-
1
-
-
66349101372
-
Pathogenesis of choriocarcinoma: Clinical, genetic and stem cell perspectives
-
Cheung AN, Zhang HJ, Xue WC and Siu MK: Pathogenesis of choriocarcinoma: Clinical, genetic and stem cell perspectives. Future Oncol 5: 217-231, 2009.
-
(2009)
Future Oncol
, vol.5
, pp. 217-231
-
-
Cheung, A.N.1
Zhang, H.J.2
Xue, W.C.3
Siu, M.K.4
-
2
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
Semenza GL: HIF-1 and tumor progression: Pathophysiology and therapeutics. Trends Mol Med 8 (Suppl): S62-S67, 2002.
-
(2002)
Trends Mol Med
, vol.8
, pp. S62-S67
-
-
Semenza, G.L.1
-
3
-
-
84874629159
-
Hypoxia-regulated microRNAs in human cancer
-
Shen G, Li X, Jia YF, Piazza GA and Xi Y: Hypoxia-regulated microRNAs in human cancer. Acta Pharmacol Sin 34: 336-341, 2013.
-
(2013)
Acta Pharmacol Sin
, vol.34
, pp. 336-341
-
-
Shen, G.1
Li, X.2
Jia, Y.F.3
Piazza, G.A.4
Xi, Y.5
-
4
-
-
1642387020
-
Hypoxiainducible factor (HIF-1)alpha: Its protein stability and biological functions
-
Lee JW, Bae SH, Jeong JW, Kim SH and Kim KW: Hypoxiainducible factor (HIF-1)alpha: Its protein stability and biological functions. Exp Mol Med 36: 1-12, 2004.
-
(2004)
Exp Mol Med
, vol.36
, pp. 1-12
-
-
Lee, J.W.1
Bae, S.H.2
Jeong, J.W.3
Kim, S.H.4
Kim, K.W.5
-
5
-
-
0242330181
-
Oxygen sensing in the hypoxic response pathway: Regulation of the hypoxia-inducible transcription factor
-
Bruick RK: Oxygen sensing in the hypoxic response pathway: Regulation of the hypoxia-inducible transcription factor. Genes Dev 17: 2614-2623, 2003.
-
(2003)
Genes Dev
, vol.17
, pp. 2614-2623
-
-
Bruick, R.K.1
-
6
-
-
0034901463
-
Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
-
Semenza GL: Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology. Trends Mol Med 7: 345-350, 2001.
-
(2001)
Trends Mol Med
, vol.7
, pp. 345-350
-
-
Semenza, G.L.1
-
7
-
-
79954579633
-
EMT: A new vision of hypoxia promoting cancer progression
-
Jiang J, Tang YL and Liang XH: EMT: A new vision of hypoxia promoting cancer progression. Cancer Biol Ther 11: 714-723, 2011.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 714-723
-
-
Jiang, J.1
Tang, Y.L.2
Liang, X.H.3
-
8
-
-
33745297408
-
New signals from the invasive front
-
Christofori G: New signals from the invasive front. Nature 441: 444-450, 2006.
-
(2006)
Nature
, vol.441
, pp. 444-450
-
-
Christofori, G.1
-
9
-
-
84908154922
-
The EMT universe: Space between cancer cell dissemination and metastasis initiation
-
Ombrato L and Malanchi I: The EMT universe: Space between cancer cell dissemination and metastasis initiation. Crit Rev Oncog 19: 349-361, 2014.
-
(2014)
Crit Rev Oncog
, vol.19
, pp. 349-361
-
-
Ombrato, L.1
Malanchi, I.2
-
10
-
-
33645302628
-
The epithelialmesenchymal transition: New insights in signaling, development, and disease
-
Lee JM, Dedhar S, Kalluri R and Thompson EW: The epithelialmesenchymal transition: New insights in signaling, development, and disease. J Cell Biol 172: 973-981, 2006.
-
(2006)
J Cell Biol
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
11
-
-
84901245983
-
MicroRNA-7 inhibits tumor metastasis and reverses epithelialmesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer
-
Zhou X, Hu Y, Dai L, Wang Y, Zhou J, Wang W, Di W and Qiu L: MicroRNA-7 inhibits tumor metastasis and reverses epithelialmesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer. PLoS One 9: e96718, 2014.
