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Volumn 128, Issue 13, 2015, Pages 2244-2258

Regulation of epithelial cell polarity by PAR-3 depends on Girdin transcription and Girdin-Gαi3 signaling

Author keywords

AP 2; Apicobasal polarity; Girdin; G i3; PAR aPKC complex; Transcription

Indexed keywords

GIRDIN PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 3; SHORT HAIRPIN RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CARRIER PROTEIN; CCDC88A PROTEIN, HUMAN; GNAI3 PROTEIN, HUMAN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PAR-3 PROTEIN, RAT; PKC-3 PROTEIN; PROTEIN BINDING; PROTEIN KINASE C; VESICULAR TRANSPORT PROTEIN;

EID: 84935515727     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.160879     Document Type: Article
Times cited : (32)

References (83)
  • 3
    • 77951224719 scopus 로고    scopus 로고
    • Morphogenesis of epithelial tubes: insights into tube formation, elongation, and elaboration
    • Andrew, D. J. and Ewald, A. J. (2010). Morphogenesis of epithelial tubes: insights into tube formation, elongation, and elaboration. Dev. Biol. 341, 34-55.
    • (2010) Dev. Biol. , vol.341 , pp. 34-55
    • Andrew, D.J.1    Ewald, A.J.2
  • 4
    • 27544450869 scopus 로고    scopus 로고
    • Heterotrimeric G proteins and regulation of size asymmetry during cell division
    • Bellaiche, Y. and Gotta, M. (2005). Heterotrimeric G proteins and regulation of size asymmetry during cell division. Curr. Opin. Cell Biol. 17, 658-663.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 658-663
    • Bellaiche, Y.1    Gotta, M.2
  • 5
    • 0037228253 scopus 로고    scopus 로고
    • Integrated activity of PDZ protein complexes regulates epithelial polarity
    • Bilder, D., Schober, M. and Perrimon, N. (2003). Integrated activity of PDZ protein complexes regulates epithelial polarity. Nat. Cell Biol. 5, 53-58.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 53-58
    • Bilder, D.1    Schober, M.2    Perrimon, N.3
  • 6
    • 0028872554 scopus 로고
    • The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma
    • Bosher, J. M., Williams, T. and Hurst, H. C. (1995). The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma. Proc. Natl. Acad. Sci. USA 92, 744-747.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 744-747
    • Bosher, J.M.1    Williams, T.2    Hurst, H.C.3
  • 7
    • 0038386022 scopus 로고    scopus 로고
    • Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2
    • Braganca, J., Eloranta, J. J., Bamforth, S. D., Ibbitt, J. C., Hurst, H. C. and Bhattacharya, S. (2003). Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2. J. Biol. Chem. 278, 16021-16029.
    • (2003) J. Biol. Chem. , vol.278 , pp. 16021-16029
    • Braganca, J.1    Eloranta, J.J.2    Bamforth, S.D.3    Ibbitt, J.C.4    Hurst, H.C.5    Bhattacharya, S.6
  • 8
    • 1842581909 scopus 로고    scopus 로고
    • Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network
    • Brajenovic, M., Joberty, G., Kuster, B., Bouwmeester, T. and Drewes, G. (2004). Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. J. Biol. Chem. 279, 12804-12811.
    • (2004) J. Biol. Chem. , vol.279 , pp. 12804-12811
    • Brajenovic, M.1    Joberty, G.2    Kuster, B.3    Bouwmeester, T.4    Drewes, G.5
  • 9
    • 54549091120 scopus 로고    scopus 로고
    • From cells to organs: building polarized tissue
    • Bryant, D. M. and Mostov, K. E. (2008). From cells to organs: building polarized tissue. Nat. Rev. Mol. Cell Biol. 9, 887-901.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 887-901
    • Bryant, D.M.1    Mostov, K.E.2
  • 11
    • 16844362974 scopus 로고    scopus 로고
    • aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development
    • Chalmers, A. D., Pambos, M., Mason, J., Lang, S., Wylie, C. and Papalopulu, N. (2005). aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development. Development 132, 977-986.
    • (2005) Development , vol.132 , pp. 977-986
    • Chalmers, A.D.1    Pambos, M.2    Mason, J.3    Lang, S.4    Wylie, C.5    Papalopulu, N.6
  • 12
    • 14744289370 scopus 로고    scopus 로고
    • Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
    • Chen, X. and Macara, I. G. (2005). Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nat. Cell Biol. 7, 262-269.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 262-269
    • Chen, X.1    Macara, I.G.2
  • 13
    • 33644530393 scopus 로고    scopus 로고
    • Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
    • Chen, X. and Macara, I. G. (2006). Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly. J. Cell Biol. 172, 671-678.
