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Volumn 287, Issue 48, 2012, Pages 40560-40569

Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETONS; IN-VITRO; IN-VIVO; KINESINS; MAMMALIAN CELLS; MICROTUBULES; P-21 ACTIVATED KINASE;

EID: 84870039354     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.399576     Document Type: Article
Times cited : (22)

References (40)
  • 1
    • 34547726131 scopus 로고    scopus 로고
    • The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells
    • DOI 10.1091/mbc.E07-02-0110
    • Manning, A. L., Ganem, N. J., Bakhoum, S. F., Wagenbach, M., Wordeman, L., and Compton, D. A. (2007) The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Mol. Biol. Cell 18, 2970-2979 (Pubitemid 47235304)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.8 , pp. 2970-2979
    • Manning, A.L.1    Ganem, N.J.2    Bakhoum, S.F.3    Wagenbach, M.4    Wordeman, L.5    Compton, D.A.6
  • 2
    • 0035860717 scopus 로고    scopus 로고
    • Molecular dissection of the microtubule depolymerizing activity of mitotic centromereassociated kinesin
    • Maney, T., Wagenbach, M., and Wordeman, L. (2001) Molecular dissection of the microtubule depolymerizing activity of mitotic centromereassociated kinesin. J. Biol. Chem. 276, 34753-34758
    • (2001) J. Biol. Chem. , vol.276 , pp. 34753-34758
    • Maney, T.1    Wagenbach, M.2    Wordeman, L.3
  • 3
    • 0031873388 scopus 로고    scopus 로고
    • Mitotic centromere-associated kinesin is important for anaphase chromosome segregation
    • DOI 10.1083/jcb.142.3.787
    • Maney, T., Hunter, A. W., Wagenbach, M., and Wordeman, L. (1998) Mitotic centromere-associated kinesin is important for anaphase chromosome segregation. J. Cell Biol. 142, 787-801 (Pubitemid 28381495)
    • (1998) Journal of Cell Biology , vol.142 , Issue.3 , pp. 787-801
    • Maney, T.1    Hunter, A.W.2    Wagenbach, M.3    Wordeman, L.4
  • 4
    • 0028887847 scopus 로고
    • Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis
    • Wordeman, L., and Mitchison, T. J. (1995) Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. J. Cell Biol. 128, 95-104
    • (1995) J. Cell Biol. , vol.128 , pp. 95-104
    • Wordeman, L.1    Mitchison, T.J.2
  • 5
    • 50849131840 scopus 로고    scopus 로고
    • Aurora-A phosphorylates MCAK to control ran-dependent spindle bipolarity
    • Zhang, X., Ems-McClung, S. C., and Walczak, C. E. (2008) Aurora-A phosphorylates MCAK to control ran-dependent spindle bipolarity. Mol. Biol. Cell 19, 2752-2765
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2752-2765
    • Zhang, X.1    Ems-McClung, S.C.2    Walczak, C.E.3
  • 6
    • 34548481992 scopus 로고    scopus 로고
    • Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function
    • DOI 10.1091/mbc.E07-01-0086
    • Zhang, X., Lan, W., Ems-McClung, S. C., Stukenberg, P. T., and Walczak, C. E. (2007) Aurora B phosphorylates multiple sites on mitotic centromere- associated kinesin to spatially and temporally regulate its function. Mol. Biol. Cell 18, 3264-3276 (Pubitemid 47378669)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.9 , pp. 3264-3276
    • Zhang, X.1    Lan, W.2    Ems-McClung, S.C.3    Stukenberg, P.T.4    Walczak, C.E.5
  • 8
  • 9
    • 38549168381 scopus 로고    scopus 로고
    • Centromeric Aurora-B activation requires TD-60, microtubules, and substrate priming phosphorylation
    • DOI 10.1126/science.1148980
    • Rosasco-Nitcher, S. E., Lan, W., Khorasanizadeh, S., and Stukenberg, P. T. (2008) Centromeric Aurora-B activation requires TD-60, microtubules, and substrate priming phosphorylation. Science 319, 469-472 (Pubitemid 351160581)
    • (2008) Science , vol.319 , Issue.5862 , pp. 469-472
    • Rosasco-Nitcher, S.E.1    Lan, W.2    Khorasanizadeh, S.3    Stukenberg, P.T.4
  • 11
