메뉴 건너뛰기




Volumn 239, Issue , 2015, Pages 12-18

Ginsenoside Rd attenuates Aβ25-35-induced oxidative stress and apoptosis in primary cultured hippocampal neurons

Author keywords

Amyloid peptide; Apoptosis; Ginsenoside Rd; Hippocampal neurons; Oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; CASPASE 3; CYTOCHROME C; GINSENOSIDE RD; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MESSENGER RNA; NORPHENAZONE; PROBUCOL; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (25-35); BAX PROTEIN, RAT; GINSENOSIDE; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT;

EID: 84933500867     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.06.030     Document Type: Article
Times cited : (53)

References (40)
  • 1
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • M.P. Mattson Pathways towards and away from Alzheimer's disease Nature 430 7000 2004 631 639
    • (2004) Nature , vol.430 , Issue.7000 , pp. 631-639
    • Mattson, M.P.1
  • 2
    • 70350075694 scopus 로고    scopus 로고
    • Neuroscience: Alzheimer's disease
    • L. Mucke Neuroscience: Alzheimer's disease Nature 461 7266 2009 895 897
    • (2009) Nature , vol.461 , Issue.7266 , pp. 895-897
    • Mucke, L.1
  • 3
    • 0025992417 scopus 로고
    • In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity
    • C.J. Pike In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity Brain Res. 563 1-2 1991 311 314
    • (1991) Brain Res. , vol.563 , Issue.1-2 , pp. 311-314
    • Pike, C.J.1
  • 4
    • 0036753272 scopus 로고    scopus 로고
    • Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death
    • D.A. Butterfield Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death Neurobiol. Aging 23 5 2002 655 664
    • (2002) Neurobiol. Aging , vol.23 , Issue.5 , pp. 655-664
    • Butterfield, D.A.1
  • 5
    • 33947195353 scopus 로고    scopus 로고
    • Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease
    • I.N. Shalova Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease Biochim. Biophys. Acta 1770 5 2007 826 832
    • (2007) Biochim. Biophys. Acta , vol.1770 , Issue.5 , pp. 826-832
    • Shalova, I.N.1
  • 6
    • 0036345583 scopus 로고    scopus 로고
    • Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng
    • R.Y. Chan Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng J. Clin. Endocrinol. Metab. 87 8 2002 3691 3695
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , Issue.8 , pp. 3691-3695
    • Chan, R.Y.1
  • 7
    • 53749102440 scopus 로고    scopus 로고
    • Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway
    • X.Z. Lu Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway Acta Pharmacol. Sin. 29 10 2008 1209 1214
    • (2008) Acta Pharmacol. Sin. , vol.29 , Issue.10 , pp. 1209-1214
    • Lu, X.Z.1
  • 8
    • 71049183577 scopus 로고    scopus 로고
    • Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats
    • H. Liu Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats Drug Metab. Dispos. 37 12 2009 2290 2298
    • (2009) Drug Metab. Dispos. , vol.37 , Issue.12 , pp. 2290-2298
    • Liu, H.1
  • 9
    • 84890564306 scopus 로고    scopus 로고
    • Ginsenoside Rd blocks AIF mitochondrio-nuclear translocation and NF-kappaB nuclear accumulation by inhibiting poly(ADP-ribose) polymerase-1 after focal cerebral ischemia in rats
    • G. Hu Ginsenoside Rd blocks AIF mitochondrio-nuclear translocation and NF-kappaB nuclear accumulation by inhibiting poly(ADP-ribose) polymerase-1 after focal cerebral ischemia in rats Neurol. Sci. 34 12 2013 2101 2106
    • (2013) Neurol. Sci. , vol.34 , Issue.12 , pp. 2101-2106
    • Hu, G.1
  • 10
    • 0031983363 scopus 로고    scopus 로고
    • A study of ginsenoside-Rd in a renal ischemia-reperfusion model
    • T. Yokozawa, Z.W. Liu, and E. Dong A study of ginsenoside-Rd in a renal ischemia-reperfusion model Nephron 78 2 1998 201 206
    • (1998) Nephron , vol.78 , Issue.2 , pp. 201-206
    • Yokozawa, T.1    Liu, Z.W.2    Dong, E.3
  • 11
    • 1042304295 scopus 로고    scopus 로고
    • Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice
    • T. Yokozawa, A. Satoh, and E.J. Cho Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice J. Pharm. Pharmacol. 56 1 2004 107 113
    • (2004) J. Pharm. Pharmacol. , vol.56 , Issue.1 , pp. 107-113
    • Yokozawa, T.1    Satoh, A.2    Cho, E.J.3
  • 12