    • (2006) J. Cell Biol. , vol.172 , pp. 671-678
    • Chen, X.1    Macara, I.G.2
  • 14
    • 85017318518 scopus 로고    scopus 로고
    • Transcription factor AP-2gamma is a core regulator of tight junction biogenesis and cavity formation during mouse early embryogenesis
    • Choi, I., Carey, T. S., Wilson, C. A. and Knott, J. G. (2012). Transcription factor AP-2gamma is a core regulator of tight junction biogenesis and cavity formation during mouse early embryogenesis. Development 139, 4623-4632.
    • (2012) Development , vol.139 , pp. 4623-4632
    • Choi, I.1    Carey, T.S.2    Wilson, C.A.3    Knott, J.G.4
  • 15
    • 0038046388 scopus 로고    scopus 로고
    • Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos
    • Colombo, K., Grill, S. W., Kimple, R. J., Willard, F. S., Siderovski, D. P. and Gönczy, P. (2003). Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science 300, 1957-1961.
    • (2003) Science , vol.300 , pp. 1957-1961
    • Colombo, K.1    Grill, S.W.2    Kimple, R.J.3    Willard, F.S.4    Siderovski, D.P.5    Gönczy, P.6
  • 16
    • 0029862538 scopus 로고    scopus 로고
    • Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis
    • Denker, B. M., Saha, C., Khawaja, S. and Nigam, S. K. (1996). Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis. J. Biol. Chem. 271, 25750-25753.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25750-25753
    • Denker, B.M.1    Saha, C.2    Khawaja, S.3    Nigam, S.K.4
  • 17
    • 84871275879 scopus 로고    scopus 로고
    • STAT3 protein up-regulates Galpha-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis
    • Dunkel, Y., Ong, A., Notani, D., Mittal, Y., Lam, M., Mi, X. and Ghosh, P. (2012). STAT3 protein up-regulates Galpha-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis. J. Biol. Chem. 287, 41667-41683.
    • (2012) J. Biol. Chem. , vol.287 , pp. 41667-41683
    • Dunkel, Y.1    Ong, A.2    Notani, D.3    Mittal, Y.4    Lam, M.5    Mi, X.6    Ghosh, P.7
  • 18
    • 52049125202 scopus 로고    scopus 로고
    • Regulation of epithelial and endothelial junctions by PAR proteins
    • Ebnet, K., Iden, S., Gerke, V. and Suzuki, A. (2008). Regulation of epithelial and endothelial junctions by PAR proteins. Front. Biosci. 13, 6520-6536.
    • (2008) Front. Biosci. , vol.13 , pp. 6520-6536
    • Ebnet, K.1    Iden, S.2    Gerke, V.3    Suzuki, A.4
  • 21
    • 33847154529 scopus 로고    scopus 로고
    • Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
    • Fang, L.,Wang, Y., Du, D., Yang, G., Tak Kwok, T., Kai Kong, S., Chen, B., Chen, D. J. and Chen, Z. (2007). Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair. Cell Res. 17, 100-116.
    • (2007) Cell Res. , vol.17 , pp. 100-116
    • Fang, L.1    Wang, Y.2    Du, D.3    Yang, G.4    Tak Kwok, T.5    Kai Kong, S.6    Chen, B.7    Chen, D.J.8    Chen, Z.9
  • 22
    • 0000752197 scopus 로고
    • Junctional complexes in various epithelia
    • Farquhar, M. G. and Palade, G. E. (1963). Junctional complexes in various epithelia. J. Cell Biol. 17, 375-412.
    • (1963) J. Cell Biol. , vol.17 , pp. 375-412
    • Farquhar, M.G.1    Palade, G.E.2
  • 23
    • 70349306550 scopus 로고    scopus 로고
    • Polarity proteins regulatemammalian cell-cell junctions and cancer pathogenesis
    • Feigin, M. E. and Muthuswamy, S. K. (2009). Polarity proteins regulatemammalian cell-cell junctions and cancer pathogenesis. Curr. Opin. Cell Biol. 21, 694-700.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 694-700
    • Feigin, M.E.1    Muthuswamy, S.K.2
  • 24
    • 0034714094 scopus 로고    scopus 로고
    • Identification of amino acid residues of transcription factor AP-2 involved in DNA binding
    • García, M. A., Campillos, M., Ogueta, S., Valdivieso, F. and Vázquez, J. (2000). Identification of amino acid residues of transcription factor AP-2 involved in DNA binding. J. Mol. Biol. 301, 807-816.
