophys Acta 1808: 1380-1399.
21. 1) polymorphisms with schizophrenia in a Japanese population. Psychiatr Genet 19: 328-335.
22. Hamilton JP, Etkin A, Furman DJ, Lemus MG, Johnson RF, Gotlib IH (2012). Functional neuroimaging of major depressive disorder: a meta-analysis and new integration of base line activation and neural response data. Am J Psychiatry 169: 693-703.
23. Hohoff C, Domschke K, Schwarte K, Spellmeyer G, Vögele C, Hetzel G et al (2009). Sympathetic activity relates to adenosine A(2A) receptor gene variation in blood-injury phobia. J Neural Transm 116: 659-662.
24. 2A receptor gene haplotype is associated with migraine with aura. Cephalalgia 27: 177-181.
25. 2A receptor gene variants. Am J Med Genet B Neuropsychiatr Genet 139B: 42-44.
26. Hohoff C, Mullings EL, Heatherley SV, Freitag CM, Neumann LC, Domschke K et al (2010). Adenosine A(2A) receptor gene: evidence for association of risk variants with panic disorder and anxious personality. J Psychiatr Res 44: 930-937.
27. 18F]CPFPX): a potent and selective A(1)-adenosine receptor antagonist for in vivo imaging. J Med Chem 45: 5150-5156.
28. Ising M, Höhne N, Siebertz A, Parchmann AM, Erhardt A, Keck M (2012). Stress response regulation in panic disorder. Curr Pharm Des 18: 5675-5684.
29. 1 and A2 adenosine receptor binding and on mRNA levels in rat brain. Naunyn Schmiedebergs Arch Pharmacol 347: 407-414.
30. Kahn M, Sheppes G, Sadeh A (2013). Sleep and emotions: bidirectional links and underlying mechanisms. Int J Psychophysiol 89: 218-228.
31. Logan J, Fowler JS, Volkow ND, Wang GJ, Ding YS, Alexoff DL (1996). Distribution volume ratios without blood sampling from graphical analysis of PET data. J Cereb Blood Flow Metab 16: 834-840.
32. Maia L, de Mendonça A (2002). Does caffeine intake protect from Alzheimer's disease? Eur J Neurol 9: 377-382.
33. Mandel HG (2002). Update on caffeine consumption, disposition and action. Food Chem Toxicol 40: 1231-1234.
34. 18F]CPFPX and PET. J Cereb Blood Flow Metab 24: 323-333.
35. 18F]CPFPX and PET: an equilibrium approach. Neuroimage 24: 1192-1204.
36. 18F]CPFPX PET study in humans. Neurobiol Aging 28: 1914-1924.
37. Minkel JD, Banks S, Htaik O, Moreta MC, Jones CW, McGlinchey EL et al (2012). Sleep deprivation and stressors: evidence for elevated negative affect in response to mild stressors when sleep deprived. Emotion 12: 1015-1020.
38. Moghaddam B, Homayoun H (2008). Divergent plasticity of prefrontal cortex networks. Neuropsychopharmacology 33: 42-55.
39. Paul S, Elsinga PH, Ishiwata K, Dierckx RA, van Waarde A (2011a). Adenosine A(1) receptors in the central nervous system: their functions in health and disease, and possible elucidation by PET imaging. Curr Med Chem 18: 4820-4835.
40. Paul S, Khanapur S, Rybczynska AA, Kwizera C, Sijbesma JW, Ishiwata K et al (2011b). Small-animal PET study of adenosine A(1) receptors in rat brain: blocking receptors and raising extracellular adenosine. J Nucl Med 52: 1293-1300.
41. Ribeiro JA, Sebastiao AM, de Mendonca A (2002). Adenosine receptors in the nervous system: pathophysiological implications. Prog Neurobiol 68: 377-392.
42. Rich BA, Carver FW, Holroyd T, Rosen HR, Mendoza JK, Cornwell BR et al (2011). Different neural pathways to negative affect in youth with pediatric bipolar disorder and severe mood dysregulation. J Psychiatr Res 45: 1283-1294.
43. 1 polymorphisms and habitual level of caffeine consumption. Neuropsychopharmacology 35: 1973-1983.
44. 1) receptors by caffeine treatment. Neurosci Lett 103: 275-280.
45. 2A) contributes to individual sensitivity to caffeine effects on sleep. Clin Pharmacol Ther 81: 692-698.
46. Schmidt NB, Zvolensky MJ, Maner JK (2006). Anxiety sensitivity: prospective prediction of panic attacks and Axis I pathology. J Psychiatr Res 40: 691-699.
47. Svarer C, Madsen K, Hasselbalch SG, Pinborg LH, Haugbl S, Frkjaer VG et al (2005). MR-based automatic delineation of volumes of interest in human brain PET images using probability maps. Neuroimage 24: 969-979.
48. Tang Z, Diamond MA, Chen JM, Holly TA, Bonow RO, Dasgupta A et al (2007). Polymorphisms in adenosine receptor genes are associated with infarct size in patients with ischemic cardiomyopathy. Clin Pharmacol Ther 82: 435-440.
49. 1 receptor gene variants associated with post-traumatic seizures after severe TBI. Epilepsy Res 90: 259-272.
50. Wei CJ, Li W, Chen JF (2011). Normal and abnormal functions of adenosine receptors in the central nervous system revealed by genetic knockout studies. Biochim Biophys Acta 1808: 1358-1379.
51. Willeit M, Praschak-Rieder N (2010). Imaging the effects of genetic polymorphisms on radioligand binding in the living human brain: a review on genetic neuroreceptor imaging of monoaminergic systems in psychiatry. Neuroimage 53: 878-892.