메뉴 건너뛰기




Volumn 65, Issue 13, 2015, Pages 1286-1295

Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy the TNT trial

Author keywords

Atherosclerosis; Biomarker; Coronary heart disease; Inflammatory; Oxidation specific epitope

Indexed keywords

APOLIPOPROTEIN B100; ATORVASTATIN; BIOLOGICAL MARKER; EPITOPE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHOLIPID; TRIACYLGLYCEROL; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PYRROLE DERIVATIVE;

EID: 84933059481     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.01.050     Document Type: Article
Times cited : (59)

References (38)
  • 1
    • 84897018581 scopus 로고    scopus 로고
    • The influence of innate and adaptive immune responses on atherosclerosis
    • Witztum JL, Lichtman AH. The influence of innate and adaptive immune responses on atherosclerosis. Annu Rev Pathol 2014;9:73-102.
    • (2014) Annu Rev Pathol , vol.9 , pp. 73-102
    • Witztum, J.L.1    Lichtman, A.H.2
  • 2
    • 79251580687 scopus 로고    scopus 로고
    • Oxidationspecific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity
    • Miller YI, Choi SH, Wiesner P, et al. Oxidationspecific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res 2011;108: 235-48.
    • (2011) Circ Res , vol.108 , pp. 235-248
    • Miller, Y.I.1    Choi, S.H.2    Wiesner, P.3
  • 3
    • 84869074308 scopus 로고    scopus 로고
    • Differential expression of oxidation-specific epitopes and apolipoprotein(a) in progressing and ruptured human coronary and carotid atherosclerotic lesions
    • van Dijk RA, Kolodgie F, Avandia A, et al. Differential expression of oxidation-specific epitopes and apolipoprotein(a) in progressing and ruptured human coronary and carotid atherosclerotic lesions. J Lipid Res 2012;53: 2773-90.
    • (2012) J Lipid Res , vol.53 , pp. 2773-2790
    • Van Dijk, R.A.1    Kolodgie, F.2    Avandia, A.3
  • 5
    • 80054751966 scopus 로고    scopus 로고
    • Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2
    • Kadl A, Sharma PR, Chen W, et al. Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2. Free Rad Biol Med 2011;51: 1903-9.
    • (2011) Free Rad Biol Med , vol.51 , pp. 1903-1909
    • Kadl, A.1    Sharma, P.R.2    Chen, W.3
  • 6
    • 59049086968 scopus 로고    scopus 로고
    • A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma
    • Bergmark C, Dewan A, Orsoni A, et al. A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma. J Lipid Res 2008;49:2230-9.
    • (2008) J Lipid Res , vol.49 , pp. 2230-2239
    • Bergmark, C.1    Dewan, A.2    Orsoni, A.3
  • 7
    • 84884160203 scopus 로고    scopus 로고
    • Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a)
    • Leibundgut G, Scipione C, Yin H, et al. Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a). J Lipid Res 2013;54:2815-30.
    • (2013) J Lipid Res , vol.54 , pp. 2815-2830
    • Leibundgut, G.1    Scipione, C.2    Yin, H.3
  • 8
    • 80054814637 scopus 로고    scopus 로고
    • Oxidized phospholipids on apolipoprotein B-100 (OxPL/apoB) containing lipoproteins: A biomarker predicting cardiovascular disease and cardiovascular events
    • Taleb A, Witztum JL, Tsimikas S. Oxidized phospholipids on apolipoprotein B-100 (OxPL/apoB) containing lipoproteins: A biomarker predicting cardiovascular disease and cardiovascular events. Biomarkers Med 2011;5:673-94.
    • (2011) Biomarkers Med , vol.5 , pp. 673-694
    • Taleb, A.1    Witztum, J.L.2    Tsimikas, S.3
  • 9
    • 77956495725 scopus 로고    scopus 로고
    • Oxidation- specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events
    • Tsimikas S, Mallat Z, Talmud PJ, et al. Oxidation- specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events. J Am Coll Cardiol 2010;56:946-55.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 946-955
    • Tsimikas, S.1    Mallat, Z.2    Talmud, P.J.3
  • 10
    • 84865120887 scopus 로고    scopus 로고
    • Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: A rationale for increased efforts to understand its pathophysiology and develop targeted therapies
