Preimplantation genetic diagnosis increases the implantation rate in human in vitro fertilization by avoiding the transfer of chromosomally abnormal embryos

Fertility and Sterility

Volumn 68, Issue 6, 1997, Pages 1128-1131

  Gianaroli, Luca ^a   Fiorentino, Agnese ^b   Magli, M Cristina ^b   Garrisi, John ^b   Ferraretti, Anna Pia ^b   Munné, Santiago ^b  

^a Reproductive Medicine Unit   (Italy)

^b NONE

Author keywords

Aneuploidy; Assisted zona hatching; In vitro fertilization; Multicolor FISH; Poor prognosis patients; Preimplantation diagnosis; Unexplained IVF failures

Indexed keywords

ANEUPLOIDY; ARTICLE; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; DIAGNOSTIC VALUE; FERTILIZATION IN VITRO; HUMAN; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROGNOSIS; TREATMENT OUTCOME; X CHROMOSOME; Y CHROMOSOME;

ADULT; ANEUPLOIDY; BLASTOMERES; CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 21; EMBRYO IMPLANTATION; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MATERNAL AGE; PREGNANCY; PROGNOSIS; PROSPECTIVE STUDIES; SEX CHROMOSOME ABERRATIONS; TIME FACTORS;

EID: 0031468605     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(97)00412-3     Document Type: Article

References (5)

1. 1. Munné S, Lee A, Rosenwaks Z, Grifo J, Cohen J. Diagnosis of major chromosome aneuploidies in human pre-implantation embryos. Hum Reprod 1993;8:2185-91.
2. 2. Munné S, Alikani M, Tomkin G, Grifo J, Cohen J. Embryo morphology, developmental rates and maternal age are correlated with chromosomal abnormalities. Fertil Steril 1995; 64:382-91.
3. 3. Cohen J, Alikani M, Trowbridge J, Rosenwaks Z. Implantation enhancement by selective assisted hatching using zona drilling of human embryos with poor prognosis. Hum Reprod 1992;7:685-91.
4. 4. Ferraretti AP, Magli MC, Feliciani E, Montanaro N, Gianaroli L. Relationship of timing agonist administration in the cycle phase to the ovarian response to gonadotropins in the long down-regulation protocols for assisted reproductive technologies. Fertil Steril 1996;65:114-21.
5. 5. Munné S, Weier U. Simultaneous enumeration of chromosomes X, Y, 13, 18, 21 in interphase cells for pre-implantation genetic diagnosis of aneuploidy. Cytogenet Cell Genet 1997; 75:263-70.