    • 34547840317 scopus 로고    scopus 로고
    • Neuroprotective effect of individual ginsenosides on astrocytes primary culture
    • M.V. Lopez Neuroprotective effect of individual ginsenosides on astrocytes primary culture Biochim. Biophys. Acta 1770 9 2007 1308 1316
    • (2007) Biochim. Biophys. Acta , vol.1770 , Issue.9 , pp. 1308-1316
    • Lopez, M.V.1
  • 13
    • 53549121996 scopus 로고    scopus 로고
    • Protective effects of ginsenoside Rd on PC12 cells against hydrogen peroxide
    • R. Ye Protective effects of ginsenoside Rd on PC12 cells against hydrogen peroxide Biol. Pharm. Bull. 31 10 2008 1923 1927
    • (2008) Biol. Pharm. Bull. , vol.31 , Issue.10 , pp. 1923-1927
    • Ye, R.1
  • 14
    • 65549142297 scopus 로고    scopus 로고
    • Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons
    • R. Ye Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons Neurosci. Res. 64 3 2009 306 310
    • (2009) Neurosci. Res. , vol.64 , Issue.3 , pp. 306-310
    • Ye, R.1
  • 15
    • 84896857538 scopus 로고    scopus 로고
    • Amyloid beta: Multiple mechanisms of toxicity and only some protective effects?
    • P. Carrillo-Mora, R. Luna, and L. Colin-Barenque Amyloid beta: multiple mechanisms of toxicity and only some protective effects? Oxid. Med. Cell. Longev. 2014 2014 795375
    • (2014) Oxid. Med. Cell. Longev. , vol.2014 , pp. 795375
    • Carrillo-Mora, P.1    Luna, R.2    Colin-Barenque, L.3
  • 16
    • 84878712647 scopus 로고    scopus 로고
    • Beta amyloid suppresses the expression of the vitamin d receptor gene and induces the expression of the vitamin d catabolic enzyme gene in hippocampal neurons
    • E. Dursun, D. Gezen-Ak, and S. Yilmazer Beta amyloid suppresses the expression of the vitamin d receptor gene and induces the expression of the vitamin d catabolic enzyme gene in hippocampal neurons Dement. Geriatr. Cogn. Disord. 36 1-2 2013 76 86
    • (2013) Dement. Geriatr. Cogn. Disord. , vol.36 , Issue.1-2 , pp. 76-86
    • Dursun, E.1    Gezen-Ak, D.2    Yilmazer, S.3
  • 17
    • 84900431504 scopus 로고    scopus 로고
    • Geniposide, the component of the Chinese herbal formula Tongluojiunao, protects amyloid-beta peptide (1-42-mediated death of hippocampal neurons via the non-classical estrogen signaling pathway
    • J. Li Geniposide, the component of the Chinese herbal formula Tongluojiunao, protects amyloid-beta peptide (1-42-mediated death of hippocampal neurons via the non-classical estrogen signaling pathway Neural Regen. Res. 9 5 2014 474 480
    • (2014) Neural Regen. Res. , vol.9 , Issue.5 , pp. 474-480
    • Li, J.1
  • 18
    • 84906898861 scopus 로고    scopus 로고
    • Intravenous immunoglobulin treatment preserves and protects primary rat hippocampal neurons and primary human brain cultures against oxidative insults
    • D.K. Lahiri, and B. Ray Intravenous immunoglobulin treatment preserves and protects primary rat hippocampal neurons and primary human brain cultures against oxidative insults Curr. Alzheimer Res. 11 7 2014 645 654
    • (2014) Curr. Alzheimer Res. , vol.11 , Issue.7 , pp. 645-654
    • Lahiri, D.K.1    Ray, B.2
  • 19
    • 84876569513 scopus 로고    scopus 로고
    • Blocking the interaction between apolipoprotein e and Abeta reduces intraneuronal accumulation of Abeta and inhibits synaptic degeneration
    • M.A. Kuszczyk Blocking the interaction between apolipoprotein E and Abeta reduces intraneuronal accumulation of Abeta and inhibits synaptic degeneration Am. J. Pathol. 182 5 2013 1750 1768
    • (2013) Am. J. Pathol. , vol.182 , Issue.5 , pp. 1750-1768
    • Kuszczyk, M.A.1
  • 20
    • 49949111381 scopus 로고    scopus 로고
    • Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells
    • Y.C. Chen Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells PLoS One 3 7 2008 e2637
    • (2008) PLoS One , vol.3 , Issue.7 , pp. e2637
    • Chen, Y.C.1
  • 21
    • 80052640194 scopus 로고    scopus 로고
    • 17beta-Estradiol regulates insulin-degrading enzyme expression via an ERbeta/PI3-K pathway in hippocampus: Relevance to Alzheimer's prevention
    • L. Zhao 17beta-Estradiol regulates insulin-degrading enzyme expression via an ERbeta/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention Neurobiol. Aging 32 11 2011 1949 1963
    • (2011) Neurobiol. Aging , vol.32 , Issue.11 , pp. 1949-1963
