Input-Specific Modulation of Neurotransmitter Release in the Lateral Horn of the Spinal Cord via Adenosine Receptors

Journal of Neuroscience

Volumn 24, Issue 1, 2004, Pages 127-137

  Brooke, Ruth E ^a   Deuchars, Jim ^a   Deuchars, Susan A ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Adenosine; Autonomic; Immunoreactivity; Patch clamp; Spinal; Sympathetic

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE RECEPTOR; NEUROTRANSMITTER;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; ELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; FEMALE; GRAY MATTER; IMMUNOREACTIVITY; INHIBITORY POSTSYNAPTIC POTENTIAL; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP; POSTSYNAPTIC MEMBRANE; PREGANGLIONIC NERVE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE; SYNAPTIC TRANSMISSION; THORACIC SPINAL CORD;

ADENOSINE; ANIMALS; CELLS, CULTURED; EXCITATORY POSTSYNAPTIC POTENTIALS; IMMUNOHISTOCHEMISTRY; INTERNEURONS; MALE; NEURAL INHIBITION; NEURONS; NEUROTRANSMITTER AGENTS; PATCH-CLAMP TECHNIQUES; PHENETHYLAMINES; PRESYNAPTIC TERMINALS; RATS; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; SPINAL CORD; TRIAZINES; TRIAZOLES;

EID: 0842344417     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4591-03.2004     Document Type: Article

References (59)

