Sporothrix schenckii complex biology: Environment and fungal pathogenicity

Microbiology (United Kingdom)

Volumn 160, Issue , 2014, Pages 2352-2365

  Tellez M D ^a,b   Batista Duharte, A ^b,c   Portuondo, D ^b   Quinello, C ^b   Bonne Hernandez R ^d   Carlos, I Z ^b  

^a UNIVERSIDAD DE ORIENTE   (Cuba)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c Immunotoxicology Laboratory   (Cuba)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; CATALASE; CHEMICAL COMPOUND; ERGOSTEROL; MELANIN; METAL; NITROREDUCTASE; PROTEINASE; SIDEROPHORE; SUPEROXIDE DISMUTASE; VIRULENCE FACTOR; FUNGAL PROTEIN;

ARTICLE; CONTAMINATION; ENVIRONMENTAL FACTOR; ENZYME SYNTHESIS; FUNGAL VIRULENCE; GENETIC POLYMORPHISM; HOST PATHOGEN INTERACTION; HOST RESISTANCE; IMMUNOCOMPROMISED PATIENT; IMMUNOMODULATION; MICROBIOLOGY; NONHUMAN; OPPORTUNISTIC INFECTION; PHAGOCYTOSIS; PHYSICAL SENSITIVITY; PROTEIN EXPRESSION; SEX DIFFERENCE; SPOROTHRIX SCHENCKII; SPOROTRICHOSIS; ANIMAL; GENETICS; HUMAN; METABOLISM; PATHOGENICITY; PHYSIOLOGY; SPOROTHRIX; VIRULENCE;

ANIMALS; ENVIRONMENTAL MICROBIOLOGY; FUNGAL PROTEINS; HUMANS; SPOROTHRIX; SPOROTRICHOSIS; VIRULENCE;

EID: 84932173284     PISSN: 13500872     EISSN: 14652080     Source Type: Journal    
DOI: 10.1099/mic.0.081794-0     Document Type: Article

References (174)

1. Almeida-Paes, R., Frases, S., Fialho Monteiro, P. C., Gutierrez- Galhardo, M. C., Zancopé-Oliveira, R. M. & Nosanchuk, J. D. (2009). Growth conditions influence melanization of Brazilian clinical Sporothrix schenckii isolates. Microbes Infect 11, 554–562.
2. Alves, L. L., Travassos, L. R., Previato, J. O. & Mendonça-Previato, L. (1994). Novel antigenic determinants from peptidorhamnomannans of Sporothrix schenckii. Glycobiology 4, 281–288.
3. Alviano, C. S., Pereira, M. E. A., Souza, W., Oda, L. M. & Travassos, L. R. (1982). Sialic acids are surface components of Sporothrix schenckii yeast forms. FEMS Microbiol Lett 15, 223–228.
4. Alviano, C. S., Travassos, L. R. & Schauer, R. (1999). Sialic acids in fungi: a minireview. Glycoconj J 16, 545-554.
5. Anahid, S., Yaghmaei, S. & Ghobadinejad, Z. (2011). Heavy metal tolerance of fungi. Scientia Iranica 18, 502-508.
6. Aung, A. K., Teh, B. M., McGrath, C. & Thompson, P. J. (2013). Pulmonary sporotrichosis: case series and systematic analysis of literature on clinico-radiological patterns and management outcomes. Med Mycol 51, 534-544.
7. Aviv, G., Tsyba, K., Steck, N., Salmon-Divon, M., Cornelius, A., Rahav, G., Grassl, G. A. & Gal-Mor, O. (2014). A unique megaplasmid contributes to stress tolerance and pathogenicity of an emergent Salmonella enterica serovar Infantis strain. Environ Microbiol 16, 977-994.
8. Basaga, H. S. (1990). Biochemical aspects of free radicals. Biochem Cell Biol 68, 989-998.
9. Bates, M. L., Reid, W. W. & White, J. D. (1976). Duality of pathways in the oxidation of ergosterol to its peroxide in vivo. J Chem Soc Chem Commun 44-45.
10. Baumgardner, D. J. (2012). Soil-related bacterial and fungal infections. J Am Board Family Med 25, 734-744.
11. Borges, T. S., Rossi, C. N., Fedullo, J. D., Taborda, C. P. & Larsson, C. E. (2013). Isolation of Sporothrix schenckii from the claws of domestic cats (indoor and outdoor) and in captivity in São Paulo (Brazil). Mycopathologia 176, 129-137.
12. Bustamante, B. & Campos, P. E. (2001). Endemic sporotrichosis. Curr Opin Infect Dis 14, 145-149.
13. Carlos, I. Z., Zini, M. M., Sgarbi, D. B., Angluster, J., Alviano, C. S. & Silva, C. L. (1994). Disturbances in the production of interleukin-1 and tumor necrosis factor in disseminated murine sporotrichosis. Mycopathologia 127, 189-194.
14. Carlos, I. Z., Sgarbi, D. B., Santos, G. C. & Placeres, M. C. (2003). Sporothrix schenckii lipid inhibits macrophage phagocytosis: involvement of nitric oxide and tumour necrosis factor-a. Scand J Immunol 57, 214-220.
15. Carlos, I. Z., Sassá, M. F., da Graça Sgarbi, D. B., Placeres, M. C. & Maia, D. C. (2009). Current research on the immune response to experimental sporotrichosis. Mycopathologia 168, 1-10.
16. Carrada-Bravo, T. & Olvera-Macías, M. I. (2013). New observations on the ecology and epidemiology of Sporothrix schenckii and sporotrichosis. Rev Latinoamer Patol Clin 60, 5-24.
