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Volumn 35, Issue 14, 2016, Pages 1811-1821

PML is required for telomere stability in non-neoplastic human cells

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN RETINOIC ACID RECEPTOR ALPHA FUSION PROTEIN; RETINOIC ACID RECEPTOR ALPHA; UNCLASSIFIED DRUG; NUCLEAR PROTEIN; ONCOPROTEIN; PML PROTEIN, HUMAN; RARA PROTEIN, HUMAN; RARA PROTEIN, MOUSE; RETINOIC ACID RECEPTOR; TELOMERASE; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

EID: 84933575664     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.246     Document Type: Article
Times cited : (23)

References (62)
  • 1
    • 34249820255 scopus 로고    scopus 로고
    • Telomerase in T lymphocytes use it and lose it?
    • Akbar AN, Vukmanovic-Stejic M. Telomerase in T lymphocytes: use it and lose it? J Immunol 2007; 178: 6689-6694
    • (2007) J Immunol , vol.178 , pp. 6689-6694
    • Akbar, A.N.1    Vukmanovic-Stejic, M.2
  • 2
    • 0033592950 scopus 로고    scopus 로고
    • DNA doublestrand break repair proteins are required to cap the ends of mammalian chromosomes
    • Bailey SM, Meyne J, Chen DJ, Kurimasa A, Li GC, Lehnert BE et al. DNA doublestrand break repair proteins are required to cap the ends of mammalian chromosomes. Proc Nati Acad Sci USA 1999; 96: 14899-14904
    • (1999) Proc Nati Acad Sci USA , vol.96 , pp. 14899-14904
    • Bailey, S.M.1    Meyne, J.2    Chen, D.J.3    Kurimasa, A.4    Li, G.C.5    Lehnert, B.E.6
  • 3
    • 84872912456 scopus 로고    scopus 로고
    • Finding the end: Recruitment of telomerase to telomeres
    • Nandakumar J, Cech TR. Finding the end: recruitment of telomerase to telomeres. Nat Rev Mol Cell Biol 2013; 14: 69-82
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 69-82
    • Nandakumar, J.1    Cech, T.R.2
  • 5
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • Takai H, Smogorzewska A, de Lange T. DNA damage foci at dysfunctional telomeres. Curr Biol 2003; 13: 1549-1556
    • (2003) Curr Biol , vol.13 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    De Lange, T.3
  • 7
    • 0037192462 scopus 로고    scopus 로고
    • Senescence induced by altered telomere state, not telomere loss
    • Karlseder J, Smogorzewska A. de Lange T. Senescence induced by altered telomere state, not telomere loss. Science 2002; 295: 2446-2449
    • (2002) Science , vol.295 , pp. 2446-2449
    • Karlseder, J.1    Smogorzewska, A.2    De Lange, T.3
  • 8
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25: 585-621
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 9
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990; 345: 458-460
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 12
    • 84874611617 scopus 로고    scopus 로고
    • Telomeres and age-related disease: How telomere biology informs clinical paradigms
    • Armanios M. Telomeres and age-related disease: how telomere biology informs clinical paradigms. J Clin Invest 2013; 123: 996-1002
    • (2013) J Clin Invest , vol.123 , pp. 996-1002
    • Armanios, M.1
  • 13
    • 84874599388 scopus 로고    scopus 로고
    • Coming of age: Molecular drivers of aging and therapeutic opportunities
    • Newgard CB, Sharpless NE. Coming of age: molecular drivers of aging and therapeutic opportunities. J Clin Invest 2013; 123: 946-950
    • (2013) J Clin Invest , vol.123 , pp. 946-950
    • Newgard, C.B.1    Sharpless, N.E.2
  • 14
    • 84901288438 scopus 로고    scopus 로고
    • The role of senescent cells in ageing
    • van Deursen JM. The role of senescent cells in ageing. Nature 2014; 509: 439-446
    • (2014) Nature , vol.509 , pp. 439-446
    • Van Deursen, J.M.1
  • 15
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985; 43: 405-413
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 16
    • 33646505742 scopus 로고    scopus 로고
    • Telomerase regulation and stem cell behaviour
    • Flores I, Benetti R, Blasco MA. Telomerase regulation and stem cell behaviour. Curr Opin Cell Biol 2006; 18: 254-260
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 254-260
    • Flores, I.1    Benetti, R.2    Ma, B.3
  • 17
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011-2015
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Ma, P.2    Prowse, K.R.3    Harley, C.B.4    West, M.D.5    Ho, P.L.6
  • 18
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
    • Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 1997; 3: 1271-1274
    • (1997) Nat Med , vol.3 , pp. 1271-1274
    • Bryan, T.M.1    Englezou, A.2    Dalla-Pozza, L.3    Ma, D.4    Reddel, R.R.5
  • 19
    • 77951133257 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres: Models, mechanisms and implications
    • Cesare AJ, Reddel RR. Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 2010; 11: 319-330
    • (2010) Nat Rev Genet , vol.11 , pp. 319-330
    • Cesare, A.J.1    Reddel, R.R.2
  • 20
    • 0033199695 scopus 로고    scopus 로고
    • Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body
    • Yeager TR, Neumann AA, Englezou A, Huschtscha LI, Noble JR, Reddel RR. Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res 1999; 59: 4175-4179
    • (1999) Cancer Res , vol.59 , pp. 4175-4179
    • Yeager, T.R.1    Neumann, A.A.2    Englezou, A.3    Huschtscha, L.I.4    Noble, J.R.5    Reddel, R.R.6
  • 21
    • 0025917413 scopus 로고
    • Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties
    • Pandolfi PP, Grignani F, Alcalay M, Mencarelli A, Biondi A, LoCoco F et al. Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties. Oncogene 1991; 6: 1285-1292
    • (1991) Oncogene , vol.6 , pp. 1285-1292
    • Pandolfi, P.P.1    Grignani, F.2    Alcalay, M.3    Mencarelli, A.4    Biondi, A.5    LoCoco, F.6
  • 22
    • 0025875679 scopus 로고
    • The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
    • de The H, Lavau C, Marchio A, Chomienne C, Degos L, Dejean A. The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 1991; 66: 675-684
    • (1991) Cell , vol.66 , pp. 675-684
    • De The, H.1    Lavau, C.2    Marchio, A.3    Chomienne, C.4    Degos, L.5    Dejean, A.6
  • 23
    • 0025780876 scopus 로고
    • Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor
    • Kakizuka A, Miller Jr WH, Umesono K, Warrell Jr RP, Frankel SR, Murty VV et al. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 1991; 66: 663-674
    • (1991) PML. Cell , vol.66 , pp. 663-674
    • Kakizuka, A.1    Miller, W.H.2    Umesono, K.3    Warrell, R.P.4    Frankel, S.R.5    Murty, V.V.6
  • 24
    • 0026326963 scopus 로고
    • Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia
    • Goddard AD, Borrow J, Freemont PS, Solomon E. Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia. Science 1991; 254: 1371-1374
    • (1991) Science , vol.254 , pp. 1371-1374
    • Goddard, A.D.1    Borrow, J.2    Freemont, P.S.3    Solomon, E.4
  • 25
    • 84865074686 scopus 로고    scopus 로고
    • The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies
    • de The H, Le Bras M, Lallemand-Breitenbach V. The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies. J Cell Biol 2012; 198: 11-21
    • (2012) J Cell Biol , vol.198 , pp. 11-21
    • De The, H.1    Le Bras, M.2    Lallemand-Breitenbach, V.3
  • 26
    • 0035969104 scopus 로고    scopus 로고
    • PML interaction with p53 and its role in apoptosis and replicative senescence
    • Pearson M, Pelicci PG., PML interaction with p53 and its role in apoptosis and replicative senescence. Oncogene, 2001 20. 7250-7256.
    • (2001) Oncogene , Issue.20 , pp. 7250-7256
    • Pearson, M.1    Pelicci, P.G.2
  • 27
    • 0037034829 scopus 로고    scopus 로고
    • PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage
    • Carbone R, Pearson M, Minucci S, Pelicci PG. PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage. Oncogene 2002; 21: 1633-1640
    • (2002) Oncogene , vol.21 , pp. 1633-1640
    • Carbone, R.1    Pearson, M.2    Minucci, S.3    Pelicci, P.G.4
  • 28
    • 33749547681 scopus 로고    scopus 로고
    • Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR
    • Dellaire G, Ching RW, Ahmed K, Jalali F, Tse KC, Bristow RG et al. Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR. J Cell Biol 2006; 175: 55-66
    • (2006) J Cell Biol , vol.175 , pp. 55-66
    • Dellaire, G.1    Ching, R.W.2    Ahmed, K.3    Jalali, F.4    Tse, K.C.5    Bristow, R.G.6
  • 29
    • 0037169341 scopus 로고    scopus 로고
    • The role of PML in tumor suppression
    • Salomoni P, Pandolfi PP. The role of PML in tumor suppression. Cell 2002; 108: 165-170
    • (2002) Cell , vol.108 , pp. 165-170
    • Salomoni, P.1    Pandolfi, P.P.2
  • 30
    • 84891107383 scopus 로고    scopus 로고
    • Is PML a tumor suppressor?
