Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI

Epilepsy Research

Volumn 90, Issue 3, 2010, Pages 259-272

  Wagner, Amy K ^a,b   Miller, Megan A ^a   Scanlon, Joelle ^a   Ren, Dianxu ^c   Kochanek, Patrick M ^a,b   Conley, Yvette P ^b,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

A1AR; Adenosine; ADORA1; Brain injury; Genetic susceptibility; Post traumatic seizure

Indexed keywords

ADENOSINE A1 RECEPTOR;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE MAP; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRAUMATIC BRAIN INJURY; TRAUMATIC EPILEPSY; ADOLESCENT; AGED; BRAIN INJURY; COMPLICATION; EPILEPSY, POST-TRAUMATIC; GENETIC PREDISPOSITION; GENETICS; HAPLOTYPE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATIENT SELECTION; RETROSPECTIVE STUDY; SEIZURES;

ADOLESCENT; ADULT; AGED; ALLELES; BRAIN INJURIES; EPILEPSY, POST-TRAUMATIC; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATIENT SELECTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, ADENOSINE A1; RETROSPECTIVE STUDIES; SEIZURES;

EID: 77955057138     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2010.06.001     Document Type: Article

References (42)

1. Andine, Rudolphi K.A., Fredholm B.B., Hagberg H. Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia. Br. J. Pharmacol. 1990, 100:814-818.
2. Annegers J.F., Hauser W.A., Coan S.P., Rocca W.A. A population-based study of seizures after traumatic brain injuries. N. Engl. J. Med. 1998, 33:20-24.
3. Armstrong K.K., Sahgal V., Bloch R., Armstrong K.J., Heinemann A. Rehabilitation outcomes in patients with posttraumatic epilepsy. Arch. Phys. Med. Rehabil. 1990, 71:156-160.
4. Avsar E., Empson R.M. Adenosine acting via A1 receptors, controls the transition to status epilepticus-like behaviour in an in vitro model of epilepsy. Neuropharmacology 2004, 47:427-437.
5. Bell M.J., Robertson C.S., Kochanek P.M., Goodman J.C., Gopinath S.P., Carcillo J.A., Clark R.S., Marion D.W., Mi Z., Jackson E.K. Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury. Crit. Care Med. 2001, 29(2):399-404.
6. Bullock R., Chesnut R.M., Clifton G., Ghajar J., Marion D.W., Narayan R.K., Newell D.W., Pitts L.H., Rosner M.J., Wilberger J.W. Guidelines for the management of severe head injury. Eur. J. Emerg. Med. 1996, 3:109-127.
7. Cavalleri G.L., Walley N.M., Soranzo N., Mulley J., Doherty C.P., Kapoor A., Depondt C., Lynch J.M., Scheffer I.E., Heils A., Gehrmann A., Kinirons P., Gandhi S., Satishchandra P., Wood N.W., Anand A., Sander T., Berkovic S.F., Delanty N., Goldstein D.B., Sisodiya S.M. A multicenter study of BRD2 as a risk factor for juvenile myoclonic epilepsy. Epilepsia 2007, 48:706-712.
8. Ciruela F., Casadó V., Rodrigues R.J., Luján R., Burgueño J., Canals M., Borycz J., Rebola N., Goldberg S.R., Mallol J., Cortés A., Canela E.I., López-Giménez J.F., Milligan G., Lluis C., Cunha R.A., Ferré S., Franco R. Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. J. Neurosci. 2006, 26(7):2080-2087.
9. Clifton G.L., Allen S., Barrodale P., Plenger P., Berry J., Koch S., Fletcher J., Hayes R.L., Choi S.C. A phase II study of moderate hypothermia in severe brain injury. J. Neurotrauma 1993, 10:263-271.
10. Deckert J., Jorgensen M.B. Evidence for pre- and postsynaptic localization of adenosine A1 receptors in the CA1 region of rat hippocampus: a quantitative autoradiographic study. Brain Res. 1988, 446:161-164.
11. D'Ambrosio R., Fairbanks J.P., Fender J.S., Born D.E., Doyle D.L., Miller J.W. Post-traumatic epilepsy following fluid percussion injury in the rat. Brain 2004, 127:304-314.
12. Dikmen S.S., Temkin N.R., Miller B., Machamer J., Winn H.R. Neurobehavioral effects of phenytoin prophylaxis of posttraumatic seizures. JAMA 1991, 265:1271-1277.
13. Englander J., Bushnik T., Duong T.T., Cifu D.X., Zafonte R., Wright J., Hughes R., Bergman W. Analyzing risk factors for late posttraumatic seizures: a prospective, multicenter investigation. Arch. Phys. Med. Rehabil. 2003, 84:365-373.
14. Fedele D.E., Gouder N., Güttinger M., Gabernet L., Scheurer L., Rülicke T., Crestani F., Boison D. Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation. Brain 2005, 128:2383-2395.
15. Fedele D.E., Li T., Lan J.Q., Fredholm B.B., Boison D. Adenosine A1 receptors are crucial in keeping an epileptic focus localized. Exp. Neurol. 2006, 200(1):184-190.