    • Zhao, L.1
  • 22
    • 77649189826 scopus 로고    scopus 로고
    • Ophiopogonin D prevents H2O2-induced injury in primary human umbilical vein endothelial cells
    • J. Qian Ophiopogonin D prevents H2O2-induced injury in primary human umbilical vein endothelial cells J. Ethnopharmacol. 128 2 2010 438 445
    • (2010) J. Ethnopharmacol. , vol.128 , Issue.2 , pp. 438-445
    • Qian, J.1
  • 23
    • 77953362499 scopus 로고    scopus 로고
    • Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Abeta(25-35) both in vitro and in vivo
    • C.J. Ruan Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Abeta(25-35) both in vitro and in vivo Neurosci. Res. 67 3 2010 209 214
    • (2010) Neurosci. Res. , vol.67 , Issue.3 , pp. 209-214
    • Ruan, C.J.1
  • 24
    • 74349112938 scopus 로고    scopus 로고
    • Protective effect of selaginellin on glutamate-induced cytotoxicity and apoptosis in differentiated PC12 cells
    • C.J. Wang Protective effect of selaginellin on glutamate-induced cytotoxicity and apoptosis in differentiated PC12 cells Naunyn Schmiedebergs Arch. Pharmacol. 381 1 2010 73 81
    • (2010) Naunyn Schmiedebergs Arch. Pharmacol. , vol.381 , Issue.1 , pp. 73-81
    • Wang, C.J.1
  • 25
    • 68349125562 scopus 로고    scopus 로고
    • Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress
    • X.Z. Wang Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress Theriogenology 72 5 2009 599 611
    • (2009) Theriogenology , vol.72 , Issue.5 , pp. 599-611
    • Wang, X.Z.1
  • 26
    • 84863762839 scopus 로고    scopus 로고
    • Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-beta
    • J.M. Nussbaum Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-beta Nature 485 7400 2012 651 655
    • (2012) Nature , vol.485 , Issue.7400 , pp. 651-655
    • Nussbaum, J.M.1
  • 27
    • 84949116821 scopus 로고    scopus 로고
    • Identification and characterization of Abeta peptide interactors in Alzheimer's disease by structural approaches
    • K.D. Philibert Identification and characterization of Abeta peptide interactors in Alzheimer's disease by structural approaches Front. Aging Neurosci. 6 2014 265
    • (2014) Front. Aging Neurosci. , vol.6 , pp. 265
    • Philibert, K.D.1
  • 28
    • 48149108245 scopus 로고    scopus 로고
    • Protein aggregation in the brain: The molecular basis for Alzheimer's and Parkinson's diseases
    • G.B. Irvine Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases Mol. Med. 14 7-8 2008 451 464
    • (2008) Mol. Med. , vol.14 , Issue.7-8 , pp. 451-464
    • Irvine, G.B.1
  • 29
    • 64149105945 scopus 로고    scopus 로고
    • Efficacy and safety of ginsenoside-Rd for acute ischaemic stroke: A randomized, double-blind, placebo-controlled, phase II multicenter trial
    • X. Liu Efficacy and safety of ginsenoside-Rd for acute ischaemic stroke: a randomized, double-blind, placebo-controlled, phase II multicenter trial Eur. J. Neurol. 16 5 2009 569 575
    • (2009) Eur. J. Neurol. , vol.16 , Issue.5 , pp. 569-575
    • Liu, X.1
  • 30
    • 79951577369 scopus 로고    scopus 로고
    • Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats
    • R. Ye Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats Neurochem. Int. 58 3 2011 391 398
    • (2011) Neurochem. Int. , vol.58 , Issue.3 , pp. 391-398
    • Ye, R.1
  • 31
    • 79952005057 scopus 로고    scopus 로고
    • Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia
    • R. Ye Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia Neuroscience 178 2011 169 180
    • (2011) Neuroscience , vol.178 , pp. 169-180
    • Ye, R.1
  • 32
    • 84904265385 scopus 로고    scopus 로고
    • A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis
    • X. Chai A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis Neural Regen. Res. 9 11 2014 1145 1153
    • (2014) Neural Regen. Res. , vol.9 , Issue.11 , pp. 1145-1153
    • Chai, X.1
  • 33
    • 84916939956 scopus 로고    scopus 로고
    • LIMK1 is involved in the protective effects of bone morphogenetic protein 6 against amyloid-beta-induced neurotoxicity in rat hippocampal neurons
    • L. Sun LIMK1 is involved in the protective effects of bone morphogenetic protein 6 against amyloid-beta-induced neurotoxicity in rat hippocampal neurons J. Alzheimers Dis. 2014
    • (2014) J. Alzheimers Dis.
