PTEN/Akt-p27kip1 Signaling Promote the BM-MSCs Senescence and Apoptosis in SLE Patients

Journal of Cellular Biochemistry

Volumn 116, Issue 8, 2015, Pages 1583-1594

  Tan, Wei ^a,b   Gu, Zhifeng ^a   Shen, Biyu ^a   Jiang, Jinxia ^a   Meng, Yan ^a   Da, Zhanyun ^a   Liu, Hong ^c   Tao, Tao ^c   Cheng, Chun ^c  

^a NANTONG UNIVERSITY   (China)

^b Medical College of Southeast University   (China)

^c NANTONG MEDICAL COLLEGE   (China)

Author keywords

APOPTOSIS; BONE MARROW MESENCHYMAL STEM CELLS; IMMUNOREGULATION; P27kip1; PTEN AKT SIGNALING; SENESCENCE; SYSTEMIC LUPUS ERYTHEMATOSUS

Indexed keywords

BETA GALACTOSIDASE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; LIPOCORTIN 5; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN 27 KINASE INHIBITION PROTEIN 1; PROTEIN KINASE B; PROTEIN P27; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CDKN1B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PTEN PROTEIN, HUMAN;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CD4+ T LYMPHOCYTE; CELL COUNT; CELL CYCLE ARREST; CELL GROWTH; CELL ISOLATION; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CLINICAL ARTICLE; COCULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ACTIVITY; DOWN REGULATION; ENZYME ASSAY; FEMALE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOREGULATION; MTT ASSAY; PRIMARY CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; SIGNAL TRANSDUCTION; SLEDAI; SYSTEMIC LUPUS ERYTHEMATOSUS; TH17 CELL; TUNEL ASSAY; UPREGULATION; WESTERN BLOTTING; YOUNG ADULT; CELL AGING; CELL CULTURE; GENE EXPRESSION REGULATION; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY;

MUS;

ADOLESCENT; ADULT; APOPTOSIS; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; GENE EXPRESSION REGULATION; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MESENCHYMAL STROMAL CELLS; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84935008178     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.25112     Document Type: Article

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