    • (2000) J. Mol. Biol. , vol.301 , pp. 807-816
    • García, M.A.1    Campillos, M.2    Ogueta, S.3    Valdivieso, F.4    Vázquez, J.5
  • 25
    • 62549124627 scopus 로고    scopus 로고
    • GIV is a nonreceptor GEF forG alpha i with a unique motif that regulates Akt signaling
    • Garcia-Marcos, M., Ghosh, P. and Farquhar, M. G. (2009). GIV is a nonreceptor GEF forG alpha i with a unique motif that regulates Akt signaling. Proc. Natl. Acad. Sci. USA 106, 3178-3183.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3178-3183
    • Garcia-Marcos, M.1    Ghosh, P.2    Farquhar, M.G.3
  • 26
    • 77951248135 scopus 로고    scopus 로고
    • A structural determinant that renders G alpha(i) sensitive to activation by GIV/Girdin is required to promote cell migration
    • Garcia-Marcos, M., Ghosh, P., Ear, J. and Farquhar, M. G. (2010). A structural determinant that renders G alpha(i) sensitive to activation by GIV/Girdin is required to promote cell migration. J. Biol. Chem. 285, 12765-12777.
    • (2010) J. Biol. Chem. , vol.285 , pp. 12765-12777
    • Garcia-Marcos, M.1    Ghosh, P.2    Ear, J.3    Farquhar, M.G.4
  • 27
    • 79551648550 scopus 로고    scopus 로고
    • Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer
    • Garcia-Marcos, M., Jung, B. H., Ear, J., Cabrera, B., Carethers, J. M. and Ghosh, P. (2011). Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer. FASEB J. 25, 590-599.
    • (2011) FASEB J. , vol.25 , pp. 590-599
    • Garcia-Marcos, M.1    Jung, B.H.2    Ear, J.3    Cabrera, B.4    Carethers, J.M.5    Ghosh, P.6
  • 28
    • 48249106623 scopus 로고    scopus 로고
    • Activation of Galphai3 triggers cell migration via regulation of GIV
    • Ghosh, P., Garcia-Marcos, M., Bornheimer, S. J. and Farquhar, M. G. (2008). Activation of Galphai3 triggers cell migration via regulation of GIV. J. Cell Biol. 182, 381-393.
    • (2008) J. Cell Biol. , vol.182 , pp. 381-393
    • Ghosh, P.1    Garcia-Marcos, M.2    Bornheimer, S.J.3    Farquhar, M.G.4
  • 29
    • 35549001736 scopus 로고    scopus 로고
    • The PAR proteins: fundamental players in animal cell polarization
    • Goldstein, B. and Macara, I. G. (2007). The PAR proteins: fundamental players in animal cell polarization. Dev. Cell 13, 609-622.
    • (2007) Dev. Cell , vol.13 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 31
    • 0034745355 scopus 로고    scopus 로고
    • Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos
    • Gotta, M. and Ahringer, J. (2001). Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos. Nat. Cell Biol. 3, 297-300.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 297-300
    • Gotta, M.1    Ahringer, J.2
  • 32
    • 0037665297 scopus 로고    scopus 로고
    • Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo
    • Gotta, M., Dong, Y., Peterson, Y. K., Lanier, S. M. and Ahringer, J. (2003). Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo. Curr. Biol. 13, 1029-1037.
    • (2003) Curr. Biol. , vol.13 , pp. 1029-1037
    • Gotta, M.1    Dong, Y.2    Peterson, Y.K.3    Lanier, S.M.4    Ahringer, J.5
  • 33
    • 0020623250 scopus 로고
    • Participation of plasma membrane proteins in the formation of tight junction by cultured epithelial cells
    • Griepp, E. B., Dolan,W. J., Robbins, E. S. and Sabatini, D. D. (1983). Participation of plasma membrane proteins in the formation of tight junction by cultured epithelial cells. J. Cell Biol. 96, 693-702.
