Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming

Oncogene

Volumn 35, Issue 12, 2016, Pages 1585-1595

  Srinivasan, S ^a   Guha, M ^a   Dong, D W ^a   Whelan, K A ^b   Ruthel, G ^a   Uchikado, Y ^c   Natsugoe, S ^c   Nakagawa, H ^b   Avadhani, N G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYTOCHROME C OXIDASE; MATRIX METALLOPROTEINASE 16; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ESOPHAGUS TUMOR; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GLYCOLYSIS; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; METABOLIC PARAMETERS; METABOLIC REPROGRAMMING; MITOCHONDRIAL DNA DEPLETION; MORPHOGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; GENETICS; METABOLISM; MOUSE; OXIDATIVE STRESS;

ANIMALS; CELL LINE; ELECTRON TRANSPORT COMPLEX IV; GENE SILENCING; MICE; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84935482101     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.227     Document Type: Article

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