-
1
-
-
83255189758
-
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
-
Amps K., et al. Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat. Biotechnol. 2011, 29(12):1132-1144.
-
(2011)
Nat. Biotechnol.
, vol.29
, Issue.12
, pp. 1132-1144
-
-
Amps, K.1
-
2
-
-
84856696056
-
The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells
-
Basford C.L., et al. The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells. Diabetologia 2012, 55(2):358-371.
-
(2012)
Diabetologia
, vol.55
, Issue.2
, pp. 358-371
-
-
Basford, C.L.1
-
3
-
-
79958090845
-
A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3
-
Bone H.K., et al. A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. J. Cell Sci. 2011, 124(Pt 12):1992-2000.
-
(2011)
J. Cell Sci.
, vol.124
, Issue.PART 12
, pp. 1992-2000
-
-
Bone, H.K.1
-
4
-
-
24944591025
-
New sources of pancreatic beta-cells
-
Bonner-Weir S., Weir G.C. New sources of pancreatic beta-cells. Nat. Biotechnol. 2005, 23(7):857-861.
-
(2005)
Nat. Biotechnol.
, vol.23
, Issue.7
, pp. 857-861
-
-
Bonner-Weir, S.1
Weir, G.C.2
-
6
-
-
84881614603
-
Maturation and function of human embryonic stem cell-derived pancreatic progenitors in macroencapsulation devices following transplant into mice
-
Bruin J.E., et al. Maturation and function of human embryonic stem cell-derived pancreatic progenitors in macroencapsulation devices following transplant into mice. Diabetologia 2013, 56(9):1987-1998.
-
(2013)
Diabetologia
, vol.56
, Issue.9
, pp. 1987-1998
-
-
Bruin, J.E.1
-
7
-
-
77950364568
-
Generation of homogeneous PDX1(+) pancreatic progenitors from human ES cell-derived endoderm cells
-
Cai J., et al. Generation of homogeneous PDX1(+) pancreatic progenitors from human ES cell-derived endoderm cells. J. Mol. Cell Biol. 2010, 2(1):50-60.
-
(2010)
J. Mol. Cell Biol.
, vol.2
, Issue.1
, pp. 50-60
-
-
Cai, J.1
-
8
-
-
84896408317
-
A human embryonic stem cell line adapted for high throughput screening
-
Caron N.J., et al. A human embryonic stem cell line adapted for high throughput screening. Biotech. Bioeng. 2013, 110(10):2706-2716.
-
(2013)
Biotech. Bioeng.
, vol.110
, Issue.10
, pp. 2706-2716
-
-
Caron, N.J.1
-
9
-
-
62649138086
-
A small molecule that directs differentiation of human ESCs into the pancreatic lineage
-
Chen S., et al. A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat. Chem. Biol. 2009, 5(4):258-265.
-
(2009)
Nat. Chem. Biol.
, vol.5
, Issue.4
, pp. 258-265
-
-
Chen, S.1
-
10
-
-
80855124208
-
Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals
-
Coppieters K.T., et al. Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals. Diabetes Metab. Res. Rev. 2011, 27(8):746-754.
-
(2011)
Diabetes Metab. Res. Rev.
, vol.27
, Issue.8
, pp. 746-754
-
-
Coppieters, K.T.1
-
11
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour K.A., et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 2006, 24(11):1392-1401.
-
(2006)
Nat. Biotechnol.
, vol.24
, Issue.11
, pp. 1392-1401
-
-
D'Amour, K.A.1
-
12
-
-
0028859374
-
Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression
-
De Vos A., et al. Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression. J. Clin. Invest. 1995, 96(5):2489-2495.
-
(1995)
J. Clin. Invest.
, vol.96
, Issue.5
, pp. 2489-2495
-
-
De Vos, A.1
-
13
-
-
1842844414
-
Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications
-
Donath M.Y., Halban P.A. Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications. Diabetologia 2004, 47(3):581-589.
