-
1
-
-
27644568878
-
Modulation of atherosclerosis in mice by Toll-like receptor 2
-
DOI 10.1172/JCI25482
-
A.E. Mullick, P.S. Tobias, and L.K. Curtiss Modulation of atherosclerosis in mice by Toll-like receptor 2 J. Clin. Invest. 115 2005 3149 3156 (Pubitemid 41567579)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.11
, pp. 3149-3156
-
-
Mullick, A.E.1
Tobias, P.S.2
Curtiss, L.K.3
-
2
-
-
26444571820
-
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
-
DOI 10.1172/JCI22832
-
J.C. Leemans, G. Stokman, N. Claessen, K.M. Rouschop, G.J. Teske, C.J. Kirschning, S. Akira, P.T. van der, J.J. Weening, and S. Florquin Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney J. Clin. Invest. 115 2005 2894 2903 (Pubitemid 41434417)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2894-2903
-
-
Leemans, J.C.1
Stokman, G.2
Claessen, N.3
Rouschop, K.M.4
Teske, G.J.D.5
Kirschning, C.J.6
Akira, S.7
Van Der Poll, T.8
Weening, J.J.9
Florquin, S.10
-
3
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways
-
DOI 10.1074/jbc.M706762200
-
M.T. Nguyen, S. Favelyukis, A.K. Nguyen, D. Reichart, P.A. Scott, A. Jenn, R. Liu-Bryan, C.K. Glass, J.G. Neels, and J.M. Olefsky A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways J. Biol. Chem. 282 2007 35279 35292 (Pubitemid 350232441)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.48
, pp. 35279-35292
-
-
Nguyen, M.T.A.1
Favelyukis, S.2
Nguyen, A.-K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
4
-
-
77952315676
-
Tlr2 is critical for diet-induced metabolic syndrome in a murine model
-
R.W. Himes, and C.W. Smith Tlr2 is critical for diet-induced metabolic syndrome in a murine model FASEB J. 24 2010 731 739
-
(2010)
FASEB J.
, vol.24
, pp. 731-739
-
-
Himes, R.W.1
Smith, C.W.2
-
5
-
-
10644293824
-
Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory
-
DOI 10.1084/jem.20031763
-
M.K. Chang, C.J. Binder, Y.I. Miller, G. Subbanagounder, G.J. Silverman, J.A. Berliner, and J.L. Witztum Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory J. Exp. Med. 200 2004 1359 1370 (Pubitemid 39657284)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.11
, pp. 1359-1370
-
-
Chang, M.-K.1
Binder, C.J.2
Miller, Y.I.3
Subbanagounder, G.4
Silverman, G.J.5
Berliner, J.A.6
Witztum, J.L.7
-
6
-
-
33947321122
-
Inflammatory profile of oxidized phospholipids
-
DOI 10.1160/TH06-08-0474
-
V.N. Bochkov Inflammatory profile of oxidized phospholipids Thromb. Haemostasis 97 2007 348 354 (Pubitemid 46437795)
-
(2007)
Thrombosis and Haemostasis
, vol.97
, Issue.3
, pp. 348-354
-
-
Bochkov, V.N.1
-
7
-
-
14644388840
-
Oxidized phospholipids trigger atherogenic inflammation in murine arteries
-
DOI 10.1161/01.ATV.0000153106.03644.a0
-
A. Furnkranz, A. Schober, V.N. Bochkov, P. Bashtrykov, G. Kronke, A. Kadl, B.R. Binder, C. Weber, and N. Leitinger Oxidized phospholipids trigger atherogenic inflammation in murine arteries Arterioscler. Thromb. Vasc. Biol. 25 2005 633 638 (Pubitemid 40315690)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.3
, pp. 633-638
-
-
Furnkranz, A.1
Schober, A.2
Bochkov, V.N.3
Bashtrykov, P.4
Kronke, G.5
Kadl, A.6
Binder, B.R.7
Weber, C.8
Leitinger, N.9
-
8
-
-
66049157165
-
