Modulation of membrane activity of amphipathic, antibacterial peptides by slight modifications of the hydrophobic moment

FEBS Letters

Volumn 417, Issue 1, 1997, Pages 135-140

  Wieprecht, Torsten ^a   Dathe, Margitta ^a   Krause, Eberhard ^a   Beyermann, Michael ^a   Maloy, W Lee ^b   MacDonald, Dorothy L ^b   Bienert, Michael ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b Genaera Corporation   (United States)

Author keywords

Amphipathic helix; Antibacterial peptide; Antimicrobial peptide; Hydrophobic moment; Magainin

Indexed keywords

ANTIINFECTIVE AGENT; MAGAININ 2; PEPTIDE;

ANTIMICROBIAL ACTIVITY; ARTICLE; CIRCULAR DICHROISM; HEMOLYSIS; HYDROPHOBICITY; MEMBRANE BINDING; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; HUMANS; LIPID METABOLISM; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS PROTEINS;

EID: 0030664760     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01266-0     Document Type: Article

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