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Volumn 75, Issue 11, 2015, Pages 2222-2231

Microenvironmental remodeling as a parameter and prognostic factor of heterogeneous leukemogenesis in acute myelogenous leukemia

Author keywords

[No Author keywords available]

Indexed keywords

JAGGED1; STROMAL CELL DERIVED FACTOR 1; CALCIUM BINDING PROTEIN; CXCL12 PROTEIN, HUMAN; MEMBRANE PROTEIN; SERRATE PROTEINS; SIGNAL PEPTIDE;

EID: 84932620908     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-3379     Document Type: Article
Times cited : (128)

References (49)
  • 1
    • 33751267902 scopus 로고    scopus 로고
    • Acute myeloid leukaemia
    • Estey E, Dohner H. Acute myeloid leukaemia. Lancet 2006;368: 1894-907.
    • (2006) Lancet , vol.368 , pp. 1894-1907
    • Estey, E.1    Dohner, H.2
  • 2
    • 3242754448 scopus 로고    scopus 로고
    • Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
    • Hope KJ, Jin L, Dick JE. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol 2004;5: 738-43.
    • (2004) Nat Immunol , vol.5 , pp. 738-743
    • Hope, K.J.1    Jin, L.2    Dick, J.E.3
  • 3
    • 0141483064 scopus 로고    scopus 로고
    • Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
    • Passegue E, Jamieson CH, Ailles LE, Weissman IL. Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci U S A 2003;100 Suppl 1: 11842-9.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11842-11849
    • Passegue, E.1    Jamieson, C.H.2    Ailles, L.E.3    Weissman, I.L.4
  • 4
    • 69849104865 scopus 로고    scopus 로고
    • The leukemic stem cell niche: Current concepts and therapeutic opportunities
    • Lane SW, Scadden DT, Gilliland DG. The leukemic stem cell niche: Current concepts and therapeutic opportunities. Blood 2009;114: 1150-7.
    • (2009) Blood , vol.114 , pp. 1150-1157
    • Lane, S.W.1    Scadden, D.T.2    Gilliland, D.G.3
  • 5
    • 77954832702 scopus 로고    scopus 로고
    • Concise review: Multiple niches for hematopoietic stem cell regulations
    • Oh IH, Kwon KR. Concise review: Multiple niches for hematopoietic stem cell regulations. Stem Cells 2010;28: 1243-9.
    • (2010) Stem Cells , vol.28 , pp. 1243-1249
    • Oh, I.H.1    Kwon, K.R.2
  • 6
    • 60849138787 scopus 로고    scopus 로고
    • Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells
    • Hooper AT, Butler JM, Nolan DJ, Kranz A, Iida K, Kobayashi M, et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell 2009;4: 263-74.
    • (2009) Cell Stem Cell , vol.4 , pp. 263-274
    • Hooper, A.T.1    Butler, J.M.2    Nolan, D.J.3    Kranz, A.4    Iida, K.5    Kobayashi, M.6
  • 7
    • 39749164920 scopus 로고    scopus 로고
    • Haematopoietic stem cell release is regulated by circadian oscillations
    • Mendez-Ferrer S, Lucas D, Battista M, Frenette PS.Haematopoietic stem cell release is regulated by circadian oscillations. Nature 2008;452: 442-7.
    • (2008) Nature , vol.452 , pp. 442-447
    • Mendez-Ferrer, S.1    Lucas, D.2    Battista, M.3    Frenette, P.S.4
  • 9
    • 58749104518 scopus 로고    scopus 로고
    • Endochondral ossification is required for haematopoietic stem-cell niche formation
    • Chan CK, Chen CC, Luppen CA, Kim JB, DeBoer AT, Wei K, et al. Endochondral ossification is required for haematopoietic stem-cell niche formation. Nature 2009;457: 490-4.
    • (2009) Nature , vol.457 , pp. 490-494
    • Chan, C.K.1    Chen, C.C.2    Luppen, C.A.3    Kim, J.B.4    DeBoer, A.T.5    Wei, K.6
  • 10
    • 35348921682 scopus 로고    scopus 로고
    • Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
    • Sacchetti B, Funari A, Michienzi S, Di Cesare S, Piersanti S, Saggio I, et al. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 2007;131: 324-36.