Induction of CCR2-dependent macrophage accumulation by oxidized phospholipids in the air-pouch model of inflammation
-
A. Kadl, E. Galkina, and N. Leitinger Induction of CCR2-dependent macrophage accumulation by oxidized phospholipids in the air-pouch model of inflammation Arthritis Rheum. 60 2009 1362 1371
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1362-1371
-
-
Kadl, A.1
Galkina, E.2
Leitinger, N.3
-
9
-
-
0345803942
-
Oxidized Phospholipids Induce Expression of Human Heme Oxygenase-1 Involving Activation of cAMP-responsive Element-binding Protein
-
DOI 10.1074/jbc.M304103200
-
G. Kronke, V.N. Bochkov, J. Huber, F. Gruber, S. Bluml, A. Furnkranz, A. Kadl, B.R. Binder, and N. Leitinger Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein J. Biol. Chem. 278 2003 51006 51014 (Pubitemid 38020334)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.51
, pp. 51006-51014
-
-
Kronke, G.1
Bochkov, V.N.2
Huber, J.3
Gruber, F.4
Bluml, S.5
Furnkranz, A.6
Kadl, A.7
Binder, B.R.8
Leitinger, N.9
-
10
-
-
77957260181
-
Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2
-
A. Kadl, A.K. Meher, P.R. Sharma, M.Y. Lee, A.C. Doran, S.R. Johnstone, M.R. Elliott, F. Gruber, J. Han, W. Chen, T. Kensler, K.S. Ravichandran, B.E. Isakson, B.R. Wamhoff, and N. Leitinger Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2 Circ. Res. 107 2010 737 746
-
(2010)
Circ. Res.
, vol.107
, pp. 737-746
-
-
Kadl, A.1
Meher, A.K.2
Sharma, P.R.3
Lee, M.Y.4
Doran, A.C.5
Johnstone, S.R.6
Elliott, M.R.7
Gruber, F.8
Han, J.9
Chen, W.10
Kensler, T.11
Ravichandran, K.S.12
Isakson, B.E.13
Wamhoff, B.R.14
Leitinger, N.15
-
11
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
-
S. Kim, H. Takahashi, W.W. Lin, P. Descargues, S. Grivennikov, Y. Kim, J.L. Luo, and M. Karin Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis Nature 457 2009 102 106
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.W.3
Descargues, P.4
Grivennikov, S.5
Kim, Y.6
Luo, J.L.7
Karin, M.8
-
12
-
-
0037026527
-
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
-
DOI 10.1038/nature01023
-
V.N. Bochkov, A. Kadl, J. Huber, F. Gruber, B.R. Binder, and N. Leitinger Protective role of phospholipid oxidation products in endotoxin-induced tissue damage Nature 419 2002 77 81 (Pubitemid 34987873)
-
(2002)
Nature
, vol.419
, Issue.6902
, pp. 77-81
-
-
Bochkov, V.N.1
Kadl, A.2
Huber, J.3
Gruber, F.4
Binder, B.R.5
Leitinger, N.6
-
13
-
-
10744226347
-
Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2
-
DOI 10.1161/01.ATV.0000079340.80744.B8
-
K.A. Walton, A.L. Cole, M. Yeh, G. Subbanagounder, S.R. Krutzik, R.L. Modlin, R.M. Lucas, J. Nakai, E.J. Smart, D.K. Vora, and J.A. Berliner Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2 Arterioscler. Thromb. Vasc. Biol. 23 2003 1197 1203 (Pubitemid 36871273)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.7
, pp. 1197-1203
-
-
Walton, K.A.1
Cole, A.L.2
Yeh, M.3
Subbanagounder, G.4
Krutzik, S.R.5
Modlin, R.L.6
Lucas, R.M.7
Nakai, J.8
Smart, E.J.9
Vora, D.K.10
Berliner, J.A.11
-
14
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
M.W. Pfaffl A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res. 29 2001 E45 E
-
(2001)
Nucleic Acids Res.
