Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation

Nature Communications

Volumn 6, Issue , 2015, Pages

  Whalley, Helen J ^a   Porter, Andrew P ^a   Diamantopoulou, Zoi ^a   White, Gavin R M ^a   Castañeda Saucedo, Eduardo ^a   Malliri, Angeliki ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; KINESIN 5; MONASTROL; P21 ACTIVATED KINASE 1; P21 ACTIVATED KINASE 2; PROTEIN TIAM1; RAC PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CDK1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; KIF11 PROTEIN, HUMAN; KINESIN; TIAM1 PROTEIN, MOUSE;

CANCER; CHROMOSOME; DISEASE TREATMENT; ENZYME ACTIVITY; GERM CELL; INHIBITION; INHIBITOR; MAMMAL; PHOSPHATE;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CENTROSOME; CHROMOSOME SEGREGATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PROMETAPHASE; PROPHASE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; DOG; HEK293 CELL LINE; MDCK CELL LINE; METABOLISM; MOUSE; PHOSPHORYLATION; SPINDLE APPARATUS;

MAMMALIA;

ANIMALS; CDC2 PROTEIN KINASE; CENTROSOME; CYCLIN-DEPENDENT KINASES; DOGS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HUMANS; KINESIN; MADIN DARBY CANINE KIDNEY CELLS; MICE; PHOSPHORYLATION; RAC GTP-BINDING PROTEINS; SPINDLE APPARATUS;

EID: 84935888782     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8437     Document Type: Article

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