    • Mazza M, Pelicci PG. Is PML a tumor suppressor? Front Oncol 2013; 3: 174
    • (2013) Front Oncol , vol.3 , pp. 174
    • Mazza, M.1    Pelicci, P.G.2
  • 31
    • 84856063743 scopus 로고    scopus 로고
    • The alternative lengthening of telomeres pathway may operate in non-neoplastic human cells
    • Slatter TL, Tan X, Yuen YC, Gunningham S, Ma SS, Daly E et al. The alternative lengthening of telomeres pathway may operate in non-neoplastic human cells. J Phatol 2012; 226: 509-518
    • (2012) J Phatol , vol.226 , pp. 509-518
    • Slatter, T.L.1    Tan, X.2    Yuen, Y.C.3    Gunningham, S.4    Ma, S.S.5    Daly, E.6
  • 32
    • 84877283370 scopus 로고    scopus 로고
    • PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells
    • Chang FT, McGhie JD, Chan FL, Tang MC, Anderson MA, Mann JR et al. PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells. Nucleic Acids Res 2013; 41: 4447-4458
    • (2013) Nucleic Acids Res , vol.41 , pp. 4447-4458
    • Chang, F.T.1    McGhie, J.D.2    Chan, F.L.3    Tang, M.C.4    Ma, A.5    Mann, J.R.6
  • 33
    • 0025043959 scopus 로고
    • The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus
    • de The H, Chomienne C, Lanotte M, Degos L, Dejean A. The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus. Nature 1990; 347: 558-561
    • (1990) Nature , vol.347 , pp. 558-561
    • De The, H.1    Chomienne, C.2    Lanotte, M.3    Degos, L.4    Dejean, A.5
  • 34
    • 0033561797 scopus 로고    scopus 로고
    • Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
    • Melnick A, Licht JD. Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 1999; 93: 3167-3215
    • (1999) Blood , vol.93 , pp. 3167-3215
    • Melnick, A.1    Licht, J.D.2
  • 35
    • 84873319024 scopus 로고    scopus 로고
    • The role of telomeres in stem cells and cancer
    • Gunes C, Rudolph KL. The role of telomeres in stem cells and cancer. Cell 2013; 152: 390-393
    • (2013) Cell , vol.152 , pp. 390-393
    • Gunes, C.1    Rudolph, K.L.2
  • 36
    • 84875511303 scopus 로고    scopus 로고
    • A computational platform for robotized fluorescence microscopy I: High-content image-based cell-cycle analysis
    • Furia L, Pelicci PG, Faretta M. A computational platform for robotized fluorescence microscopy (I): high-content image-based cell-cycle analysis. Cytometry A 2013; 83: 333-343
    • (2013) Cytometry A , vol.83 , pp. 333-343
    • Furia, L.1    Pelicci, P.G.2    Faretta, M.3
  • 37
    • 84875519987 scopus 로고    scopus 로고
    • A computational platform for robotized fluorescence microscopy (II): DNA damage, replication, checkpoint activation, and cell cycle progression by high-content high-resolution multiparameter image-cytometry
    • Furia L, Pelicci PG, Faretta M. A computational platform for robotized fluorescence microscopy (II): DNA damage, replication, checkpoint activation, and cell cycle progression by high-content high-resolution multiparameter image-cytometry. Cytometry A 2013; 83: 344-355
    • (2013) Cytometry A , vol.83 , pp. 344-355
    • Furia, L.1    Pelicci, P.G.2    Faretta, M.3
  • 38
    • 6944239985 scopus 로고    scopus 로고
    • Biological activity of the G-quadruplex ligand RHPS4 3, 11-difluoro-6 8, 13-trimethyl-8Hquino[ 4, 3, 2-kl]acridinium methosulfate) is associated with telomere capping alteration
    • Leonetti C, Amodei S, D'Angelo C, Rizzo A, Benassi B, Antonelli A et al. Biological activity of the G-quadruplex ligand RHPS4 (3, 11-difluoro-6, 8, 13-trimethyl-8Hquino[ 4, 3, 2-kl]acridinium methosulfate) is associated with telomere capping alteration. Mol Pharmacol 2004; 66: 1138-1146
    • (2004) Mol Pharmacol , vol.66 , pp. 1138-1146
    • Leonetti, C.1    Amodei, S.2    D'Angelo, C.3    Rizzo, A.4    Benassi, B.5    Antonelli, A.6
  • 39
  • 40
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B, Smogorzewska A, de Lange T. TRF2 protects human telomeres from end-to-end fusions. Cell 1998; 92: 401-413