, vol.29
-
-
Pfaffl, M.W.1
-
15
-
-
0036096132
-
++/NFAT
-
++/NFAT Blood 99 2002 199 206
-
(2002)
Blood
, vol.99
, pp. 199-206
-
-
Bochkov, V.N.1
Mechtcheriakova, D.2
Lucerna, M.3
Huber, J.4
Malli, R.5
Graier, W.F.6
Hofer, E.7
Binder, B.R.8
Leitinger, N.9
-
16
-
-
17944387960
-
Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo
-
DOI 10.1074/jbc.272.21.13597
-
A.D. Watson, N. Leitinger, M. Navab, K.F. Faull, S. Horkko, J.L. Witztum, W. Palinski, D. Schwenke, R.G. Salomon, W. Sha, G. Subbanagounder, A.M. Fogelman, and J.A. Berliner Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo J. Biol. Chem. 272 1997 13597 13607 (Pubitemid 27224791)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.21
, pp. 13597-13607
-
-
Watson, A.D.1
Leitinger, N.2
Navab, M.3
Faull, K.F.4
Horkko, S.5
Witztum, J.L.6
Palinski, W.7
Schwenke, D.8
Salomon, R.G.9
Sha, W.10
Subbanagounder, G.11
Fogelman, A.M.12
Berliner, J.A.13
-
17
-
-
7244239196
-
Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac
-
DOI 10.1161/01.RES.0000147310.18962.06
-
K.G. Birukov, V.N. Bochkov, A.A. Birukova, K. Kawkitinarong, A. Rios, A. Leitner, A.D. Verin, G.M. Bokoch, N. Leitinger, and J.G. Garcia Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac Circ. Res. 95 2004 892 901 (Pubitemid 39435004)
-
(2004)
Circulation Research
, vol.95
, Issue.9
, pp. 892-901
-
-
Birukov, K.G.1
Bochkov, V.N.2
Birukova, A.A.3
Kawkitinarong, K.4
Rios, A.5
Leitner, A.6
Verin, A.D.7
Bokoch, G.M.8
Leitinger, N.9
Garcia, J.G.N.10
-
18
-
-
0033789652
-
Determinants of bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position
-
G. Subbanagounder, N. Leitinger, D.C. Schwenke, J.W. Wong, H. Lee, C. Rizza, A.D. Watson, K.F. Faull, A.M. Fogelman, and J.A. Berliner Determinants of bioactivity of oxidized phospholipids: specific oxidized fatty acyl groups at the sn-2 position Arterioscler. Thromb. Vasc. Biol. 20 2000 2248 2254
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
, pp. 2248-2254
-
-
Subbanagounder, G.1
Leitinger, N.2
Schwenke, D.C.3
Wong, J.W.4
Lee, H.5
Rizza, C.6
Watson, A.D.7
Faull, K.F.8
Fogelman, A.M.9
Berliner, J.A.10
-
19
-
-
77949618571
-
Generation and biological activities of oxidized phospholipids
-
V.N. Bochkov, O.V. Oskolkova, K.G. Birukov, A.L. Levonen, C.J. Binder, and J. Stockl Generation and biological activities of oxidized phospholipids Antioxid. Redox. Signal. 12 8 2010 1009 1059
-
(2010)
Antioxid. Redox. Signal.
