Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr-/- mice

FEBS Journal

Volumn 282, Issue 12, 2015, Pages 2327-2338

  Hendrikx, Tim ^a   Jeurissen, Mike L J ^a,b   Van Gorp, Patrick J ^a   Gijbels, Marion J ^a   Walenbergh, Sofie M A ^a   Houben, Tom ^a,b   Van Gorp, Rick ^a   Pöttgens, Chantal C ^a   Stienstra, Rinke ^c   Netea, Mihai G ^c,d   Hofker, Marten H ^e   Donners, Marjo M P C ^a   Shiri Sverdlov, Ronit ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d WAGENINGEN UNIVERSITY   (Netherlands)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

atherosclerosis; cardiovascular diseases; caspase 1 11; inflammasome; macrophage

Indexed keywords

CASPASE 11; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; CASP11 PROTEIN, MOUSE; CASPASE; CHOLESTEROL INTAKE; CYTOKINE; LOW DENSITY LIPOPROTEIN RECEPTOR; LY ANTIGEN; LY-6C ANTIGEN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BONE MARROW; CHOLESTEROL DIET; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEFICIENCY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HISTOLOGY; LEUKOCYTE; LIPID DIET; LOW DENSITY LIPOPROTEIN RECEPTOR KO MOUSE; MONOCYTE; MORPHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; WESTERN BLOTTING; WILD TYPE; ADVERSE EFFECTS; ANIMAL; APOPTOSIS; BLOOD; BONE MARROW CELL; C57BL MOUSE; CHOLESTEROL INTAKE; COMPARATIVE STUDY; DISEASE COURSE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; NECROSIS; PATHOLOGY; THORACIC AORTA;

MUS;

ANIMALS; ANTIGENS, LY; AORTA, THORACIC; APOPTOSIS; ATHEROSCLEROSIS; BONE MARROW CELLS; CASPASE 1; CASPASES; CHOLESTEROL, DIETARY; CYTOKINES; DIET, HIGH-FAT; DISEASE PROGRESSION; FEMALE; LEUKOCYTES; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; NECROSIS; RECEPTORS, LDL;

EID: 84935891614     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13279     Document Type: Article

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