    • (2007) Cell , vol.131 , pp. 324-336
    • Sacchetti, B.1    Funari, A.2    Michienzi, S.3    Di Cesare, S.4    Piersanti, S.5    Saggio, I.6
  • 11
    • 77957266167 scopus 로고    scopus 로고
    • Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function
    • Chitteti BR, Cheng YH, Streicher DA, Rodriguez-Rodriguez S, Carlesso N, Srour EF, et al. Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function. J Cell Biochem 2010;111: 284-94.
    • (2010) J Cell Biochem , vol.111 , pp. 284-294
    • Chitteti, B.R.1    Cheng, Y.H.2    Streicher, D.A.3    Rodriguez-Rodriguez, S.4    Carlesso, N.5    Srour, E.F.6
  • 13
    • 84856147560 scopus 로고    scopus 로고
    • Endothelial and perivascular cells maintain haematopoietic stem cells
    • Ding L, Saunders TL, Enikolopov G, Morrison SJ. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 2012;481: 457-62.
    • (2012) Nature , vol.481 , pp. 457-462
    • Ding, L.1    Saunders, T.L.2    Enikolopov, G.3    Morrison, S.J.4
  • 16
    • 67649595326 scopus 로고    scopus 로고
    • Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche
    • Kim JA, Kang YJ, Park G, Kim M, Park YO, Kim H, et al. Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche. Stem Cells 2009;27: 1318-29.
    • (2009) Stem Cells , vol.27 , pp. 1318-1329
    • Kim, J.A.1    Kang, Y.J.2    Park, G.3    Kim, M.4    Park, Y.O.5    Kim, H.6
  • 17
    • 77957020167 scopus 로고    scopus 로고
    • The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche
    • Omatsu Y, Sugiyama T, Kohara H, Kondoh G, Fujii N, Kohno K, et al. The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. Immunity 2010;33: 387-99.
    • (2010) Immunity , vol.33 , pp. 387-399
    • Omatsu, Y.1    Sugiyama, T.2    Kohara, H.3    Kondoh, G.4    Fujii, N.5    Kohno, K.6
  • 18
    • 33845445939 scopus 로고    scopus 로고
    • Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
    • Sugiyama T, Kohara H, Noda M, Nagasawa T. Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 2006;25: 977-88.
    • (2006) Immunity , vol.25 , pp. 977-988
    • Sugiyama, T.1    Kohara, H.2    Noda, M.3    Nagasawa, T.4
  • 19
    • 36148993920 scopus 로고    scopus 로고
    • Angiopoietin-1 supports induction of hematopoietic activity in human CD34-bone marrow cells
    • Nakamura Y, Yahata T, Muguruma Y, Uno T, Sato T, Matsuzawa H, et al. Angiopoietin-1 supports induction of hematopoietic activity in human CD34-bone marrow cells. Exp Hematol 2007;35: 1872-83.
    • (2007) Exp Hematol , vol.35 , pp. 1872-1883
    • Nakamura, Y.1    Yahata, T.2    Muguruma, Y.3    Uno, T.4    Sato, T.5    Matsuzawa, H.6
  • 20
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003;425: 836-41.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3    Huang, H.4    He, X.5    Tong, W.G.6
  • 21
    • 21244472780 scopus 로고    scopus 로고
    • Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
    • Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Grunewald E, et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med 2005;201: 1781-91.
    • (2005) J Exp Med , vol.201 , pp. 1781-1791
    • Stier, S.1    Ko, Y.2    Forkert, R.3    Lutz, C.4    Neuhaus, T.5    Grunewald, E.6
  • 22
    • 21344474104 scopus 로고    scopus 로고
    • Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
    • Nilsson SK, Johnston HM, Whitty GA, Williams B, Webb RJ, Denhardt DT, et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 2005; 106: 1232-9.
    • (2005) Blood , vol.106 , pp. 1232-1239
    • Nilsson, S.K.1    Johnston, H.M.2    Whitty, G.A.3    Williams, B.4    Webb, R.J.5    Denhardt, D.T.6
  • 23
    • 34547874440 scopus 로고    scopus 로고
    • Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche
    • Arai F, Suda T. Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann N Y Acad Sci 2007;1106: 41-53.
