Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Aβ25-35 both in vitro and in vivo

Neuroscience Research

Volumn 67, Issue 3, 2010, Pages 209-214

  Ruan, Can Jun ^a   Zhang, Li ^c   Chen, Di Hua ^b   Li, Zhan ^b   Du, Guan Hua ^c   Sun, Lan ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Alzheimer's disease; Beta amyloid25 35; Neuroprotective; Oxidative; ROS; Stilbene

Indexed keywords

2,4 DIMETHOXYSTIBENE; AMYLOID BETA PROTEIN[25-35]; CHOLINE ACETYLTRANSFERASE; ESTRADIOL; STILBENE DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MAZE TEST; MEMBRANE STABILIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE;

ACETYLCHOLINESTERASE; AMYLOID BETA-PROTEIN; ANIMALS; CELL LINE; CELL SURVIVAL; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; FEMALE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; MAZE LEARNING; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MITOCHONDRIAL MEMBRANES; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PEPTIDE FRAGMENTS; REACTIVE OXYGEN SPECIES; STILBENES; SUPEROXIDE DISMUTASE;

EID: 77953362499     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2010.03.009     Document Type: Article

References (20)

1. Andreyev A.Y., Kushnareva Y.E., Starkov A.A. Mitochondrial metabolism of reactive oxygen species. Biochemistry (Mosc.) 2005, 70(2):200-214.
2. Bastianetto S., Ramassamy C., Doré S., Christen Y., Poirier J., Quirion R. The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid. Eur. J. Neurosci. 2000, 12(6):1882-1890.
3. Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994, 77(6):817-827.
4. Choi S.H., Park C.H., Koo J.W., Seo J.H., Kim H.S., Jeong S.J., Lee S.S., Suh Y.H. Memory impairment and cholinergic dysfunction by centrally administered Aβ and carboxyl-terminal fragment of Alzheimer's APP in mice. FASEB 2001, 15(10):1816-1818.
5. Christen Y. Oxidative stress and Alzheimer disease. Am. J. Clin. Nutr. 2000, 71(2):S621-629.
6. Delobette S., Privat A., Maurice T. In vitro aggregation facilities beta-amyloid peptide-(25-35)-induced amnesia in the rat. Eur. J. Pharmacol. 1997, 319:1-4.
7. Fukui K., Takatsu H., Suzuki S., Abe K., Urano S. Appearance of amyloid-like substances and delayed-type apoptosis in rat hippocampus CA1 region through aging and oxidative stress. J. Alzheimer's Dis. 2005, 8(3):299-309.
8. Heo H.J., Kim D.O., Choi S.J., Shin D.H., Lee C.Y. Potent inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid β protein-induced neurotoxicity. J. Agric. Food Chem. 2004, 52(13):4128-4132.
9. Heynekamp J.J., Weber W.M., Hunsaker L.A., Gonzales A.M., Orlando R.A., Deck L.M., Jagt D.L. Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaB. J. Med. Chem. 2006, 49(24):7182-7189.
10. Kweon S.H., Kim Y., Choi H.M. Grape extracts suppress the formating of preneoplastic foci and activity of fattyacid synthase in rat liver. Exp. Mol. Med. 2003, 35(5):371-378.
11. Laursen S.E., Belknap J.K. Intracerebroventricular injections in mice. Some methodological refinements. J. Pharmacol. Methods 1986, 16(4):355-357.
12. Ledirac N., Antherieu S., Dupuy d'Uby A., Jean-Claude C., Rahmani R. Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: key role of reactive oxygen species. Toxical. Sci. 2005, 86:444-452.
13. Mattson M.P. Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol Rev. 1997, 77:1081-1132.
14. Maurice T., Lockhart B.P., Privat A. Amnesia induced in mice by centrally administered β-amyloid peptides involves cholinergic dysfunction. Brain Res. 1996, 706(2):181-193.
15. Molho D., Coillard J. New methods of preparation of some stilbene derivatives. Bull. Soc. Chim. France 1956, 78-93.
16. Perry E.K., Tomlinson B.E., Blessed G., Bergmann K., Gibson P.H., Perry R.H. Correlation of cholinergic abnormalities with seile plagues and mental test scores in senile demential. Br. Med. J. 1978, 2:1457-1459.
17. Wang C.N., Chi C.W., Lin Y.L., Chen C.F., Shiao Y.J. The neuroprotective effects of phytoestrogens on amyloid β protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons. J. Biol. Chem. 2001, 276(7):5287-5295.
18. Wang T., Qin L., Liu B., Liu Y., Wilson B., Eling T.E., Langenbach R., Taniura S., Hong J.S. Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia. J. Neurochem. 2004, 88:939-947.
19. Wilcock G.K., Esiri M.M., Bowen D.M., Smith C.C. Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities. J. Neurol. Sci. 1982, 57:407-417.
20. Zhang H.Y., Liu Y.H., Wang H.Q., Xu J.H., Hu H.T. Puerarin protects PC12 cells against beta-amyloid-induced cell injury. Cell Biol. Int. 2008, 32(10):1230-1237.