Analysis of relationships between solid-state properties, counterion, and developability of pharmaceutical salts

AAPS PharmSciTech

Volumn 11, Issue 3, 2010, Pages 1212-1222

  Guerrieri, Peter ^a   Rumondor, Alfred C F ^a   Li, Tonglei ^b   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

^b University of Kentucky   (United States)

Author keywords

counterion; hygroscopicity; salts; solid state; solubility

Indexed keywords

CITRIC ACID; COUNTERION; FORMIC ACID; OXALIC ACID; PHOSPHATE; PROCAINE; SODIUM;

ARTICLE; ENTHALPY; GLASS TRANSITION TEMPERATURE; LATENT STRUCTURE ANALYSIS; MELTING POINT; MULTIVARIATE ANALYSIS; NONHUMAN; PHYSICAL CHEMISTRY; PREDICTION AND FORECASTING; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SALT LOADING; SOLID STATE; SOLUBILITY; THERMODYNAMICS; WETTABILITY;

ANESTHETICS, LOCAL; COMPUTER SIMULATION; IONS; MODELS, CHEMICAL; MODELS, MOLECULAR; PHARMACEUTICAL PREPARATIONS; PHASE TRANSITION; POWDERS; PROCAINE; SALTS;

EID: 78649903986     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9499-4     Document Type: Article

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