-
2
-
-
44449096081
-
High-throughput evaluation of relative cell permeability between peptoids and peptides
-
Tan NC, Yu P, Kwon YU, Kodadek T. 2008. High-throughput evaluation of relative cell permeability between peptoids and peptides. Bioorg Med Chem 16:5853-5861. http://dx.doi.org/10.1016/j.bmc.2008.04.074.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 5853-5861
-
-
Tan, N.C.1
Yu, P.2
Kwon, Y.U.3
Kodadek, T.4
-
3
-
-
77957077791
-
A novel Trp-rich model antimicrobial peptide with increased protease stability
-
Bang JK, Hai Y, Lee EK, Shin SY. 2010. A novel Trp-rich model antimicrobial peptide with increased protease stability. Bull Korean Chem Soc 31:2509-2513. http://dx.doi.org/10.5012/bkcs.2010.31.9.2509.
-
(2010)
Bull Korean Chem Soc
, vol.31
, pp. 2509-2513
-
-
Bang, J.K.1
Hai, Y.2
Lee, E.K.3
Shin, S.Y.4
-
4
-
-
0028033882
-
Proteolytic studies of homologous peptide and N-substituted glycine peptoid oligomers
-
Miller SM, Simon RJ, Ng S, Zuckermann RN, Kerr JM, Moos WH. 1994. Proteolytic studies of homologous peptide and N-substituted glycine peptoid oligomers. Bioorg Med Chem Lett 4:2657-2662. http://dx.doi.org/10.1016/S0960-894X(01)80691-0.
-
(1994)
Bioorg Med Chem Lett
, vol.4
, pp. 2657-2662
-
-
Miller, S.M.1
Simon, R.J.2
Ng, S.3
Zuckermann, R.N.4
Kerr, J.M.5
Moos, W.H.6
-
5
-
-
38149143037
-
Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
-
Chongsiriwatana NP, Patch JA, Czyzewski AM, Dohm MT, Ivankin A, Gidalevitz D, Zuckermann RN, Barron AE. 2008. Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc Natl Acad Sci U S A 105:2794-2799. http://dx.doi.org/10.1073/pnas.0708254105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2794-2799
-
-
Chongsiriwatana, N.P.1
Patch, J.A.2
Czyzewski, A.M.3
Dohm, M.T.4
Ivankin, A.5
Gidalevitz, D.6
Zuckermann, R.N.7
Barron, A.E.8
-
6
-
-
84896864559
-
Small molecular antibacterial peptoid mimics: The simpler the better!
-
Ghosh C, Manjunath GB, Akkapeddi P, Yarlagadda V, Hoque J, Uppu DS, Konai MM, Haldar J. 2014. Small molecular antibacterial peptoid mimics: the simpler the better! J Med Chem 57:1428-1436. http://dx.doi.org/10.1021/jm401680a.
-
(2014)
J Med Chem
, vol.57
, pp. 1428-1436
-
-
Ghosh, C.1
Manjunath, G.B.2
Akkapeddi, P.3
Yarlagadda, V.4
Hoque, J.5
Uppu, D.S.6
Konai, M.M.7
Haldar, J.8
-
8
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB. 2000. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc Natl Acad Sci U S A 97:13003-13008. http://dx.doi.org/10.1073/pnas.97.24.13003.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
9
-
-
0032539598
-
A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery
-
Murphy JE, Uno T, Hamer JD, Cohen FE, Dwarki V, Zuckermann RN. 1998. A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery. Proc Natl Acad Sci U S A 95:1517-1522. http://dx.doi.org/10.1073/pnas.95.4.1517.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1517-1522
-
-
Murphy, J.E.1
Uno, T.2
Hamer, J.D.3
Cohen, F.E.4
Dwarki, V.5
Zuckermann, R.N.6
-
10
-
-
84896500814
-
Learning from host-defense peptides: Cationic, amphipathic peptoids with potent anticancer activity
-
Huang W, Seo J, Willingham SB, Czyzewski AM, Gonzalgo ML, Weissman IL, Barron AE. 2014. Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity. PLoS One 9:e90397. http://dx.doi.org/10.1371/journal.pone.0090397.