    • 34249655122 scopus 로고    scopus 로고
    • Nonredundant Functions of Kinesin-13s during Meiotic Spindle Assembly
    • DOI 10.1016/j.cub.2007.04.057, PII S0960982207013371
    • Ohi, R., Burbank, K., Liu, Q., and Mitchison, T. J. (2007) Nonredundant functions of Kinesin-13s during meiotic spindle assembly. Curr. Biol. 17, 953-959 (Pubitemid 46829840)
    • (2007) Current Biology , vol.17 , Issue.11 , pp. 953-959
    • Ohi, R.1    Burbank, K.2    Liu, Q.3    Mitchison, T.J.4
  • 12
    • 1542290607 scopus 로고    scopus 로고
    • Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity
    • DOI 10.1016/S0960-9822(04)00064-8, PII S0960982204000648
    • Lan, W., Zhang, X., Kline-Smith, S. L., Rosasco, S. E., Barrett-Wilt, G. A., Shabanowitz, J., Hunt, D. F., Walczak, C. E., and Stukenberg, P. T. (2004) Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr. Biol. 14, 273-286 (Pubitemid 38300205)
    • (2004) Current Biology , vol.14 , Issue.4 , pp. 273-286
    • Lan, W.1    Zhang, X.2    Kline-Smith, S.L.3    Rosasco, S.E.4    Barrett-Wilt, G.A.5    Shabanowitz, J.6    Hunt, D.F.7    Walczak, C.E.8    Stukenberg, P.T.9
  • 13
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch, G. M. (2003) Biology of the p21-activated kinases. Annu. Rev. Biochem. 72, 743-781
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 743-781
    • Bokoch, G.M.1
  • 15
    • 3042847368 scopus 로고    scopus 로고
    • Rac-induced increase of phosphorylation of myosin regulatory light chain in HeLa cells
    • DOI 10.1002/cm.20009
    • Brzeska, H., Szczepanowska, J., Matsumura, F., and Korn, E. D. (2004) Rac-induced increase of phosphorylation of myosin regulatory light chain in HeLa cells. Cell Motil. Cytoskeleton 58, 186-199 (Pubitemid 38849956)
    • (2004) Cell Motility and the Cytoskeleton , vol.58 , Issue.3 , pp. 186-199
    • Brzeska, H.1    Szczepanowska, J.2    Matsumura, F.3    Korn, E.D.4
  • 16
    • 16344390935 scopus 로고    scopus 로고
    • A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC
    • DOI 10.1523/JNEUROSCI.3553-04.2005
    • Zhang, H., Webb, D. J., Asmussen, H., Niu, S., and Horwitz, A. F. (2005) A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. J. Neurosci. 25, 3379-3388 (Pubitemid 40471346)
    • (2005) Journal of Neuroscience , vol.25 , Issue.13 , pp. 3379-3388
    • Zhang, H.1    Webb, D.J.2    Asmussen, H.3    Niu, S.4    Horwitz, A.F.5
  • 17
    • 1242271991 scopus 로고    scopus 로고
    • Regulation of Microtubule Destabilizing Activity of Op18/Stathmin Downstream of Rac1
    • DOI 10.1074/jbc.M307261200
    • Wittmann, T., Bokoch, G. M., and Waterman-Storer, C. M. (2004) Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1. J. Biol. Chem. 279, 6196-6203 (Pubitemid 38220653)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 6196-6203
    • Wittmann, T.1    Bokoch, G.M.2    Waterman-Storer, C.M.3
  • 19
    • 1642446043 scopus 로고    scopus 로고
    • p-41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate
    • DOI 10.1038/sj.embor.7400079
    • Vadlamudi, R. K., Li, F., Barnes, C. J., Bagheri-Yarmand, R., and Kumar, R. (2004) p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate. EMBO Rep. 5, 154-160 (Pubitemid 38401194)
    • (2004) EMBO Reports , vol.5 , Issue.2 , pp. 154-160
    • Vadlamudi, R.K.1    Li, F.2    Barnes, C.J.3    Bagheri-Yarmand, R.4    Kumar, R.5
  • 20
    • 26944442735 scopus 로고    scopus 로고
    • The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
    • DOI 10.1016/j.molcel.2005.08.035, PII S1097276505016011
    • Zhao, Z. S., Lim, J. P., Ng, Y. W., Lim, L., and Manser, E. (2005) The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol. Cell 20, 237-249 (Pubitemid 41484169)
    • (2005) Molecular Cell , vol.20 , Issue.2 , pp. 237-249
    • Zhao, Z.-S.1    Lim, J.P.2    Ng, Y.-W.3    Lim, L.4    Manser, E.5