    • (2007) Ann N Y Acad Sci , vol.1106 , pp. 41-53
    • Arai, F.1    Suda, T.2
  • 24
    • 50949111817 scopus 로고    scopus 로고
    • Osteolineage niche cells initiate hematopoietic stem cell mobilization
    • Mayack SR, Wagers AJ.Osteolineage niche cells initiate hematopoietic stem cell mobilization. Blood 2008;112: 519-31.
    • (2008) Blood , vol.112 , pp. 519-531
    • Mayack, S.R.1    Wagers, A.J.2
  • 25
    • 35948984135 scopus 로고    scopus 로고
    • Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
    • Ishikawa F, Yoshida S, Saito Y, Hijikata A, Kitamura H, Tanaka S, et al. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region. Nat Biotechnol 2007;25: 1315-21.
    • (2007) Nat Biotechnol , vol.25 , pp. 1315-1321
    • Ishikawa, F.1    Yoshida, S.2    Saito, Y.3    Hijikata, A.4    Kitamura, H.5    Tanaka, S.6
  • 26
    • 57849108116 scopus 로고    scopus 로고
    • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
    • Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science 2008;322: 1861-5.
    • (2008) Science , vol.322 , pp. 1861-1865
    • Colmone, A.1    Amorim, M.2    Pontier, A.L.3    Wang, S.4    Jablonski, E.5    Sipkins, D.A.6
  • 27
    • 84859832491 scopus 로고    scopus 로고
    • Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia
    • Zhang B, Ho YW, Huang Q, Maeda T, Lin A, Lee SU, et al. Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia. Cancer Cell 2012;21: 577-92.
    • (2012) Cancer Cell , vol.21 , pp. 577-592
    • Zhang, B.1    Ho, Y.W.2    Huang, Q.3    Maeda, T.4    Lin, A.5    Lee, S.U.6
  • 28
    • 84855858755 scopus 로고    scopus 로고
    • Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia
    • Frisch BJ, Ashton JM, Xing L, Becker MW, Jordan CT, Calvi LM. Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia. Blood 2012;119: 540-50.
    • (2012) Blood , vol.119 , pp. 540-550
    • Frisch, B.J.1    Ashton, J.M.2    Xing, L.3    Becker, M.W.4    Jordan, C.T.5    Calvi, L.M.6
  • 29
    • 84884164883 scopus 로고    scopus 로고
    • Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche
    • Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell 2013;13: 285-99.
    • (2013) Cell Stem Cell , vol.13 , pp. 285-299
    • Schepers, K.1    Pietras, E.M.2    Reynaud, D.3    Flach, J.4    Binnewies, M.5    Garg, T.6
  • 30
    • 77954088647 scopus 로고    scopus 로고
    • Stem cell regulatory niches and their role in normal and malignant hematopoiesis
    • Carlesso N, Cardoso AA. Stem cell regulatory niches and their role in normal and malignant hematopoiesis. Curr Opin Hematol 2010;17: 281-6.
    • (2010) Curr Opin Hematol , vol.17 , pp. 281-286
    • Carlesso, N.1    Cardoso, A.A.2
  • 31
    • 84896735528 scopus 로고    scopus 로고
    • Advances in understanding the leukaemia microenvironment
    • Tabe Y, Konopleva M. Advances in understanding the leukaemia microenvironment. Br J Haematol 2014;164: 767-78.
    • (2014) Br J Haematol , vol.164 , pp. 767-778
    • Tabe, Y.1    Konopleva, M.2
  • 32
    • 67649274467 scopus 로고    scopus 로고
    • Mesenchymal stromal cells expanded in human allogenic cord blood serum display higher selfrenewal and enhanced osteogenic potential
    • Jung J, Moon N, Ahn JY, OhEJ, Kim M, Cho CS, et al. Mesenchymal stromal cells expanded in human allogenic cord blood serum display higher selfrenewal and enhanced osteogenic potential. Stem Cells Dev 2009;18: 559-71.
