-
1
-
-
77953762074
-
Coexistence of cardiac troponin T variants reduces heart efficiency
-
Feng, H.-Z. & Jin, J.-P. Coexistence of cardiac troponin T variants reduces heart efficiency. Am. J. Physiol. Heart Circ. Physiol. 299, H97-H105 (2010).
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.299
, pp. H97-H105
-
-
Feng, H.-Z.1
Jin, J.-P.2
-
2
-
-
33747725854
-
A mutation in the fast skeletal muscle troponin i gene causes myopathy and distal arthrogryposis
-
Kimber, E., Tajsharghi, H., Kroksmark, A.-K., Oldfors, A. & Tulinius, M. A mutation in the fast skeletal muscle troponin I gene causes myopathy and distal arthrogryposis. Neurology 67, 597-601 (2006).
-
(2006)
Neurology
, vol.67
, pp. 597-601
-
-
Kimber, E.1
Tajsharghi, H.2
Kroksmark, A.-K.3
Oldfors, A.4
Tulinius, M.5
-
3
-
-
0028852835
-
A mutation in the α tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathy
-
Laing, N.G. et al. A mutation in the α tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathy. Nat. Genet. 9, 75-79 (1995).
-
(1995)
Nat. Genet.
, vol.9
, pp. 75-79
-
-
Laing, N.G.1
-
4
-
-
48849100715
-
Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations inTNNC1-encoded troponin C
-
Landstrom, A.P. et al. Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations inTNNC1-encoded troponin C. J. Mol. Cell. Cardiol. 45, 281-288 (2008).
-
(2008)
J. Mol. Cell. Cardiol.
, vol.45
, pp. 281-288
-
-
Landstrom, A.P.1
-
5
-
-
8144224216
-
Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy
-
Mogensen, J. et al. Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy. J. Am. Coll. Cardiol. 44, 2033-2040 (2004).
-
(2004)
J. Am. Coll. Cardiol.
, vol.44
, pp. 2033-2040
-
-
Mogensen, J.1
-
6
-
-
0037150221
-
Myosin light chain mutation causes autosomal recessive cardiomyopathy with mid-cavitary hypertrophy and restrictive physiology
-
Olson, T.M., Karst, M.L., Whitby, F.G. & Driscoll, D.J. Myosin light chain mutation causes autosomal recessive cardiomyopathy with mid-cavitary hypertrophy and restrictive physiology. Circulation 105, 2337-2340 (2002).
-
(2002)
Circulation
, vol.105
, pp. 2337-2340
-
-
Olson, T.M.1
Karst, M.L.2
Whitby, F.G.3
Driscoll, D.J.4
-
7
-
-
34548650911
-
Congenital myopathy with nemaline rods and cap structures caused by a mutation in the β-tropomyosin gene (TPM2)
-
Tajsharghi, H., Ohlsson, M., Lindberg, C. & Oldfors, A. Congenital myopathy with nemaline rods and cap structures caused by a mutation in the β-tropomyosin gene (TPM2). Arch. Neurol. 64, 1334-1338 (2007).
-
(2007)
Arch. Neurol.
, vol.64
, pp. 1334-1338
-
-
Tajsharghi, H.1
Ohlsson, M.2
Lindberg, C.3
Oldfors, A.4
-
8
-
-
84863535795
-
Chronic coexistence of two troponin T isoforms in adult transgenic mouse cardiomyocytes decreased contractile kinetics and caused dilatative remodeling
-
Yu, Z.-B., Wei, H. & Jin, J.-P. Chronic coexistence of two troponin T isoforms in adult transgenic mouse cardiomyocytes decreased contractile kinetics and caused dilatative remodeling. Am. J. Physiol. Cell Physiol. 303, C24-C32 (2012).
-
(2012)
Am. J. Physiol. Cell Physiol.