1. Aden U, Halldner L, Lagercrantz H, Dalmau I, Ledent C, Fredholm BB (2003) Aggravated brain damage after hypoxic ischemia in immature adenosine A2A knockout mice. Stroke 34:739-744.
2. Ambalavanar R, Morris R (1989) Fluoro-gold injected either subcutaneously or intravascularly results in extensive retrograde labelling of CNS neurones having axons terminating outside the blood-brain barrier. Brain Res 505:171-175.
3. Anderson CR, Edwards SL (1994) Intraperitoneal injections of fluorogold reliably labels all sympathetic preganglionic neurons in the rat. J Neurosci Methods 53:137-141.
4. Barraco RA, Martens KA, Parizon M, Normile HJ (1993) Adenosine A2a receptors in the nucleus accumbens mediate locomotor depression. Brain Res Bull 31:397-404.
5. Blum D, Hourez R, Galas MC, Popoli P, Schiffmann SN (2003) Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics. Lancet Neurol 2:366-374.
6. Brooke RE, Pyner S, McLeish P, Buchan S, Deuchars J, Deuchars SA (2002) Spinal cord interneurones labelled transneuronally from the adrenal gland by a GFP-herpes virus construct contain the potassium channel subunit Kv3.1b. Auton Neurosci 98:45-50.
7. Chau D, Johns DG, Schramm LP (2000) Ongoing and stimulus-evoked activity of sympathetically correlated neurons in the intermediate zone and dorsal horn of acutely spinalized rats. J Neurophysiol 83:2699-2707.
8. Choca JI, Proudfit HK, Green RD (1987) Identification of A1 and A2 adenosine receptors in the rat spinal cord. J Pharmacol Exp Ther 242:905-910.
9. Choca JI, Green RD, Proudfit HK (1988) Adenosine A1 and A2 receptors of the substantia gelatinosa are located predominantly on intrinsic neurons: an autoradiography study. J Pharmacol Exp Ther 247:757-764.
10. Correia-de-Sa P, Ribeiro JA (1994a) Potentiation by tonic A2a-adenosine receptor activation of CGRP-facilitated [3H]-ACh release from rat motor nerve endings. Br J Pharmacol 111:582-588.
11. Correia-de-Sa P, Ribeiro JA (1994b) Tonic adenosine A2A receptor activation modulates nicotinic autoreceptor function at the rat neuromuscular junction. Eur J Pharmacol 271:349-355.
12. Correia-de-Sa P, Timoteo MA, Ribeiro JA (1996) Presynaptic A1 inhibitory/A2A facilitatory adenosine receptor activation balance depends on motor nerve stimulation paradigm at the rat hemidiaphragm. J Neurophysiol 76:3910-3919.
13. Cunha RA, Ribeiro JA (2000) Purinergic modulation of [(3)H]GABA release from rat hippocampal nerve terminals. Neuropharmacology 39:1156-1167.
14. Cunha RA, Milusheva E, Vizi ES, Ribeiro JA, Sebastiao AM (1994) Excitatory and inhibitory effects of A1 and A2A adenosine receptor activation on the electrically evoked [3H] acetylcholine release from different areas of the rat hippocampus. J Neurochem 63:207-214.
15. Cunha RA, Correia-de-Sa P, Sebastiao AM, Ribeiro JA (1996) Preferential activation of excitatory adenosine receptors at rat hippocampal and neuromuscular synapses by adenosine formed from released adenine nucleotides. Br J Pharmacol 119:253-260.
16. Daly JW, Butts-Lamb P, Padgett W (1983) Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines. Cell Mol Neurobiol 3:69-80.
17. Dembowsky K, Czachurski J, Seller H (1985) An intracellular study of the synaptic input to sympathetic preganglionic neurones of the third thoracic segment of the cat. J Auton Nerv Syst 13:201-244.
18. Deuchars SA, Morrison SF, Gilbey MP (1995) Medullary-evoked EPSPs in neonatal rat sympathetic preganglionic neurones in vitro. J Physiol (Lond) 487:453-463.
19. Deuchars SA, Spyer KM, Gilbey MP (1997) Stimulation within the rostral ventrolateral medulla can evoke monosynaptic GABAergic IPSPs in sympathetic preganglionic neurons in vitro. J Neurophysiol 77:229-235.
20. Deuchars SA, Brooke RE, Frater B, Deuchars J (2001a) Properties of interneurones in the intermediolateral cell column of the rat spinal cord: role of the potassium channel subunit Kv3.1. Neuroscience 106:433-446.
21. Deuchars SA, Brooke RE, Deuchars J (2001b) Adenosine A1 receptors reduce release from excitatory but not inhibitory synaptic inputs onto lateral horn neurons. J Neurosci 21:6308-6320.
22. Deuchars SA, Atkinson L, Brooke RE, Musa H, Milligan CJ, Batten TF, Buckley NJ, Parson SH, Deuchars J (2001c) Neuronal P2X7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems. J Neurosci 21:7143-7152.
23. Ferre S, Fredholm BB, Morelli M, Popoli P, Fuxe K (1997) Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci 20:482-487.
24. Fowler JC (1989) Adenosine antagonists delay hypoxia-induced depression of neuronal activity in hippocampal brain slice. Brain Res 490:378-384.
25. Hara H, Sukamoto T, Kogure K (1993) Mechanism and pathogenesis of ischemia-induced neuronal damage. Prog Neurobiol 40:645-670.
26. Jarvis MF, Williams M (1989) Direct auto radiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist, [3H] CGS 21680. Eur J Pharmacol 168:243-246.
27. Jones PA, Smith RA, Stone TW (1998) Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists. Neuroscience 85:229-237.
28. Joshi S, Levatte MA, Dekaban GA, Weaver LC (1995) Identification of spinal interneurons antecedent to adrenal sympathetic preganglionic neurons using trans-synaptic transport of herpes simplex virus type 1. Neuroscience 65:893-903.