16. Franco R., Ferré S., Agnati L., Torvinen M., Ginés S., Hillion J., Casadó V., Lledó P., Zoli M., Lluis C., Fuxe K. Evidence for adenosine/dopamine receptor interactions: indications for heteromerization. Neuropsychopharmacology 2000, 23(4 Suppl.):S50-S59. (Review).
17. Frey L.C. Epidemiology of posttraumatic epilepsy: a critical review. Epilepsia 2003, 44(Suppl. 10):11-17.
18. Haltiner A.M., Temkin N.R., Dikmen S.S. Risk of seizure recurrence after the first late posttraumatic seizure. Arch. Phys. Med. Rehabil. 1997, 78:835-840.
19. Herzog A.G. Catamenial epilepsy: definition, prevalence pathophysiology and treatment. Seizure 2008, 17(2):151-159. (Review).
20. Hernandez-Saavedra D., McCord J.M. Association of a new intronic polymorphism of the SOD2 gene (G1677T) with cancer. Cell Biochem. Funct. 2009, 27:223-227.
21. Hung C.C., Tai J.J., Lin C.J., Lee M.J., Liou H.H. Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response. Pharmacogenomics 2005, 6:411-417.
22. Jennett B., Bond M. Assessment of outcome after severe brain damage. Lancet 1975, 1:480-484.
23. Ji T.H., Grossmann M., Ji I. G protein-coupled receptors. J. Biol. Chem. 1998, 273:17299-17302.
24. Kochanek P.M., Vagni V.A., Janesko K.L., Washington C.B., Crumrine P.K., Garman R.H., Jenkins L.W., Clark R.S., Homanics G.E., Dixon C.E., Schnermann J., Jackson E.K. Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury. J. Cereb. Blood Flow Metab. 2006, 26:565-575.
25. Lee S.T., Lui T.N., Wong C.W., Yeh Y.S., Tzaan W.C. Early seizures after moderate closed head injury. Acta Neurochir. (Wien.) 1995, 137:151-154.
26. MacKenzie A., Quinn J. A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:15251-15255.
27. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988, 16:1215.
28. Nilsson P., Ronne-Engstrom E., Flink R., Ungerstedt U., Carlson H., Hillered L. Epileptic seizure activity in the acute phase following cortical impact trauma in rat. Brain Res. 1994, 637:227-232.
29. Olah M.E., Stiles G.L. The role of receptor structure in determining adenosine receptor activity. Pharmacol. Ther. 2000, 85(2):55-75.
30. Rhodes M.E., Frye C.A. Actions at GABA(A) receptors in the hippocampus may mediate some antiseizure effects of progestins. Epilepsy Behav. 2005, 6:320-327.
31. Robertson C.L., Bell M.J., Kochanek P.M., Adelson P.D., Ruppel R.A., Carcillo J.A., Wisniewski S.R., Mi Z., Janesko K.L., Clark R.S., Marion D.W., Graham S.H., Jackson E.K. Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: association with severity of injury and excitotoxicity. Crit. Care Med. 2001, 29:2287-2293.
32. Rosen N., Chalifa-Caspi V., Shmueli O., Adato A., Lapidot M., Stampnitzky J., Safran M., Lancet D. GeneLoc: exon-based integration of human genome maps. Bioinformatics 2003, 19(S1):i222-i224.
33. Rudolphi K.A., Schubert P., Parkinson F.E., Fredholm B.B. Adenosine and brain ischemia. Cerebrovasc. Brain Metab. Rev. 1992, 4:346-369. (Review).
34. Silver J., Miller J.H. Regeneration beyond the glial scar. Nat. Rev. Neurosci. 2004, 5:146-156.
35. Smith K.R., Goulding P.M., Wilderman D., Goldfader P.R., Holterman-Hommes P., Wei F. Neurobehavioral effects of phenytoin and carbamazepine in patients recovering from brain trauma: a comparative study. Arch. Neurol. 1994, 51:653-660.
36. Stephens M., Smith N., Donnelly P. A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 2001, 68:978-989.
37. Temkin N.R., Dikmen S.S., Wilensky A.J., Keihm J., Chabal S., Winn H.R. A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures. N. Engl. J. Med. 1990, 323:497-502.
38. Temkin N.R. Prophylactic Anticonvulsants after neurosurgery. Epilepsy Curr. 2002, 2:105-107.
39. Temkin N.R. Risk factors for posttraumatic seizures in adults. Epilepsia 2003, 44(Suppl. 10):18-20.
40. Thurman D.J., Alverson C., Dunn K.A., Guerrero J., Sniezek J.E. Traumatic brain injury in the United States: a public health perspective. J. Head Trauma Rehabil. 1999, 14:602-615.
41. Vaughan K.T., Weber F.E., Ried T., Ward D.C., Reinach F.C., Fischman D.A. Human myosin-binding protein H (MyBP-H): complete primary sequence, genomic organization, and chromosomal localization. Genomics 1993, 16(1):34-40.
42. Vespa P.M., Miller C., McArthur D., Eliseo M., Etchepare M., Hirt D., Glenn T.C., Martin N., Hovda D. Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis. Crit. Care Med. 2007, 35(12):2830-2836.