17. Casadevall, A., Steenbergen, J. N. & Nosanchuk, J. D. (2003). ‘Ready made’ virulence and ‘dual use’ virulence factors in pathogenic environmental fungi-the Cryptococcus neoformans paradigm. Curr Opin Microbiol 6, 332-337.
18. Castellani, A. (1967). Maintenance and cultivation of the common pathogenic fungi of man in sterile distilled water. Further researches. J Trop Med Hyg 70, 181-184.
19. Castro, R. A., Kubitschek-Barreira, P. H., Teixeira, P. A., Sanches, G. F., Teixeira, M. M., Quintella, L. P., Almeida, S. R., Costa, R. O., Camargo, Z. P. & other authors (2013). Differences in cell morphometry, cell wall topography and gp70 expression correlate with the virulence of Sporothrix brasiliensis clinical isolates. PLoS ONE 8, e75656.
20. Cerniglia, C. E. (1997). Fungal metabolism of polycyclic aromatic hydrocarbons: past, present and future applications in bioremediation. J Ind Microbiol Biotechnol 19, 324-333.
21. Chao, H. J., Chan, C. C., Rao, C. Y., Lee, C. T., Chuang, Y. C., Chiu, Y. H., Hsu, H. H. & Wu, Y. H. (2012). The effects of transported Asian dust on the composition and concentration of ambient fungi in Taiwan. Int J Biometeorol 56, 211-219.
22. Chaturvedi, V. P., Randhawa, H. S., Chaturvedi, S. & Khan, Z. U. (1988). In vitro interactions between Blastomyces dermatitidis and other zoopathogenic fungi. Can J Microbiol 34, 897-900.
23. Colon-Colon, W. & Rodriguez-del Valle, N. (1993). Studies on phase transitions in Sporothrix schenckii: possible involvement of protein kinase C. Dimorphic Fungi Biol. Med. 225-239.
24. Cooke, W. B. & Foter, M. J. (1958). Fungi in used bedding materials. Appl Microbiol 6, 169-173.
25. Criseo, G., Malara, G., Romeo, O. & Puglisi Guerra, A. (2008). Lymphocutaneous sporotrichosis in an immunocompetent patient: a case report from extreme southern Italy. Mycopathologia 166, 159-162.
26. Cunningham, K. M., Bulmer, G. S. & Rhoades, E. R. (1979). Phagocytosis and intracellular fate of Sporothrix schenckii. J Infect Dis 140, 815-817.
27. da Graça Sgarbi, D. B., da Silva, A. J. R., Carlos, I. Z., Silva, C. L., Angluster, J. & Alviano, C. S. (1997). Isolation of ergosterol peroxide and its reversion to ergosterol in the pathogenic fungus Sporothrix schenckii. Mycopathologia 139, 9-14.
28. Da Rosa, D., Gezuele, E., Calegari, L. & Goñi, F. (2009). Excretion-secretion products and proteases from live Sporothrix schenckii yeast phase: immunological detection and cleavage of human IgG. Rev Inst Med Trop Sao Paulo 51, 1-7.
29. Davies, B., Chattings, L. S. & Edwards, S. W. (1991). Superoxide generation during phagocytosis by Acanthamoeba castellanii: similarities to the respiratory burst of immune phagocytes. J Gen Microbiol 137, 705-710.
30. de Beurmann, L. & Gougerot, H. (1912). Les Sporotrichoses. Paris: Felix Alcan.
31. de Capriles, C. H., Essayag, S. M., Lander, A. & Camacho, R. (1993). Experimental pathogenicity of Sporothrix schenckii preserved in water (Castellani). Mycopathologia 122, 129-133.
32. de Hoog, G. S. (1974). The genera Blastobotrys, Sporothrix, Calcarisporium and Calcarisporiella gen. nov. Stud Mycol 7, 1-84.
33. de Lima Barros, M. B., Costa, D. L., Schubach, T. M., do Valle, A. C., Lorenzi, N. P., Teixeira, J. L. & Schubach, A. O. (2008). Endemic of zoonotic sporotrichosis: profile of cases in children. Pediatr Infect Dis J 27, 246-250.
34. de Lima Barros, M. B., Schubach, T. P., Coll, J. O., Gremião, I. D., Wanke, B. & Schubach, A. (2010). [Sporotrichosis: development and challenges of an epidemic]. Rev Panam Salud Publica 27, 455-460 (in Portuguese).
35. de Lima Barros, M. B., de Almeida Paes, R. & Schubach, A. O. (2011). Sporothrix schenckii and sporotrichosis. ClinMicrobiol Rev 24, 633-654.
36. de Moraes, Borba, C., da Silva, A. M. & de Oliveira, P. C. (1992). Long-time survival and morphological stability of preserved Sporothrix schenckii strains. Mycoses 35, 185-188.
37. de Souza Lacerda, C. M., do Nascimento Martins, E. M., de Resende, M. A. & de Andrade, A. S. R. (2011). Gamma radiation effects on Sporothrix schenckii yeast cells. Mycopathologia 171, 395-401.
38. Dias, N. M., Oliveira, M. M. E., Portela, M. A., Santos, C., Zancope-Oliveira, R. M. & Lima, N. (2011). Sporotrichosis caused by Sporothrix mexicana, Portugal. Emerg Infect Dis 17, 1975-1976.
39. Dixon, D. M., Salkin, I. F., Duncan, R. A., Hurd, N. J., Haines, J. H., Kemna, M. E. & Coles, F. B. (1991). Isolation and characterization of Sporothrix schenckii from clinical and environmental sources associated with the largest U.S. epidemic of sporotrichosis. J Clin Microbiol 29, 1106-1113.
