Glucosamine loaded injectable silk-in-silk integrated system modulate mechanical properties in bovine ex-vivo degenerated intervertebral disc model

Biomaterials

Volumn 55, Issue , 2015, Pages 64-83

  Murab, Sumit ^a,b   Samal, Juhi ^b   Shrivastava, Akshay ^b   Ray, Alok Ranjan ^a   Pandit, Abhay ^b   Ghosh, Sourabh ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Glucosamine; Injectable hydrogel; Intervertebral disc; Silk hollow microspheres

Indexed keywords

BIOMECHANICS; COMPRESSION TESTING; GLUCOSAMINE; MICROSPHERES; SILK; TISSUE; TISSUE REGENERATION;

HOLLOW MICROSPHERE; INJECTABLE HYDROGELS; INTEGRATED SYSTEMS; INTERVERTEBRAL DISC MODELS; INTERVERTEBRAL DISCS; NACETYL GLUCOSAMINE (GLCNAC); STRUCTURAL SUPPORT; SURGICAL PROCEDURES;

HYDROGELS;

AGGRECAN; COLLAGEN TYPE 2; GLUCOSAMINE; MICROSPHERE; MITOGEN ACTIVATED PROTEIN KINASE; N ACETYLGLUCOSAMINE; POLYSTYRENE; PROTEOGLYCAN; SILK; SMAD PROTEIN; BIOMATERIAL; HYDROGEL; POLYSTYRENE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; COMPRESSION; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG DELIVERY SYSTEM; DRUG RELEASE; EX VIVO STUDY; EXPERIMENTAL CATTLE; FLOW KINETICS; HUMAN; HUMAN CELL; HYDROGEL; IMMUNOHISTOLOGY; INTERVERTEBRAL DISK DEGENERATION; IONIC STRENGTH; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PHYSICAL PARAMETERS; POLYDISPERSITY INDEX; PRIORITY JOURNAL; PROTEIN FUNCTION; SPATIOTEMPORAL ANALYSIS; SURFACE PROPERTY; YOUNG MODULUS; ZETA POTENTIAL; ANIMAL; BOMBYX; BOVINE; CELL SURVIVAL; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION PROFILING; IN VITRO STUDY; INTERVERTEBRAL DISK; MATERIALS TESTING; MECHANICAL STRESS; METABOLISM; PATHOLOGY; REGENERATION; TRANSMISSION ELECTRON MICROSCOPY;

BOVINAE;

ANIMALS; BIOCOMPATIBLE MATERIALS; BOMBYX; CATTLE; CELL SURVIVAL; ELASTIC MODULUS; GENE EXPRESSION PROFILING; GLUCOSAMINE; HYDROGELS; IN VITRO TECHNIQUES; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MATERIALS TESTING; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MICROSPHERES; PARTICLE SIZE; POLYSTYRENES; PROTEOGLYCANS; REGENERATION; RHEOLOGY; SILK; STRESS, MECHANICAL;

EID: 84932610909     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.03.032     Document Type: Article

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