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Volumn 36, Issue 1-2, 2013, Pages 76-86

Beta amyloid suppresses the expression of the vitamin D receptor gene and induces the expression of the vitamin D catabolic enzyme gene in hippocampal neurons

Author keywords

24 Hydroxylase; Alzheimer's disease; Beta amyloid protein; Calcium channels; Hippocampus; Vitamin D; Vitamin D receptor

Indexed keywords

AMYLOID BETA PROTEIN; CALCITRIOL; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL L TYPE A1C; COLECALCIFEROL 24 HYDROXYLASE; LACTATE DEHYDROGENASE; MESSENGER RNA; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

EID: 84878712647     PISSN: 14208008     EISSN: 14219824     Source Type: Journal    
DOI: 10.1159/000350319     Document Type: Article
Times cited : (35)

References (55)
  • 1
    • 84055213663 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis and its role in Alzheimer's disease
    • Mu Y, Gage FH: Adult hippocampal neurogenesis and its role in Alzheimer's disease. Mol Neurodegener 2011; 6: 85-94.
    • (2011) Mol Neurodegener , vol.6 , pp. 85-94
    • Mu, Y.1    Gage, F.H.2
  • 2
    • 0026847039 scopus 로고
    • Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans
    • Squire L: Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol Rev 1992; 99: 195-231.
    • (1992) Psychol Rev , vol.99 , pp. 195-231
    • Squire, L.1
  • 3
    • 0031052381 scopus 로고    scopus 로고
    • Amyloid, the presenilins and Alzheimer's disease
    • Hardy J: Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci 1997; 20: 154-159.
    • (1997) Trends Neurosci , vol.20 , pp. 154-159
    • Hardy, J.1
  • 4
    • 0141552123 scopus 로고    scopus 로고
    • Aging of the brain and dementia of the Alzheimer type
    • Kandel ER SJ, Jessel TM (eds):. New York, McGraw-Hill
    • Price DL: Aging of the brain and dementia of the Alzheimer type; in Kandel ER SJ, Jessel TM (eds): Principles of Neural Science. New York, McGraw-Hill, 2000, pp 1149-1161.
    • (2000) Principles of Neural Science , pp. 1149-1161
    • Price, D.L.1
  • 5
    • 33947493213 scopus 로고    scopus 로고
    • Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store
    • Thibault O, Gant JC, Landfield PW: Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell 2007; 6: 307-317.
    • (2007) Aging Cell , vol.6 , pp. 307-317
    • Thibault, O.1    Gant, J.C.2    Landfield, P.W.3
  • 6
    • 0033393340 scopus 로고    scopus 로고
    • L-type calcium channels in the hippocampus and cerebellum of Alzheimer's disease brain tissue
    • Coon A, Wallace DR, Mactutus CF, Booze RM: L-type calcium channels in the hippocampus and cerebellum of Alzheimer's disease brain tissue. Neurobiol Aging 1999; 20: 597-603.
    • (1999) Neurobiol Aging , vol.20 , pp. 597-603
    • Coon, A.1    Wallace, D.R.2    Mactutus, C.F.3    Booze, R.M.4
  • 7
    • 67349222799 scopus 로고    scopus 로고
    • Combination treatment with progesterone and vitamin D hormone may be more effective than monotherapy for nervous system injury and disease
    • Cekic M, Sayeed I, Stein DG: Combination treatment with progesterone and vitamin D hormone may be more effective than monotherapy for nervous system injury and disease. Front Neuroendocrinol 2009; 30: 158-172.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 158-172
    • Cekic, M.1    Sayeed, I.2    Stein, D.G.3
  • 8
    • 10044272155 scopus 로고    scopus 로고
    • Distribution of the vitamin D receptor and 1 alphahydroxylase in human brain
    • Eyles DW, Smith S, Kinobe R, Hewison M, McGrath JJ: Distribution of the vitamin D receptor and 1 alphahydroxylase in human brain. J Chem Neuroanat 2005; 29: 21-30.
    • (2005) J Chem Neuroanat , vol.29 , pp. 21-30
    • Eyles, D.W.1    Smith, S.2    Kinobe, R.3    Hewison, M.4    McGrath, J.J.5
  • 10
    • 71449103001 scopus 로고    scopus 로고
    • Vitamin D, a neuro-immunomodulator: Implications for neurodegenerative and autoimmune diseases