-
(2004)
Diabetologia
, vol.47
, Issue.3
, pp. 581-589
-
-
Donath, M.Y.1
Halban, P.A.2
-
14
-
-
24944471393
-
Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal K(ATP)
-
Flagg T.P., et al. Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal K(ATP). J. Mol. Cell. Cardiol. 2005, 39(4):647-656.
-
(2005)
J. Mol. Cell. Cardiol.
, vol.39
, Issue.4
, pp. 647-656
-
-
Flagg, T.P.1
-
15
-
-
0023039491
-
Development of human pancreas. Immunohistochemical study of fetal pancreatic secretory proteins
-
Fukayama M., et al. Development of human pancreas. Immunohistochemical study of fetal pancreatic secretory proteins. Differ.; Res. Biol. Divers. 1986, 31(2):127-133.
-
(1986)
Differ.; Res. Biol. Divers.
, vol.31
, Issue.2
, pp. 127-133
-
-
Fukayama, M.1
-
16
-
-
0032488981
-
Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2
-
Furuta M., et al. Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2. J. Biol. Chem. 1998, 273(6):3431-3437.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.6
, pp. 3431-3437
-
-
Furuta, M.1
-
17
-
-
65649109022
-
Stem cells to pancreatic beta-cells: new sources for diabetes cell therapy
-
Guo T., Hebrok M. Stem cells to pancreatic beta-cells: new sources for diabetes cell therapy. Endocr. Rev. 2009, 30(3):214-227.
-
(2009)
Endocr. Rev.
, vol.30
, Issue.3
, pp. 214-227
-
-
Guo, T.1
Hebrok, M.2
-
18
-
-
34547857040
-
Generation of insulin-producing islet-like clusters from human embryonic stem cells
-
Jiang J., et al. Generation of insulin-producing islet-like clusters from human embryonic stem cells. Stem Cells 2007, 25(8):1940-1953.
-
(2007)
Stem Cells
, vol.25
, Issue.8
, pp. 1940-1953
-
-
Jiang, J.1
-
19
-
-
34247353657
-
In vitro derivation of functional insulin-producing cells from human embryonic stem cells
-
Jiang W., et al. In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res. 2007, 17(4):333-344.
-
(2007)
Cell Res.
, vol.17
, Issue.4
, pp. 333-344
-
-
Jiang, W.1
-
20
-
-
33847217554
-
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
-
Johansson K.A., et al. Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev. Cell 2007, 12(3):457-465.
-
(2007)
Dev. Cell
, vol.12
, Issue.3
, pp. 457-465
-
-
Johansson, K.A.1
-
21
-
-
79961175124
-
Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells
-
Kelly O.G., et al. Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells. Nat. Biotechnol. 2011, 29(8):750-756.
-
(2011)
Nat. Biotechnol.
, vol.29
, Issue.8
, pp. 750-756
-
-
Kelly, O.G.1
-
22
-
-
66049101025
-
Cyp26 enzymes function in endoderm to regulate pancreatic field size
-
Kinkel M.D., et al. Cyp26 enzymes function in endoderm to regulate pancreatic field size. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(19):7864-7869.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, Issue.19
, pp. 7864-7869
-
-
Kinkel, M.D.1
-
23
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
Kroon E., et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 2008, 26(4):443-452.
-
(2008)
Nat. Biotechnol.
, vol.26
, Issue.4
, pp. 443-452
-
-
Kroon, E.1
-
24
-
-
84881444781
-
Decomposition of slide helix contributions to ATP-dependent inhibition of Kir6.2 channels
-
Li J.B., et al. Decomposition of slide helix contributions to ATP-dependent inhibition of Kir6.2 channels. J. Biol. Chem. 2013, 288(32):23038-23049.
-
(2013)
J. Biol. Chem.
, vol.288
, Issue.32
, pp. 23038-23049
-
-
Li, J.B.1
-
26
-
-
0035856952
-
Beta-Cell death during progression to diabetes
-
Mathis D., Vence L., Benoist C. beta-Cell death during progression to diabetes. Nature 2001, 414(6865):792-798.
