Characterization of virulence profile, protein secretion and immunogenicity of different Sporothrix schenckii sensu stricto isolates compared with S. globosa and S. brasiliensis species

Virulence

Volumn 4, Issue 3, 2013, Pages 241-249

  Fernandes, Geisa Ferreira ^a   dos Santos, Priscila Oliveira ^a   Rodrigues, Anderson Messias ^a   Sasaki, Alexandre Augusto ^a   Burger, Eva ^b   de Camargo, Zoilo Pires ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF ALFENAS   (Brazil)

Author keywords

Antigens; Immunogenicity; Protein secretion; Sporothrix schenckii complex; Sporotrichosis; Virulence; Western blotting

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; FUNGAL VIRULENCE; GENOTYPE; HUMORAL IMMUNITY; IMMUNOBLOTTING; IMMUNOGENICITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN SECRETION; SPOROTHRIX; SPOROTHRIX BRASILIENSIS; SPOROTHRIX GLOBOSA; SPOROTHRIX SCHENCKII; SPOROTRICHOSIS; UNINDEXED SEQUENCE; WESTERN BLOTTING;

EID: 84875939879     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: 10.4161/viru.23112     Document Type: Article

References (56)

1. De Hoog GS. The genera Blastobotrys, Sporothrix, Calcarisporium and Calcarisporiella gen. nov. Stud Mycol 1974; 7:1-84.
2. Arrillaga-Moncrieff I, Capilla J, Mayayo E, Marimon R, Mariné M, Gené J, et al. Different virulence levels of the species of Sporothrix in a murine model. Clin Microbiol Infect 2009; 15:651-5; PMID:19624508; http://dx.doi.org/10.1111/j.1469-0691.2009.02824.x
3. Arrillaga-Moncrieff I, Capilla J, Fernández AM, Fariñas F, Mayayo E. Diferencias en la patogenicidad del complejo de especies Sporothrix en un modelo animal. Patologia 2010; 48:82-7.
4. Rodrigues AM, de Hoog S, de Camargo ZP. Emergence of pathogenicity in the Sporothrix schenckii complex. Med Mycol 2012, In press; PMID:22989196; http:// dx.doi.org/10.3109/13693786.2012.719648
5. Schenck BR. On refractory subcutaneous abscesses caused by a fungus possibly related to sporothrichia. Bull Johns Hopkins Hosp 1898; 9:286-90.
6. Hektoen L, Perkins CF. Refractory subcutaneous abscesses caused by Sporothrix schenckii. A new pathogenic fungus. J Exp Med 1900; 5:77-89; PMID:19866937; http://dx.doi.org/10.1084/ jem.5.1.77
7. Mesa-Arango AC, Del Rocío Reyes-Montes M, Pérez-Mejía A, Navarro-Barranco H, Souza V, Zúñiga G, et al. Phenotyping and genotyping of Sporothrix schenckii isolates according to geographic origin and clinical form of Sporotrichosis. J Clin Microbiol 2002; 40:3004-11; PMID:12149366; http://dx.doi.org/10.1128/ JCM.40.8.3004-3011.2002
8. Neyra E, Fonteyne PA, Swinne D, Fauche F, Bustamante B, Nolard N. Epidemiology of human sporotrichosis investigated by amplified fragment length polymorphism. J Clin Microbiol 2005; 43:1348-52; PMID:15750106; http://dx.doi.org/10.1128/ JCM.43.3.1348-1352.2005
9. Fernandes GF, Santos PO, Amaral CC, Sasaki AA, Martinez-Godoy P, Camargo ZP. Characteristics of 151 Brazilian Sporothrix schenckii isolates from 5 different geographic regions of Brazil: a forgotten and re-emergent pathogen. Open Mycol J 2009; 3:48-58; http://dx.doi.org/10.2174/1874437000903010048