    • Fernandes de Abreu DA, Eyles D, Féron F: Vitamin D, a neuro-immunomodulator: implications for neurodegenerative and autoimmune diseases. Psychoneuroendocrinology 2009; 34(suppl 1):S265-S277.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. S265-S277
    • Fernandes De Abreu, D.A.1    Eyles, D.2    Féron, F.3
  • 12
    • 77955475502 scopus 로고    scopus 로고
    • Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: Cooperative effects of the glucocorticoid receptor, C/EBP beta, and the vitamin D receptor in 24(OH)ase transcription
    • Dhawan P, Christakos S: Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: cooperative effects of the glucocorticoid receptor, C/EBP beta, and the vitamin D receptor in 24(OH)ase transcription. J Cell Biochem 2010; 110: 1314-1323.
    • (2010) J Cell Biochem , vol.110 , pp. 1314-1323
    • Dhawan, P.1    Christakos, S.2
  • 13
    • 84883192606 scopus 로고    scopus 로고
    • Vitamin D inquiry in hippocampal neurons: Consequences of vitamin D-VDR pathway disruption on calcium channel and the vitamin D requirement
    • E-pub ahead of print
    • Gezen-Ak D, Dursun E, Yilmazer S: Vitamin D inquiry in hippocampal neurons: consequences of vitamin D-VDR pathway disruption on calcium channel and the vitamin D requirement. Neurol Sci 2012, E-pub ahead of print.
    • (2012) Neurol Sci
    • Gezen-Ak, D.1    Dursun, E.2    Yilmazer, S.3
  • 14
    • 0026597610 scopus 로고
    • Reduction of vitamin D hormone receptor mRNA levels in Alzheimer as compared to Huntington hippocampus: Correlation with calbindin-28k mRNA levels
    • Sutherland MK, Somerville MJ, Yoong LK, Bergeron C, Haussler MR, McLachlan DR: Reduction of vitamin D hormone receptor mRNA levels in Alzheimer as compared to Huntington hippocampus: correlation with calbindin-28k mRNA levels. Brain Res Mol Brain Res 1992; 13: 239-250.
    • (1992) Brain Res Mol Brain Res , vol.13 , pp. 239-250
    • Sutherland, M.K.1    Somerville, M.J.2    Yoong, L.K.3    Bergeron, C.4    Haussler, M.R.5    McLachlan, D.R.6
  • 15
    • 0035860474 scopus 로고    scopus 로고
    • Chromosome 12 and late onset Alzheimer's disease
    • Poduslo SE, Yin X: Chromosome 12 and late onset Alzheimer's disease. Neurosci Lett 2001; 310: 188-190.
    • (2001) Neurosci Lett , vol.310 , pp. 188-190
    • Poduslo, S.E.1    Yin, X.2
  • 18
    • 84455191654 scopus 로고    scopus 로고
    • Vitamin D receptor and megalin gene polymorphisms and their associations with longitudinal cognitive change in US adults
    • Beydoun MA, Ding EL, Beydoun HA, Tanaka T, Ferrucci L, Zonderman AB: Vitamin D receptor and megalin gene polymorphisms and their associations with longitudinal cognitive change in US adults. Am J Clin Nutr 2012; 95: 163-178.
    • (2012) Am J Clin Nutr , vol.95 , pp. 163-178
    • Beydoun, M.A.1    Ding, E.L.2    Beydoun, H.A.3    Tanaka, T.4    Ferrucci, L.5    Zonderman, A.B.6
  • 26
    • 54049152001 scopus 로고    scopus 로고
    • Prevalence of vitamin D insufficiency in patients with Parkinson's disease and Alzheimer's disease
    • Evatt ML, DeLong MR, Khazai N, Rosen A, Triche S, Tangpricha V: Prevalence of vitamin D insufficiency in patients with Parkinson's disease and Alzheimer's disease. Arch Neurol 2008; 65: 1348-1352.
    • (2008) Arch Neurol , vol.65 , pp. 1348-1352
    • Evatt, M.L.1    Delong, M.R.2    Khazai, N.3    Rosen, A.4    Triche, S.5    Tangpricha, V.6
  • 27
    • 67650879758 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D concentration and cognitive impairment
    • Llewellyn DJ, Langa KM, Lang IA: Serum 25-hydroxyvitamin D concentration and cognitive impairment. J Geriatr Psychiatry Neurol 2009; 22: 188-195.
    • (2009) J Geriatr Psychiatry Neurol , vol.22 , pp. 188-195
    • Llewellyn, D.J.1    Langa, K.M.2    Lang, I.A.3
  • 29
    • 42049095896 scopus 로고    scopus 로고
    • Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?
    • McCann J, Ames BN: Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction? FASEB J 2008; 22: 982-1001.
    • (2008) FASEB J , vol.22 , pp. 982-1001
    • McCann, J.1    Ames, B.N.2
  • 30
    • 33845598391 scopus 로고    scopus 로고
    • Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults
