Application of the EIIP/ISM bioinformatics concept in development of new drugs

Current Medicinal Chemistry

Volumn 14, Issue 4, 2007, Pages 441-453

  Veljkovic, V ^a   Veljkovic, N ^a   Este J A ^b   Huther A ^c   Dietrich, U ^c  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^c INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

Author keywords

Drug development; EIIP ISM concept; HIV 1 entry inhibitors; Virtual screening

Indexed keywords

4 (2 AMINOETHYL)PIPERIDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT; APLAVIROC; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; E 913; E 916; E 917; INTEGRASE INHIBITOR; MARAVIROC; N [4 [[[6,7 DIHYDRO 2 (4 METHYLPHENYL) 5H BENZOCYCLOHEPTEN 8 YL]CARBONYL]AMINO]BENZYL] N,N DIMETHYL 2H TETRAHYDROPYRAN 4 AMINIUM CHLORIDE; NEW DRUG; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; TAK 5H; UK 107543; UK 179645; UK 370907; UK 372673; UK 374503; UK 374692; UK 378995; UK 382055; UK 395859; UK 396794; UK 408030; UK 418526; UK 427857 41; UNCLASSIFIED DRUG; UNINDEXED DRUG; VICRIVIROC;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIVIRAL ACTIVITY; BIOINFORMATICS; CLINICAL TRIAL; COST BENEFIT ANALYSIS; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IC 50; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; REVIEW; VIRUS ISOLATION;

ANTI-HIV AGENTS; COMPUTATIONAL BIOLOGY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HUMANS; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33847215785     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986707779941014     Document Type: Review

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