    • (2009) Stem Cells Dev , vol.18 , pp. 559-571
    • Jung, J.1    Moon, N.2    Ahn, J.Y.3    Oh, E.J.4    Kim, M.5    Cho, C.S.6
  • 33
    • 77149139509 scopus 로고    scopus 로고
    • Disruption of bis leads to the deterioration of the vascular niche for hematopoietic stem cells
    • Kwon KR, Ahn JY, KimMS, Jung JY, Lee JH, OhIH. Disruption of bis leads to the deterioration of the vascular niche for hematopoietic stem cells. Stem Cells 2010;28: 268-78.
    • (2010) Stem Cells , vol.28 , pp. 268-278
    • Kwon, K.R.1    Ahn, J.Y.2    Kim, M.S.3    Jung, J.Y.4    Lee, J.H.5    Oh, I.H.6
  • 34
    • 0034672161 scopus 로고    scopus 로고
    • +)CD38(-)) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts
    • +)CD38(-)) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts. Blood 2000;96: 4160-8.
    • (2000) Blood , vol.96 , pp. 4160-4168
    • Oh, I.H.1    Lau, A.2    Eaves, C.J.3
  • 35
    • 77449121923 scopus 로고    scopus 로고
    • Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells
    • Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, et al. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell 2010;6: 251-64.
    • (2010) Cell Stem Cell , vol.6 , pp. 251-264
    • Butler, J.M.1    Nolan, D.J.2    Vertes, E.L.3    Varnum-Finney, B.4    Kobayashi, H.5    Hooper, A.T.6
  • 36
    • 73949136873 scopus 로고    scopus 로고
    • Undifferentiated hematopoietic cells are characterized by a genome-wide undermethylation dip around the transcription start site and a hierarchical epigenetic plasticity
    • Chung YS, Kim HJ, Kim TM, Hong SH, Kwon KR, An S, et al. Undifferentiated hematopoietic cells are characterized by a genome-wide undermethylation dip around the transcription start site and a hierarchical epigenetic plasticity. Blood 2009;114: 4968-78.
    • (2009) Blood , vol.114 , pp. 4968-4978
    • Chung, Y.S.1    Kim, H.J.2    Kim, T.M.3    Hong, S.H.4    Kwon, K.R.5    An, S.6
  • 37
    • 84899013039 scopus 로고    scopus 로고
    • Molecular integration of HoxB4 and STAT3 for self-renewal of hematopoietic stem cells: A model of molecular convergence for stemness
    • Hong SH, Yang SJ, Kim TM, Shim JS, Lee HS, Lee GY, et al. Molecular integration of HoxB4 and STAT3 for self-renewal of hematopoietic stem cells: A model of molecular convergence for stemness. Stem Cells 2014; 32: 1313-22.
    • (2014) Stem Cells , vol.32 , pp. 1313-1322
    • Hong, S.H.1    Yang, S.J.2    Kim, T.M.3    Shim, J.S.4    Lee, H.S.5    Lee, G.Y.6
  • 39
    • 77950991204 scopus 로고    scopus 로고
    • In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential ofmesenchymal stem cells reveals a complex hierarchy of lineage commitment
    • Russell KC, Phinney DG, Lacey MR, Barrilleaux BL, Meyertholen KE, O'Connor KC. In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential ofmesenchymal stem cells reveals a complex hierarchy of lineage commitment. Stem Cells 2010;28: 788-98.
    • (2010) Stem Cells , vol.28 , pp. 788-798
    • Russell, K.C.1    Phinney, D.G.2    Lacey, M.R.3    Barrilleaux, B.L.4    Meyertholen, K.E.5    O'Connor, K.C.6
  • 40
    • 77956574958 scopus 로고    scopus 로고
    • Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells
    • Nakamura Y, Arai F, Iwasaki H, Hosokawa K, Kobayashi I, Gomei Y, et al. Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells. Blood 2010;116: 1422-32.