-
(2014)
PLoS One
, vol.9
, pp. e96718
-
-
Zhou, X.1
Hu, Y.2
Dai, L.3
Wang, Y.4
Zhou, J.5
Wang, W.6
Di, W.7
Qiu, L.8
-
12
-
-
77958451128
-
MUC4 mucin-induced epithelial to mesenchymal transition: A novel mechanism for metastasis of human ovarian cancer cells
-
Ponnusamy MP, Lakshmanan I, Jain M, Das S, Chakraborty S, Dey P and Batra SK: MUC4 mucin-induced epithelial to mesenchymal transition: A novel mechanism for metastasis of human ovarian cancer cells. Oncogene 29: 5741-5754, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 5741-5754
-
-
Ponnusamy, M.P.1
Lakshmanan, I.2
Jain, M.3
Das, S.4
Chakraborty, S.5
Dey, P.6
Batra, S.K.7
-
13
-
-
84880260044
-
Tumor necrosis factor (TNF) stimulates the epithelial-mesenchymal transition regulator Snail in cholangiocarcinoma
-
Techasen A, Namwat N, Loilome W, Bungkanjana P, Khuntikeo N, Puapairoj A, Jearanaikoon P, Saya H and Yongvanit P: Tumor necrosis factor (TNF) stimulates the epithelial-mesenchymal transition regulator Snail in cholangiocarcinoma. Med Oncol 29: 3083-3091, 2012.
-
(2012)
Med Oncol
, vol.29
, pp. 3083-3091
-
-
Techasen, A.1
Namwat, N.2
Loilome, W.3
Bungkanjana, P.4
Khuntikeo, N.5
Puapairoj, A.6
Jearanaikoon, P.7
Saya, H.8
Yongvanit, P.9
-
14
-
-
80055060696
-
Human hepatocellular carcinomas with 'Stemness'-related marker expression: Keratin 19 expression and a poor prognosis
-
Kim H, Choi GH, Na DC, Ahn EY, Kim GI, Lee JE, Cho JY, Yoo JE, Choi JS and Park YN: Human hepatocellular carcinomas with 'Stemness'-related marker expression: Keratin 19 expression and a poor prognosis. Hepatology 54: 1707-1717, 2011.
-
(2011)
Hepatology
, vol.54
, pp. 1707-1717
-
-
Kim, H.1
Choi, G.H.2
Na, D.C.3
Ahn, E.Y.4
Kim, G.I.5
Lee, J.E.6
Cho, J.Y.7
Yoo, J.E.8
Choi, J.S.9
Park, Y.N.10
-
15
-
-
23844528776
-
The Snail genes as inducers of cell movement and survival: Implications in development and cancer
-
Barrallo-Gimeno A and Nieto MA: The Snail genes as inducers of cell movement and survival: Implications in development and cancer. Development 132: 3151-3161, 2005.
-
(2005)
Development
, vol.132
, pp. 3151-3161
-
-
Barrallo-Gimeno, A.1
Nieto, M.A.2
-
16
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas S, Rand MD and Lake RJ: Notch signaling: Cell fate control and signal integration in development. Science 284: 770-776, 1999.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
17
-
-
5444247778
-
Notch signaling: The demise of elegant simplicity
-
Kadesch T: Notch signaling: The demise of elegant simplicity. Curr Opin Genet Dev 14: 506-512, 2004.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 506-512
-
-
Kadesch, T.1
-
18
-
-
27644561755
-
Hypoxia requires notch signaling to maintain the undifferentiated cell state
-
Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, Lundkvist J, Ruas JL, Poellinger L, Lendahl U and Bondesson M: Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev Cell 9: 617-628, 2005.