-
(2014)
PLoS One
, vol.9
-
-
Huang, W.1
Seo, J.2
Willingham, S.B.3
Czyzewski, A.M.4
Gonzalgo, M.L.5
Weissman, I.L.6
Barron, A.E.7
-
11
-
-
84887012022
-
Antibody-mimetic peptoid nanosheets for molecular recognition
-
Olivier GK, Cho A, Sanii B, Connolly MD, Tran H, Zuckermann RN. 2013. Antibody-mimetic peptoid nanosheets for molecular recognition. ACS Nano 7:9276-9286. http://dx.doi.org/10.1021/nn403899y.
-
(2013)
ACS Nano
, vol.7
, pp. 9276-9286
-
-
Olivier, G.K.1
Cho, A.2
Sanii, B.3
Connolly, M.D.4
Tran, H.5
Zuckermann, R.N.6
-
12
-
-
84935924644
-
Functionalized peptoid nano-sheets
-
American Chemical Society, Washington, DC
-
Olivier G, Proulx C, Zuckermann R. 2013. Functionalized peptoid nano-sheets. Abstracts of papers of the American Chemical Society, vol 246. American Chemical Society, Washington, DC.
-
(2013)
Abstracts of Papers of the American Chemical Society
, vol.246
-
-
Olivier, G.1
Proulx, C.2
Zuckermann, R.3
-
13
-
-
34247153326
-
Role of peptide hydrophobicity in the mechanism of action of alphahelical antimicrobial peptides
-
Chen YX, Guarnieri MT, Vasil AI, Vasil ML, Mant CT, Hodges RS. 2007. Role of peptide hydrophobicity in the mechanism of action of alphahelical antimicrobial peptides. Antimicrob Agents Chemother 51:1398-1406. http://dx.doi.org/10.1128/AAC.00925-06.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 1398-1406
-
-
Chen, Y.X.1
Guarnieri, M.T.2
Vasil, A.I.3
Vasil, M.L.4
Mant, C.T.5
Hodges, R.S.6
-
14
-
-
84877702474
-
Role of amphiphilicity in the design of synthetic mimics of antimicrobial peptides with Gram-negative activity
-
Thaker HD, Cankaya A, Scott RW, Tew GN. 2013. Role of amphiphilicity in the design of synthetic mimics of antimicrobial peptides with Gram-negative activity. ACS Med Chem Lett 4:481-485. http://dx.doi.org /10.1021/ml300307b.
-
(2013)
ACS Med Chem Lett
, vol.4
, pp. 481-485
-
-
Thaker, H.D.1
Cankaya, A.2
Scott, R.W.3
Tew, G.N.4
-
15
-
-
1842587737
-
Design of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12)
-
Park Y, Kim HN, Park SN, Jang SH, Choi CH, Lim HT, Hahm KS. 2004. Design of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12). Biotechnol Lett 26:493-498. http://dx.doi.org/10.1023/B:BILE.0000019556.79703.4b.
-
(2004)
Biotechnol Lett
, vol.26
, pp. 493-498
-
-
Park, Y.1
Kim, H.N.2
Park, S.N.3
Jang, S.H.4
Choi, C.H.5
Lim, H.T.6
Hahm, K.S.7
-
16
-
-
0027043261
-
Design of model amphipathic peptides having potent antimicrobial activities
-
Blondelle SE, Houghten RA. 1992. Design of model amphipathic peptides having potent antimicrobial activities. Biochemistry 31:12688-12694. http://dx.doi.org/10.1021/bi00165a020.
-
(1992)
Biochemistry
, vol.31
, pp. 12688-12694
-
-
Blondelle, S.E.1
Houghten, R.A.2
-
17
-
-
14544282377
-
Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
-
Brogden KA. 2005. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 3:238-250. http://dx.doi.org/10.1038/nrmicro1098.