40. Dunstan, R. W., Langham, R. F., Reimann, K. A. & Wakenell, P. S. (1986). Feline sporotrichosis: a report of five cases with transmission to humans. J Am Acad Dermatol 15, 37-45.
41. Edwards, C., Reuther, W. L., III & Greer, D. L. (2000). Disseminated osteoarticular sporotrichosis: treatment in a patient with acquired immunodeficiency syndrome. South Med J 93, 803-806.
42. Eisenman, H. C. & Casadevall, A. (2012). Synthesis and assembly of fungal melanin. Appl Microbiol Biotechnol 93, 931-940.
43. Feeney, K. T., Arthur, I. H., Whittle, A. J., Altman, S. A. & Speers, D. J. (2007). Outbreak of sporotrichosis, Western Australia. Emerg Infect Dis 13, 1228-1231.
44. Fernandes, K. S., Neto, E. H., Brito, M. M., Silva, J. S., Cunha, F. Q. & Barja-Fidalgo, C. (2008). Detrimental role of endogenous nitric oxide in host defence against Sporothrix schenckii. Immunology 123, 469-479.
45. Fernandes, G. F., Do Amaral, C. C., Sasaki, A., Godoy, P. M. & De Camargo, Z. P. (2009). Heterogeneity of proteins expressed by Brazilian Sporothrix schenckii isolates. Med Mycol 47, 855-861.
46. Fernandes, G. F., dos Santos, P. O., Rodrigues, A. M., Sasaki, A. A., Burger, E. & de Camargo, Z. P. (2013). Characterization of virulence profile, protein secretion and immunogenicity of different Sporothrix schenckii sensu stricto isolates compared with S. globosa and S. brasiliensis species. Virulence 4, 241-249.
47. Fernández-Silva, F., Capilla, J., Mayayo, E. & Guarro, J. (2012). Virulence of Sporothrix luriei in a murine model of disseminated infection. Mycopathologia 173, 245-249.
48. Figueiredo, C. C., Deccache, P. M., Lopes-Bezerra, L. M. & Morandi, V. (2007). TGF-b1 induces transendothelial migration of the pathogenic fungus Sporothrix schenckii by a paracellular route involving extracellular matrix proteins. Microbiology 153, 2910-2921.
49. Freitas, D. F., de Siqueira Hoagland, B., do Valle, A. C., Fraga, B. B., de Barros, M. B., de Oliveira Schubach, A., de Almeida-Paes, R., Cuzzi, T., Rosalino, C. M. & other authors (2012). Sporotrichosis in HIV-infected patients: report of 21 cases of endemic sporotrichosis in Rio de Janeiro, Brazil. Med Mycol 50, 170-178.
50. Gadd, G. M. (1993). Interactions of fungi with toxic metals. New Phytol 124, 25-60.
51. Galhardo, M. C. G., Silva, M. T. T., Lima, M. A., Nunes, E. P., Schettini, L. E. C., de Freitas, R. F., de Almeida Paes, R., de Sousa Neves, E. & do Valle, A. C. F. (2010). Sporothrix schenckii meningitis in AIDS during immune reconstitution syndrome. J Neurol Neurosurg Psychiatry 81, 696-699.
52. Gauthier, G. & Klein, B. S. (2008). Insights into fungal morphogenesis and immune evasion: fungal conidia, when situated in mammalian lungs, may switch from mold to pathogenic yeasts or spore-forming spherules. Microbe Wash DC 3, 416-423.
53. Gessler, N. N., Egorova, A. S. & Belozerskaya, T. A. (2014). Melanin pigments of fungi under extreme environmental conditions. Appl Biochem Microbiol 50, 105-113.
54. Gewehr, P., Jung, B., Aquino, V., Manfro, R. C., Spuldaro, F., Rosa, R. G. & Goldani, L. Z. (2013). Sporotrichosis in renal transplant patients. Can J Infect Dis Med Microbiol 24, e47-e49.
55. Ghosh, A., Maity, P. K., Hemashettar, B. M., Sharma, V. K. & Chakrabarti, A. (2002). Physiological characters of Sporothrix schenckii isolates. Mycoses 45, 449-454.
56. Gómez, B. L. & Nosanchuk, J. D. (2003). Melanin and fungi. Curr Opin Infect Dis 16, 91-96.
57. Gostincˇ ar, C., Grube, M. & Gunde-Cimerman, N. (2011). Evolution of fungal pathogens in domestic environments? Fungal Biol 115, 1008-1018.
58. Gürcan, S., Konuk, E., Kilic¸, H., Otkun, M. & Ener, B. (2007). Sporotrichosis, a disease rarely reported from Turkey, and an overview of Turkish literature. Mycoses 50, 426-429.
59. Guzman-Beltran, S., Perez-Torres, A., Coronel-Cruz, C. & Torres-Guerrero, H. (2012). Phagocytic receptors on macrophages distinguish between different Sporothrix schenckii morphotypes. Microbes Infect 14, 1093-1101.
60. Haddad, V., Jr, Miot, H. A., Bartoli, L. D., Cardoso, A. C. & Camargo, R. P. (2002a). Cutaneous sporotricosis associated with a puncture in the dorsal fin of a fish (Tilapia sp.): report of a case. Medical Mycol 40, 425-427.
61. Haddad V., Miot, H. A., Bartoli, L. D., De Chiara, A. C. & Pires, R. M. C. (2002b). Localized lymphatic sporotrichosis after fishinduced injury (Tilapia sp.). Med Mycol 40, 425-427.