, vol.12
, Issue.8
, pp. 1009-1059
-
-
Bochkov, V.N.1
Oskolkova, O.V.2
Birukov, K.G.3
Levonen, A.L.4
Binder, C.J.5
Stockl, J.6
-
20
-
-
0030930697
-
Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL
-
K. Ishikawa, M. Navab, N. Leitinger, A.M. Fogelman, and A.J. Lusis Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL J. Clin. Invest. 100 1997 1209 1216 (Pubitemid 27386307)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.5
, pp. 1209-1216
-
-
Ishikawa, K.1
Navab, M.2
Leitinger, N.3
Fogelman, A.M.4
Lusis, A.J.5
-
21
-
-
33750601160
-
CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex
-
DOI 10.1111/j.1462-5822.2006.00756.x
-
T. Nakata, M. Yasuda, M. Fujita, H. Kataoka, K. Kiura, H. Sano, and K. Shibata CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex Cell. Microbiol. 8 2006 1899 1909 (Pubitemid 44680872)
-
(2006)
Cellular Microbiology
, vol.8
, Issue.12
, pp. 1899-1909
-
-
Nakata, T.1
Yasuda, M.2
Fujita, M.3
Kataoka, H.4
Kiura, K.5
Sano, H.6
Shibata, K.7
-
22
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
-
S. Kim, H. Takahashi, W.W. Lin, P. Descargues, S. Grivennikov, Y. Kim, J.L. Luo, and M. Karin Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis Nature 457 2009 102 106
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.W.3
Descargues, P.4
Grivennikov, S.5
Kim, Y.6
Luo, J.L.7
Karin, M.8
-
23
-
-
61549140074
-
Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids
-
E. von Schlieffen, O.V. Oskolkova, G. Schabbauer, F. Gruber, S. Bluml, M. Genest, A. Kadl, C. Marsik, S. Knapp, J. Chow, N. Leitinger, B.R. Binder, and V.N. Bochkov Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids Arterioscler. Thromb. Vasc. Biol. 29 2009 356 362
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 356-362
-
-
Von Schlieffen, E.1
Oskolkova, O.V.2
Schabbauer, G.3
Gruber, F.4
Bluml, S.5
Genest, M.6
Kadl, A.7
Marsik, C.8
Knapp, S.9
Chow, J.10
Leitinger, N.11
Binder, B.R.12
Bochkov, V.N.13
-
24
-
-
38349107040
-
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo
-
N. Kono, T. Inoue, Y. Yoshida, H. Sato, T. Matsusue, H. Itabe, E. Niki, J. Aoki, and H. Arai Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo J. Biol. Chem. 283 2008 1628 1636
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1628-1636
-
-
Kono, N.1
Inoue, T.2
Yoshida, Y.3
Sato, H.4
Matsusue, T.5
Itabe, H.6
Niki, E.7
Aoki, J.8
Arai, H.9
-
25
-
-
48749091598
-
Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy
-
D. Cruz, A.D. Watson, C.S. Miller, D. Montoya, M.T. Ochoa, P.A. Sieling, M.A. Gutierrez, M. Navab, S.T. Reddy, J.L. Witztum, A.M. Fogelman, T.H. Rea, D. Eisenberg, J. Berliner, and R.L. Modlin Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy J. Clin. Invest. 118 2008 2917 2928
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2917-2928
-
-
Cruz, D.1
Watson, A.D.2
Miller, C.S.3
Montoya, D.4
Ochoa, M.T.5
Sieling, P.A.6
Gutierrez, M.A.7
Navab, M.8
Reddy, S.T.9
Witztum, J.L.10
Fogelman, A.M.11
Rea, T.H.12
Eisenberg, D.13
Berliner, J.14
Modlin, R.L.15
-
26
-
-
41949087380
-
Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury
-
DOI 10.1016/j.cell.2008.02.043, PII S0092867408003401
-
Y. Imai, K. Kuba, G.G. Neely, R. Yaghubian-Malhami, T. Perkmann, L.G. van, M. Ermolaeva, R. Veldhuizen, Y.H. Leung, H. Wang, H. Liu, Y. Sun, M. Pasparakis, M. Kopf, C. Mech, S. Bavari, J.S. Peiris, A.S. Slutsky, S. Akira, M. Hultqvist, R. Holmdahl, J. Nicholls, C. Jiang, C.J. Binder, and J.M. Penninger Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury Cell 133 2008 235 249 (Pubitemid 351512299)
-
(2008)
Cell
, vol.133
, Issue.2
, pp. 235-249
-
-
Imai, Y.1
Kuba, K.2
Neely, G.G.3
Yaghubian-Malhami, R.4
Perkmann, T.5
Van Loo, G.6
Ermolaeva, M.7
Veldhuizen, R.8
Leung, Y.H.C.9
Wang, H.10
Liu, H.11
Sun, Y.12
Pasparakis, M.13
Kopf, M.14
Mech, C.15
Bavari, S.16
Peiris, J.S.M.17
Slutsky, A.S.18
Akira, S.19
Hultqvist, M.20
Holmdahl, R.21
Nicholls, J.22
Jiang, C.23
Binder, C.J.24
Penninger, J.M.25
more..