29. Kaelin-Lang A, Lauterburg T, Burgunder JM (1999) Expression of adenosine A2a receptors gene in the olfactory bulb and spinal cord of rat and mouse. Neurosci Lett 261:189-191.
30. Katchman AN, Hershkowitz N (1993) Adenosine antagonists prevent hypoxia-induced depression of excitatory but not inhibitory synaptic currents. Neurosci Lett 159:123-126.
31. Kirk IP, Richardson PJ (1995) Inhibition of striatal GABA release by the adenosine A2a receptor is not mediated by increases in cyclic AMP. J Neurochem 64:2801-2809.
32. Koh HC, Shin IC, Hwang SJ, Paik DJ (1996) Modification of cardiovascular response of adenosine A1 receptor agonist by cyclic AMP in the spinal cord of the rats. Neurosci Lett 219:195-198.
33. Koh HC, Lee TK, Kang JS, Lee CH, Lee H, Paik DJ, Shin IC (2000) Modification of cardiovascular response of adenosine A2 receptor agonist by adenylate cyclase in the spinal cord of rats. Neurosci Lett 293:45-48.
34. Kurokawa M, Kirk IP, Kirkpatrick KA, Kase H, Richardson PJ (1994) Inhibition by KF17837 of adenosine A2A receptor-mediated modulation of striatal GABA and ACh release. Br J Pharmacol 113:43-48.
35. Li H, Henry JL (1998) Adenosine A2 receptor mediation of pre- and postsynaptic excitatory effects of adenosine in rat hippocampus in vitro. Eur J Pharmacol 347:173-182.
36. Lopes LV, Cunha RA, Ribeiro JA (1999a) ZM 241385, an adenosine A(2A) receptor antagonist, inhibits hippocampal A(1) receptor responses. Eur J Pharmacol 383:395-398.
37. Lopes LV, Cunha RA, Ribeiro JA (1999b) Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats. J Neurophysiol 82:3196-3203.
38. Lynge J, Hellsten Y (2000) Distribution of adenosine A1, A2A and A2B receptors in human skeletal muscle. Acta Physiol Scand 169:283-290.
39. Mayfield RD, Suzuki F, Zahniser NR (1993) Adenosine A2a receptor modulation of electrically evoked endogenous GABA release from slices of rat globus pallidus. J Neurochem 60:2334-2337.
40. Mori A, Shindou T, Ichimura M, Nonaka H, Kase H (1996) The role of adenosine A2a receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons. J Neurosci 16:605-611.
41. Ongini E, Adami M, Ferri C, Bertorelli R (1997) Adenosine A2A receptors and neuroprotection. Ann NY Acad Sci 825:30-48.
42. Parkinson FE, Fredholm BB (1990) Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand. Naunyn Schmiedebergs Arch Pharmacol 342:85-89.
43. Patel MK, Pinnock RD, Lee K (2001) Adenosine exerts multiple effects in dorsal horn neurones of the adult rat spinal cord. Brain Res 920:19-26.
44. Pedata F, Corsi C, Melani A, Bordoni F, Latini S (2001) Adenosine extracellular brain concentrations and role of A2A receptors in ischemia. Ann NY Acad Sci 939:74-84.
45. Poucher SM, Keddie JR, Singh P, Stoggall SM, Caulkett PW, Jones G, Coll MG (1995) The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2a selective adenosine receptor antagonist. Br J Pharmacol 115:1096-1102.
46. Rebola N, Oliveira CR, Cunha RA (2002) Transducing system operated by adenosine A(2A) receptors to facilitate acetylcholine release in the rat hippocampus. Eur J Pharmacol 454:31-38.
47. Rosin DL, Robeva A, Woodard RL, Guyenet PG, Linden J (1998) Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system. J Comp Neurol 401:163-186.
48. Schramm LP, Livingstone RH (1987) Inhibition of renal nerve sympathetic activity by spinal stimulation in rat. Am J Physiol 252:R514-R525.
49. Schroder UH, Opitz T, Jager T, Sabelhaus CF, Breder J, Reymann KG (1999) Protective effect of group I metabotropic glutamate receptor activation against hypoxic/hypoglycemic injury in rat hippocampal slices: timing and involvement of protein kinase C. Neuropharmacology 38:209-216.
50. Sebastiao AM, Ribeiro JA (1996) Adenosine A2 receptor-mediated excitatory actions on the nervous system. Prog Neurobiol 48:167-189.
51. Shen E, Mo N, Dun NJ (1990) APV-sensitive dorsal root afferent transmission to neonate rat sympathetic preganglionic neurons in vitro. J Neurophysiol 64:991-999.
52. Shindou T, Mori A, Kase H, Ichimura M (2001) Adenosine A(2A) receptor enhances GABA(A)-mediated IPSCs in the rat globus pallidus. J Physiol (Lond) 532:423-434.
53. Shindou T, Nonaka H, Richardson PJ, Mori A, Kase H, Ichimura M (2002) Presynaptic adenosine A2A receptors enhance GABAergic synaptic transmission via a cyclic AMP dependent mechanism in the rat globus pallidus. Br J Pharmacol 136:296-302.
54. Simpson RE, O'Regan MH, Perkins LM, Phillis JW (1992) Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists. J Neurochem 58:1683-1690.
55. St. Lambert JH, Thomas T, Burnstock G, Spyer KM (1997) A source of adenosine involved in cardiovascular responses to defense area stimulation. Am J Physiol 272:R195-R200.
56. Strack AM, Sawyer WB, Platt KB, Loewy AD (1989) CNS cell groups regulating the sympathetic outflow to adrenal gland as revealed by transneuronal cell body labeling with pseudorabies virus. Brain Res 491:274-296.
57. Sweeney MI (1997) Neuroprotective effects of adenosine in cerebral ischemia: window of opportunity. Neurosci Biobehav Rev 21:207-217.
58. Umemiya M, Berger AJ (1994) Activation of adenosine A1 and A2 receptors differentially modulates calcium channels and glycinergic synaptic transmission in rat brainstem. Neuron 13:1439-1446.
59. Winder DG, Conn PJ (1993) Activation of metabotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine. J Neurosci 13:38-44.