The pharmacophore of short cationic antibacterial peptides

Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2003, Pages 1567-1570

  Strøm, Morten B ^a   Haug, Bengt Erik ^a   Skar, Merete L ^a   Stensen, Wenche ^a   Stiberg, Trine ^a   Svendsen, John S ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLYLACETAMIDE DERIVATIVE; ARGINYLTRYPTOPHYL BENZYL ESTER DERIVATIVE; ARGINYLTRYPTOPHYL METHYL ESTER DERIVATIVE; CYCLOHEXYLAMINE DERIVATIVE; CYCLOHEXYLCARBOXAMIDE DERIVATIVE; IB 367; INDOLEACETIC ACID DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; CATION TRANSPORT; CHEMOTAXONOMY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG METABOLISM; DRUG STABILITY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOGENICITY; LIPOPHILICITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR SIZE; MULTIDRUG RESISTANCE; PEPTIDE ANALYSIS; PHARMACOPHORE; PHASE 3 CLINICAL TRIAL; PROTEIN MOTIF; STAPHYLOCOCCUS AUREUS; SYSTEMIC CIRCULATION;

ANTIMICROBIAL CATIONIC PEPTIDES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; HEMOLYSIS; HUMANS; MICROBIAL SENSITIVITY TESTS; PEPTIDE FRAGMENTS; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0344519712     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0340039     Document Type: Article

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