-
27
-
-
0033789652
-
Determinants of bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position
-
G. Subbanagounder, N. Leitinger, D.C. Schwenke, J.W. Wong, H. Lee, C. Rizza, A.D. Watson, K.F. Faull, A.M. Fogelman, and J.A. Berliner Determinants of bioactivity of oxidized phospholipids: specific oxidized fatty acyl groups at the sn-2 position Arterioscler. Thromb. Vasc. Biol. 20 2000 2248 2254
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
, pp. 2248-2254
-
-
Subbanagounder, G.1
Leitinger, N.2
Schwenke, D.C.3
Wong, J.W.4
Lee, H.5
Rizza, C.6
Watson, A.D.7
Faull, K.F.8
Fogelman, A.M.9
Berliner, J.A.10
-
28
-
-
13044265838
-
Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils
-
DOI 10.1073/pnas.96.21.12010
-
N. Leitinger, T.R. Tyner, L. Oslund, C. Rizza, G. Subbanagounder, H. Lee, P.T. Shih, N. Mackman, G. Tigyi, M.C. Territo, J.A. Berliner, and D.K. Vora Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils Proc. Natl. Acad. Sci. U. S. A. 96 1999 12010 12015 (Pubitemid 29502849)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.21
, pp. 12010-12015
-
-
Leitinger, N.1
Tyner, T.R.2
Oslund, L.3
Rizza, C.4
Subbanagounder, G.5
Lee, H.6
Shih, P.T.7
Mackman, N.8
Tigyi, G.9
Territo, M.C.10
Berliner, J.A.11
Vora, D.K.12
-
29
-
-
0037064120
-
Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36
-
DOI 10.1074/jbc.M203318200
-
E.A. Podrez, E. Poliakov, Z. Shen, R. Zhang, Y. Deng, M. Sun, P.J. Finton, L. Shan, B. Gugiu, P.L. Fox, H.F. Hoff, R.G. Salomon, and S.L. Hazen Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36 J. Biol. Chem. 277 2002 38503 38516 (Pubitemid 35154709)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.41
, pp. 38503-38516
-
-
Podrez, E.A.1
Poliakov, E.2
Shen, Z.3
Zhang, R.4
Deng, Y.5
Sun, M.6
Finton, P.J.7
Shan, L.8
Gugiu, B.9
Fox, P.L.10
Hoff, H.F.11
Salomon, R.G.12
Hazen, S.L.13
-
30
-
-
78049250350
-
Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands
-
X.Z. West, N.L. Malinin, A.A. Merkulova, M. Tischenko, B.A. Kerr, E.C. Borden, E.A. Podrez, R.G. Salomon, and T.V. Byzova Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands Nature 467 2010 972 976
-
(2010)
Nature
, vol.467
, pp. 972-976
-
-
West, X.Z.1
Malinin, N.L.2
Merkulova, A.A.3
Tischenko, M.4
Kerr, B.A.5
Borden, E.C.6
Podrez, E.A.7
Salomon, R.G.8
Byzova, T.V.9
-
31
-
-
67349217383
-
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis
-
M.G. Drage, N.D. Pecora, A.G. Hise, M. Febbraio, R.L. Silverstein, D.T. Golenbock, W.H. Boom, and C.V. Harding TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis Cell. Immunol. 258 2009 29 37
-
(2009)
Cell. Immunol.