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 238-250
-
-
Brogden, K.A.1
-
18
-
-
0141888597
-
Helical peptoid mimics of magainin-2 amide
-
Patch JA, Barron AE. 2003. Helical peptoid mimics of magainin-2 amide. J Am Chem Soc 125:12092-12093. http://dx.doi.org/10.1021/ja037320d.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 12092-12093
-
-
Patch, J.A.1
Barron, A.E.2
-
19
-
-
64549125571
-
Identification of novel antibacterial peptides by chemoinformatics and machine learning
-
Fjell CD, Jenssen H, Hilpert K, Cheung WA, Pante N, Hancock REW, Cherkasov A. 2009. Identification of novel antibacterial peptides by chemoinformatics and machine learning. J Med Chem 52:2006-2015. http: //dx.doi.org/10.1021/jm8015365.
-
(2009)
J Med Chem
, vol.52
, pp. 2006-2015
-
-
Fjell, C.D.1
Jenssen, H.2
Hilpert, K.3
Cheung, W.A.4
Pante, N.5
Hancock, R.E.W.6
Cherkasov, A.7
-
20
-
-
0029896177
-
Synthesis of N-substituted glycine peptoid libraries
-
Figliozzi GM, Goldsmith R, Ng SC, Banville SC, Zuckermann RN. 1996. Synthesis of N-substituted glycine peptoid libraries. Methods Enzymol 267:437-447. http://dx.doi.org/10.1016/S0076-6879(96)67027-X.
-
(1996)
Methods Enzymol
, vol.267
, pp. 437-447
-
-
Figliozzi, G.M.1
Goldsmith, R.2
Ng, S.C.3
Banville, S.C.4
Zuckermann, R.N.5
-
21
-
-
39449086721
-
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
-
Wiegand I, Hilpert K, Hancock RE. 2008. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc 3:163-175. http://dx.doi.org/10.1038/nprot.2007.521.
-
(2008)
Nat Protoc
, vol.3
, pp. 163-175
-
-
Wiegand, I.1
Hilpert, K.2
Hancock, R.E.3
-
22
-
-
78650156321
-
Optimization of antibacterial peptides by genetic algorithms and chemin-formatics
-
Fjell CD, Jenssen H, Cheung WA, Hancock RE, Cherkasov A. 2011. Optimization of antibacterial peptides by genetic algorithms and chemin-formatics. Chem Biol Drug Des 77:48-56. http://dx.doi.org/10.1111/j.1747-0285.2010.01044.x.
-
(2011)
Chem Biol Drug Des
, vol.77
, pp. 48-56
-
-
Fjell, C.D.1
Jenssen, H.2
Cheung, W.A.3
Hancock, R.E.4
Cherkasov, A.5
-
23
-
-
60749130267
-
Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs
-
Cherkasov A, Hilpert K, Jenssen H, Fjell CD, Waldbrook M, Mullaly SC, Volkmer R, Hancock REW. 2009. Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs. ACS Chem Biol 4:65-74. http://dx.doi.org/10.1021/cb800240j.
-
(2009)
ACS Chem Biol
, vol.4
, pp. 65-74
-
-
Cherkasov, A.1
Hilpert, K.2
Jenssen, H.3
Fjell, C.D.4
Waldbrook, M.5
Mullaly, S.C.6
Volkmer, R.7
Hancock, R.E.W.8
-
24
-
-
28044446984
-
Novel lysine-peptoid hybrids with antibacterial properties
-
Ryge TS, Hansen PR. 2005. Novel lysine-peptoid hybrids with antibacterial properties. J Pept Sci 11:727-734. http://dx.doi.org/10.1002/psc.705.