10. Marimon R, Gené J, Cano J, Trilles L, Dos Santos Lazéra M, Guarro J. Molecular phylogeny of Sporothrix schenckii. J Clin Microbiol 2006; 44:3251-6; PMID:16954256; http://dx.doi.org/10.1128/ JCM.00081-06
11. Marimon R, Cano J, Gené J, Sutton DA, Kawasaki M, Guarro J. Sporothrix brasiliensis, S. globosa, and S. mexicana, three new Sporothrix species of clinical interest. J Clin Microbiol 2007; 45:3198-206; PMID:17687013; http://dx.doi.org/10.1128/JCM.00808-07
12. Marimon R, Gené J, Cano J, Guarro J. Sporothrix luriei: a rare fungus from clinical origin. Med Mycol 2008; 46:621-5; PMID:19180753; http://dx.doi. org/10.1080/13693780801992837
13. Romeo O, Scordino F, Criseo G. New insight into molecular phylogeny and epidemiology of Sporothrix schenckii species complex based on calmodulin-encoding gene analysis of Italian isolates. Mycopathologia 2011; 172:179-86; PMID:21461774; http://dx.doi. org/10.1007/s11046-011-9420-z
14. Kwon-Chung K, Bennett J. Chapter 26-Sporotrichosis. In: Kwon-Chung K, Bennett J, eds. Medical Mycology. 1st ed. Philadelphia: Lea & Febiger, 1992: 707-29.
15. Morris-Jones R. Sporotrichosis. Clin Exp Dermatol 2002; 27:427-31; PMID:12372075; http://dx.doi. org/10.1046/j.1365-2230.2002.01087.x
16. Schubach TM, Schubach A, Okamoto T, Barros MB, Figueiredo FB, Cuzzi T, et al. Evaluation of an epidemic of sporotrichosis in cats: 347 cases (1998-2001). J Am Vet Med Assoc 2004; 224:1623-9; PMID:15154732; http://dx.doi.org/10.2460/javma.2004.224.1623
17. Schubach A, Schubach TM, Barros MB, Wanke B. Cat-transmitted sporotrichosis, Rio de Janeiro, Brazil. Emerg Infect Dis 2005; 11:1952-4; PMID:16485488; http://dx.doi.org/10.3201/eid1112.040891
18. Barros MBL, Schubach TP, Coll JO, Gremião ID, Wanke B, Schubach A. [Sporotrichosis: development and challenges of an epidemic]. Rev Panam Salud Publica 2010; 27:455-60; PMID:20721446.
19. Falqueto A, Bravim Maifrede S, Araujo Ribeiro M. Unusual clinical presentation of sporotrichosis in three members of one family. Int J Dermatol 2012; 51:434-8; PMID:22435433; http://dx.doi.org/10.1111/j.1365-4632.2011.5085.x
20. Lopes-Bezerra LM, Schubach A, Costa RO. Sporothrix schenckii and sporotrichosis. An Acad Bras Cienc 2006; 78:293-308; PMID:16710567; http://dx.doi. org/10.1590/S0001-37652006000200009
21. Shaw JC, Levinson W, Montanaro A. Sporotrichosis in the acquired immunodeficiency syndrome. J Am Acad Dermatol 1989; 21:1145-7; PMID:2808849; http:// dx.doi.org/10.1016/S0190-9622(89)70318-2
22. Donabedian H, O'Donnell E, Olszewski C, MacArthur RD, Budd N. Disseminated cutaneous and meningeal sporotrichosis in an AIDS patient. Diagn Microbiol Infect Dis 1994; 18:111-5; PMID:8062528; http:// dx.doi.org/10.1016/0732-8893(94)90075-2
23. Bunce PE, Yang L, Chun S, Zhang SX, Trinkaus MA, Matukas LM. Disseminated sporotrichosis in a patient with hairy cell leukemia treated with amphotericin B and posaconazole. Med Mycol 2012; 50:197-201; PMID:21612561; http://dx.doi.org/10.3109/1369378 6.2011.584074
