Influence of a high-fat diet during chronic hyperglycemia on β-cell function in pancreatic islet transplants to streptozotocin-diabetic rats

European Journal of Endocrinology

Volumn 144, Issue 5, 2001, Pages 521-527

  Hiramatsu, Shinsuke ^a   Grill, Valdemar ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; FATTY ACID; GLUCOSE; INSULIN; MESSENGER RNA; PREPROINSULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHRONIC DISEASE; CLINICAL PROTOCOL; DIET RESTRICTION; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INNER CELL MASS; INSULIN RELEASE; INSULIN RESPONSE; INSULIN SYNTHESIS; ISOGRAFT; ISOLATION PROCEDURE; KIDNEY CAPSULE; LIPID DIET; LOW FAT DIET; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PANCREAS ISLET TRANSPLANTATION; PERFUSION; PRIORITY JOURNAL; RAT; RECIPIENT; STREPTOZOCIN DIABETES;

EID: 0035006255     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1440521     Document Type: Article

References (30)

1. Yki-Jarvinen H. Glucose toxicity. Endocrine Reviews 1992 13 415-431.
2. Leahy JL, Bonner-Weir S & Weir GC. Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion. Diabetes Care 1992 15 442-455.
3. Grill V & Björklund A. Dysfunctional insulin secretion in type 2 diabetes: role of metabolic abnormalities. Cellular and Molecular Life Sciences 2000 57 429-440.
4. Sako Y & Grill V. A 48-h lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and β cell oxidation through a process likely coupled to fatty acid oxidation. Endocrinology 1990 127 1580-1589.
5. Zhou YP & Grill V. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. Journal of Clinical Investigation 1994 93 870-876.
6. Capito K, Hansen SE, Hedeskov CJ, Islin H & Thams P. Fat-induced changes in mouse pancreatic insulin secretion, insulin biosynthesis and glucose metabolism. Acta Diabetologica 1992 28 193-198.
7. Lee Y, Hirose H, Ohneda M, Johnson J, McGarry D & Unger R. Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. PNAS 1994 91 10878-10882.
8. Zhou YP & Grill V. A fatty acid induced decrease in pyruvate dehydrogenase activity is an important determinant of β-cell dysfunction in the obese diabetic db/db mouse. Diabetes 1996 45 580-586.
9. Shimabukuro M, Zhou YT, Levi M & Unger RH. Fatty acid-induced β cell apoptosis: a link between obesity and diabetes. PNAS 1998 95 2498-2502.
10. Zhou YP & Grill V. Long term exposure to fatty acids and ketones inhibits β-cell functions in human pancreatic islets of Langerhans. Journal of Clinical Endocrinology and Metabolism 1995 80 1584-1590.
11. Hiramatsu S, Nishimura J & Grill V. Effects associated with high fat diet on insulin secretion and biosynthesis in pancreatic islet transplants to diabetic rats: no evidence for 'lipotoxicity'. Diabetes (Suppl) 2000 49 A61.
12. Lacy PE & Kostianovsky M. Method for the isolation of intact islets of Langerhans from the pancreas. Diabetes 1967 16 35-59.
13. Inoue K, Cetkovic-Cvrlje M, Eizirik DL & Grill V. Irreversible loss of normal beta-cell regulation by glucose in neonatally streptozotocin diabetic rats. Diabetologia 1994 37 351-357.
14. Inoue K, Norgren S, Luthman H, Möller C & Grill V. β cell of aging rats: impaired stimulus-secretion coupling but normal susceptibility to adverse effects of a diabetic state. Metabolism 1997 46 242-246.
15. Grill V & Efendic S. Loss of a priming effect of glucose on A-and D-cell secretion in perfused pancreas from alloxan diabetic rats: role of insulin and alloxan. Diabetologia 1983 24 47-51.
16. Herbert V, Lau KS, Gottlieb CW & Bleicher SJ. Coated charcoal immunoassay of insulin. Journal of Clinical Endocrinology and Metabolism 1965 25 1375-1384.
17. Chomczynski P & Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 1987 162 156-159.
18. Tajiri Y, Möller C & Grill V. Long term effects of aminoguanidine on insulin release and biosynthesis: evidence that the formation of advanced glycosylation end products inhibits β cell function. Endocrinology 1996 138 273-280.
19. Chavez M, Seeley RJ, Havel PJ, Friedman MI, Matson CA, Woods SC et al. Effect of high-fat diet on food intake and hypothalamic neuropeptide gene expression in streptozotocin diabetes. Journal of Clinical Investigation 1998 102 340-346.
20. Montana E, Bonner-Weir S & Weir GC. Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozotocin diabetic C57BL/6 mice. Journal of Clinical Investigation 1993 91 780-787.
21. Bollheimer LC, Skelly RH, Chester MW, McGarry JD & Rhodes CJ. Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increased basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. Journal of Clinical Investigation 1998 101 1094-1101.
22. Milburn JL, Hirose H, Lee YH, Nagasawa Y, Ogawa A, Ohneda M et al. Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acid. Journal of Biological Chemistry 1995 270 1295-1299.
23. Higa M, Zhou YT, Ravazzola M, Baetens D, Orci L & Unger RH. Troglitazone prevents mitochondrial alterations β cell destruction, and diabetes in obese prediabetic rats. PNAS 1999 96 11513-11518.
24. Crespin SR, Greenough WB & Steinbergh D. Stimulation of insulin secretion by long-chain free fatty acids, a direct pancreatic effect. Journal of Clinical Investigation 1973 52 1979-1984.
25. Balasse EO & Ooms HA. Role of plasma free fatty acids in the control of insulin secretion in man. Diabetologia 1973 9 145-151.
26. Malaisse W & Malaisse-Lagae F. Stimulation of insulin secretion by non-carbohydrate metabolites. Journal of Laboratory and Clinical Medicine 1968 72 438-448.
27. Warnotte C, Gilon P, Nenquin M & Henquin JC. Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells. Diabetes 1994 43 703-711.
28. Marynissen G, Leclercq-Myer V, Sener A & Malaisse W. Perturbation of pancreatic islet function in glucose-infused rats. Metabolism 1990 39 87-95.
29. Kim Y, Iwashita S, Tamura T, Tokuyama K & Suzuki M. Effect of high-fat diet on the gene expression of pancreatic GLUT2 and glucokinase in rats. Biochemical and Biophysical Research Communications 1995 208 1092-1098.
30. Ohneda M, Inman L & Unger R. Caloric restriction in obese pre-diabetic rats prevents beta cell depletion, loss of GLUT 2 and glucose incompetence. Diabetologia 1995 38 173-179.