62. Hay, R. J. & Morris-Jones, R. (2008). Outbreaks of sporotrichosis. Curr Opin Infect Dis 21, 119-121.
63. Hektoen, L. & Perkins, C. F. (1900). Refractory subcutaneous abscesses caused by Sporothrix schenckii: a new pathogenic fungus. J Exp Med 5, 77-89.
64. Hernández-Santos, N. & Gaffen, S. L. (2012). Th17 cells in immunity to Candida albicans. Cell Host Microbe 11, 425-435.
65. Hou, B., Zhang, Z., Zheng, F. & Liu, X. (2013). Molecular cloning, characterization and differential expression of DRK1 in Sporothrix schenckii. Int J Mol Med 31, 99-104.
66. Jarosławiecka, A. & Piotrowska-Seget, Z. (2014). Lead resistance in micro-organisms. Microbiology 160, 12-25.
67. Kacprzak, M. & Malina, G. (2005). The tolerance and Zn2+, Ba2+ and Fe3+ accumulation by Trichoderma atroviride and Mortierella exigua isolated from contaminated soil. Can J Soil Sci 85, 283-290.
68. Kaplan, J., McVey Ward, D., Crisp, R. J. & Philpott, C. C. (2006). Irondependent metabolic remodeling in S. cerevisiae. Biochim Biophys Acta 1763, 646-651.
69. Kauffman, C. A. (1999). Sporotrichosis. Clin Infect Dis 29, 231-237.
70. Kazanas, N. (1987). Pathogenic fungi isolated from desiccated mushrooms, seaweed, anchovies and rice sticks imported from the Orient. J Food Protection 50, 933-939.
71. Kitajima, Y. (2000). [Structural and biochemical characteristics of pathogenic fungus: cell walls, lipids and dimorphism, and action modes of antifungal agents]. Nippon Ishinkin Gakkai Zasshi 41, 211-217 (in Japanese).
72. Klein, B. S. & Tebbets, B. (2007). Dimorphism and virulence in fungi. Curr Opin Microbiol 10, 314-319.
73. Kosman, D. J. (2003). Molecular mechanisms of iron uptake in fungi. Mol Microbiol 47, 1185-1197.
74. Lee, B. U., Park, S. C., Cho, Y. S., Kahng, H. Y. & Oh, K. H. (2008). Expression and characterization of the TNT nitroreductase of Pseudomonas sp. HK-6 in Escherichia coli. Curr Microbiol 56, 386-390.
75. Lima, O. C., Figueiredo, C. C., Pereira, B. A., Coelho, M. G., Morandi, V. & Lopes-Bezerra, L. M. (1999). Adhesion of the human pathogen Sporothrix schenckii to several extracellular matrix proteins. Braz J Med Biol Res 32, 651-657.
76. Lima, O. C., Figueiredo, C. C., Previato, J. O., Mendonça-Previato, L., Morandi, V. & Bezerra, L. M. L. (2001). Involvement of fungal cell wall components in adhesion of Sporothrix schenckii to human fibronectin. Infect Immun 69, 6874-6880.
77. Lima, O. C., Bouchara, J. P., Renier, G., Marot-Leblond, A., Chabasse, D. & Lopes-Bezerra, L. M. (2004). Immunofluorescence and flow cytometry analysis of fibronectin and laminin binding to Sporothrix schenckii yeast cells and conidia. Microb Pathog 37, 131-140.
78. Liu, X. & Lin, X. (2001). A case of cutaneous disseminated sporotrichosis. J Dermatol 28, 95-99.
79. Lloret, A., Hartmann, K., Pennisi, M. G., Ferrer, L., Addie, D., Belák, S., Boucraut-Baralon, C., Egberink, H., Frymus, T. & other authors (2013). Sporotrichosis in cats: ABCD guidelines on prevention and management. J Feline Med Surg 15, 619-623.
80. Lopes-Bezerra, L. M., Schubach, A. & Costa, R. O. (2006). Sporothrix schenckii and sporotrichosis. An Acad Bras Cienc 78, 293-308.
81. López-Esparza, A., Álvarez-Vargas, A., Mora-Montes, H. M., Hernández-Cervantes, A., Del Carmen Cano-Canchola M. & Flores-Carreón, A. (2013). Isolation of Sporothrix schenckii GDA1 and functional characterization of the encoded guanosine diphosphatase activity. Arch Microbiol 195, 499-506.
82. López-Romero, E., del Rocío Reyes-Montes, M., Pérez-Torres, A., Ruiz-Baca, E., Villagómez-Castro, J. C., Mora-Montes, H. M., Flores-Carreón, A. & Toriello, C. (2011). Sporothrix schenckii complex and sporotrichosis, an emerging health problem. Future Microbiol 6, 85-102.
83. Madrid, H., Cano, J., Gene´, J., Bonifaz, A., Toriello, C. & Guarro, J. (2009). Sporothrix globosa, a pathogenic fungus with widespread geographical distribution. Rev Iberoam Micol 26, 218-222.
84. Madrid, I. M., Xavier, M. O., Mattei, A. S., Fernandes, C. G., Guim, T. N., Santin, R., Schuch, L. F. D., Nobre, M. O. & Araújo Meireles, M. C. (2010). Role of melanin in the pathogenesis of cutaneous sporotrichosis. Microbes Infect 12, 162-165.
85. Marimon, R., Gené, J., Cano, J., Trilles, L., Dos Santos Lazéra, M. & Guarro, J. (2006). Molecular phylogeny of Sporothrix schenckii. J Clin Microbiol 44, 3251-3256.