24. Freitas DF, de Siqueira Hoagland B, do Valle AC, Fraga BB, de Barros MB, de Oliveira Schubach A, et al. Sporotrichosis in HIV-infected patients: report of 21 cases of endemic sporotrichosis in Rio de Janeiro, Brazil. Med Mycol 2012; 50:170-8; PMID:21859385; http://dx.doi.org/10.3109/13693786.2011.596288
25. Silva-Vergara ML, Maneira FR, De Oliveira RM, Santos CT, Etchebehere RM, Adad SJ. Multifocal sporotrichosis with meningeal involvement in a patient with AIDS. Med Mycol 2005; 43:187-90; PMID:15832562; http://dx.doi.org/10.1080/13693780500035904
26. Silva-Vergara ML, de Camargo ZP, Silva PF, Abdalla MR, Sgarbieri RN, Rodrigues AM, et al. Disseminated Sporothrix brasiliensis infection with endocardial and ocular involvement in an HIV-infected patient. Am J Trop Med Hyg 2012; 86:477-80; PMID:22403321; http://dx.doi.org/10.4269/ajtmh.2012.11-0441
27. Carlos IZ, Sgarbi DB, Angluster J, Alviano CS, Silva CL. Detection of cellular immunity with the soluble antigen of the fungus Sporothrix schenckii in the systemic form of the disease. Mycopathologia 1992; 117:139-44; PMID:1640975; http://dx.doi. org/10.1007/BF00442774
28. Carlos IZ, Zini MM, Sgarbi DB, Angluster J, Alviano CS, Silva CL. Disturbances in the production of interleukin-1 and tumor necrosis factor in disseminated murine sporotrichosis. Mycopathologia 1994; 127:189-94; PMID:7808513; http://dx.doi. org/10.1007/BF01102920
29. Carlos IZ, Sgarbi DB, Placeres MC. Host organism defense by a peptide-polysaccharide extracted from the fungus Sporothrix schenckii. Mycopathologia 1998; 144:9-14; PMID:10422268; http://dx.doi. org/10.1023/A:1006964516334
30. Maia DC, Sassá MF, Placeres MC, Carlos IZ. Influence of Th1/Th2 cytokines and nitric oxide in murine systemic infection induced by Sporothrix schenckii. Mycopathologia 2006; 161:11-9; PMID:16389479; http://dx.doi.org/10.1007/s11046-005-0142-y
31. Dixon DM, Salkin IF, Duncan RA, Hurd NJ, Haines JH, Kemna ME, et al. Isolation and characterization of Sporothrix schenckii from clinical and environmental sources associated with the largest U.S. epidemic of sporotrichosis. J Clin Microbiol 1991; 29:1106-13; PMID:1864926.
32. Tachibana T, Matsuyama T, Mitsuyama M. Characteristic infectivity of Sporothrix schenckii to mice depending on routes of infection and inherent fungal pathogenicity. Med Mycol 1998; 36:21-7; PMID:9776808; http:// dx.doi.org/10.1080/02681219880000041
33. Kong X, Xiao T, Lin J, Wang Y, Chen HD. Relationships among genotypes, virulence and clinical forms of Sporothrix schenckii infection. Clin Microbiol Infect 2006; 12:1077-81; PMID:17002606; http:// dx.doi.org/10.1111/j.1469-0691.2006.01519.x
34. Brito MM, Conceição-Silva F, Morgado FN, Raibolt PS, Schubach A, Schubach TP, et al. Comparison of virulence of different Sporothrix schenckii clinical isolates using experimental murine model. Med Mycol 2007; 45:721-9; PMID:17885952; http://dx.doi. org/10.1080/13693780701625131
35. Fernandes KS, Mathews HL, Lopes Bezerra LM. Differences in virulence of Sporothrix schenckii conidia related to culture conditions and cell-wall components. J Med Microbiol 1999; 48:195-203; PMID:9989648; http://dx.doi.org/10.1099/00222615-48-2-195
