Randomized comparison of next-generation sequencing and array comparative genomic hybridization for preimplantation genetic screening: A pilot study

BMC Medical Genomics

Volumn 8, Issue 1, 2015, Pages

  Yang, Zhihong ^a,b,e   Lin, James ^b   Zhang, John ^c   Fong, Wai Ieng ^d   Li, Pei ^e   Zhao, Rong ^e   Liu, Xiaohong ^e   Podevin, William ^f   Kuang, Yanping ^g   Liu, Jiaen ^e  

^a ZytoGen Global Genetics Institute   (United States)

^b Reproductive Fertility Center   (United States)

^c New Hope Fertility Center   (United States)

^d Estrada Do Visconde de Sao Januario   (China)

^e Beijing Jia En De Yun Hospital   (China)

^f Pacific Reproductive Center   (United States)

^g SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

aCGH; Aneuploidy screening; Implantation; NGS; Ongoing pregnancy; PGS

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; BLASTOCYST; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; FERTILIZATION IN VITRO; GENETIC SCREENING; GENOME ANALYSIS; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; NEXT GENERATION SEQUENCING; OUTCOME ASSESSMENT; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PILOT STUDY; PREGNANCY OUTCOME; PREGNANCY RATE; PREIMPLANTATION EMBRYO; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; COMPARATIVE STUDY; DNA MICROARRAY; HIGH THROUGHPUT SEQUENCING; IN VITRO FERTILIZATION; NIDATION; PREGNANCY; PREIMPLANTATION GENETIC DIAGNOSIS; PROCEDURES; RETROSPECTIVE STUDY;

ADULT; ANEUPLOIDY; COMPARATIVE GENOMIC HYBRIDIZATION; EMBRYO IMPLANTATION; FEMALE; FERTILIZATION IN VITRO; GENETIC TESTING; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PILOT PROJECTS; PREGNANCY; PREIMPLANTATION DIAGNOSIS; RETROSPECTIVE STUDIES;

EID: 84934907923     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/s12920-015-0110-4     Document Type: Article

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