    • Wilkins CH, Sheline YI, Roe CM, Birge SJ, Morris JC: Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Am J Geriatr Psychiatry 2006; 14: 1032-1040.
    • (2006) Am J Geriatr Psychiatry , vol.14 , pp. 1032-1040
    • Wilkins, C.H.1    Sheline, Y.I.2    Roe, C.M.3    Birge, S.J.4    Morris, J.C.5
  • 31
    • 84855883200 scopus 로고    scopus 로고
    • Serum vitamin D deficiency as a predictor of incident non-Alzheimer dementias: A 7-year longitudinal study
    • Annweiler C, Rolland Y, Schott AM, Blain H, Vellas B, Beauchet O: Serum vitamin D deficiency as a predictor of incident non-Alzheimer dementias: a 7-year longitudinal study. Dement Geriatr Cogn Disord 2012; 32: 273-278.
    • (2012) Dement Geriatr Cogn Disord , vol.32 , pp. 273-278
    • Annweiler, C.1    Rolland, Y.2    Schott, A.M.3    Blain, H.4    Vellas, B.5    Beauchet, O.6
  • 32
    • 84863091991 scopus 로고    scopus 로고
    • Vitamin D deficiency, cognitive impairment and dementia: A systematic review and meta-analysis
    • Etgen T, Sander D, Bickel H, Sander K, Förstl H: Vitamin D deficiency, cognitive impairment and dementia: a systematic review and meta-analysis. Dement Geriatr Cogn Disord 2012; 33: 297-305.
    • (2012) Dement Geriatr Cogn Disord , vol.33 , pp. 297-305
    • Etgen, T.1    Sander, D.2    Bickel, H.3    Sander, K.4    Förstl, H.5
  • 35
    • 79951563916 scopus 로고    scopus 로고
    • A novel perspective for Alzheimer's disease: Vitamin D receptor suppression by amyloid and preventing the amyloid induced alterations by vitamin D in cortical neurons
    • Dursun E, Gezen-Ak D, Yilmazer S: A novel perspective for Alzheimer's disease: vitamin D receptor suppression by amyloid and preventing the amyloid induced alterations by vitamin D in cortical neurons. J Alzheimers Dis 2011; 23: 207-219.
    • (2011) J Alzheimers Dis , vol.23 , pp. 207-219
    • Dursun, E.1    Gezen-Ak, D.2    Yilmazer, S.3
  • 38
    • 84863249788 scopus 로고    scopus 로고
    • Genomic and nongenomic signaling induced by 1,25(OH)2-vitamin D3 promotes the recovery of amyloid phagocytosis by Alzheimer's disease macrophages
    • Mizwicki MT, Menegaz D, Zhang J, Barrientos-Durán A, Tse S, Cashman JR, Griffin PR, Fiala M: Genomic and nongenomic signaling induced by 1,25(OH)2-vitamin D3 promotes the recovery of amyloid phagocytosis by Alzheimer's disease macrophages. J Alzheimers Dis 2011; 29: 51-62.
    • (2011) J Alzheimers Dis , vol.29 , pp. 51-62
    • Mizwicki, M.T.1    Menegaz, D.2    Zhang, J.3    Barrientos-Durán, A.4    Tse, S.5    Cashman, J.R.6    Griffin, P.R.7    Fiala, M.8
  • 39
    • 84867878957 scopus 로고    scopus 로고
    • Neuroprotective and immune effects of active forms of vitamin D3 and docosahexaenoic acid in Alzheimer disease patients
    • Fiala M, Mizwicki MT: Neuroprotective and immune effects of active forms of vitamin D3 and docosahexaenoic acid in Alzheimer disease patients. Functional Foods Health Dis 2011; 12: 545-554.
    • (2011) Functional Foods Health Dis , vol.12 , pp. 545-554
    • Fiala, M.1    Mizwicki, M.T.2
  • 40
    • 79952303913 scopus 로고    scopus 로고
    • The effects of vitamin D receptor silencing on the expression of LVSCC-A1C and LVSCC-A1D and the release of NGF in cortical neurons
    • Gezen-Ak D, Dursun E, Yilmazer S: The effects of vitamin D receptor silencing on the expression of LVSCC-A1C and LVSCC-A1D and the release of NGF in cortical neurons. PLoS One 2011; 6:e17553.
    • (2011) PLoS One , vol.6
    • Gezen-Ak, D.1    Dursun, E.2    Yilmazer, S.3
  • 41
    • 0012795129 scopus 로고    scopus 로고
    • Serum-free media for neural cell cultures
    • Fedoroff S, Richardson A (eds) New York, Humana Press
    • Price P, Brewer GJ: Serum-free media for neural cell cultures; in Fedoroff S, Richardson A (eds): Protocols for Neural Cell Culture. New York, Humana Press, 1998, pp 255-264.
    • (1998) Protocols for Neural Cell Culture , pp. 255-264
    • Price, P.1    Brewer, G.J.2
  • 42
    • 0141960033 scopus 로고    scopus 로고
    • Amyloid induces paired helical filament-like tau filaments in tissue culture