, vol.303
, pp. C24-C32
-
-
Yu, Z.-B.1
Wei, H.2
Jin, J.-P.3
-
9
-
-
84903748882
-
Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy
-
Petchey, L.K. et al. Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy. Proc. Natl. Acad. Sci. USA 111, 9515-9520 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 9515-9520
-
-
Petchey, L.K.1
-
10
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
Mendell, J.T. & Olson, E.N. MicroRNAs in stress signaling and human disease. Cell 148, 1172-1187 (2012).
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
11
-
-
78751660177
-
Pervasive roles of microRNAs in cardiovascular biology
-
Small, E.M. & Olson, E.N. Pervasive roles of microRNAs in cardiovascular biology. Nature 469, 336-342 (2011).
-
(2011)
Nature
, vol.469
, pp. 336-342
-
-
Small, E.M.1
Olson, E.N.2
-
12
-
-
1942435249
-
Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs
-
Bartel, D.P. & Chen, C.-Z. Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5, 396-400 (2004).
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 396-400
-
-
Bartel, D.P.1
Chen, C.-Z.2
-
13
-
-
34247589595
-
Control of stress-dependent cardiac growth and gene expression by a microRNA
-
van Rooij, E. et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316, 575-579 (2007).
-
(2007)
Science
, vol.316
, pp. 575-579
-
-
Van Rooij, E.1
-
14
-
-
41149147013
-
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
-
Chen, J.-F. et al. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc. Natl. Acad. Sci. USA 105, 2111-2116 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2111-2116
-
-
Chen, J.-F.1
-
15
-
-
57749121689
-
MicroRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart
-
Liu, N. et al. microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev. 22, 3242-3254 (2008).
-
(2008)
Genes Dev.
, vol.22
, pp. 3242-3254
-
-
Liu, N.1
-
16
-
-
70349202176
-
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice
-
Callis, T.E. et al. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J. Clin. Invest. 119, 2772-2786 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2772-2786
-
-
Callis, T.E.1
-
17
-
-
71549165765
-
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance
-
van Rooij, E. et al. A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev. Cell 17, 662-673 (2009).
-
(2009)
Dev. Cell
, vol.17
, pp. 662-673
-
-
Van Rooij, E.1
-
18
-
-
84888115595
-
MicroRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart
-
Heidersbach, A. et al. microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. eLife 2, e01323 (2013).
-
(2013)
ELife
, vol.2
, pp. e01323
-
-
Heidersbach, A.1
-
19
-
-
22444437609
-
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
-
Zhao, Y., Samal, E. & Srivastava, D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436, 214-220 (2005).
-
(2005)
Nature
, vol.436
, pp. 214-220
-
-
Zhao, Y.1
Samal, E.2
Srivastava, D.3
-
20
-
-
34147153781
-
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
-
Zhao, Y. et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129, 303-317 (2007).
-
(2007)
Cell
, vol.129
, pp. 303-317
-
-
Zhao, Y.1
-
21
-
-
56649105278
-
MicroRNA-138 modulates cardiac patterning during embryonic development
-
Morton, S.U. et al. microRNA-138 modulates cardiac patterning during embryonic development. Proc. Natl. Acad. Sci. USA 105, 17830-17835 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 17830-17835
-
-
Morton, S.U.1
-
22
-
-
79955800181
-
Elevated miR-499 levels blunt the cardiac stress response
-
Shieh, J.T., Huang, Y., Gilmore, J. & Srivastava, D. Elevated miR-499 levels blunt the cardiac stress response. PLoS ONE 6, e19481 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e19481
-
-
Shieh, J.T.1
Huang, Y.2
Gilmore, J.3
Srivastava, D.4
-
23
-
-
84877583076
-
MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress
-
Huang, Z.P. et al. microRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circ. Res. 112, 1234-1243 (2013).
-
(2013)
Circ. Res.
, vol.112
, pp. 1234-1243
-
-
Huang, Z.P.1
-
24
-
-
84901057904
-
Loss of microRNA-155 protects the heart from pathological cardiac hypertrophy
-
Seok, H.Y. et al. Loss of microRNA-155 protects the heart from pathological cardiac hypertrophy. Circ. Res. 114, 1585-1595 (2014).
-
(2014)
Circ. Res.
