Micronization by rapid expansion of supercritical solutions to enhance the dissolution rates of poorly water-soluble pharmaceuticals

Industrial and Engineering Chemistry Research

Volumn 39, Issue 12, 2000, Pages 4794-4802

  Charoenchaitrakool, M ^a   Dehghani, F ^a   Foster, N R ^a   Chan, H K ^b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIZATION; DISSOLUTION; DRUG PRODUCTS; ISOMERS; PHASE EQUILIBRIA; VAN DER WAALS FORCES;

MICRONIZATION; PENG-ROBINSON EQUATIONS;

SUPERCRITICAL FLUIDS;

IBUPROFEN;

CHEMICAL REACTION; CONFERENCE PAPER; DISSOLUTION; DRUG SOLUBILITY; DYNAMICS; MORPHOLOGY; PARTICLE SIZE; PHASE TRANSITION; RACEMIC MIXTURE; TEMPERATURE DEPENDENCE; ULTRASOUND;

EID: 0034387883     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie000151a     Document Type: Conference Paper

References (9)

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