  • 21
    • 84863008444 scopus 로고    scopus 로고
    • Mitotic centromere-associated kinesin (MCAK): A potential cancer drug target
    • Sanhaji, M., Friel, C. T., Wordeman, L., Louwen, F., and Yuan, J. (2011) Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target. Oncotarget 2, 935-947
    • (2011) Oncotarget , vol.2 , pp. 935-947
    • Sanhaji, M.1    Friel, C.T.2    Wordeman, L.3    Louwen, F.4    Yuan, J.5
  • 23
    • 84861949049 scopus 로고    scopus 로고
    • MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochores attachment
    • Domnitz, S. B., Wagenbach, M., Decarreau, J., and Wordeman, L. (2012) MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochores attachment. J. Cell Biol. 197, 231-237
    • (2012) J. Cell Biol. , vol.197 , pp. 231-237
    • Domnitz, S.B.1    Wagenbach, M.2    Decarreau, J.3    Wordeman, L.4
  • 24
    • 0034671927 scopus 로고    scopus 로고
    • Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-β1-mediated angiogenesis
    • DOI 10.1074/jbc.M006150200
    • Bagheri-Yarmand, R., Vadlamudi, R. K., Wang, R. A., Mendelsohn, J., and Kumar, R. (2000) Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-β1-mediated angiogenesis. J. Biol. Chem. 275, 39451-39457 (Pubitemid 32058970)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39451-39457
    • Bagheri-Yarmand, R.1    Vadlamudi, R.K.2    Wang, R.-A.3    Mendelsohn, J.4    Kumar, R.5
  • 26
    • 0036668638 scopus 로고    scopus 로고
    • p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells
    • DOI 10.1093/embo-reports/kvf157
    • Li, F., Adam, L., Vadlamudi, R. K., Zhou, H., Sen, S., Chernoff, J., Mandal, M., and Kumar, R. (2002) p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells. EMBO Rep. 3, 767-773 (Pubitemid 34966016)
    • (2002) EMBO Reports , vol.3 , Issue.8 , pp. 767-773
    • Li, F.1    Adam, L.2    Vadlamudi, R.K.3    Zhou, H.4    Sen, S.5    Chernoff, J.6    Mandal, M.7    Kumar, R.8
  • 27
    • 0034680834 scopus 로고    scopus 로고
    • Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells
    • Vadlamudi, R. K., Adam, L., Wang, R. A., Mandal, M., Nguyen, D., Sahin, A., Chernoff, J., Hung, M. C., and Kumar, R. (2000) Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J. Biol. Chem. 275, 36238-36244
    • (2000) J. Biol. Chem. , vol.275 , pp. 36238-36244
    • Vadlamudi, R.K.1    Adam, L.2    Wang, R.A.3    Mandal, M.4    Nguyen, D.5    Sahin, A.6    Chernoff, J.7    Hung, M.C.8    Kumar, R.9
  • 29
    • 18444407796 scopus 로고    scopus 로고
    • Mammalian mitotic centromere-associated kinesin (MCAK): A new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents
    • DOI 10.1111/j.1742-4658.2005.04600.x
    • Aoki, S., Ohta, K., Yamazaki, T., Sugawara, F., and Sakaguchi, K. (2005) Mammalian mitotic centromere-associated kinesin (MCAK): a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents. FEBS J. 272, 2132-2140 (Pubitemid 40646783)
    • (2005) FEBS Journal , vol.272 , Issue.9 , pp. 2132-2140
    • Aoki, S.1    Ohta, K.2    Yamazaki, T.3    Sugawara, F.4    Sakaguchi, K.5
  • 30
    • 0033130049 scopus 로고    scopus 로고
    • Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts
    • Waterman-Storer, C. M., Worthylake, R. A., Liu, B. P., Burridge, K., and Salmon, E. D. (1999) Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts. Nat. Cell Biol. 1, 45-50 (Pubitemid 129495009)
    • (1999) Nature Cell Biology , vol.1 , Issue.1 , pp. 45-50
    • Waterman-Storer, C.M.1    Worthylake, R.A.2    Liu, B.P.3    Burridget, K.4    Salmon, E.D.5
  • 31
    • 0035842895 scopus 로고    scopus 로고
    • A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization
    • DOI 10.1083/jcb.200104123
    • Cau, J., Faure, S., Comps, M., Delsert, C., and Morin, N. (2001) A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization. J. Cell Biol. 155, 1029-1042 (Pubitemid 34286253)
