Silk-based biomaterials for sustained drug delivery

Journal of Controlled Release

Volumn 190, Issue , 2014, Pages 381-397

  Yucel, Tuna ^a,b   Lovett, Michael L ^a,b   Kaplan, David L ^a  

^a Tufts University   (United States)

^b Ekteino Laboratories   (United States)

Author keywords

Biocompatibility; Biodegradation; Biologics; Drugs; Mechanisms; Processing

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADATION; BIOLOGICAL MATERIALS; DRUG DELIVERY; MECHANICAL PROPERTIES; MECHANISMS; MICROBIOLOGY; MOLECULES; PROCESSING; PURIFICATION; SELF ASSEMBLY; SILK;

BIOLOGICS; CRYSTAL POLYMORPHISM; DRUG DELIVERY FORMULATIONS; DRUG DELIVERY SYSTEM; DRUGS; GENETIC MODIFICATIONS; MACROMOLECULAR DRUGS; STRUCTURAL HIERARCHIES;

SILK; DRUG PRODUCTS;

ADENOSINE; AMPICILLIN; BIOMATERIAL; BUPRENORPHINE; CEFAZOLIN; CLOPIDOGREL; COMPLEMENT COMPONENT C3; CORTISONE; DEXAMETHASONE; EMODIN; ERYTHROMYCIN; GENTAMICIN; HYDROCORTISONE; INDIGO CARMINE; METHYLPREDNISOLONE; PACLITAXEL; PENICILLIN DERIVATIVE; POLYMER; POLYVINYL ALCOHOL; PREDNISOLONE; PREDNISONE; PROPRANOLOL; RHODAMINE B; RIFAMPICIN; SALICYLIC ACID; SERICIN; SILK; SILK FIBROIN; TETRACYCLINE; THEOPHYLLINE; ETHYLENE OXIDE; MICROSPHERE; DELAYED RELEASE FORMULATION; HYDROGEL;

BIOCOMPATIBILITY; BIODEGRADATION; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; DRUG DELIVERY SYSTEM; DRUG STABILITY; ENZYMATIC DEGRADATION; GENE TARGETING; GOOD MANUFACTURING PRACTICE; HUMAN; HYDROGEL; MACROMOLECULE; MOLECULAR WEIGHT; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SUSTAINED DRUG RELEASE; TYMPANOSTOMY TUBE; AUTOCLAVE; DISINFECTION; DRUG APPROVAL; DRUG DIFFUSION; DRUG IMPLANT; DRUG RELEASE; ENCAPSULATION; FOOD AND DRUG ADMINISTRATION; GEL; GENE THERAPY; INSTRUMENT STERILIZATION; MICROGEL; PROTEIN PURIFICATION; THERMOSTABILITY; WATER VAPOR; CHEMISTRY; DELAYED RELEASE FORMULATION;

BIOCOMPATIBLE MATERIALS; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; HUMANS; HYDROGELS; SILK;

EID: 84906782250     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.05.059     Document Type: Review