    • (1983) J. Cell Biol. , vol.96 , pp. 693-702
    • Griepp, E.B.1    Dolan, W.J.2    Robbins, E.S.3    Sabatini, D.D.4
  • 34
    • 33646127606 scopus 로고    scopus 로고
    • PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains
    • Hirose, T., Karasawa, M., Sugitani, Y., Fujisawa, M., Akimoto, K., Ohno, S. and Noda, T. (2006). PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. Development 133, 1389-1398.
    • (2006) Development , vol.133 , pp. 1389-1398
    • Hirose, T.1    Karasawa, M.2    Sugitani, Y.3    Fujisawa, M.4    Akimoto, K.5    Ohno, S.6    Noda, T.7
  • 36
    • 67449114979 scopus 로고    scopus 로고
    • Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells
    • Horikoshi, Y., Suzuki, A., Yamanaka, T., Sasaki, K., Mizuno, K., Sawada, H., Yonemura, S. and Ohno, S. (2009). Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. J. Cell Sci. 122, 1595-1606.
    • (2009) J. Cell Sci. , vol.122 , pp. 1595-1606
    • Horikoshi, Y.1    Suzuki, A.2    Yamanaka, T.3    Sasaki, K.4    Mizuno, K.5    Sawada, H.6    Yonemura, S.7    Ohno, S.8
  • 37
    • 0344663968 scopus 로고    scopus 로고
    • Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia
    • Hurd, T. W., Fan, S., Liu, C.-J., Kweon, H. K., Hakansson, K. and Margolis, B. (2003). Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia. Curr. Biol. 13, 2082-2090.
    • (2003) Curr. Biol. , vol.13 , pp. 2082-2090
    • Hurd, T.W.1    Fan, S.2    Liu, C.-J.3    Kweon, H.K.4    Hakansson, K.5    Margolis, B.6
  • 38
    • 2942626082 scopus 로고    scopus 로고
    • Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis
    • Hutterer, A., Betschinger, J., Petronczki, M. and Knoblich, J. A. (2004). Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Dev. Cell 6, 845-854.
    • (2004) Dev. Cell , vol.6 , pp. 845-854
    • Hutterer, A.1    Betschinger, J.2    Petronczki, M.3    Knoblich, J.A.4
  • 39
    • 33744520896 scopus 로고    scopus 로고
    • Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex
    • Imai, F., Hirai, S.-i., Akimoto, K., Koyama, H., Miyata, T., Ogawa, M., Noguchi, S., Sasaoka, T., Noda, T. and Ohno, S. (2006). Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development 133, 1735-1744.
    • (2006) Development , vol.133 , pp. 1735-1744
    • Imai, F.1    Hirai, S.-i.2    Akimoto, K.3    Koyama, H.4    Miyata, T.5    Ogawa, M.6    Noguchi, S.7    Sasaoka, T.8    Noda, T.9    Ohno, S.10
  • 40
    • 59649104201 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of vascular lumen formation
    • Iruela-Arispe, M. L. and Davis, G. E. (2009). Cellular and molecular mechanisms of vascular lumen formation. Dev. Cell 16, 222-231.
    • (2009) Dev. Cell , vol.16 , pp. 222-231
    • Iruela-Arispe, M.L.1    Davis, G.E.2
  • 42
    • 0032487494 scopus 로고    scopus 로고
    • An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
    • Izumi, Y., Hirose, T., Tamai,Y.,Hirai, S.-i., Nagashima, Y., Fujimoto, T., Tabuse, Y., Kemphues, K. J. and Ohno, S. (1998). An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J. Cell Biol. 143, 95-106.
    • (1998) J. Cell Biol. , vol.143 , pp. 95-106
    • Izumi, Y.1    Hirose, T.2    Tamai, Y.3    Hirai, S.-i.4    Nagashima, Y.5    Fujimoto, T.6    Tabuse, Y.7    Kemphues, K.J.8    Ohno, S.9
  • 44
    • 0034253536 scopus 로고    scopus 로고
    • The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
    • Joberty, G., Petersen, C., Gao, L. and Macara, I. G. (2000). The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat. Cell Biol. 2, 531-539.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 531-539
    • Joberty, G.1    Petersen, C.2    Gao, L.3    Macara, I.G.4
  • 46
    • 78649439321 scopus 로고    scopus 로고
    • Asymmetric cell division: recent developments and their implications for tumour biology
    • Knoblich, J. A. (2010). Asymmetric cell division: recent developments and their implications for tumour biology. Nat. Rev. Mol. Cell Biol. 11, 849-860.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 849-860
    • Knoblich, J.A.1
  • 47
    • 38749151658 scopus 로고    scopus 로고
    • Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling
    • Koh, W., Mahan, R. D. and Davis, G. E. (2008). Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling. J. Cell Sci. 121, 989-1001.