86. Marimon, R., Cano, J., Gene´, J., Sutton, D. A., Kawasaki, M. & Guarro, J. (2007). Sporothrix brasiliensis, S. globosa, and S. mexicana, three new Sporothrix species of clinical interest. J Clin Microbiol 45, 3198-3206.
87. Marimon, R., Gené, J., Cano, J. & Guarro, J. (2008a). Sporothrix luriei: a rare fungus from clinical origin. Med Mycol 46, 621-625.
88. Marimon, R., Serena, C., Gene´, J., Cano, J. & Guarro, J. (2008b). In vitro antifungal susceptibilities of five species of Sporothrix. Antimicrob Agents Chemother 52, 732-734.
89. Mendoza, M., Alvarado, P., Díaz de Torres, E., Lucena, L. & de Albornoz, M. C. (2005). [Physiological comportment and in vitro sensitivity of Sporothrix schenckii isolates maintained for 18 years by two preservation methods]. Rev Iberoam Micol 22, 151-156 (in Spanish).
90. Monod, M., Capoccia, S., Léchenne, B., Zaugg, C., Holdom, M. & Jousson, O. (2002). Secreted proteases from pathogenic fungi. Int J Med Microbiol 292, 405-419.
91. Mora-Montes, H. M., Ponce-Noyola, P., Villagómez-Castro, J. C., Gow, N. A. R., Flores-Carreón, A. & López-Romero, E. (2009). Protein glycosylation in Candida. Future Microbiol 4, 1167-1183.
92. Morehart, A. L. & Larsh, H. W. (1967). Laboratory examination of organic fungicides against zoopathogenic fungi in soil. Appl Microbiol 15, 1248-1251.
93. Morris-Jones, R., Youngchim, S., Gomez, B. L., Aisen, P., Hay, R. J., Nosanchuk, J. D., Casadevall, A. & Hamilton, A. J. (2003). Synthesis of melanin-like pigments by Sporothrix schenckii in vitro and during mammalian infection. Infect Immun 71, 4026-4033.
94. Nascimento, R. C. & Almeida, S. R. (2005). Humoral immune response against soluble and fractionate antigens in experimental sporotrichosis. Immun Med Microb 43, 241-247.
95. Nascimento, R. C., Espíndola, N. M., Castro, R. A., Teixeira, P. A., Loureiro y Penha, C. V., Lopes-Bezerra, L. M. & Almeida, S. R. (2008). Passive immunization with monoclonal antibody against a 70-kDa putative adhesin of Sporothrix schenckii induces protection in murine sporotrichosis. Eur J Immunol 38, 3080-3089.
96. Negrini, T. de C., Ferreira, L. S., Alegranci, P., Arthur, R. A., Sundfeld, P. P., Maia, D. C. G, Spolidorio, L. C. & Carlos, I. Z. (2013). Role of TLR-2 and fungal surface antigens on innate immune response against Sporothrix schenckii. Immunol Invest 42, 36-48.
97. Negrini, T. de C., Ferreira, L. S., Arthur, R. A., Alegranci, P., Placeres, M. C. P., Spolidorio, L. C. & Carlos, I. Z. (2014). Influence of TLR-2 in the immune response in the infection induced by fungus Sporothrix schenckii. Immunol Invest 43, 370-390.
98. Nemecek, J. C., Wüthrich, M. & Klein, B. S. (2006). Global control of dimorphism and virulence in fungi. Science 312, 583-588.
99. Niedbala, W., Cai, B., Liu, H., Pitman, N., Chang, L. & Liew, F. Y. (2007). Nitric oxide induces CD4+CD25+ Foxp32 regulatory T cells from CD4+CD252 T cells via p53, IL-2, and OX40. Proc Natl Acad Sci U S A 104, 15478-15483.
100. Niedbala, W., Alves-Filho, J. C., Fukada, S. Y., Vieira, S. M., Mitani, A., Sonego, F., Mirchandani, A., Nascimento, D. C., Cunha, F. Q. & Liew, F. Y. (2011). Regulation of type 17 helper T-cell function by nitric oxide during inflammation. Proc Natl Acad Sci U S A 108, 9220-9225.
101. Niedbala, W., Besnard, A. G., Jiang, H. R., Alves-Filho, J. C., Fukada, S. Y., Nascimento, D., Mitani, A., Pushparaj, P., Alqahtani, M. H. & Liew, F. Y. (2013). Nitric oxide-induced regulatory T cells inhibit Th17 but not Th1 cell differentiation and function. J Immunol 191, 164-170.
102. Noriega, C. T., Garay, R. R., Sabanero, G., Basurto, R. T. & López, M. S. (1993). [Sporothrix schenckii: cultures in different soils]. Rev Latinoam Microbiol 35, 191-194 (in Spanish).
103. Nosanchuk, J. D. & Casadevall, A. (2006). Impact of melanin on microbial virulence and clinical resistance to antimicrobial compounds. Antimicrob Agents Chemother 50, 3519-3528.
104. Nusbaum, B. P., Gulbas, N. & Horwitz, S. N. (1983). Sporotrichosis acquired from a cat. J Am Acad Dermatol 8, 386-391.
105. Oda, L. M., Kubelka, C. F., Alviano, C. S. & Travassos, L. R. (1983). Ingestion of yeast forms of Sporothrix schenckii by mouse peritoneal macrophages. Infect Immun 39, 497-504.