-
(2005)
J Pept Sci
, vol.11
, pp. 727-734
-
-
Ryge, T.S.1
Hansen, P.R.2
-
25
-
-
84877287392
-
Effect of repetitive lysine-tryptophan motifs on the bactericidal activity of antimicrobial peptides
-
Gopal R, Seo CH, Song PI, Park Y. 2013. Effect of repetitive lysine-tryptophan motifs on the bactericidal activity of antimicrobial peptides. Amino Acids 44:645-660. http://dx.doi.org/10.1007/s00726-012-1388-6.
-
(2013)
Amino Acids
, vol.44
, pp. 645-660
-
-
Gopal, R.1
Seo, C.H.2
Song, P.I.3
Park, Y.4
-
26
-
-
67849115958
-
Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5
-
de Leeuw E, Rajabi M, Zou G, Pazgier M, Lu W. 2009. Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5. FEBS Lett 583:2507-2512. http://dx.doi.org/10.1016/j.febslet.2009.06.051.
-
(2009)
FEBS Lett
, vol.583
, pp. 2507-2512
-
-
De Leeuw, E.1
Rajabi, M.2
Zou, G.3
Pazgier, M.4
Lu, W.5
-
27
-
-
0344519712
-
The pharmacophore of short cationic antibacterial peptides
-
Strøm MB, Haug BE, Skar ML, Stensen W, Stiberg T, Svendsen JS. 2003. The pharmacophore of short cationic antibacterial peptides. J Med Chem 46:1567-1570. http://dx.doi.org/10.1021/jm0340039.
-
(2003)
J Med Chem
, vol.46
, pp. 1567-1570
-
-
Strøm, M.B.1
Haug, B.E.2
Skar, M.L.3
Stensen, W.4
Stiberg, T.5
Svendsen, J.S.6
-
28
-
-
17044394805
-
Design of host defence peptides for antimicrobial and immunity enhancing activities
-
McPhee JB, Scott MG, Hancock RE. 2005. Design of host defence peptides for antimicrobial and immunity enhancing activities. Comb Chem High Throughput Screen 8:257-272. http://dx.doi.org/10.2174 /1386207053764558.
-
(2005)
Comb Chem High Throughput Screen
, vol.8
, pp. 257-272
-
-
McPhee, J.B.1
Scott, M.G.2
Hancock, R.E.3
-
29
-
-
33748933561
-
Alpha-helical antimicrobial peptides - Using a sequence template to guide structure-activity relationship studies
-
Zelezetsky I, Tossi A. 2006. Alpha-helical antimicrobial peptides - using a sequence template to guide structure-activity relationship studies. Biochim Biophys Acta 1758:1436-1449. http://dx.doi.org/10.1016/j.bbamem.2006.03.021.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 1436-1449
-
-
Zelezetsky, I.1
Tossi, A.2
-
30
-
-
0030664760
-
Modulation of membrane activity of amphipathic, antibacterial peptides by slight modifications of the hydrophobic moment
-
Wieprecht T, Dathe M, Krause E, Beyermann M, Maloy WL, Mac-Donald DL, Bienert M. 1997. Modulation of membrane activity of amphipathic, antibacterial peptides by slight modifications of the hydrophobic moment. FEBS Lett 417:135-140. http://dx.doi.org/10.1016 /S0014-5793(97)01266-0.
-
(1997)
FEBS Lett
, vol.417
, pp. 135-140
-
-
Wieprecht, T.1
Dathe, M.2
Krause, E.3
Beyermann, M.4
Maloy, W.L.5
MacDonald, D.L.6
Bienert, M.7
-
31
-
-
34250195381
-
Folding amphipathic helices into membranes: Amphiphilicity trumps hydrophobicity
-
Fernández-Vidal M, Jayasinghe S, Ladokhin AS, White SH. 2007. Folding amphipathic helices into membranes: amphiphilicity trumps hydrophobicity. J Mol Biol 370:459-470. http://dx.doi.org/10.1016/j.jmb.2007.05.016.