    • (2008) J. Cell Sci. , vol.121 , pp. 989-1001
    • Koh, W.1    Mahan, R.D.2    Davis, G.E.3
  • 48
    • 70349857695 scopus 로고    scopus 로고
    • Par-3 partitioning defective 3 homolog (C. elegans) and androgen-induced prostate proliferative shutoff associated protein genes are mutationally inactivated in prostate cancer cells
    • Kunnev, D., Ivanov, I. and Ionov, Y. (2009). Par-3 partitioning defective 3 homolog (C. elegans) and androgen-induced prostate proliferative shutoff associated protein genes are mutationally inactivated in prostate cancer cells. BMC Cancer 9, 318.
    • (2009) BMC Cancer , vol.9 , pp. 318
    • Kunnev, D.1    Ivanov, I.2    Ionov, Y.3
  • 49
    • 20444472383 scopus 로고    scopus 로고
    • Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles
    • Le-Niculescu, H., Niesman, I., Fischer, T., DeVries, L. and Farquhar, M. G. (2005). Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles. J. Biol. Chem. 280, 22012-22020.
    • (2005) J. Biol. Chem. , vol.280 , pp. 22012-22020
    • Le-Niculescu, H.1    Niesman, I.2    Fischer, T.3    DeVries, L.4    Farquhar, M.G.5
  • 50
    • 0000202186 scopus 로고    scopus 로고
    • A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity
    • Lin, D., Edwards, A. S., Fawcett, J. P., Mbamalu, G., Scott, J. D. and Pawson, T. (2000). A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat. Cell Biol. 2, 540-547.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 540-547
    • Lin, D.1    Edwards, A.S.2    Fawcett, J.P.3    Mbamalu, G.4    Scott, J.D.5    Pawson, T.6
  • 52
    • 0037428084 scopus 로고    scopus 로고
    • Tube morphogenesis: making and shaping biological tubes
    • Lubarsky, B. and Krasnow, M. A. (2003). Tube morphogenesis: making and shaping biological tubes. Cell 112, 19-28.
    • (2003) Cell , vol.112 , pp. 19-28
    • Lubarsky, B.1    Krasnow, M.A.2
  • 53
    • 0022451875 scopus 로고
    • Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity
    • Madara, J. L., Barenberg, D. and Carlson, S. (1986). Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity. J. Cell Biol. 102, 2125-2136.
    • (1986) J. Cell Biol. , vol.102 , pp. 2125-2136
    • Madara, J.L.1    Barenberg, D.2    Carlson, S.3
  • 55
    • 77954592554 scopus 로고    scopus 로고
    • Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines
    • Nolens, G., Pignon, J.-C., Koopmansch, B., Elmoualij, B., Zorzi,W., De Pauw, E. and Winkler, R. (2009). Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines. Breast Cancer Res. 11, R83.
    • (2009) Breast Cancer Res. , vol.11 , pp. R83
    • Nolens, G.1    Pignon, J.-C.2    Koopmansch, B.3    Elmoualij, B.4    Zorzi, W.5    De Pauw, E.6    Winkler, R.7
  • 56
    • 0036636095 scopus 로고    scopus 로고
    • Opinion: Building epithelial architecture: insights from three-dimensional culture models
    • O'Brien, L. E., Zegers, M. M. and Mostov, K. E. (2002). Opinion: Building epithelial architecture: insights from three-dimensional culture models. Nat. Rev. Mol. Cell Biol. 3, 531-537.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 531-537
    • O'Brien, L.E.1    Zegers, M.M.2    Mostov, K.E.3
  • 58
    • 35648951092 scopus 로고    scopus 로고
    • Nerve growth factor induces endothelial cell invasion and cord formation by promoting matrix metalloproteinase-2 expression through the phosphatidylinositol 3-kinase/Akt signaling pathway and AP-2 transcription factor
    • Park, M.-J., Kwak, H.-J., Lee, H.-C., Yoo, D.-H., Park, I.-C., Kim, M.-S., Lee, S.-H., Rhee, C. H. and Hong, S.-I. (2007). Nerve growth factor induces endothelial cell invasion and cord formation by promoting matrix metalloproteinase-2 expression through the phosphatidylinositol 3-kinase/Akt signaling pathway and AP-2 transcription factor. J. Biol. Chem. 282, 30485-30496.
