Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism

FASEB Journal

Volumn 27, Issue 6, 2013, Pages 2132-2144

  Wu, Hao ^a   Downs, Deborah ^a   Ghosh, Koena ^b   Ghosh, Arun K ^b   Staib, Peter ^c   Monod, Michel ^d   Tang, Jordan ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b PURDUE UNIVERSITY   (United States)

^c HANS KNÖLL INSTITUTE   (Germany)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Infectious diseases; Integrins; Lysosome membrane; Virulence factors

Indexed keywords

ACRIDINE ORANGE; ASPARTIC PROTEINASE; ASPARTIC PROTEINASE 4; ASPARTIC PROTEINASE 5; ASPARTIC PROTEINASE 6; CASPASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOSOL; ENDOSOME; ENZYME ACTIVATION; ENZYME RELEASE; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTERNALIZATION; KERATINOCYTE; LYSOSOME; MEMBRANE PERMEABILITY; PRIORITY JOURNAL;

INFECTIOUS DISEASES; INTEGRINS; LYSOSOME MEMBRANE; VIRULENCE FACTORS;

AMINO ACID SEQUENCE; APOPTOSIS; ASPARTIC ACID ENDOPEPTIDASES; CANDIDA ALBICANS; CANDIDIASIS; CELL LINE; EPITHELIAL CELLS; FUNGAL PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTEGRINS; LYSOSOMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; VIRULENCE;

CANDIDA ALBICANS; EQUIDAE;

EID: 84878749300     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-214353     Document Type: Article

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