, vol.114
, pp. 1585-1595
-
-
Seok, H.Y.1
-
25
-
-
84880040358
-
Mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts
-
Chen, J. et al. mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ. Res. 112, 1557-1566 (2013).
-
(2013)
Circ. Res.
, vol.112
, pp. 1557-1566
-
-
Chen, J.1
-
26
-
-
0027478445
-
Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufen
-
Gatignol, A., Buckler, C. & Jeang, KT. Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufen. Mol. Cell. Biol. 13, 2193-2202 (1993).
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2193-2202
-
-
Gatignol, A.1
Buckler, C.2
Jeang, K.T.3
-
27
-
-
0025876881
-
Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR
-
Gatignol, A., Buckler-White, A., Berkhout, B. & Jeang, K.-T. Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR. Science 251, 1597-1600 (1991).
-
(1991)
Science
, vol.251
, pp. 1597-1600
-
-
Gatignol, A.1
Buckler-White, A.2
Berkhout, B.3
Jeang, K.-T.4
-
28
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada, T.P. et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436, 740-744 (2005).
-
(2005)
Nature
, vol.436
, pp. 740-744
-
-
Chendrimada, T.P.1
-
29
-
-
27144550559
-
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
-
Haase, A.D. et al. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep. 6, 961-967 (2005).
-
(2005)
EMBO Rep.
, vol.6
, pp. 961-967
-
-
Haase, A.D.1
-
30
-
-
84868106469
-
Dicer partner proteins tune the length of mature miRNAs in flies and mammals
-
Fukunaga, R. et al. Dicer partner proteins tune the length of mature miRNAs in flies and mammals. Cell 151, 533-546 (2012).
-
(2012)
Cell
, vol.151
, pp. 533-546
-
-
Fukunaga, R.1
-
31
-
-
84867678226
-
TRBP alters human precursor microRNA processing in vitro
-
Lee, H.Y. & Doudna, J.A. TRBP alters human precursor microRNA processing in vitro. RNA 18, 2012-2019 (2012).
-
(2012)
RNA
, vol.18
, pp. 2012-2019
-
-
Lee, H.Y.1
Doudna, J.A.2
-
32
-
-
84919705851
-
Deletion of human tarbp2 reveals cellular microRNA targets and cell-cycle function of TRBP
-
Kim, Y. et al. Deletion of human tarbp2 reveals cellular microRNA targets and cell-cycle function of TRBP. Cell Rep. 9, 1061-1074 (2014).
-
(2014)
Cell Rep.
, vol.9
, pp. 1061-1074
-
-
Kim, Y.1
-
33
-
-
0030008349
-
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
-
Lakso, M. et al. Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc. Natl. Acad. Sci. USA 93, 5860-5865 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5860-5865
-
-
Lakso, M.1
-
34
-
-
0033052048
-
A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells
-
Zhong, J., Peters, A.H., Lee, K. & Braun, R.E. A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells. Nat. Genet. 22, 171-174 (1999).
-
(1999)
Nat. Genet.
, vol.22
, pp. 171-174
-
-
Zhong, J.1
Peters, A.H.2
Lee, K.3
Braun, R.E.4
-
35
-
-
0141445966
-
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
-
Jiao, K. et al. An essential role of Bmp4 in the atrioventricular septation of the mouse heart. Genes Dev. 17, 2362-2367 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 2362-2367
-
-
Jiao, K.1
-
36
-
-
79954932575
-
Heart failure: Advances through genomics
-
Creemers, E.E., Wilde, A.A. & Pinto, Y.M. Heart failure: advances through genomics. Nat. Rev. Genet. 12, 357-362 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 357-362
-
-
Creemers, E.E.1
Wilde, A.A.2
Pinto, Y.M.3
-
37
-
-
85047676586
-
Growth and hypertrophy of the heart: Towards an understanding of cardiac specific and inducible gene expression
-
van Bilsen, M. & Chien, K.R. Growth and hypertrophy of the heart: towards an understanding of cardiac specific and inducible gene expression. Cardiovasc. Res. 27, 1140-1149 (1993).
