Interindividual variation in anxiety response to amphetamine: Possible role for adenosine A2A receptor gene variants

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 139 B, Issue 1, 2005, Pages 42-44

  Hohoff, Christa ^a   McDonald, Jennifer M ^b   Baune, Bernhard T ^a   Cook, Edwin H ^b   Deckert, Jürgen ^a   De Wit, Harriet ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Adenosine A2A receptor gene polymorphisms; Anxiety; Dopamine D2 receptor; Drug response

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; CENTRAL STIMULANT AGENT; DEXAMPHETAMINE; DIMER; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR;

ADENOSINE A2A RECEPTOR GENE; ADULT; ANXIETY; ARTICLE; DNA POLYMORPHISM; DRUG RESPONSE; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AMPHETAMINE; ANXIETY; CENTRAL NERVOUS SYSTEM STIMULANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, ADENOSINE A2A; RECEPTORS, DOPAMINE D2; VARIATION (GENETICS);

EID: 27644583300     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30228     Document Type: Article

References (16)

1. 2A receptor gene polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology 28:1694-1702.
2. Brauer LH, de Wit H. 1996. Subjective responses to d-amphetamine alone and after pimozide pretreatment in normal healthy volunteers. Biol Psychiatry 39:26-32.
3. 2 receptor-receptor heteromerization: Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J Biol Chem 278:46741-46749.
4. Charney DS, Heninger GR, Jatlow PI. 1985. Increased anxiogenic effects of caffeine in panic disorder. Arch Gen Psychiatry 42:233-243.
5. Crabbe JC, Jarvik LF, Liston EH, Jenden DJ. 1983. Behavioral responses to amphetamine in identical twins. Acta Genet Med Gemellol (Roma) 32:139-149.
6. de Wit H, Griffiths RR. 1991. Methods of assessing the abuse liability of sedatives in humans. Drug Alcohol Depend 28:83-111.
7. de Wit H, Uhlenhuth EH, Johanson CE. 1986. Individual differences in the behavioral and subjective effects of amphetamine and diazepam. Drug Alcohol Depend 16:341-360.
8. 2A gene to the development of disease. Mol Psychiatry 3:81-85.
9. 2A receptors in schizophrenia. Neuro Report 14:313-316.
10. 2A receptor and panic disorder. Neuropsychopharmacology 29:558-565.
11. Honey G, Bullmore E. 2004. Human pharmacological MRI. Trends Pharmacol Sci 25:366-374.
12. 2A receptor. Nature 388:674-682.
13. Lott DC, Kim SJ, Cook EH Jr, de Wit H. 2005. Dopamine transporter gene associated with diminished subjective response to amphetamine. Neuropsychopharmacology 30:602-609.
14. Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF, Kolachana B, Callicott JH, Weinberger DR. 2003. Catechol O-methyl-transferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci USA 100:6186-6191.
15. McNair D, Lorr M, Droppleman DL. 1971. Profile of Mood States. San Diego: Educational and Industrial Testing Service.
16. Pierce RC, Kalivas PW. 1997. A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants. Brain Res Rev 25:192-216.