    • (2001) Journal of Cell Biology , vol.155 , Issue.6 , pp. 1029-1042
    • Cau, J.1    Faure, S.2    Comps, M.3    Delsert, C.4    Morin, N.5
  • 32
    • 84856196744 scopus 로고    scopus 로고
    • K-fibre minus ends are stabilized by a RanGTP-dependent mechanism essential for functional spindle assembly
    • Meunier, S., and Vernos, I. (2011) K-fibre minus ends are stabilized by a RanGTP-dependent mechanism essential for functional spindle assembly. Nat. Cell Biol. 13, 1406-1414
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1406-1414
    • Meunier, S.1    Vernos, I.2
  • 33
    • 8844284560 scopus 로고    scopus 로고
    • GPS: A novel group-based phosphorylation predicting and scoring method
    • DOI 10.1016/j.bbrc.2004.11.001, PII S0006291X04025288
    • Zhou, F. F., Xue, Y., Chen, G. L., and Yao, X. (2004) GPS: a novel group-based phosphorylation predicting and scoring method. Biochem. Biophys. Res. Commun. 325, 1443-1448 (Pubitemid 39535923)
    • (2004) Biochemical and Biophysical Research Communications , vol.325 , Issue.4 , pp. 1443-1448
    • Zhou, F.-F.1    Xue, Y.2    Chen, G.-L.3    Yao, X.4
  • 34
    • 0037013227 scopus 로고    scopus 로고
    • Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway
    • DOI 10.1074/jbc.M111627200
    • Charvet, C., Auberger, P., Tartare-Deckert, S., Bernard, A., and Deckert, M. (2002) Vav1couples T cell receptor to serum responsible factor-dependent transcription via a MEK dependent pathway. J. Biol. Chem. 277, 15376-15384 (Pubitemid 34967799)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.18 , pp. 15376-15384
    • Charvet, C.1    Auberger, P.2    Tartare-Deckert, S.3    Bernard, A.4    Deckert, M.5
  • 36
    • 84992268369 scopus 로고    scopus 로고
    • Regulation of localization and activity of the microtubule depolymerase MCAK
    • Tanenbaum, M. E., Medema, R. H., and Akhmanova, A. (2011) Regulation of localization and activity of the microtubule depolymerase MCAK. Bioarchitecture 1, 80-87
    • (2011) Bioarchitecture , vol.1 , pp. 80-87
    • Tanenbaum, M.E.1    Medema, R.H.2    Akhmanova, A.3
  • 37
    • 50849139592 scopus 로고    scopus 로고
    • Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells
    • Katayama, H., Sasai, K., Kloc, M., Brinkley, B. R., and Sen, S. (2008) Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells. Cell Cycle 7, 2691-2704
    • (2008) Cell Cycle , vol.7 , pp. 2691-2704
    • Katayama, H.1    Sasai, K.2    Kloc, M.3    Brinkley, B.R.4    Sen, S.5
  • 38
    • 0037084163 scopus 로고    scopus 로고
    • -/- cells
    • DOI 10.1093/emboj/21.4.483
    • Meraldi, P., Honda, R., and Nigg, E. A. (2002) Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J. 21, 483-492 (Pubitemid 34174030)
    • (2002) EMBO Journal , vol.21 , Issue.4 , pp. 483-492
    • Meraldi, P.1    Honda, R.2    Nigg, E.A.3
  • 39
    • 0028978955 scopus 로고
    • γ-Tubulin can both nucleate microtubule assembly and self-assemble into novel tubular structures in mammalian cells
    • Shu, H. B., and Joshi, H. C. (1995) γ-Tubulin can both nucleate microtubule assembly and self-assemble into novel tubular structures in mammalian cells. J. Cell Biol. 130, 1137-1147
    • (1995) J. Cell Biol. , vol.130 , pp. 1137-1147
    • Shu, H.B.1    Joshi, H.C.2
  • 40
    • 0033229726 scopus 로고    scopus 로고
    • Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization
    • Purohit, A., Tynan, S. H., Vallee, R., and Doxsey, S. J. (1999) Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization. J. Cell Biol. 147, 481-492
    • (1999) J. Cell Biol. , vol.147 , pp. 481-492
    • Purohit, A.1    Tynan, S.H.2    Vallee, R.3    Doxsey, S.J.4


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