-
(2005)
Dev Cell
, vol.9
, pp. 617-628
-
-
Gustafsson, M.V.1
Zheng, X.2
Pereira, T.3
Gradin, K.4
Jin, S.5
Lundkvist, J.6
Ruas, J.L.7
Poellinger, L.8
Lendahl, U.9
Bondesson, M.10
-
19
-
-
34548599785
-
Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung
-
Chen Y, De Marco MA, Graziani I, Gazdar AF, Strack PR, Miele L and Bocchetta M: Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Res 67: 7954-7959, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 7954-7959
-
-
Chen, Y.1
De Marco, M.A.2
Graziani, I.3
Gazdar, A.F.4
Strack, P.R.5
Miele, L.6
Bocchetta, M.7
-
20
-
-
84881228710
-
Association of Dll4/notch and HIF-1-VEGF signaling in the angiogenesis of missed abortion
-
Fang Y, Yu S, Ma Y, Sun P, Ma D, Ji C and Kong B: Association of Dll4/notch and HIF-1-VEGF signaling in the angiogenesis of missed abortion. PLoS One 8: e70667, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e70667
-
-
Fang, Y.1
Yu, S.2
Ma, Y.3
Sun, P.4
Ma, D.5
Ji, C.6
Kong, B.7
-
21
-
-
36549010842
-
Jagged1-mediated Notch activation induces epithelialto-mesenchymal transition through Slug-induced repression of E-cadherin
-
Leong KG, Niessen K, Kulic I, Raouf A, Eaves C, Pollet I and Karsan A: Jagged1-mediated Notch activation induces epithelialto-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med 204: 2935-2948, 2007.
-
(2007)
J Exp Med
, vol.204
, pp. 2935-2948
-
-
Leong, K.G.1
Niessen, K.2
Kulic, I.3
Raouf, A.4
Eaves, C.5
Pollet, I.6
Karsan, A.7
-
22
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
USA
-
Sahlgren C, Gustafsson MV, Jin S, Poellinger L and Lendahl U: Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci USA 105: 6392-6397, 2008.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
23
-
-
75549083984
-
Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
-
Chen J, Imanaka N, Chen J and Griffin JD: Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion. Br J Cancer 102: 351-360, 2010.
-
(2010)
Br J Cancer
, vol.102
, pp. 351-360
-
-
Chen, J.1
Imanaka, N.2
Chen, J.3
Griffin, J.D.4
-
24
-
-
55849139852
-
Notch1 is an effector of Akt and hypoxia in melanoma development
-
Bedogni B, Warneke JA, Nickoloff BJ, Giaccia AJ and Powell MB: Notch1 is an effector of Akt and hypoxia in melanoma development. J Clin Invest 118: 3660-3670, 2008.
-
(2008)
J Clin Invest
, vol.118
, pp. 3660-3670
-
-
Bedogni, B.1
Warneke, J.A.2
Nickoloff, B.J.3
Giaccia, A.J.4
Powell, M.B.5
-
25
-
-
84964315036
-
Suitable housekeeping genes for normalization of transcript abundance analysis by real-time RT-PCR in cultured bovine granulosa cells during hypoxia and differential cell plating density
-
Baddela VS, Baufeld A, Yenuganti VR, Vanselow J and Singh D: Suitable housekeeping genes for normalization of transcript abundance analysis by real-time RT-PCR in cultured bovine granulosa cells during hypoxia and differential cell plating density. Reprod Biol Endocrinol 12: 118, 2014.
-
(2014)
Reprod Biol Endocrinol
, vol.12
, pp. 118
-
-
Baddela, V.S.1
Baufeld, A.2
Yenuganti, V.R.3
Vanselow, J.4
Singh, D.5
-
26
-
-
84894412911
-
HAF drives the switch of HIF-1 to HIF-2 by activating the NF-B pathway, leading to malignant behavior of T24 bladder cancer cells
-
Guan Z, Ding C, Du Y, Zhang K, Zhu JN, Zhang T, He D, Xu S, Wang X and Fan J: HAF drives the switch of HIF-1 to HIF-2 by activating the NF-B pathway, leading to malignant behavior of T24 bladder cancer cells. Int J Oncol 44: 393-402, 2014.
-
(2014)
Int J Oncol
, vol.44
, pp. 393-402
-
-
Guan, Z.1
Ding, C.2
Du, Y.3
Zhang, K.4
Zhu, J.N.5
Zhang, T.6
He, D.7
Xu, S.8
Wang, X.9
Fan, J.10
-
27
-
-
84885190908
-
Notch-1 contributes to epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance in non-small cell lung cancer in vitro and in vivo
-
Xie M, He CS, Wei SH and Zhang L: Notch-1 contributes to epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance in non-small cell lung cancer in vitro and in vivo. Eur J Cancer 49: 3559-3572, 2013.
