Prediction of the solubility in lipidic solvent mixture: Investigation of the modeling approach and thermodynamic analysis of solubility

European Journal of Pharmaceutical Sciences

Volumn 77, Issue , 2015, Pages 161-169

  Patel, Shruti V ^a   Patel, Sarsvatkumar ^a  

^a LONG ISLAND UNIVERSITY   (United States)

Author keywords

Activity coefficient; Clotrimazole; Co solvents; Fluconazone; Lipidic solvents; Self emulsifying drug delivery system; Surfactants; Thermodynamics; Van't Hoff equation; Yalkowsky model

Indexed keywords

ACYLGLYCEROL; CLOTRIMAZOLE; DIETHYLENE GLYCOL MONOETHYL ETHER; FLUCONAZOLE; LABRASOL; MACROGOL 400; POLYSORBATE 80; PROPYLENE GLYCOL; SOLVENT; LIPID;

ARTICLE; DRUG SOLUBILITY; ENTHALPY; ENTROPY; LOGLINEAR MODEL; PHYSICAL CHEMISTRY; PREDICTIVE VALUE; PRIORITY JOURNAL; SOLVATION; THERMODYNAMICS; CHEMICAL MODEL; CHEMISTRY; SOLUBILITY; VALIDATION STUDY;

CLOTRIMAZOLE; FLUCONAZOLE; LIPIDS; MODELS, CHEMICAL; SOLUBILITY; SOLVENTS; THERMODYNAMICS;

EID: 84934935852     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.06.014     Document Type: Article

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