Spectroscopic and molecular modeling studies on binding of dorzolamide to bovine and human carbonic anhydrase II

International Journal of Biological Macromolecules

Volumn 80, Issue , 2015, Pages 189-199

  Bijari, Nooshin ^a   Ghobadi, Sirous ^a   Mahdiuni, Hamid ^a   Khodarahmi, Reza ^b   Ghadami, Seyyed Abolghasem ^a  

^a RAZI UNIVERSITY   (Iran)

^b KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Bovine carbonic anhydrase II; Dorzolamide; Human carbonic anhydrase II

Indexed keywords

8 ANILINO 1 NAPHTHALENESULFONIC ACID; CARBONATE DEHYDRATASE II; DORZOLAMIDE; CARBONATE DEHYDRATASE INHIBITOR; PROTEIN BINDING; SULFONAMIDE; THIOPHENE DERIVATIVE;

ARTICLE; BINDING SITE; BOVINE; CATALYSIS; CHEMICAL INTERACTION; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG PROTEIN BINDING; FLUOROMETRY; HUMAN; HUMAN CELL; HYDROGEN BOND; IC50; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN SURFACE HYDROPHOBICITY; PROTEIN TERTIARY STRUCTURE; SPECTROSCOPY; THERMODYNAMICS; ULTRAVIOLET SPECTROSCOPY; VAN DER WAALS INTERACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL PHENOMENA; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; METABOLISM;

BOVINAE;

ANIMALS; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CATALYTIC DOMAIN; CATTLE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; SPECTRUM ANALYSIS; SUBSTRATE SPECIFICITY; SULFONAMIDES; THERMODYNAMICS; THIOPHENES;

EID: 84933512560     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2015.06.028     Document Type: Article

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