-
(2013)
Eur J Cancer
, vol.49
, pp. 3559-3572
-
-
Xie, M.1
He, C.S.2
Wei, S.H.3
Zhang, L.4
-
28
-
-
84877077775
-
Pterostilbene exerts antitumor activity via the Notch1 signaling pathway in human lung adenocarcinoma cells
-
Yang Y, Yan X, Duan W, Yan J, Yi W, Liang Z, Wang N, Li Y, Chen W, Yu S, et al: Pterostilbene exerts antitumor activity via the Notch1 signaling pathway in human lung adenocarcinoma cells. PLoS One 8: e62652, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e62652
-
-
Yang, Y.1
Yan, X.2
Duan, W.3
Yan, J.4
Yi, W.5
Liang, Z.6
Wang, N.7
Li, Y.8
Chen, W.9
Yu, S.10
-
29
-
-
84893629663
-
Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells
-
Zhang S, Yang Y, Liang Z, Duan W, Yang J, Yan J, Wang N, Feng W, Ding M, Nie Y, et al: Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells. PLoS One 8: e83699, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e83699
-
-
Zhang, S.1
Yang, Y.2
Liang, Z.3
Duan, W.4
Yang, J.5
Yan, J.6
Wang, N.7
Feng, W.8
Ding, M.9
Nie, Y.10
-
30
-
-
25144466630
-
Positron emission tomography imaging of small animals in anticancer drug development
-
Aboagye EO: Positron emission tomography imaging of small animals in anticancer drug development. Mol Imaging Biol 7: 53-58, 2005.
-
(2005)
Mol Imaging Biol
, vol.7
, pp. 53-58
-
-
Aboagye, E.O.1
-
31
-
-
84883501150
-
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
-
Semenza GL: HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations. J Clin Invest 123: 3664-3671, 2013.
-
(2013)
J Clin Invest
, vol.123
, pp. 3664-3671
-
-
Semenza, G.L.1
-
32
-
-
84919796463
-
Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1alpha stabilization/nuclear translocation in bone metastasis from breast carcinoma
-
Maroni P, Matteucci E, Drago L, Banfi G, Bendinelli P and Desiderio MA: Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1alpha stabilization/nuclear translocation in bone metastasis from breast carcinoma. Exp Cell Res 30: 287-299, 2015.
-
(2015)
Exp Cell Res
, vol.30
, pp. 287-299
-
-
Maroni, P.1
Matteucci, E.2
Drago, L.3
Banfi, G.4
Bendinelli, P.5
Desiderio, M.A.6
-
33
-
-
79955658283
-
The role of hypoxia inducible factor-1alpha in gynecological cancer
-
Seeber LM, Horrée N, Vooijs MA, Heintz AP, van der Wall E, Verheijen RH and van Diest PJ: The role of hypoxia inducible factor-1alpha in gynecological cancer. Crit Rev Oncol Hematol 78: 173-184, 2011.
-
(2011)
Crit Rev Oncol Hematol
, vol.78
, pp. 173-184
-
-
Seeber, L.M.1
Horrée, N.2
Vooijs, M.A.3
Heintz, A.P.4
Van Der Wall, E.5
Verheijen, R.H.6
Van Diest, P.J.7
-
34
-
-
67349198732
-
Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors: A quantitative analysis of HIF-1
-
Miyazawa M, Yasuda M, Fujita M, Hirasawa T, Kajiwara H, Hirabayashi K, Ogane N, Shimizu M, Asanuma H, Murakami M, et al: Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors: A quantitative analysis of HIF-1. Arch Gynecol Obstet 279: 789-796, 2009.
-
(2009)
Arch Gynecol Obstet
, vol.279
, pp. 789-796
-
-
Miyazawa, M.1
Yasuda, M.2
Fujita, M.3
Hirasawa, T.4
Kajiwara, H.5
Hirabayashi, K.6
Ogane, N.7
Shimizu, M.8
Asanuma, H.9
Murakami, M.10
-
36
-
-
84876796112
-
Hypoxiainducible factor-1 (HIF-1) is upregulated in a HIF-1-dependent manner in 518A2 human melanoma cells under hypoxic conditions
-
Mandl M, Kapeller B, Lieber R and Macfelda K: Hypoxiainducible factor-1 (HIF-1) is upregulated in a HIF-1-dependent manner in 518A2 human melanoma cells under hypoxic conditions. Biochem Biophys Res Commun 434: 166-172, 2013.