106. Ojeda, T., Rodríguez-Pichardo, A., Suárez, A. I. & Camacho, F. M. (2011). [Sporotrichosis in Seville (Spain)]. Enferm Infecc Microbiol Clin 29, 233-234 (in Spanish).
107. Oliveira, M. M. E., Almeida-Paes, R., Gutierrez-Galhardo, M. C. & Zancope-Oliveira, R. M. (2014). Molecular identification of the Sporothrix schenckii complex. Rev Iberoam Micol 31, 2-6.
108. Pasarell, L. & McGinnis, M. R. (1992). Viability of fungal cultures maintained at 270uC. J Clin Microbiol 30, 1000-1004.
109. Pečiulyte˙, D. (2010). Effect of long-term industrial pollution on microorganisms in soil of deciduous forests situated along a pollution gradient next to a fertilizer factory 3. Species diversity and community structure of soil fungi. Ekologija 56, 132-143.
110. Pérez-Sánchez, L., González, E., Colón-Lorenzo, E. E., González-Velázquez, W., González-Méndez, R. & Rodríguez-del Valle, N. (2010). Interaction of the heterotrimeric G protein alpha subunit SSG-1 of Sporothrix schenckii with proteins related to stress response and fungal pathogenicity using a yeast two-hybrid assay. BMC Microbiol 10, 317.
111. Pietrella, D., Pandey, N., Gabrielli, E., Pericolini, E., Perito, S., Kasper, L., Bistoni, F., Cassone, A., Hube, B. & Vecchiarelli, A. (2013). Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome. Eur J Immunol 43, 679-692.
112. Prenafeta-Boldú, F. X., Summerbell, R. & de Hoog, G. S. (2006). Fungi growing on aromatic hydrocarbons: biotechnology’s unexpected encounter with biohazard? FEMS Microbiol Rev 30, 109-130.
113. Ramos-e-Silva, M., Lima, C. M., Schechtman, R. C., Trope, B. M. & Carneiro, S. (2012). Systemic mycoses in immunodepressed patients (AIDS). Clin Dermatol 30, 616-627.
114. Ranjana, K. H., Chakrabarti, A., Kulachandra, M., Lokendra, K. & Devendra, H. (2001). Sporotrichosis in Manipur: report of two cases. Indian J Dermatol Venereol Leprol 67, 86-88.
115. Read, S. I. & Sperling, L. C. (1982). Feline sporotrichosis. Transmission to man. Arch Dermatol 118, 429-431.
116. Reed, K. D., Moore, F. M., Geiger, G. E. & Stemper, M. E. (1993). Zoonotic transmission of sporotrichosis: case report and review. Clin Infect Dis 16, 384-387.
117. Rivera-Rodríguez, N. & Rodríguez-del Valle, N. (1992). Effects of calcium ions on the germination of Sporothrix schenckii conidia. J Med Vet Mycol 30, 185-195.
118. Rocha, M. M., Dassin, T., Lira, R., Lima, E. L., Severo, L. C. & Londero, A. T. (2001). Sporotrichosis in patient with AIDS: report of a case and review. Rev Iberoam Micol 18, 133-136.
119. Rodrigues, A. M., de Hoog, S. & de Camargo, Z. P. (2013a). Emergence of pathogenicity in the Sporothrix schenckii complex. Med Mycol 51, 405-412.
120. Rodrigues, A. M., de Melo Teixeira, M., de Hoog, G. S., Schubach, T. M., Pereira, S. A., Fernandes, G. F., Bezerra, L. M., Felipe, M. S. & de Camargo, Z. P. (2013b). Phylogenetic analysis reveals a high prevalence of Sporothrix brasiliensis in feline sporotrichosis outbreaks. PLoS Negl Trop Dis 7, e2281.
121. Rodriguez-Caban, J., Gonzalez-Velazquez, W., Perez-Sanchez, L., Gonzalez-Mendez, R. & Rodriguez-del Valle, N. (2011). Calcium/ calmodulin kinase1 and its relation to thermotolerance and HSP90 in Sporothrix schenckii: an RNAi and yeast two-hybrid study. BMC Microbiol 11, 162.
122. Romeo, O. & Criseo, G. (2013). What lies beyond genetic diversity in Sporothrix schenckii species complex? New insights into virulence profiles, immunogenicity and protein secretion in S. schenckii sensu stricto isolates. Virulence 4, 203-206.
123. Romeo, O., Scordino, F. & Criseo, G. (2011). New insight into molecular phylogeny and epidemiology of Sporothrix schenckii species complex based on calmodulin-encoding gene analysis of Italian isolates. Mycopathologia 172, 179-186.
124. Romero-Martinez, R., Wheeler, M., Guerrero-Plata, A., Rico, G. & Torres-Guerrero, H. (2000). Biosynthesis and functions of melanin in Sporothrix schenckii. Infect Immun 68, 3696-3703.
125. Rosas, A. L. & Casadevall, A. (1997). Melanization affects susceptibility of Cryptococcus neoformans to heat and cold. FEMS Microbiol Lett 153, 265-272.
126. Rosas, A. L. & Casadevall, A. (2001). Melanization decreases the susceptibility of Cryptococcus neoformans to enzymatic degradation. Mycopathologia 151, 53-56.
127. Ruiz-Baca, E., Toriello, C., Pérez-Torres, A., Sabanero-Lopez, M., Villagómez-Castro, J. C. & López-Romero, E. (2009). Isolation and some properties of a glycoprotein of 70 kDa (Gp70) from the cell wall of Sporothrix schenckii involved in fungal adherence to dermal extracellular matrix. Med Mycol 47, 185-196.