, vol.258
, pp. 29-37
-
-
Drage, M.G.1
Pecora, N.D.2
Hise, A.G.3
Febbraio, M.4
Silverstein, R.L.5
Golenbock, D.T.6
Boom, W.H.7
Harding, C.V.8
-
32
-
-
34548608447
-
Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
-
DOI 10.1016/j.cell.2007.09.008, PII S009286740701152X
-
M.S. Jin, S.E. Kim, J.Y. Heo, M.E. Lee, H.M. Kim, S.G. Paik, H. Lee, and J.O. Lee Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide Cell 130 2007 1071 1082 (Pubitemid 47410281)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
Lee, M.E.4
Kim, H.M.5
Paik, S.-G.6
Lee, H.7
Lee, J.-O.8
-
33
-
-
34447627336
-
Lipopolysaccharides from atherosclerosis-associated bacteria antagonize TLR4, induce formation of TLR2/1/CD36 complexes in lipid rafts and trigger TLR2-induced inflammatory responses in human vascular endothelial cells
-
DOI 10.1111/j.1462-5822.2007.00935.x
-
M. Triantafilou, F.G. Gamper, P.M. Lepper, M.A. Mouratis, C. Schumann, E. Harokopakis, R.E. Schifferle, G. Hajishengallis, and K. Triantafilou Lipopolysaccharides from atherosclerosis-associated bacteria antagonize TLR4, induce formation of TLR2/1/CD36 complexes in lipid rafts and trigger TLR2-induced inflammatory responses in human vascular endothelial cells Cell. Microbiol. 9 2007 2030 2039 (Pubitemid 47087093)
-
(2007)
Cellular Microbiology
, vol.9
, Issue.8
, pp. 2030-2039
-
-
Triantafilou, M.1
Gamper, F.G.J.2
Lepper, P.M.3
Mouratis, M.A.4
Schumann, C.5
Harokopakis, E.6
Schifferle, R.E.7
Hajishengallis, G.8
Triantafilou, K.9
-
34
-
-
33750070631
-
Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting
-
DOI 10.1074/jbc.M602794200
-
M. Triantafilou, F.G. Gamper, R.M. Haston, M.A. Mouratis, S. Morath, T. Hartung, and K. Triantafilou Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting J. Biol. Chem. 281 2006 31002 31011 (Pubitemid 44582155)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.41
, pp. 31002-31011
-
-
Triantafilou, M.1
Gamper, F.G.J.2
Haston, R.M.3
Mouratis, M.A.4
Morath, S.5
Hartung, T.6
Triantafilou, K.7
-
35
-
-
77958532945
-
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress
-
T.A. Seimon, M.J. Nadolski, X. Liao, J. Magallon, M. Nguyen, N.T. Feric, M.L. Koschinsky, R. Harkewicz, J.L. Witztum, S. Tsimikas, D. Golenbock, K.J. Moore, and I. Tabas Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress Cell Metab. 12 2010 467 482
-
(2010)
Cell Metab.