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
27
-
-
77952682209
-
Noggin, retinoids, and fibroblast growth factor regulate hepatic or pancreatic fate of human embryonic stem cells
-
(2245 e1-14)
-
Mfopou J.K., et al. Noggin, retinoids, and fibroblast growth factor regulate hepatic or pancreatic fate of human embryonic stem cells. Gastroenterology 2010, 138(7):2233-2245. (2245 e1-14).
-
(2010)
Gastroenterology
, vol.138
, Issue.7
, pp. 2233-2245
-
-
Mfopou, J.K.1
-
28
-
-
79551580013
-
Stage-specific signaling through TGFbeta family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells
-
Nostro M.C., et al. Stage-specific signaling through TGFbeta family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development 2011, 138(5):861-871.
-
(2011)
Development
, vol.138
, Issue.5
, pp. 861-871
-
-
Nostro, M.C.1
-
29
-
-
50949102657
-
Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells
-
Ostrom M., et al. Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells. PLoS ONE 2008, 3(7):e2841.
-
(2008)
PLoS ONE
, vol.3
, Issue.7
-
-
Ostrom, M.1
-
30
-
-
78751502673
-
Production of functional glucagon-secreting alpha-cells from human embryonic stem cells
-
Rezania A., et al. Production of functional glucagon-secreting alpha-cells from human embryonic stem cells. Diabetes 2011, 60(1):239-247.
-
(2011)
Diabetes
, vol.60
, Issue.1
, pp. 239-247
-
-
Rezania, A.1
-
31
-
-
84864390303
-
Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice
-
Rezania A., et al. Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice. Diabetes 2012, 61(8):2016-2029.
-
(2012)
Diabetes
, vol.61
, Issue.8
, pp. 2016-2029
-
-
Rezania, A.1
-
32
-
-
84887940137
-
Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo
-
(Epub ahead of print)
-
Rezania A., et al. Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo. Stem Cells 2013, (Epub ahead of print). 10.1002/stem.1489.
-
(2013)
Stem Cells
-
-
Rezania, A.1
-
33
-
-
84856715292
-
Immunohistochemical characterization of insulin/glucagon co-expressing cells in the developing human pancreas
-
Riedel M.J., et al. Immunohistochemical characterization of insulin/glucagon co-expressing cells in the developing human pancreas. Diabetologia 2011, 55(2):372-381.
-
(2011)
Diabetologia
, vol.55
, Issue.2
, pp. 372-381
-
-
Riedel, M.J.1
-
34
-
-
77953598030
-
Assessing differentiation status of human embryonic stem cells noninvasively using Raman microspectroscopy
-
Schulze H.G., et al. Assessing differentiation status of human embryonic stem cells noninvasively using Raman microspectroscopy. Anal. Chem. 2010, 82(12):5020-5027.
-
(2010)
Anal. Chem.
, vol.82
, Issue.12
, pp. 5020-5027
-
-
Schulze, H.G.1
-
35
-
-
84870314365
-
Restoring insulin production for type 1 diabetes
-
Tuduri E., Bruin J.E., Kieffer T.J. Restoring insulin production for type 1 diabetes. J. Diabetes 2012, 4(4):319-331.
-
(2012)
J. Diabetes
, vol.4
, Issue.4
, pp. 319-331
-
-
Tuduri, E.1
Bruin, J.E.2
Kieffer, T.J.3
-
36
-
-
80755187146
-
Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells
-
Xu X., Browning V.L., Odorico J.S. Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells. Mech. Dev. 2011, 128(7-10):412-427.
-
(2011)
Mech. Dev.
, vol.128
, Issue.7-10
, pp. 412-427
-
-
Xu, X.1
Browning, V.L.2
Odorico, J.S.3
-
37
-
-
0036678101
-
Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3
-
Zhu X., et al. Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3. Proc. Natl. Acad. Sci. U. S. A. 2002, 99(16):10299-10304.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, Issue.16
, pp. 10299-10304
-
-
Zhu, X.1
|