Tramadol and tramadol+caffeine synergism in the rat formalin test are mediated by central opioid and serotonergic mechanisms

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Carrillo Munguía, Norma ^a   González Trujano, Ma Eva ^b   Huerta, Miguel ^a   Trujillo, Xochitl ^a   Díaz Reval, M Irene ^a  

^a UNIVERSIDAD DE COLIMA   (Mexico)

^b INSTITUTO NACIONAL DE PSIQUIATRÍA RAMÓN DE LA FUENTE MUÑIZ   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; KETANSERIN; NALOXONE; ONDANSETRON; OPIATE RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN 3 RECEPTOR; TRAMADOL; NARCOTIC ANALGESIC AGENT;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENTIATION; FORMALIN TEST; MALE; NONHUMAN; RAT; SEROTONINERGIC SYSTEM; SPINAL CORD; ANIMAL; DRUG EFFECTS; METABOLISM; PAIN; PAIN MEASUREMENT; PATHOPHYSIOLOGY;

RATTUS;

ANALGESICS, OPIOID; ANIMALS; CAFFEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; KETANSERIN; NALOXONE; ONDANSETRON; PAIN; PAIN MEASUREMENT; RATS; TRAMADOL;

EID: 84934986356     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/686424     Document Type: Article

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