Exquisitely Specific Bisubstrate Inhibitors of c-Src Kinase

ACS Chemical Biology

Volumn 10, Issue 6, 2015, Pages 1387-1391

  Brandvold, Kristoffer R ^a   Santos, Shana M ^a   Breen, Meghan E ^a   Lachacz, Eric J ^a   Steffey, Michael E ^a   Soellner, Matthew B ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C SRC KINASE INHIBITOR; PHOSPHOTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; CSK TYROSINE-PROTEIN KINASE; PEPTIDE; PROTEIN BINDING; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE;

ARTICLE; CELL PERMEABILIZATION; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG TARGETING; METHODOLOGY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; BINDING COMPETITION; CELL MEMBRANE PERMEABILITY; CHEMISTRY; ENZYME SPECIFICITY; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; IC50; METABOLISM; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; BINDING, COMPETITIVE; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; GENE EXPRESSION; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84934991976     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb501048b     Document Type: Article

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