    • Tsimikas S, Hall JH. Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: A rationale for increased efforts to understand its pathophysiology and develop targeted therapies. J Am Coll Cardiol 2012;60:716-21.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 716-721
    • Tsimikas, S.1    Hall, J.H.2
  • 11
    • 84899659288 scopus 로고    scopus 로고
    • Proinflammatory interleukin-1 genotypes potentiate the risk of coronary artery disease and cardiovascular events mediated by oxidized phospholipids and lipoprotein(a)
    • Tsimikas S, Duff GW, Berger PB, et al. Proinflammatory interleukin-1 genotypes potentiate the risk of coronary artery disease and cardiovascular events mediated by oxidized phospholipids and lipoprotein(a). J Am Coll Cardiol 2014;63: 1724-34.
    • (2014) J Am Coll Cardiol , vol.63 , pp. 1724-1734
    • Tsimikas, S.1    Duff, G.W.2    Berger, P.B.3
  • 12
    • 0036510381 scopus 로고    scopus 로고
    • Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids, Importance of Schiff base formation and aldol condensation
    • Friedman P, Horkko S, Steinberg D, Witztum JL, Dennis EA. Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids. Importance of Schiff base formation and aldol condensation. J Biol Chem 2002;277:7010-20.
    • (2002) J Biol Chem , vol.277 , pp. 7010-7020
    • Friedman, P.1    Horkko, S.2    Steinberg, D.3    Witztum, J.L.4    Dennis, E.A.5
  • 13
    • 84893456202 scopus 로고    scopus 로고
    • Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages
    • Choi SH, Yin H, Ravandi A, et al. Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages. PLoS One 2013;8:e83145.
    • (2013) PLoS One , vol.8 , pp. e83145
    • Choi, S.H.1    Yin, H.2    Ravandi, A.3
  • 14
    • 84900530931 scopus 로고    scopus 로고
    • Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans
    • Ravandi A, Leibundgut G, Hung MY, et al. Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans. J Am Coll Cardiol 2014;63: 1961-71.
    • (2014) J Am Coll Cardiol , vol.63 , pp. 1961-1971
    • Ravandi, A.1    Leibundgut, G.2    Hung, M.Y.3
  • 15
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005;352:1425-35.
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • Larosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 16
    • 84919632810 scopus 로고    scopus 로고
    • Prediction of cardiovascular events in statin-treated stable coronary patients of the treating to new targets randomized controlled trial by lipid and non-lipid biomarkers
    • Arsenault BJ, Barter P, DeMicco DA, et al. Prediction of cardiovascular events in statin-treated stable coronary patients of the treating to new targets randomized controlled trial by lipid and non-lipid biomarkers. PLoS One 2014;9: E114519.
    • (2014) PLoS One , vol.9 , pp. e114519
    • Arsenault, B.J.1    Barter, P.2    DeMicco, D.A.3
  • 17
    • 84869090395 scopus 로고    scopus 로고
    • Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events
    • Tsimikas S, Willeit P, Willeit J, et al. Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events. J Am Coll Cardiol 2012;60:2218-29.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 2218-2229
    • Tsimikas, S.1    Willeit, P.2    Willeit, J.3
  • 18
    • 65349142018 scopus 로고    scopus 로고
    • Relationship of oxidizedphospholipids onapolipoprotein B-100 particles to race/ethnicity, apolipoprotein(a) isoform size, and cardiovascular risk factors: Results from the Dallas Heart Study
    • Tsimikas S, Clopton P, Brilakis ES, et al. Relationship of oxidizedphospholipids onapolipoprotein B-100 particles to race/ethnicity, apolipoprotein(a) isoform size, and cardiovascular risk factors: results from the Dallas Heart Study. Circulation 2009;119: 1711-9.
    • (2009) Circulation , vol.119 , pp. 1711-1719
    • Tsimikas, S.1    Clopton, P.2    Brilakis, E.S.3
  • 19
    • 84879410282 scopus 로고    scopus 로고
    • Oxidation- specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosis
    • Leibundgut G, Witztum JL, Tsimikas S. Oxidation- specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosis. Curr Opin Pharmacol 2013;13: 168-79.