-
(1993)
Cardiovasc. Res.
, vol.27
, pp. 1140-1149
-
-
Van Bilsen, M.1
Chien, K.R.2
-
38
-
-
84885676191
-
Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy
-
Jiang, J., Wakimoto, H., Seidman, J.G. & Seidman, C.E. Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy. Science 342, 111-114 (2013).
-
(2013)
Science
, vol.342
, pp. 111-114
-
-
Jiang, J.1
Wakimoto, H.2
Seidman, J.G.3
Seidman, C.E.4
-
39
-
-
84904746093
-
Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model
-
Lin, Z. et al. Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model. Circ. Res. 115, 354-363 (2014).
-
(2014)
Circ. Res.
, vol.115
, pp. 354-363
-
-
Lin, Z.1
-
40
-
-
18644364557
-
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein
-
Shin, C.H. et al. Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell 110, 725-735 (2002).
-
(2002)
Cell
, vol.110
, pp. 725-735
-
-
Shin, C.H.1
-
41
-
-
79955665691
-
Homeodomain only protein x is down-regulated in human heart failure
-
Trivedi, C.M., Cappola, T.P., Margulies, K.B. & Epstein, J.A. Homeodomain only protein x is down-regulated in human heart failure. J. Mol. Cell. Cardiol. 50, 1056-1058 (2011).
-
(2011)
J. Mol. Cell. Cardiol.
, vol.50
, pp. 1056-1058
-
-
Trivedi, C.M.1
Cappola, T.P.2
Margulies, K.B.3
Epstein, J.A.4
-
42
-
-
77956604362
-
Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation
-
Trivedi, C.M. et al. Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev. Cell 19, 450-459 (2010).
-
(2010)
Dev. Cell
, vol.19
, pp. 450-459
-
-
Trivedi, C.M.1
-
43
-
-
18644374460
-
Hop is an unusual homeobox gene that modulates cardiac development
-
Chen, F. et al. Hop is an unusual homeobox gene that modulates cardiac development. Cell 110, 713-723 (2002).
-
(2002)
Cell
, vol.110
, pp. 713-723
-
-
Chen, F.1
-
44
-
-
80053611480
-
Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6
-
An, C.I., Dong, Y. & Hagiwara, N. Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev. Biol. 11, 59 (2011).
-
(2011)
BMC Dev. Biol.
, vol.11
, pp. 59
-
-
An, C.I.1
Dong, Y.2
Hagiwara, N.3
-
45
-
-
79960017815
-
Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6
-
Quiat, D. et al. Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6. Proc. Natl. Acad. Sci. USA 108, 10196-10201 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 10196-10201
-
-
Quiat, D.1
-
46
-
-
78149332037
-
Complexity of the microRNA repertoire revealed by next-generation sequencing
-
Lee, L.W. et al. Complexity of the microRNA repertoire revealed by next-generation sequencing. RNA 16, 2170-2180 (2010).
-
(2010)
RNA
, vol.16
, pp. 2170-2180
-
-
Lee, L.W.1
-
47
-
-
84880303015
-
Regulation of cardiac microRNAs by cardiac microRNAs
-
Matkovich, S.J., Hu, Y. & Dorn, G.W. Regulation of cardiac microRNAs by cardiac microRNAs. Circ. Res. 113, 62-71 (2013).
-
(2013)
Circ. Res.
, vol.113
, pp. 62-71
-
-
Matkovich, S.J.1
Hu, Y.2
Dorn, G.W.3
-
48
-
-
84862128379
-
A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma
-
De Vito, C. et al. A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma. Cancer Cell 21, 807-821 (2012).
-
(2012)
Cancer Cell
, vol.21
, pp. 807-821
-
-
De Vito, C.1
-
49
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang, W., Sherman, B.T. & Lempicki, R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57 (2009).
-
(2009)
Nat. Protoc.
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
50
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
Huang, W., Sherman, B.T. & Lempicki, R.A. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 37, 1-13 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 1-13
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
|