In silico prediction and experimental confirmation of HA residues conferring enhanced human receptor specificity of H5N1 influenza A viruses

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Schmier, Sonja ^a,f   Mostafa, Ahmed ^b,c   Haarmann, Thomas ^a,g   Bannert, Norbert ^d   Ziebuhr, John ^b   Veljkovic, Veljko ^e   Dietrich, Ursula ^a   Pleschka, Stephan ^b  

^a INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c NATIONAL RESEARCH CENTRE   (Egypt)

^d ROBERT KOCH INSTITUTE   (Germany)

^e UNIVERSITY OF BELGRADE   (Serbia)

^f B Braun Melsungen AG   (Germany)

^g AB Enzymes GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; INFLUENZA VIRUS HEMAGGLUTININ; VIRUS RECEPTOR;

ANIMAL; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; COMPUTER SIMULATION; GENE EXPRESSION; GENE VECTOR; GENETICS; HUMAN; INFLUENZA A VIRUS (H5N1); METABOLISM; MOLECULAR MODEL; MUTATION; PHENOTYPE; PROTEIN CONFORMATION; RETROVIRIDAE; VIRUS ATTACHMENT; VIRUS REPLICATION;

AMINO ACIDS; ANIMALS; CELL LINE; COMPUTER SIMULATION; GENE EXPRESSION; GENETIC VECTORS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTATION; PHENOTYPE; PROTEIN CONFORMATION; RECEPTORS, VIRUS; RETROVIRIDAE; VIRUS ATTACHMENT; VIRUS REPLICATION;

EID: 84935012627     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep11434     Document Type: Article

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