    • (2013) Curr Opin Pharmacol , vol.13 , pp. 168-179
    • Leibundgut, G.1    Witztum, J.L.2    Tsimikas, S.3
  • 20
    • 77958532945 scopus 로고    scopus 로고
    • Atherogenic lipids and lipoproteins trigger CD36- TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress
    • Seimon TA, Nadolski MJ, Liao X, et al. Atherogenic lipids and lipoproteins trigger CD36- TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab 2010;12:467-82.
    • (2010) Cell Metab , vol.12 , pp. 467-482
    • Seimon, T.A.1    Nadolski, M.J.2    Liao, X.3
  • 21
    • 84878959653 scopus 로고    scopus 로고
    • MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma
    • Wiesner P, Tafelmeier M, Chittka D, et al. MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma. J Lipid Res 2013;54:1877-83.
    • (2013) J Lipid Res , vol.54 , pp. 1877-1883
    • Wiesner, P.1    Tafelmeier, M.2    Chittka, D.3
  • 22
    • 84863445098 scopus 로고    scopus 로고
    • Increased expression of oxidationspecific epitopes and apoptosis are associated with haptoglobin genotype: Possible implications for plaque progression in human atherosclerosis
    • Purushothaman KR, Purushothaman M, Levy AP, et al. Increased expression of oxidationspecific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis. J Am Coll Cardiol 2012;60:112-9.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 112-119
    • Purushothaman, K.R.1    Purushothaman, M.2    Levy, A.P.3
  • 23
    • 0037419857 scopus 로고    scopus 로고
    • Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes
    • Tsimikas S, Bergmark C, Beyer RW, et al. Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes. J Am Coll Cardiol 2003;41:360-70.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 360-370
    • Tsimikas, S.1    Bergmark, C.2    Beyer, R.W.3
  • 24
    • 4544261604 scopus 로고    scopus 로고
    • Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): Shortterm and long-term immunologic responses to oxidized low-density lipoprotein
    • Tsimikas S, Lau HK, Han KR, et al. Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): shortterm and long-term immunologic responses to oxidized low-density lipoprotein. Circulation 2004; 109:3164-70.
    • (2004) Circulation , vol.109 , pp. 3164-3170
    • Tsimikas, S.1    Lau, H.K.2    Han, K.R.3
  • 25
    • 33847659127 scopus 로고    scopus 로고
    • Increased plasma oxidized phospholipid: Apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: A potential biomarker of early atherosclerosis regression
    • Tsimikas S, Aikawa M, Miller FJ Jr., et al. Increased plasma oxidized phospholipid: Apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: A potential biomarker of early atherosclerosis regression. Arterioscler Thromb Vasc Biol 2007; 27:175-81.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 175-181
    • Tsimikas, S.1    Aikawa, M.2    Miller, F.J.3
  • 26
    • 78149340053 scopus 로고    scopus 로고
    • Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet
    • Faghihnia N, Tsimikas S, Miller ER, Witztum JL, Krauss RM. Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet. J Lipid Res 2010;51: 3324-30.
    • (2010) J Lipid Res , vol.51 , pp. 3324-3330
    • Faghihnia, N.1    Tsimikas, S.2    Miller, E.R.3    Witztum, J.L.4    Krauss, R.M.5
  • 27
    • 1542373714 scopus 로고    scopus 로고
    • Changes in dietary fat intake alter plasma levels of oxidized low-density lipoprotein and lipoprotein( a)
    • Silaste ML, Rantala M, Alfthan G, et al. Changes in dietary fat intake alter plasma levels of oxidized low-density lipoprotein and lipoprotein( a). Arterioscler Thromb Vasc Biol 2004; 24:498-503.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 498-503
    • Silaste, M.L.1    Rantala, M.2    Alfthan, G.3
  • 28
    • 33646190667 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: Effect of pravastatin
    • Rodenburg J, Vissers MN, Wiegman A, et al. Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: Effect of pravastatin. J Am Coll Cardiol 2006;47:1803-10.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1803-1810