    • (2007) J. Biol. Chem. , vol.282 , pp. 30485-30496
    • Park, M.-J.1    Kwak, H.-J.2    Lee, H.-C.3    Yoo, D.-H.4    Park, I.-C.5    Kim, M.-S.6    Lee, S.-H.7    Rhee, C.H.8    Hong, S.-I.9
  • 60
    • 0035542952 scopus 로고    scopus 로고
    • Activator protein 2alpha transcription factor expression is associated with luminal differentiation and is lost in prostate cancer
    • Ruiz, M., Troncoso, P., Bruns, C. and Bar-Eli, M. (2001). Activator protein 2alpha transcription factor expression is associated with luminal differentiation and is lost in prostate cancer. Clin. Cancer Res. 7, 4086-4095.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 4086-4095
    • Ruiz, M.1    Troncoso, P.2    Bruns, C.3    Bar-Eli, M.4
  • 61
    • 0032555295 scopus 로고    scopus 로고
    • Involvement of Galphai2 in the maintenance and biogenesis of epithelial cell tight junctions
    • Saha, C., Nigam, S. K. and Denker, B. M. (1998). Involvement of Galphai2 in the maintenance and biogenesis of epithelial cell tight junctions. J. Biol. Chem. 273, 21629-21633.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21629-21633
    • Saha, C.1    Nigam, S.K.2    Denker, B.M.3
  • 62
    • 0019133797 scopus 로고
    • Tight junction formation in the establishment of intramembranous particle polarity in aggregating MDCK cells
    • Sang, U. H., Saier, M. H., Jr and Ellisman, M. H. (1980). Tight junction formation in the establishment of intramembranous particle polarity in aggregating MDCK cells. Exp. Cell Res. 128, 223-235.
    • (1980) Exp. Cell Res. , vol.128 , pp. 223-235
    • Sang, U.H.1    Saier Jr, M.H.2    Ellisman, M.H.3
  • 64
    • 25444528729 scopus 로고    scopus 로고
    • The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
    • Siderovski, D. P. and Willard, F. S. (2005). The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits. Int. J. Biol. Sci. 1, 51-66.
    • (2005) Int. J. Biol. Sci. , vol.1 , pp. 51-66
    • Siderovski, D.P.1    Willard, F.S.2
  • 65
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • Simon, M. I., Strathmann, M. P. and Gautam, N. (1991). Diversity of G proteins in signal transduction. Science 252, 802-808.
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 67
    • 0028289263 scopus 로고
    • Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells
    • Stevenson, B. R. and Begg, D. A. (1994). Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J. Cell Sci. 107, 367-375.
    • (1994) J. Cell Sci. , vol.107 , pp. 367-375
    • Stevenson, B.R.1    Begg, D.A.2
  • 68
    • 33645746316 scopus 로고    scopus 로고
    • The PAR-aPKC system: lessons in polarity
    • Suzuki, A. and Ohno, S. (2006). The PAR-aPKC system: lessons in polarity. J. Cell Sci. 119, 979-987.
    • (2006) J. Cell Sci. , vol.119 , pp. 979-987
    • Suzuki, A.1    Ohno, S.2
  • 69
    • 0035911955 scopus 로고    scopus 로고
    • Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures
    • Suzuki, A., Yamanaka, T., Hirose, T., Manabe, N., Mizuno, K., Shimizu, M., Akimoto, K., Izumi, Y., Ohnishi, T. and Ohno, S. (2001). Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J. Cell Biol. 152, 1183-1196.
    • (2001) J. Cell Biol. , vol.152 , pp. 1183-1196
    • Suzuki, A.1    Yamanaka, T.2    Hirose, T.3    Manabe, N.4    Mizuno, K.5    Shimizu, M.6    Akimoto, K.7    Izumi, Y.8    Ohnishi, T.9    Ohno, S.10
  • 71
    • 44449156338 scopus 로고    scopus 로고
    • Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis
    • Torkko, J. M., Manninen, A., Schuck, S. and Simons, K. (2008). Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis. J. Cell Sci. 121, 1193-1203.