-
(2007)
J Mol Biol
, vol.370
, pp. 459-470
-
-
Fernández-Vidal, M.1
Jayasinghe, S.2
Ladokhin, A.S.3
White, S.H.4
-
32
-
-
84886312536
-
In silico models for designing and discovering novel anticancer peptides
-
Tyagi A, Kapoor P, Kumar R, Chaudhary K, Gautam A, Raghava GP. 2013. In silico models for designing and discovering novel anticancer peptides. Sci Rep 3:2984. http://dx.doi.org/10.1038/srep02984.
-
(2013)
Sci Rep
, vol.3
, pp. 2984
-
-
Tyagi, A.1
Kapoor, P.2
Kumar, R.3
Chaudhary, K.4
Gautam, A.5
Raghava, G.P.6
-
33
-
-
77958085274
-
Describing the mechanism of antimicrobial peptide action with the interfacial activity model
-
Wimley WC. 2010. Describing the mechanism of antimicrobial peptide action with the interfacial activity model. ACS Chem Biol 5:905-917. http: //dx.doi.org/10.1021/cb1001558.
-
(2010)
ACS Chem Biol
, vol.5
, pp. 905-917
-
-
Wimley, W.C.1
-
34
-
-
84857989917
-
Charge distribution and imperfect amphipathicity affect pore formation by antimicrobial peptides
-
Mihajlovic M, Lazaridis T. 2012. Charge distribution and imperfect amphipathicity affect pore formation by antimicrobial peptides. Biochim Biophys Acta 1818:1274-1283. http://dx.doi.org/10.1016/j.bbamem.2012.01.016.
-
(2012)
Biochim Biophys Acta
, vol.1818
, pp. 1274-1283
-
-
Mihajlovic, M.1
Lazaridis, T.2
-
35
-
-
16844373772
-
Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index
-
Chen Y, Mant CT, Farmer SW, Hancock RE, Vasil ML, Hodges RS. 2005. Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem 280: 12316-12329. http://dx.doi.org/10.1074/jbc.M413406200.
-
(2005)
J Biol Chem
, vol.280
, pp. 12316-12329
-
-
Chen, Y.1
Mant, C.T.2
Farmer, S.W.3
Hancock, R.E.4
Vasil, M.L.5
Hodges, R.S.6
-
36
-
-
0024388798
-
Ciprofloxacin and the fluoroquinolones. New concepts on the mechanism of action and resistance
-
Fisher LM, Lawrence JM, Josty IC, Hopewell R, Margerrison EEC, Cullen ME. 1989. Ciprofloxacin and the fluoroquinolones. New concepts on the mechanism of action and resistance. Am J Med 87:S2-S8. http://dx.doi.org/10.1016/0002-9343(89)90010-7.
-
(1989)
Am J Med
, vol.87
, pp. S2-S8
-
-
Fisher, L.M.1
Lawrence, J.M.2
Josty, I.C.3
Hopewell, R.4
Margerrison, E.E.C.5
Cullen, M.E.6
-
37
-
-
33748988741
-
Tryptophan- and arginine-rich antimicrobial peptides: Structures and mechanisms of action
-
Chan DI, Prenner EJ, Vogel HJ. 2006. Tryptophan- and arginine-rich antimicrobial peptides: structures and mechanisms of action. Biochim Biophys Acta 1758:1184-1202. http://dx.doi.org/10.1016/j.bbamem.2006.04.006.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 1184-1202
-
-
Chan, D.I.1
Prenner, E.J.2
Vogel, H.J.3
-
38
-
-
84898432553
-
Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli
-
Jahnsen RD, Sandberg-Schaal A, Vissing KJ, Nielsen HM, Frimodt-Møller N, Franzyk H. 2014. Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. J Med Chem 57:2864-2873. http://dx.doi.org/10.1021/jm401335p.
-
(2014)
J Med Chem
, vol.57
, pp. 2864-2873
-
-
Jahnsen, R.D.1
Sandberg-Schaal, A.2
Vissing, K.J.3
Nielsen, H.M.4
Frimodt-Møller, N.5
Franzyk, H.6
|