128. Sampermans, S., Mortier, J. & Soares, E. V. (2005). Flocculation onset in Saccharomyces cerevisiae: the role of nutrients. J Appl Microbiol 98, 525-531.
129. Sasaki, A. A., Fernandes, G. F., Rodrigues, A. M., Lima, F. M., Marini, M. M., Feitosa, L. dos S., de Melo Teixeira, M., Felipe, M. S. S., da Silveira, J. F. & de Camargo, Z. P. (2014). Chromosomal polymorphism in the Sporothrix schenckii complex. PLoS ONE 9, e86819.
130. Sassá, M. F., Ferreira, L. S., de Abreu Ribeiro, L. C. & Carlos, I. Z. (2012). Immune response against Sporothrix schenckii in TLR-4-deficient mice. Mycopathologia 174, 21-30.
131. Schaible, U. E. & Kaufmann, S. H. (2004). Iron and microbial infection. Nat Rev Microbiol 2, 946-953.
132. Schenck, B. R. (1898). On refractory subcutaneous abscesses caused by a fungus possibly related to the Sporotricha. Bull Johns Hopkins Hosp 9, 286-290.
133. Schubach, T. M., Valle, A. C., Gutierrez-Galhardo, M. C., Monteiro, P. C., Reis, R. S., Zancopé-Oliveira, R. M., Marzochi, K. B. & Schubach, A. (2001). Isolation of Sporothrix schenckii from the nails of domestic cats (Felis catus). Med Mycol 39, 147-149.
134. Schubach, T. M. P., de Oliveira Schubach, A., dos Reis, R. S., Cuzzi-Maya, T., Blanco, T. C. M., Monteiro, D. F., de Lima, Barros, M. B., Brustein, R., Zancopé-Oliveira, R. M. & other authors (2002). Sporothrix schenckii isolated from domestic cats with and without sporotrichosis in Rio de Janeiro, Brazil. Mycopathologia 153, 83-86.
135. Scott, E. N. & Muchmore, H. G. (1989). Immunoblot analysis of antibody responses to Sporothrix schenckii. J ClinMicrobiol 27, 300-304.
136. Serrano, S. & Rodríguez-del Valle, N. (1990). Calcium uptake and efflux during the yeast to mycelium transition in Sporothrix schenckii. Mycopathologia 112, 1-9.
137. Silva-Vergara, M. L., Maneira, F. R., De Oliveira, R. M., Santos, C. T., Etchebehere, R. M. & Adad, S. J. (2005). Multifocal sporotrichosis with meningeal involvement in a patient with AIDS. Med Mycol 43, 187-190.
138. Silva-Vergara, M. L., de Camargo, Z. P., Silva, P. F., Abdalla, M. R., Sgarbieri, R. N., Rodrigues, A. M., dos Santos, K. C., Barata, C. H. & Ferreira-Paim, K. (2012). Disseminated Sporothrix brasiliensis infection with endocardial and ocular involvement in an HIV-infected patient. Am J Trop Med Hyg 86, 477-480.
139. Smilack, J. D. (1993). Zoonotic transmission of sporotrichosis. Clin Infect Dis 17, 1075-1076.
140. Staib, F. & Grosse, G. (1983). Isolation of Sporothrix schenckii from the floor of an indoor swimming pool. Zentralbl Bakteriol Mikrobiol Hyg B 177, 499-506.
141. Steenbergen, J. N., Nosanchuk, J. D., Malliaris, S. D. & Casadevall, A. (2003). Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum. Infect Immun 71, 4862-4872.
142. Steenbergen, J. N., Nosanchuk, J. D., Malliaris, S. D. & Casadevall, A. (2004). Interaction of Blastomyces dermatitidis, Sporothrix schenckii, and Histoplasma capsulatum with Acanthamoeba castellanii. Infect Immun 72, 3478-3488.
143. Stopiglia, C. D., Carissimi, M., Daboit, T. C., Stefani, V., Corbellini, V. A. & Scroferneker, M. L. (2013). Application of 6-nitrocoumarin as a substrate for the fluorescent detection of nitroreductase activity in Sporothrix schenckii. Rev Inst Med Trop Sao Paulo 55, 353-356.
144. Taborda, C. P., da Silva, M. B., Nosanchuk, J. D. & Travassos, L. R. (2008). Melanin as a virulence factor of Paracoccidioides brasiliensis and other dimorphic pathogenic fungi: a minireview. Mycopathologia 165, 331-339.
145. Teixeira, P. A., de Castro, R. A., Nascimento, R. C., Tronchin, G., Torres, A. P., Lazéra, M., de Almeida, S. R., Bouchara, J. P., Loureiro y Penha C. V. & Lopes-Bezerra, L. M. (2009). Cell surface expression of adhesins for fibronectin correlates with virulence in Sporothrix schenckii. Microbiology 155, 3730-3738.
146. Torres-Guerrero, H. & Arenas-López, G. (1998). UV irradiation induced high frequency of colonial variants with altered morphology in Sporothrix schenckii. Med Mycol 36, 81-87.
147. Travassos, L. R. & Lloyd, K. O. (1980). Sporothrix schenckii and related species of Ceratocystis. Microbiol Rev 44, 683-721.
148. Travassos, L. R., de Sousa, W., Mendonça-Previato, L. & Lloyd, K. O. (1977). Location and biochemical nature of surface components reacting with concanavalin A in different cell types of Sporothrix schenckii. Exp Mycol 1, 293-305.
149. Trotter, J. R., Sriaroon, P., Berman, D., Petrovic, A. & Leiding, J. W. (2014). Sporothrix schenckii lymphadentitis in a male with X-linked chronic granulomatous disease. J Clin Immunol 34, 49-52.