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115. J. Cappello, J.W. Crissman, M. Crissman, F.A. Ferrari, G. Textor, O. Wallis, J.R. Whitledge, X. Zhou, D. Burman, L. Aukerman, and E.R. Stedronsky In-situ self-assembling protein polymer gel systems for administration, delivery, and release of drugs J. Control. Release 53 1998 105 117 (Pubitemid 28218694)
116. O. Bayraktar, O. Malay, Y. Ozgarip, and A. Batigun Silk fibroin as a novel coating material for controlled release of theophylline Eur. J. Pharm. Biopharm. 60 2005 373 381 (Pubitemid 40922834)
117. E.M. Pritchard, T. Valentin, D. Boison, and D.L. Kaplan Incorporation of proteinase inhibitors into silk-based delivery devices for enhanced control of degradation and drug release Biomaterials 32 2010 909 918
118. S.K. Cheema, A.S. Gobin, R. Rhea, G. Lopez-Berestein, R.A. Newman, and A.B. Mathur Silk fibroin mediated delivery of liposomal emodin to breast cancer cells Int. J. Pharm. 341 2007 221 229 (Pubitemid 47088100)
119. X. Wang, X. Zhang, J. Castellot, I. Herman, M. Iafrati, and D.L. Kaplan Controlled release from multilayer silk biomaterial coatings to modulate vascular cell responses Biomaterials 29 2008 894 903 (Pubitemid 350278534)
120. A. Wilz, E.M. Pritchard, T. Li, J.Q. Lan, D.L. Kaplan, and D. Boison Silk polymer-based adenosine release: therapeutic potential for epilepsy Biomaterials 29 2008 3609 3616
121. X. You, J.H. Chang, B.K. Ju, and J.J. Pak Rapidly dissolving fibroin microneedles for transdermal drug delivery Mater. Sci. Eng. C 31 2011 1632 1636
122. J.Y. Fang, J.P. Chen, Y.L. Leu, and H.Y. Wang Characterization and evaluation of silk protein hydrogels for drug delivery Chem. Pharm. Bull. (Tokyo) 54 2006 156 162
123. E.S. Gil, B. Panilaitis, E. Bellas, and D.L. Kaplan Functionalized silk biomaterials for wound healing Adv. Healthc. Mater. 2 2013 206 217
124. Y. Zhang, C. Wu, T. Luo, S. Li, X. Cheng, and R.J. Miron Synthesis and inflammatory response of a novel silk fibroin scaffold containing BMP7 adenovirus for bone regeneration Bone 51 2012 704 713
125. M. Hofer, G. Winter, and J. Myschik Recombinant spider silk particles for controlled delivery of protein drugs Biomaterials 33 2012 1554 1562
126. S. Hofmann, C.T. Foo, F. Rossetti, M. Textor, G. Vunjak-Novakovic, D.L. Kaplan, H.P. Merkle, and L. Meinel Silk fibroin as an organic polymer for controlled drug delivery J. Control. Release 111 2006 219 227 (Pubitemid 43290011)
127. P.C. Bessa, E.R. Balmayor, H.S. Azevedo, S. Nürnberger, M. Casal, M. Van Griensven, R.L. Reis, and H. Redl Silk fibroin microparticles as carriers for delivery of human recombinant BMPs. Physical characterization and drug release J. Tissue Eng. Regen. Med. 4 2010 349 355
128. C. Li, C. Vepari, H.J. Jin, H.J. Kim, and D.L. Kaplan Electrospun silk-BMP-2 scaffolds for bone tissue engineering Biomaterials 27 2006 3115 3124 (Pubitemid 43247585)
129. A. Schneider, X.Y. Wang, D.L. Kaplan, J.A. Garlick, and C. Egles Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing Acta Biomater. 5 2009 2570 2578
130. L. Uebersax, M. Mattotti, M. Papaloizos, H.P. Merkle, B. Gander, and L. Meinel Silk fibroin matrices for the controlled release of nerve growth factor (NGF) Biomaterials 28 2007 4449 4460 (Pubitemid 47225114)
131. S. Madduri, M. Papaloïzos, and B. Gander Trophically and topographically functionalized silk fibroin nerve conduits for guided peripheral nerve regeneration Biomaterials 31 2010 2323 2334
132. A.M. Hopkins, L. De Laporte, F. Tortelli, E. Spedden, C. Staii, T.J. Atherton, J.A. Hubbell, and D.L. Kaplan Silk hydrogels as soft substrates for neural tissue engineering Adv. Funct. Mater. 23 2013 5140 5149
133. V. Karageorgiou, L. Meinel, S. Hofmann, A. Malhotra, V. Volloch, and D. Kaplan Bone morphogenetic protein-2 decorated silk fibroin films induce osteogenic differentiation of human bone marrow stromal cells J. Biomed. Mater. Res. A 71 2004 528 537 (Pubitemid 39489907)
134. X. Wang, and D.L. Kaplan Functionalization of silk fibroin with NeutrAvidin and biotin Macromol. Biosci. 11 2011 100 110
135. H.B. Yan, Y.Q. Zhang, Y.L. Ma, and L.X. Zhou Biosynthesis of insulin-silk fibroin nanoparticles conjugates and in vitro evaluation of a drug delivery system J. Nanoparticle Res. 11 2009 1937 1946
136. Y.C. Lin, M. Ramadan, M. Hronik-Tupaj, D.L. Kaplan, B.J. Philips, W. Sivak, J.P. Rubin, and K.G. Marra Spatially controlled delivery of neurotrophic factors in silk fibroin-based nerve conduits for peripheral nerve repair Ann. Plast. Surg. 67 2011 147 155
137. R. Elia, D.R. Newhide, P.D. Pedevillano, G.R. Reiss, M.A. Firpo, E.W. Hsu, D.L. Kaplan, G.D. Prestwich, and R.A. Peattie Silk-hyaluronan-based composite hydrogels: a novel, securable vehicle for drug delivery J. Biomater. Appl. 27 2013 749 762
138. Y. Gu, L. Chen, H.L. Yang, Z.P. Luo, and T.S. Tang Evaluation of an injectable silk fibroin enhanced calcium phosphate cement loaded with human recombinant bone morphogenetic protein-2 in ovine lumbar interbody fusion J. Biomed. Mater. Res. A 97 A 2011 177 185
139. X. Wang, E. Wenk, X. Hu, G.R. Castro, L. Meinel, C. Li, H. Merkle, and D.L. Kaplan Silk coatings on PLGA and alginate microspheres for protein delivery Biomaterials 28 2007 4161 4169 (Pubitemid 47048382)
140. B.B. Mandal, J.K. Mann, and S.C. Kundu Silk fibroin/gelatin multilayered films as a model system for controlled drug release Eur. J. Pharm. Sci. 37 2009 160 171
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142. B.B. Mandal, and S.C. Kundu Calcium alginate beads embedded in silk fibroin as 3D dual drug releasing scaffolds Biomaterials 30 2009 5170 5177
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144. D.J. Hines, and D.L. Kaplan Mechanisms of controlled release from silk fibroin films Biomacromolecules 12 2011 804 812
145. C.C. Lin, and A.T. Metters Hydrogels in controlled release formulations: network design and mathematical modeling Adv. Drug Deliv. Rev. 58 2006 1379 1408
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151. D.J. Hines, and D.L. Kaplan Characterization of small molecule controlled release from silk films Macromol. Chem. Phys. 214 2013 280 294
152. P. Wongpanit, H. Ueda, Y. Tabata, and R. Rujiravanit In vitro and in vivo release of basic fibroblast growth factor using a silk fibroin scaffold as delivery carrier J. Biomater. Sci. Polym. Ed. 21 2010 1403 1419
153. E.M. Pritchard, P.B. Dennis, F. Omenetto, R.R. Naik, and D.L. Kaplan Review: physical and chemical aspects of stabilization of compounds in silk Biopolymers 97 2012 479 498
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160. P.B. Dennis, A.Y. Walker, M.B. Dickerson, D.L. Kaplan, and R.R. Naik Stabilization of organophosphorus hydrolase by entrapment in silk fibroin: formation of a robust enzymatic material suitable for surface coatings Biomacromolecules 13 2012 2037 2045
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166. Y. Takasu, H. Yamada, and K. Tsubouchi Extraction and chromatographic analysis of cocoon sericin of the silkworm, Bombyx mori J. Insect Biotechnol. Sericology 71 2002 151 156 (Pubitemid 36141365)
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