, vol.12
, pp. 467-482
-
-
Seimon, T.A.1
Nadolski, M.J.2
Liao, X.3
Magallon, J.4
Nguyen, M.5
Feric, N.T.6
Koschinsky, M.L.7
Harkewicz, R.8
Witztum, J.L.9
Tsimikas, S.10
Golenbock, D.11
Moore, K.J.12
Tabas, I.13
-
36
-
-
54049122271
-
Oxidized phospholipid inhibition of Toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: Roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition
-
C. Erridge, S. Kennedy, C.M. Spickett, and D.J. Webb Oxidized phospholipid inhibition of Toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition J. Biol. Chem. 283 2008 24748 24759
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 24748-24759
-
-
Erridge, C.1
Kennedy, S.2
Spickett, C.M.3
Webb, D.J.4
-
37
-
-
0037449723
-
Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells
-
DOI 10.1074/jbc.M209634200
-
Y.I. Miller, S. Viriyakosol, C.J. Binder, J.R. Feramisco, T.N. Kirkland, and J.L. Witztum Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells J. Biol. Chem. 278 2003 1561 1568 (Pubitemid 36801384)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.3
, pp. 1561-1568
-
-
Miller, Y.I.1
Viriyakosol, S.2
Binder, C.J.3
Feramisco, J.R.4
Kirkland, T.N.5
Witztum, J.L.6
-
39
-
-
34547510802
-
Structural biology of the LPS recognition
-
DOI 10.1016/j.ijmm.2007.04.001, PII S1438422107000689
-
R. Jerala Structural biology of the LPS recognition Int. J. Med. Microbiol. 297 2007 353 363 (Pubitemid 47188054)
-
(2007)
International Journal of Medical Microbiology
, vol.297
, Issue.5
, pp. 353-363
-
-
Jerala, R.1
-
40
-
-
78650659753
-
Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation
-
O.V. Oskolkova, T. Afonyushkin, B. Preinerstorfer, W. Bicker, S.E. von, E. Hainzl, S. Demyanets, G. Schabbauer, W. Lindner, A.D. Tselepis, J. Wojta, B.R. Binder, and V.N. Bochkov Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation J. Immunol. 185 2010 7706 7712
-
(2010)
J. Immunol.
, vol.185
, pp. 7706-7712
-
-
Oskolkova, O.V.1
Afonyushkin, T.2
Preinerstorfer, B.3
Bicker, W.4
Von, S.E.5
Hainzl, E.6
Demyanets, S.7
Schabbauer, G.8
Lindner, W.9
Tselepis, A.D.10
Wojta, J.11
Binder, B.R.12
Bochkov, V.N.13
-
41
-
-
34249297995
-
Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors
-
DOI 10.1161/ATVBAHA.107.142638
-
G. Kronke, A. Kadl, E. Ikonomu, S. Bluml, A. Furnkranz, I.J. Sarembock, V.N. Bochkov, M. Exner, B.R. Binder, and N. Leitinger Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors Arterioscler. Thromb. Vasc. Biol. 27 2007 1276 1282 (Pubitemid 46809415)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.6
, pp. 1276-1282
-
-
Kronke, G.1
Kadl, A.2
Ikonomu, E.3
Bluml, S.4
Furnkranz, A.5
Sarembock, I.J.6
Bochkov, V.N.7
Exner, M.8
Binder, B.R.9
Leitinger, N.10
-
42
-
-
67349208391
-
A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids
-
S. Lee, N.M. Gharavi, H. Honda, I. Chang, B. Kim, N. Jen, R. Li, A. Zimman, and J.A. Berliner A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids Free Radic. Biol. Med. 47 2009 145 151
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 145-151
-
-
Lee, S.1
Gharavi, N.M.2
Honda, H.3
Chang, I.4
Kim, B.5
Jen, N.6
Li, R.7
Zimman, A.8
Berliner, J.A.9
-
43
-
-
64749110692
-
Ox-PAPC activation of PMET system increases expression of heme oxygenase-1 in human aortic endothelial cell
-
S. Lee, R. Li, B. Kim, R. Palvolgyi, T. Ho, Q.Z. Yang, J. Xu, W.L. Szeto, H. Honda, and J.A. Berliner Ox-PAPC activation of PMET system increases expression of heme oxygenase-1 in human aortic endothelial cell J. Lipid Res. 50 2009 265 274
-
(2009)