    • Rodenburg, J.1    Vissers, M.N.2    Wiegman, A.3
  • 29
    • 4544346640 scopus 로고    scopus 로고
    • Highdose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial
    • Tsimikas S, Witztum JL, Miller ER, et al. Highdose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation 2004;110:1406-12.
    • (2004) Circulation , vol.110 , pp. 1406-1412
    • Tsimikas, S.1    Witztum, J.L.2    Miller, E.R.3
  • 30
    • 43049116177 scopus 로고    scopus 로고
    • The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans
    • Ky B, Burke A, Tsimikas S, et al. The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans. J Am Coll Cardiol 2008;51:1653-62.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1653-1662
    • Ky, B.1    Burke, A.2    Tsimikas, S.3
  • 31
    • 44449169081 scopus 로고    scopus 로고
    • The evolution of thienopyridine therapy clopidogrel duration, diabetes, and drug-eluting stents
    • Choi SH, Prasad A, Tsimikas S. The evolution of thienopyridine therapy clopidogrel duration, diabetes, and drug-eluting stents. J Am Coll Cardiol 2008;51:2228-9.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 2228-2229
    • Choi, S.H.1    Prasad, A.2    Tsimikas, S.3
  • 32
    • 66149131879 scopus 로고    scopus 로고
    • Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering) trial
    • Fraley AE, Schwartz GG, Olsson AG, et al. Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: results from the MIRACL (Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering) trial. J Am Coll Cardiol 2009;53:2186-96.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 2186-2196
    • Fraley, A.E.1    Schwartz, G.G.2    Olsson, A.G.3
  • 33
    • 84871360826 scopus 로고    scopus 로고
    • Effects of pitavastatin and atorvastatin on lipoprotein oxidation biomarkers in patients with dyslipidemia
    • Yoshida H, Shoda T, Yanai H, et al. Effects of pitavastatin and atorvastatin on lipoprotein oxidation biomarkers in patients with dyslipidemia. Atherosclerosis 2013;226:161-4.
    • (2013) Atherosclerosis , vol.226 , pp. 161-164
    • Yoshida, H.1    Shoda, T.2    Yanai, H.3
  • 34
    • 70349295182 scopus 로고    scopus 로고
    • Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: A randomized clinical trial
    • Budoff MJ, Ahmadi N, Gul KM, et al. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: A randomized clinical trial. Prev Med 2009;49:101-7.
    • (2009) Prev Med , vol.49 , pp. 101-107
    • Budoff, M.J.1    Ahmadi, N.2    Gul, K.M.3
  • 35
    • 75349112389 scopus 로고    scopus 로고
    • Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium
    • Ahmadi N, Tsimikas S, Hajsadeghi F, et al. Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium. Am J Cardiol 2010;105:459-66.
    • (2010) Am J Cardiol , vol.105 , pp. 459-466
    • Ahmadi, N.1    Tsimikas, S.2    Hajsadeghi, F.3
  • 36
    • 79953699040 scopus 로고    scopus 로고
    • Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice
    • Merki E, Graham M, Taleb A, et al. Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice. J Am Coll Cardiol 2011;57:1611-21.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 1611-1621
    • Merki, E.1    Graham, M.2    Taleb, A.3
  • 37
    • 84933060965 scopus 로고    scopus 로고
    • Antisense therapy targeting apolipoprotein (a) reduces plasma lipoprotein(a) Levels
    • In press
    • Tsimikas S, Viney NJ, Hughes SG, et al. Antisense therapy targeting apolipoprotein (a) reduces plasma lipoprotein(a) Levels. Lancet 2015;In press.
    • (2015) Lancet
    • Tsimikas, S.1    Viney, N.J.2    Hughes, S.G.3
  • 38
    • 84877987644 scopus 로고    scopus 로고
    • Oxidationspecific biomarkers and risk of peripheral artery disease
    • Bertoia ML, Pai JK, Lee JH, et al. Oxidationspecific biomarkers and risk of peripheral artery disease. J Am Coll Cardiol 2013;61:2169-79.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 2169-2179
    • Bertoia, M.L.1    Pai, J.K.2    Lee, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.