    • Sun, L.1
  • 34
    • 84873589323 scopus 로고    scopus 로고
    • The effect of genistein on the content and activity of alpha- and beta-secretase and protein kinase C in Abeta-injured hippocampal neurons
    • W. Liao The effect of genistein on the content and activity of alpha- and beta-secretase and protein kinase C in Abeta-injured hippocampal neurons Basic Clin. Pharmacol. Toxicol. 112 3 2013 182 185
    • (2013) Basic Clin. Pharmacol. Toxicol. , vol.112 , Issue.3 , pp. 182-185
    • Liao, W.1
  • 35
    • 0037363893 scopus 로고    scopus 로고
    • Effects of ginsenoside Rd and decursinol on the neurotoxic responses induced by kainic acid in mice
    • J.K. Lee Effects of ginsenoside Rd and decursinol on the neurotoxic responses induced by kainic acid in mice Planta Med. 69 3 2003 230 234
    • (2003) Planta Med. , vol.69 , Issue.3 , pp. 230-234
    • Lee, J.K.1
  • 36
    • 84912051590 scopus 로고    scopus 로고
    • Hesperidin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress in a mouse model of Alzheimer's disease
    • D. Wang Hesperidin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress in a mouse model of Alzheimer's disease Cell. Mol. Neurobiol. 2014
    • (2014) Cell. Mol. Neurobiol.
    • Wang, D.1
  • 37
    • 84922392286 scopus 로고    scopus 로고
    • Ginkgo biloba extract 50 inhibited beta-amyloid-induced oxidative stress in rats' hippocampal neurons: An experimental study
    • C.Y. Xia Ginkgo biloba extract 50 inhibited beta-amyloid-induced oxidative stress in rats' hippocampal neurons: an experimental study Zhongguo Zhong Xi Yi Jie He Za Zhi 34 7 2014 833 838
    • (2014) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.34 , Issue.7 , pp. 833-838
    • Xia, C.Y.1
  • 38
    • 84899672605 scopus 로고    scopus 로고
    • Paris saponin i induces apoptosis via increasing the Bax/Bcl-2 ratio and caspase-3 expression in gefitinib-resistant non-small cell lung cancer in vitro and in vivo
    • H. Jiang Paris saponin I induces apoptosis via increasing the Bax/Bcl-2 ratio and caspase-3 expression in gefitinib-resistant non-small cell lung cancer in vitro and in vivo Mol. Med. Rep. 9 6 2014 2265 2272
    • (2014) Mol. Med. Rep. , vol.9 , Issue.6 , pp. 2265-2272
    • Jiang, H.1
  • 39
    • 84868258164 scopus 로고    scopus 로고
    • Sepia ink oligopeptide induces apoptosis in prostate cancer cell lines via caspase-3 activation and elevation of Bax/Bcl-2 ratio
    • F. Huang Sepia ink oligopeptide induces apoptosis in prostate cancer cell lines via caspase-3 activation and elevation of Bax/Bcl-2 ratio Mar. Drugs 10 10 2012 2153 2165
    • (2012) Mar. Drugs , vol.10 , Issue.10 , pp. 2153-2165
    • Huang, F.1
  • 40
    • 84893757349 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced apoptosis in a murine intestinal endocrine cell line by modulation of Bcl-2, Bax and caspase-3
    • L. Lei Lipopolysaccharide-induced apoptosis in a murine intestinal endocrine cell line by modulation of Bcl-2, Bax and caspase-3 Mol. Med. Rep. 8 6 2013 1649 1654
    • (2013) Mol. Med. Rep. , vol.8 , Issue.6 , pp. 1649-1654
    • Lei, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.