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 41
    • 0037173452 scopus 로고    scopus 로고
    • Micronuclei nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakagefusion- bridge cycles in the cytokinesis-block micronucleus assay
    • Fenech M, Crott JW. Micronuclei nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakagefusion- bridge cycles in the cytokinesis-block micronucleus assay. Mutat Res 2002; 504: 131-136
    • (2002) Mutat Res , vol.504 , pp. 131-136
    • Fenech, M.1    Crott, J.W.2
  • 42
    • 54949099664 scopus 로고    scopus 로고
    • Telomerase activity and telomere length in patients with acute promyelocytic leukemia: Indicative of proliferative activity, disease progression, and overall survival
    • Ghaffari SH, Shayan-Asl N, Jamialahmadi AH, Alimoghaddam K, Ghavamzadeh A. Telomerase activity and telomere length in patients with acute promyelocytic leukemia: indicative of proliferative activity, disease progression, and overall survival. Ann Oncol 2008; 19: 1927-1934
    • (2008) Ann Oncol , vol.19 , pp. 1927-1934
    • Ghaffari, S.H.1    Shayan-Asl, N.2    Jamialahmadi, A.H.3    Alimoghaddam, K.4    Ghavamzadeh, A.5
  • 43
    • 0037108553 scopus 로고    scopus 로고
    • PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors
    • Minucci S, Monestiroli S, Giavara S, Ronzoni S, Marchesi F, Insinga A et al. PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors. Blood 2002; 100: 2989-2995
    • (2002) Blood , vol.100 , pp. 2989-2995
    • Minucci, S.1    Monestiroli, S.2    Giavara, S.3    Ronzoni, S.4    Marchesi, F.5    Insinga, A.6
  • 44
    • 78650203730 scopus 로고    scopus 로고
    • Pilocytic astrocytomas have telomere-associated promyelocytic leukemia bodies without alternatively lengthened telomeres
    • Slatter T, Gifford-Garner J, Wiles A, Tan X, Chen YJ, MacFarlane M et al. Pilocytic astrocytomas have telomere-associated promyelocytic leukemia bodies without alternatively lengthened telomeres. Am J Pathol 2010; 177: 2694-2700
    • (2010) Am J Pathol , vol.177 , pp. 2694-2700
    • Slatter, T.1    Gifford-Garner, J.2    Wiles, A.3    Tan, X.4    Chen, Y.J.5    MacFarlane, M.6
  • 45
    • 27944496124 scopus 로고    scopus 로고
    • Functional human telomeres are recognized as DNA damage in G2 of the cell cycle
    • Verdun RE, Crabbe L, Haggblom C, Karlseder J. Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. Mol Cell 2005; 20: 551-561
    • (2005) Mol Cell , vol.20 , pp. 551-561
    • Verdun, R.E.1    Crabbe, L.2    Haggblom, C.3    Karlseder, J.4
  • 46
    • 77958090630 scopus 로고    scopus 로고
    • Transient activation of the ALT pathway in human primary fibroblasts exposed to high-LET radiation
    • Berardinelli F, Antoccia A, Cherubini R, De Nadal V, Gerardi S, Cirrone GA et al. Transient activation of the ALT pathway in human primary fibroblasts exposed to high-LET radiation. Radiat Res 2010; 174: 539-549
    • (2010) Radiat Res , vol.174 , pp. 539-549
    • Berardinelli, F.1    Antoccia, A.2    Cherubini, R.3    De Nadal, V.4    Gerardi, S.5    Cirrone, G.A.6
  • 48
    • 4644351274 scopus 로고    scopus 로고
    • PML nuclear bodies: Dynamic sensors of DNA damage and cellular stress
    • Dellaire G, Bazett-Jones DP. PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. Bioessays 2004; 9: 963-977
    • (2004) Bioessays , vol.9 , pp. 963-977
    • Dellaire, G.1    Bazett-Jones, D.P.2
  • 50
    • 17144458786 scopus 로고    scopus 로고
    • Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia
    • Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M et al. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia. Nature 1998; 391: 815-818
    • (1998) Nature , vol.391 , pp. 815-818
    • Grignani, F.1    De Matteis, S.2    Nervi, C.3    Tomassoni, L.4    Gelmetti, V.5    Cioce, M.6
  • 51
    • 0032546017 scopus 로고    scopus 로고
    • Role of the histone deacetylase complex in acute promyelocytic leukaemia
