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Volumn 670, Issue , 2011, Pages 71-84

Measuring APP carboxy-terminal fragments

Author keywords

Alzheimer's disease; Amyloid precursor protein; APP C terminal fragments; A ; BACE; Western blot

Indexed keywords

ACETIC ACID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; ANTIBODY; PEPTIDE FRAGMENT; UREA;

EID: 84934444280     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60761-744-0_6     Document Type: Article
Times cited : (1)

References (12)
  • 1
    • 1442264828 scopus 로고    scopus 로고
    • Take five - BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation
    • Haass, C. (2004) Take five - BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation. EMBO J. 23, 483-8.
    • (2004) EMBO J , vol.23 , pp. 483-488
    • Haass, C.1
  • 2
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's disease amyloid hypo thesis: A genetic perspective
    • Tanzi, R., and Bertram, L. (2005) Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective. Cell 120, 545-55.
    • (2005) Cell , vol.120 , pp. 545-555
    • Tanzi, R.1    Bertram, L.2
  • 3
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe, D. J. (2001) Alzheimer's disease: Genes, proteins, and therapy. Physiol. Rev. 81, 741-66.
    • (2001) Physiol. Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 5
    • 13844265969 scopus 로고    scopus 로고
    • BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo
    • Lee, E. B., Zhang, B., Liu, K., Greenbaum, E. A., Doms, R. W., Trojanowski, J. Q., and Lee, V. M. (2005) BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo. J. Cell Biol. 168, 291-302.
    • (2005) J. Cell Biol , vol.168 , pp. 291-302
    • Lee, E.B.1    Zhang, B.2    Liu, K.3    Greenbaum, E.A.4    Doms, R.W.5    Trojanowski, J.Q.6    Lee, V.M.7
  • 7
    • 16244416174 scopus 로고    scopus 로고
    • A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model
    • Lim, G. P., Calon, F., Morihara, T., Yang, F., Teter, B., Ubeda, O., Salem, N., Jr., Frautschy, S. A., and Cole, G. M. (2005) A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model. J. Neurosci. 25, 3032-40.
    • (2005) J. Neurosci , vol.25 , pp. 3032-3040
    • Lim, G.P.1    Calon, F.2    Morihara, T.3    Yang, F.4    Teter, B.5    Ubeda, O.6    Salem Jr., N.7    Frautschy, S.A.8    Cole, G.M.9
  • 8
    • 33845991184 scopus 로고    scopus 로고
    • Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain
    • Sano, Y., Syuzo-Takabatake, A., Nakaya, T., Saito, Y., Tomita, S., Itohara, S., and Suzuki, T. (2006) Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. J. Biol. Chem. 281, 37853-60.
    • (2006) J. Biol. Chem , vol.281 , pp. 37853-37860
    • Sano, Y.1    Syuzo-Takabatake, A.2    Nakaya, T.3    Saito, Y.4    Tomita, S.5    Itohara, S.6    Suzuki, T.7
  • 9
    • 0034213718 scopus 로고    scopus 로고
    • High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
    • Mucke, L., Masliah, E., Yu, G.-Q., Mallory, M., Rockenstein, E. M., Tatsuno, G., Hu, K., Kholodenko, D., Johnson-Wood, K., and McConlogue, L. (2000) High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation. J. Neurosci. 20, 4050-58.
    • (2000) J. Neurosci , vol.20 , pp. 4050-4058
    • Mucke, L.1    Masliah, E.2    Yu, G.-Q.3    Mallory, M.4    Rockenstein, E.M.5    Tatsuno, G.6    Hu, K.7    Kholodenko, D.8    Johnson-Wood, K.9    McConlogue, L.10
  • 10
    • 25444479179 scopus 로고    scopus 로고
    • High β-Secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-β levels: Implications for the treatment of Alzheimer's disease
    • Rockenstein, E., Mante, M., Alford, M., Adame, A., Crews, L., Hashimoto, M., Esposito, L., Mucke, L., and Masliah, E. (2005) High β-Secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-β levels: Implications for the treatment of Alzheimer's disease. J. Biol. Chem. 280, 32957-67.
    • (2005) J. Biol. Chem , vol.280 , pp. 32957-32967
    • Rockenstein, E.1    Mante, M.2    Alford, M.3    Adame, A.4    Crews, L.5    Hashimoto, M.6    Esposito, L.7    Mucke, L.8    Masliah, E.9
  • 11
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
    • DeMattos, R. B., Bales, K. R., Cummins, D. J., Dodart, J.-C., Paul, S. M., and Holtzman, D. M. (2001) Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 98, 8850-55.
    • (2001) Proc. Natl. Acad. Sci. U.S.A , vol.98 , pp. 8850-8855
    • Demattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Dodart, J.-C.4    Paul, S.M.5    Holtzman, D.M.6
  • 12
    • 10644290831 scopus 로고    scopus 로고
    • Intracellulary generated Aβ counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells
    • Esposito, L., Gan, L., Yu, G.-Q., Essrich, C., and Mucke, L. (2004) Intracellulary generated Aβ counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells. J. Neurochem. 91, 1260-74.
    • (2004) J. Neurochem , vol.91 , pp. 1260-1274
    • Esposito, L.1    Gan, L.2    Yu, G.-Q.3    Essrich, C.4    Mucke, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.