    • (2008) J. Cell Sci. , vol.121 , pp. 1193-1203
    • Torkko, J.M.1    Manninen, A.2    Schuck, S.3    Simons, K.4
  • 72
  • 73
    • 0023227132 scopus 로고
    • Modulation of the expression of an apical plasma membrane protein of Madin-Darby canine kidney epithelial cells: cell-cell interactions control the appearance of a novel intracellular storage compartment
    • Vega-Salas, D. E., Salas, P. J. and Rodriguez-Boulan, E. (1987). Modulation of the expression of an apical plasma membrane protein of Madin-Darby canine kidney epithelial cells: cell-cell interactions control the appearance of a novel intracellular storage compartment. J. Cell Biol. 104, 1249-1259.
    • (1987) J. Cell Biol. , vol.104 , pp. 1249-1259
    • Vega-Salas, D.E.1    Salas, P.J.2    Rodriguez-Boulan, E.3
  • 74
    • 0024110256 scopus 로고
    • Exocytosis of vacuolar apical compartment (VAC): a cell-cell contact controlled mechanism for the establishment of the apical plasma membrane domain in epithelial cells
    • Vega-Salas, D. E., Salas, P. J. and Rodriguez-Boulan, E. (1988). Exocytosis of vacuolar apical compartment (VAC): a cell-cell contact controlled mechanism for the establishment of the apical plasma membrane domain in epithelial cells. J. Cell Biol. 107, 1717-1728.
    • (1988) J. Cell Biol. , vol.107 , pp. 1717-1728
    • Vega-Salas, D.E.1    Salas, P.J.2    Rodriguez-Boulan, E.3
  • 75
    • 0033518223 scopus 로고    scopus 로고
    • Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts
    • Wodarz, A., Ramrath, A., Kuchinke, U. and Knust, E. (1999). Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts. Nature 402, 544-547.
    • (1999) Nature , vol.402 , pp. 544-547
    • Wodarz, A.1    Ramrath, A.2    Kuchinke, U.3    Knust, E.4
  • 76
    • 0034683578 scopus 로고    scopus 로고
    • Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts
    • Wodarz, A., Ramrath, A., Grimm, A. and Knust, E. (2000). Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts. J. Cell Biol. 150, 1361-1374.
    • (2000) J. Cell Biol. , vol.150 , pp. 1361-1374
    • Wodarz, A.1    Ramrath, A.2    Grimm, A.3    Knust, E.4
  • 77
    • 14044255938 scopus 로고    scopus 로고
    • Involvement of the annexin II-S100A10 complex in the formation of E-cadherin-based adherens junctions in Madin-Darby canine kidney cells
    • Yamada, A., Irie, K., Hirota, T., Ooshio, T., Fukuhara, A. and Takai, Y. (2005). Involvement of the annexin II-S100A10 complex in the formation of E-cadherin-based adherens junctions in Madin-Darby canine kidney cells. J. Biol. Chem. 280, 6016-6027.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6016-6027
    • Yamada, A.1    Irie, K.2    Hirota, T.3    Ooshio, T.4    Fukuhara, A.5    Takai, Y.6
  • 79
    • 33745217610 scopus 로고    scopus 로고
    • Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity
    • Yamanaka, T., Horikoshi, Y., Izumi, N., Suzuki, A., Mizuno, K. and Ohno, S. (2006). Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity. J. Cell Sci. 119, 2107-2118.
    • (2006) J. Cell Sci. , vol.119 , pp. 2107-2118
    • Yamanaka, T.1    Horikoshi, Y.2    Izumi, N.3    Suzuki, A.4    Mizuno, K.5    Ohno, S.6
  • 81
    • 0032956497 scopus 로고    scopus 로고
    • New perspectives on mechanisms involved in generating epithelial cell polarity
    • Yeaman, C., Grindstaff, K. K. and Nelson, W. J. (1999). New perspectives on mechanisms involved in generating epithelial cell polarity. Physiol. Rev. 79, 73-98.
    • (1999) Physiol. Rev. , vol.79 , pp. 73-98
    • Yeaman, C.1    Grindstaff, K.K.2    Nelson, W.J.3
  • 83
    • 66249115336 scopus 로고    scopus 로고
    • The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro
    • Zuo, X., Guo, W. and Lipschutz, J. H. (2009). The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro. Mol. Biol. Cell 20, 2522-2529.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 2522-2529
    • Zuo, X.1    Guo, W.2    Lipschutz, J.H.3


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