Treating diet-induced diabetes and obesity with human embryonic stem cell-derived pancreatic progenitor cells and antidiabetic drugs

Stem Cell Reports

Volumn 4, Issue 4, 2015, Pages 605-620

  Bruin, Jennifer E ^a   Saber, Nelly ^a   Braun, Natalie ^a   Fox, Jeßica K ^a   Mojibian, Majid ^a   Asadi, Ali ^a   Drohan, Campbell ^a   O'Dwyer, Shannon ^a   Rosman Balzer, Diana S ^b   Swiß, Victoria A ^b   Rezania, Alireza ^b   Kieffer, Timothy J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

METFORMIN; ROSIGLITAZONE; SITAGLIPTIN; ANTIDIABETIC AGENT; GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; EMBRYONIC STEM CELL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HYPERGLYCEMIA; INSULIN RESISTANCE; LIPID DIET; LIVER WEIGHT; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PANCREATIC PROGENITOR CELL; PHENOTYPE; PRIORITY JOURNAL; STEM CELL; STEM CELL TRANSPLANTATION; ADVERSE EFFECTS; ANATOMY AND HISTOLOGY; ANIMAL; BIOLOGICAL THERAPY; CELL DIFFERENTIATION; CYTOLOGY; DIABETES MELLITUS, TYPE 2; DIET; DISEASE MODEL; GENE EXPRESSION PROFILING; HUMAN; HUMAN EMBRYONIC STEM CELL; LIVER; METABOLISM; ORGAN SIZE; PANCREAS; PANCREAS ISLET; SCID MOUSE;

MUS;

ANIMALS; CELL DIFFERENTIATION; CELL- AND TISSUE-BASED THERAPY; DIABETES MELLITUS, TYPE 2; DIET; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GLUCOSE; HUMAN EMBRYONIC STEM CELLS; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; LIVER; MICE; MICE, SCID; OBESITY; ORGAN SIZE; PANCREAS; PHENOTYPE; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 84933676295     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2015.02.011     Document Type: Article

References (40)

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