    • Ferrari A, Hoerndli F, Baechi T, Nitsch RM, Götz J: Amyloid induces paired helical filament-like tau filaments in tissue culture. J Biol Chem 2003; 278: 40162-40168.
    • (2003) J Biol Chem , vol.278 , pp. 40162-40168
    • Ferrari, A.1    Hoerndli, F.2    Baechi, T.3    Nitsch, R.M.4    Götz, J.5
  • 43
    • 33847643776 scopus 로고    scopus 로고
    • Quantification of mRNA using real-time RT-PCR
    • Nolan T, Hands BE, Bustin SA: Quantification of mRNA using real-time RT-PCR. Nat Protoc 2006; 1: 1556-1582.
    • (2006) Nat Protoc , vol.1 , pp. 1556-1582
    • Nolan, T.1    Hands, B.E.2    Bustin, S.A.3
  • 44
    • 34249092704 scopus 로고    scopus 로고
    • Calcium and neurodegeneration
    • Mattson MP: Calcium and neurodegeneration. Aging Cell 2007; 6: 337-350.
    • (2007) Aging Cell , vol.6 , pp. 337-350
    • Mattson, M.P.1
  • 45
    • 80053906347 scopus 로고    scopus 로고
    • Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine
    • Anekonda TS, Quinn JF: Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine. Biochim Biophys Acta 2011; 1812: 1584-1590.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 1584-1590
    • Anekonda, T.S.1    Quinn, J.F.2
  • 46
    • 0034319190 scopus 로고    scopus 로고
    • Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: Channel formation and disruption of calcium homeostasis
    • Kawahara M, Kuroda Y: Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis. Brain Res Bull 2000; 53: 389-397.
    • (2000) Brain Res Bull , vol.53 , pp. 389-397
    • Kawahara, M.1    Kuroda, Y.2
  • 49
    • 0042536471 scopus 로고    scopus 로고
    • Neuronal and glial calcium signaling in Alzheimer's disease
    • Mattson MP, Chan SL: Neuronal and glial calcium signaling in Alzheimer's disease. Cell Calcium 2003; 34: 385-397.
    • (2003) Cell Calcium , vol.34 , pp. 385-397
    • Mattson, M.P.1    Chan, S.L.2
  • 50
    • 0032005805 scopus 로고    scopus 로고
    • 4-hydroxynonenal, a lipid peroxidation product, inhibits glutamate transport in astrocytes
    • Blanc EM, Keller JN, Fernandez S, Mattson MP: 4-hydroxynonenal, a lipid peroxidation product, inhibits glutamate transport in astrocytes. Glia 1998; 22: 149-160.
    • (1998) Glia , vol.22 , pp. 149-160
    • Blanc, E.M.1    Keller, J.N.2    Fernandez, S.3    Mattson, M.P.4
  • 51
    • 0028981159 scopus 로고
    • Amyloid beta-peptide impairs ion-motive ATPase activities: Evidence for a role in loss of neuronal Ca 2+ homeostasis and cell death
    • Mark RJ, Hensley K, Butterfield DA, Mattson MP: Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca 2+ homeostasis and cell death. J Neurosci 1995; 15: 6239-6249.
    • (1995) J Neurosci , vol.15 , pp. 6239-6249
    • Mark, R.J.1    Hensley, K.2    Butterfield, D.A.3    Mattson, M.P.4
  • 52
    • 0031020993 scopus 로고    scopus 로고
    • Amyloid beta-peptide impairs glucose uptake in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
    • Mark RJ, Pang Z, Geddes JW, Mattson MP: Amyloid beta-peptide impairs glucose uptake in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J Neurosci 1997; 17: 1046-1054.
    • (1997) J Neurosci , vol.17 , pp. 1046-1054
    • Mark, R.J.1    Pang, Z.2    Geddes, J.W.3    Mattson, M.P.4
  • 53
    • 12844274439 scopus 로고    scopus 로고
    • Pharmacological treatment of neuropsychiatric symptoms of dementia: A review of the evidence
    • Sink K, Holden KF, Yaffe K: Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA 2005; 293: 596-608.
    • (2005) JAMA , vol.293 , pp. 596-608
    • Sink, K.1    Holden, K.F.2    Yaffe, K.3
  • 54
    • 33745027879 scopus 로고    scopus 로고
    • Molecular mechanisms for Alzheimer's disease: Implications for neuroimaging and therapeutics
    • Masters C, Cappai R, Barnham KJ, Villemagne VL: Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics. J Neurochem 2006; 97: 1700-1725.
    • (2006) J Neurochem , vol.97 , pp. 1700-1725
    • Masters, C.1    Cappai, R.2    Barnham, K.J.3    Villemagne, V.L.4


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