Asiaticoside attenuates diabetes-induced cognition deficits by regulating PI3K/Akt/NF-κB pathway

Behavioural Brain Research

Volumn 292, Issue , 2015, Pages 288-299

  Yin, Zhujun ^a   Yu, Haiyang ^a   Chen, She ^a   Ma, Chunhua ^b   Ma, Xiao ^a   Xu, Lixing ^a   Ma, Zhanqiang ^a   Qu, Rong ^c   Ma, Shiping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Asiaticoside; Cognition; Diabetes; Oxidative stress; PI3K Akt NF B; Synapse

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ASIATICOSIDE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; ROSIGLITAZONE; TRITERPENE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; COGNITIVE DEFECT; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC ENCEPHALOPATHY; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MALE; MORRIS WATER MAZE TEST; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SYNAPSE; UPREGULATION; ANIMAL; COGNITION DISORDERS; COMPLICATION; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; HIPPOCAMPUS; MAZE TEST; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; COGNITION DISORDERS; DIABETES MELLITUS, EXPERIMENTAL; HIPPOCAMPUS; INFLAMMATION; MALE; MAZE LEARNING; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRITERPENES;

EID: 84934783539     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2015.06.024     Document Type: Article

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