-
(2013)
Biochem Biophys Res Commun
, vol.434
, pp. 166-172
-
-
Mandl, M.1
Kapeller, B.2
Lieber, R.3
Macfelda, K.4
-
37
-
-
0032891708
-
Induction and nuclear translocation of hypoxiainducible factor-1 (HIF-1): Heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha
-
Chilov D, Camenisch G, Kvietikova I, Ziegler U, Gassmann M and Wenger RH: Induction and nuclear translocation of hypoxiainducible factor-1 (HIF-1): Heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha. J Cell Sci 112: 1203-1212, 1999.
-
(1999)
J Cell Sci
, vol.112
, pp. 1203-1212
-
-
Chilov, D.1
Camenisch, G.2
Kvietikova, I.3
Ziegler, U.4
Gassmann, M.5
Wenger, R.H.6
-
38
-
-
79960699304
-
EMT: New signals from the invasive front
-
Liang X: EMT: New signals from the invasive front. Oral Oncol 47: 686-687, 2011.
-
(2011)
Oral Oncol
, vol.47
, pp. 686-687
-
-
Liang, X.1
-
39
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng AP, Ferrando AA, Lee W, Morris JP IV, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT and Aster JC: Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306: 269-271, 2004.
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris, J.P.I.V.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
Blacklow, S.C.7
Look, A.T.8
Aster, J.C.9
-
40
-
-
84921973696
-
A new tumor suppressor role for the Notch pathway in bladder cancer
-
Rampias T, Vgenopoulou P, Avgeris M, Polyzos A, Stravodimos K, Valavanis C, Scorilas A and Klinakis A: A new tumor suppressor role for the Notch pathway in bladder cancer. Nat Med 20: 1199-1205, 2014.
-
(2014)
Nat Med
, vol.20
, pp. 1199-1205
-
-
Rampias, T.1
Vgenopoulou, P.2
Avgeris, M.3
Polyzos, A.4
Stravodimos, K.5
Valavanis, C.6
Scorilas, A.7
Klinakis, A.8
-
41
-
-
24944450362
-
The transcriptional repressor Snail promotes mammary tumor recurrence
-
Moody SE, Perez D, Pan TC, Sarkisian CJ, Portocarrero CP, Sterner CJ, Notorfrancesco KL, Cardiff RD and Chodosh LA: The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 8: 197-209, 2005.
-
(2005)
Cancer Cell
, vol.8
, pp. 197-209
-
-
Moody, S.E.1
Perez, D.2
Pan, T.C.3
Sarkisian, C.J.4
Portocarrero, C.P.5
Sterner, C.J.6
Notorfrancesco, K.L.7
Cardiff, R.D.8
Chodosh, L.A.9
-
42
-
-
33751252844
-
Value of whole body 18FDG-PET to identify the active site of gestational trophoblastic neoplasia
-
Dhillon T, Palmieri C, Sebire NJ, Lindsay I, Newlands ES, Schmid P, Savage PM, Frank J and Seckl MJ: Value of whole body 18FDG-PET to identify the active site of gestational trophoblastic neoplasia. J Reprod Med 51: 879-887, 2006.
-
(2006)
J Reprod Med
, vol.51
, pp. 879-887
-
-
Dhillon, T.1
Palmieri, C.2
Sebire, N.J.3
Lindsay, I.4
Newlands, E.S.5
Schmid, P.6
Savage, P.M.7
Frank, J.8
Seckl, M.J.9
-
43
-
-
84920283907
-
Gestational trophoblastic tumours: An update for 2014
-
Froeling FE and Seckl MJ: Gestational trophoblastic tumours: An update for 2014. Curr Oncol Rep 16: 408, 2014.
-
(2014)
Curr Oncol Rep
, vol.16
, pp. 408
-
-
Froeling, F.E.1
Seckl, M.J.2
-
44
-
-
84932646093
-
NEMA NU 4-optimized reconstructions for therapy assessment in cancer research with the Inveon small animal PET/CT system
-
Lasnon C, Dugue AE, Briand M, Blanc-Fournier C, Dutoit S, Louis MH and Aide N: NEMA NU 4-optimized reconstructions for therapy assessment in cancer research with the Inveon small animal PET/CT system. Mol Imaging Biol 17: 403-412, 2015.
-
(2015)
Mol Imaging Biol
, vol.17
, pp. 403-412
-
-
Lasnon, C.1
Dugue, A.E.2
Briand, M.3
Blanc-Fournier, C.4
Dutoit, S.5
Louis, M.H.6
Aide, N.7
|