    • (2010) Blood , vol.116 , pp. 1422-1432
    • Nakamura, Y.1    Arai, F.2    Iwasaki, H.3    Hosokawa, K.4    Kobayashi, I.5    Gomei, Y.6
  • 41
    • 77955599615 scopus 로고    scopus 로고
    • Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma (null) humanized mice
    • Shultz LD, Saito Y, Najima Y, Tanaka S, Ochi T, Tomizawa M, et al. Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma (null) humanized mice. Proc Natl Acad Sci U S A 2010;107: 13022-7.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13022-13027
    • Shultz, L.D.1    Saito, Y.2    Najima, Y.3    Tanaka, S.4    Ochi, T.5    Tomizawa, M.6
  • 42
    • 84871889126 scopus 로고    scopus 로고
    • Human long-term culture initiating cell assay
    • Liu M, Miller CL, Eaves CJ. Human long-term culture initiating cell assay. Methods Mol Biol 2013;946: 241-56.
    • (2013) Methods Mol Biol , vol.946 , pp. 241-256
    • Liu, M.1    Miller, C.L.2    Eaves, C.J.3
  • 43
    • 34548841921 scopus 로고    scopus 로고
    • MN1 overexpression induces acutemyeloid leukemia inmice and predicts ATRA resistance in patients with AML
    • Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, et al. MN1 overexpression induces acutemyeloid leukemia inmice and predicts ATRA resistance in patients with AML. Blood 2007;110: 1639-47.
    • (2007) Blood , vol.110 , pp. 1639-1647
    • Heuser, M.1    Argiropoulos, B.2    Kuchenbauer, F.3    Yung, E.4    Piper, J.5    Fung, S.6
  • 44
    • 84905741878 scopus 로고    scopus 로고
    • Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche
    • Hanoun M, Zhang D, Mizoguchi T, Pinho S, Pierce H, Kunisaki Y, et al. Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche. Cell Stem Cell 2014;15: 365-75.
    • (2014) Cell Stem Cell , vol.15 , pp. 365-375
    • Hanoun, M.1    Zhang, D.2    Mizoguchi, T.3    Pinho, S.4    Pierce, H.5    Kunisaki, Y.6
  • 45
    • 84905005330 scopus 로고    scopus 로고
    • Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
    • Arranz L, Sanchez-Aguilera A, Martin-Perez D, Isern J, Langa X, Tzankov A, et al. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms. Nature 2014;512: 78-81.
    • (2014) Nature , vol.512 , pp. 78-81
    • Arranz, L.1    Sanchez-Aguilera, A.2    Martin-Perez, D.3    Isern, J.4    Langa, X.5    Tzankov, A.6
  • 46
    • 84908587480 scopus 로고    scopus 로고
    • Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts
    • KrevvataM, Silva BC, Manavalan JS, Galan-DiezM, Kode A, Matthews BG, et al. Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts. Blood 2014;124: 2834-46.
    • (2014) Blood , vol.124 , pp. 2834-2846
    • KrevvataM Silva, B.C.1    Manavalan, J.S.2    Galan-DiezM Kode, A.3    Matthews, B.G.4
  • 47
    • 53349105777 scopus 로고    scopus 로고
    • Hematopoietic stem cells regulate mesenchymal stromal cell induction into osteoblasts thereby participating in the formation of the stem cell niche
    • Jung Y, Song J, Shiozawa Y, Wang J, Wang Z, Williams B, et al. Hematopoietic stem cells regulate mesenchymal stromal cell induction into osteoblasts thereby participating in the formation of the stem cell niche. Stem cells 2008;26: 2042-51.
    • (2008) Stem cells , vol.26 , pp. 2042-2051
    • Jung, Y.1    Song, J.2    Shiozawa, Y.3    Wang, J.4    Wang, Z.5    Williams, B.6
  • 48
    • 0030886656 scopus 로고    scopus 로고
    • Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabeticscid/scid mice
    • Conneally E, Cashman J, Petzer A, Eaves C. Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabeticscid/scid mice. Proc Natl Acad Sci U S A 1997;94: 9836-41.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9836-9841
    • Conneally, E.1    Cashman, J.2    Petzer, A.3    Eaves, C.4
  • 49
    • 84888212251 scopus 로고    scopus 로고
    • Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice
    • Cheung AM, Nguyen LV, Carles A, Beer P, Miller PH, Knapp DJ, et al. Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice. Blood 2013;122: 3129-37.
    • (2013) Blood , vol.122 , pp. 3129-3137
    • Cheung, A.M.1    Nguyen, L.V.2    Carles, A.3    Beer, P.4    Miller, P.H.5    Knapp, D.J.6


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