150. Ulfig, K. (1994). [The occurrence of keratinolytic fungi in the polluted environment of the Labedy district in Gliwice]. Rocz Panstw Zakl Hig 45, 337-346 (in Polish).
151. Ulfig, K., Terakowski, M. & Lukasik, W. (1996). A preliminary study on the occurrence of keratinolytic fungi in the street sweepings from Chorzów. Rocz Panstw Zakl Hig 47, 143-149.
152. Valentín-Berríos, S., González-Velázquez, W., Pérez-Sánchez, L., González-Méndez, R. & Rodríguez-Del Valle, N. (2009). Cytosolic phospholipase A2: a member of the signalling pathway of a new G protein a subunit in Sporothrix schenckii. BMC Microbiol 9, 100.
153. Valix, M. & Loon, L. O. (2003). Adaptive tolerance behavior of fungi in heavy metals. Minerals Engng 16, 193-198.
154. Valix, M., Tang, J. Y. & Malik, R. (2001). Heavy metal tolerance of fungi. Minerals Engng 14, 499-505.
155. Valle-Aviles, L., Valentin-Berrios, S., Gonzalez-Mendez, R. R. & Rodriguez-Del Valle, N. (2007). Functional, genetic and bioinformatic characterization of a calcium/calmodulin kinase gene in Sporothrix schenckii. BMC Microbiol 7, 107.
156. van Duin, D., Casadevall, A. & Nosanchuk, J. D. (2002). Melanization of Cryptococcus neoformans and Histoplasma capsulatum reduces their susceptibilities to amphotericin B and caspofungin. Antimicrob Agents Chemother 46, 3394-3400.
157. Verstrepen, K. J. & Klis, F. M. (2006). Flocculation, adhesion and biofilm formation in yeasts. Mol Microbiol 60, 5-15.
158. Verstrepen, K. J., Derdelinckx, G., Verachtert, H. & Delvaux, F. R. (2003). Yeast flocculation: what brewers should know. Appl Microbiol Biotechnol 61, 197-205.
159. Vilela, R., Souza, G. F., Fernandes Cota, G. & Mendoza, L. (2007). [Cutaneous and meningeal sporotrichosis in a HIV patient]. Rev Iberoam Micol 24, 161-163 (in Spanish)
160. Wang, Y. & Casadevall, A. (1994a). Decreased susceptibility of melanized Cryptococcus neoformans to UV light. Appl Environ Microbiol 60, 3864-3866.
161. Wang, Y. & Casadevall, A. (1994b). Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen-and oxygenderived oxidants. Infect Immun 62, 3004-3007.
162. Wang, X. H., Li, R. Y., Cao, C. W., Wang, Y. H., Liu, W., Qiao, J. J. & Li, Y. Z. (2008). Differential mRNA expression of Sporothrix schenckii catalase gene in two growth phases and effect factors. Chin Med J (Engl) 121, 2100-2102.
163. Weete, J. D. (1989). Structure and function of sterols in fungi. Adv Lipid Res 23, 115-167.
164. Werner, A. H. & Werner, B. E. (1994). Sporotrichosis in man and animal. Int J Dermatol 33, 692-700.
165. Wheeler, M. H. & Bell, A. A. (1988). Melanins and their importance in pathogenic fungi. Curr Top Med Mycol, 2, 338-387.
166. Wroblewska, M., Swoboda-Kopec, E., Kawecki, D., Sawicka-Grzelak, A., Stelmach, E. & Luczak, M. (2005). Infection by a dimorphic fungus Sporothrix schenckii in an immunocompromised patient. Infection 33, 289-291.
167. Wu, H., Downs, D., Ghosh, K., Ghosh, A. K., Staib, P., Monod, M. & Tang, J. (2013). Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism. FASEB J 27, 2132-2144.
168. Xu, J., Yang, Q., Qian, X., Samuelsson, J. & Janson, J. C. (2007). Assessment of 4-nitro-1,8-naphthalic anhydride reductase activity in homogenates of bakers’ yeast by reversed-phase high-performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 847, 82-87.
169. Yazdanparast, S. A., Dargahi, H., Shahrokhi, S. & Farahani, R. H. (2013). Isolation and investigation of keratinophilic fungi in the parks of municipality districts of Tehran. Thrita J Med Sci 2, 2-5.
170. Yegneswaran, P. P., Sripathi, H., Bairy, I., Lonikar, V., Rao, R. & Prabhu, S. (2009). Zoonotic sporotrichosis of lymphocutaneous type in a man acquired from a domesticated feline source: report of a first case in southern Karnataka, India. Int J Dermatol 48, 1198-1200.
171. Zafar, S., Aqil, F. & Ahmad, I. (2007). Metal tolerance and biosorption potential of filamentous fungi isolated from metal contaminated agricultural soil. Bioresour Technol 98, 2557-2561.
172. Zecconi, A. & Scali, F. (2013). Staphylococcus aureus virulence factors in evasion from innate immune defenses in human and animal diseases. Immunol Lett 150, 12-22.
173. Zhang, Z., Hou, B., Xin, Y. & Liu, X. (2012). Protein profiling of the dimorphic pathogenic fungus, Sporothrix schenckii. Mycopathologia 173, 1-11.
174. Zhang, Z., Hou, B., Zheng, F., Yu, X. & Liu, X. (2013). Molecular cloning, characterization and differential expression of a Sporothrix schenckii STE20-like protein kinase SsSte20. Int J Mol Med 31, 1343-1348.