    • Lin RJ, Nagy L, Inoue S, Shao W, Miller Jr WH, Evans RM. Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature 1998; 391: 811-814
    • (1998) Nature , vol.391 , pp. 811-814
    • Lin, R.J.1    Nagy, L.2    Inoue, S.3    Shao, W.4    Miller, W.H.5    Evans, R.M.6
  • 52
    • 0031941912 scopus 로고    scopus 로고
    • Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL
    • He LZ, Guidez F, Tribioli C, Peruzzi D, Ruthardt M, Zelent A et al. Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL. Nat Genet 1998; 18: 126-135
    • (1998) Nat Genet , vol.18 , pp. 126-135
    • He, L.Z.1    Guidez, F.2    Tribioli, C.3    Peruzzi, D.4    Ruthardt, M.5    Zelent, A.6
  • 53
    • 0031040058 scopus 로고    scopus 로고
    • Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia
    • Hiorns LR, Swansbury GJ, Mehta J, Min T, Dainton MG, Treleaven J et al. Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia. Br J Haematol 1997; 96: 314-321
    • (1997) Br J Haematol , vol.96 , pp. 314-321
    • Hiorns, L.R.1    Swansbury, G.J.2    Mehta, J.3    Min, T.4    Dainton, M.G.5    Treleaven, J.6
  • 54
    • 0033763906 scopus 로고    scopus 로고
    • Additional chromosome aberrations in acute promyelocytic leukemia: Characteristics and prognostic influence
    • Pantic M, Novak A, Marisavljevic D, Djordjevic V, Elezovic I, Vidovic A et al. Additional chromosome aberrations in acute promyelocytic leukemia: characteristics and prognostic influence. Med Oncol 2000; 17: 307-313
    • (2000) Med Oncol , vol.17 , pp. 307-313
    • Pantic, M.1    Novak, A.2    Marisavljevic, D.3    Djordjevic, V.4    Elezovic, I.5    Vidovic, A.6
  • 56
    • 84892442548 scopus 로고    scopus 로고
    • Transcriptional finetuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors
    • Vian L, Di Carlo M, Pelosi E, Fazi F, Santoro S, Cerio AM et al. Transcriptional finetuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors. Cell Death Differ 2014; 21: 290-301
    • (2014) Cell Death Differ , vol.21 , pp. 290-301
    • Vian, L.1    Di Carlo, M.2    Pelosi, E.3    Fazi, F.4    Santoro, S.5    Cerio, A.M.6
  • 57
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Nati Acad Sci USA 1995; 92: 9363-9367
    • (1995) Proc Nati Acad Sci USA , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3    Acosta, M.4    Scott, G.5    Roskelley, C.6
  • 58
    • 0034693730 scopus 로고    scopus 로고
    • The in vitro micronucleus technique
    • Fenech M. The in vitro micronucleus technique. Mutat Res 2000; 455: 81-95
    • (2000) Mutat Res , vol.455 , pp. 81-95
    • Fenech, M.1
  • 60
    • 17144427653 scopus 로고    scopus 로고
    • Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
    • Racanicchi S, Maccherani C, Liberatore C, Billi M, Gelmetti V, Panigada M et al. Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells. EMBO J 2005; 24: 1232-1242
    • (2005) EMBO J , vol.24 , pp. 1232-1242
    • Racanicchi, S.1    Maccherani, C.2    Liberatore, C.3    Billi, M.4    Gelmetti, V.5    Panigada, M.6
  • 61
    • 0034663431 scopus 로고    scopus 로고
    • PML/RAR alpha fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype
    • Grignani F, Valtieri M, Gabbianelli M, Gelmetti V, Botta R, Luchetti L et al. PML/RAR alpha fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype. Blood 2000; 96: 1531-1537
    • (2000) Blood , vol.96 , pp. 1531-1537
    • Grignani, F.1    Valtieri, M.2    Gabbianelli, M.3    Gelmetti, V.4    Botta, R.5    Luchetti, L.6
  • 62
    • 0031879115 scopus 로고    scopus 로고
    • Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
    • Rufer N, Dragowska W, Thornbury G, Roosnek E, Lansdorp PM. Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat Biotechnol 1998; 16: 743-747
    • (1998) Nat Biotechnol , vol.16 , pp. 743-747
    • Rufer, N.1    Dragowska, W.2    Thornbury, G.3    Roosnek, E.4    Lansdorp, P.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.