J. Lipid Res.
, vol.50
, pp. 265-274
-
-
Lee, S.1
Li, R.2
Kim, B.3
Palvolgyi, R.4
Ho, T.5
Yang, Q.Z.6
Xu, J.7
Szeto, W.L.8
Honda, H.9
Berliner, J.A.10
-
44
-
-
0347359124
-
Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins
-
DOI 10.1016/j.mvr.2003.09.004
-
K.G. Birukov, N. Leitinger, V.N. Bochkov, and J.G. Garcia Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins Microvasc. Res. 67 2004 18 28 (Pubitemid 38050220)
-
(2004)
Microvascular Research
, vol.67
, Issue.1
, pp. 18-28
-
-
Birukov, K.G.1
Leitinger, N.2
Bochkov, V.N.3
Garcia, J.G.N.4
-
46
-
-
33846458643
-
Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids
-
DOI 10.1161/01.ATV.0000252842.57585.df, PII 0004360520070200000013
-
A. Zimman, K.P. Mouillesseaux, T. Le, N.M. Gharavi, A. Ryvkin, T.G. Graeber, T.T. Chen, A.D. Watson, and J.A. Berliner Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids Arterioscler. Thromb. Vasc. Biol. 27 2007 332 338 (Pubitemid 46143048)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.2
, pp. 332-338
-
-
Zimman, A.1
Mouillesseaux, K.P.2
Le, T.3
Gharavi, N.M.4
Ryvkin, A.5
Graeber, T.G.6
Chen, T.T.7
Watson, A.D.8
Berliner, J.A.9
-
47
-
-
65449115660
-
Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids
-
P.A. Singleton, S. Chatchavalvanich, P. Fu, J. Xing, A.A. Birukova, J.A. Fortune, A.M. Klibanov, J.G. Garcia, and K.G. Birukov Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids Circ. Res. 104 2009 978 986
-
(2009)
Circ. Res.
, vol.104
, pp. 978-986
-
-
Singleton, P.A.1
Chatchavalvanich, S.2
Fu, P.3
Xing, J.4
Birukova, A.A.5
Fortune, J.A.6
Klibanov, A.M.7
Garcia, J.G.8
Birukov, K.G.9
-
48
-
-
33645323281
-
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC
-
R. Li, K.P. Mouillesseaux, D. Montoya, D. Cruz, N. Gharavi, M. Dun, L. Koroniak, and J.A. Berliner Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC Circ. Res. 98 2006 642 650
-
(2006)
Circ. Res.
, vol.98
, pp. 642-650
-
-
Li, R.1
Mouillesseaux, K.P.2
Montoya, D.3
Cruz, D.4
Gharavi, N.5
Dun, M.6
Koroniak, L.7
Berliner, J.A.8
-
49
-
-
0033588208
-
Evidence that phospholipid oxidation products and/or platelet-activating factor play an important role in early atherogenesis: In vitro and in vivo inhibition by WEB 2086
-
G. Subbanagounder, N. Leitinger, P.T. Shih, K.F. Faull, and J.A. Berliner Evidence that phospholipid oxidation products and/or platelet-activating factor play an important role in early atherogenesis: in vitro and in vivo inhibition by WEB 2086 Circ. Res. 85 1999 311 318 (Pubitemid 29398863)
-
(1999)
Circulation Research
, vol.85
, Issue.4
, pp. 311-318
-
-
Subbanagounder, G.1
Leitinger, N.2
Shih, P.T.3
Faull, K.F.4
Berliner, J.A.5
-
50
-
-
0036556784
-
Activation of vascular cells by PAF-like lipids in oxidized LDL
-
DOI 10.1016/S1537-1891(02)00169-6, PII S1537189102001696
-
G.K. Marathe, G.A. Zimmerman, S.M. Prescott, and T.M. McIntyre Activation of vascular cells by PAF-like lipids in oxidized LDL Vasc. Pharmacol. 38 2002 193 200 (Pubitemid 36398265)
-
(2002)
Vascular Pharmacology
, vol.38
, Issue.4
, pp. 193-200
-
-
Marathe, G.K.1
Zimmerman, G.A.2
Prescott, S.M.3
McIntyre, T.M.4
|