36. de Beer ZW, Harrington TC, Vismer HF, Wingfield BD, Wingfield MJ. Phylogeny of the Ophiostoma stenoceras-Sporothrix schenckii complex. Mycologia 2003; 95:434-41; PMID:21156632; http://dx.doi. org/10.2307/3761885
37. Kawasaki M, Watanabe S, Ishizaki H. 2003, http:// www.ncbi.nlm.nih.gov/nuccore
38. Watanabe S, Kawasaki M, Mochiduki T, Ishizaki H. 2004, http://www.ncbi.nlm.nih.gov/nuccore
39. Aghayeva DN, Wingfield MJ, Kirisits T, Wingfield BD. Ophiostoma dentifundum sp. nov. from oak in Europe, characterized using molecular phylogenetic data and morphology. Mycol Res 2005; 109:1127-36; PMID:16279407; http://dx.doi.org/10.1017/ S0953756205003710
40. Gujjari P, Suh SO, Zhou J. 2008; http://www.ncbi. nlm.nih.gov/nuccore
41. de Meyer EM, de Beer ZW, Summerbell RC, Moharram AM, de Hoog GS, Vismer HF, et al. Taxonomy and phylogeny of new wood-and soil-inhabiting Sporothrix species in the Ophiostoma stenoceras-Sporothrix schenckii complex. Mycologia 2008; 100:647-61; PMID:18833758; http://dx.doi.org/10.3852/07-157R
42. Madrid H, Gené J, Cano J, Silvera C, Guarro J. Sporothrix brunneoviolacea and Sporothrix dimorphospora, two new members of the Ophiostoma stenoceras-Sporothrix schenckii complex. Mycologia 2010; 102:1193-203; PMID:20943519; http://dx.doi.org/10.3852/09-320
43. Fernandes GF, Do Amaral CC, Sasaki AA, Godoy PM, De Camargo ZP. Heterogeneity of proteins expressed by Brazilian Sporothrix schenckii isolates. Med Mycol 2009; 47:855-61; PMID:19184772; http://dx.doi. org/10.3109/13693780802713216
44. Mendoza M, Díaz AM, Hung MB, Zambrano EA, Díaz E, De Albornoz MC. Production of culture filtrates of Sporothrix schenckii in diverse culture media. Med Mycol 2002; 40:447-54; PMID:12462523.
45. O'Donnell K. Molecular phylogeny of the Nectria haematococca-Fusarium solani species complex. Mycologia 2000; 92:919-38; http://dx.doi.org/10.2307/3761588
46. White TJ, Bruns T, Lee S, Taylor J. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. In: Innis MA, Gelfand DH, Sninsky JJ, White TJ, eds. PCR Protocols-a Guide to Methods and Application. San Diego: Academic Press, 1990:315-22.
47. Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 1994; 22:4673-80; PMID:7984417; http://dx.doi.org/10.1093/nar/22.22.4673
48. Hall TA. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp Ser 1999; 41:95-8.
49. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011; 28:2731-9; PMID:21546353; http:// dx.doi.org/10.1093/molbev/msr121
50. Kimura M. A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 1980; 16:111-20; PMID:7463489; http://dx.doi. org/10.1007/BF01731581
51. Tamura K. Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C content biase. Mol Biol Evol 1992; 4:678-87.
52. Felsenstein J. Confidence limits on phylogenies: An approach using the bootstrap. Evolution 1985; 39:783-91; http://dx.doi.org/10.2307/2408678
53. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-54; PMID:942051; http:// dx.doi.org/10.1016/0003-2697(76)90527-3
54. Zar JH. Biostatistical analysis, 2nded. New Jersey: Prentice-Hall, Englewood Cliffs 1984.
55. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-5; PMID:5432063; http://dx.doi. org/10.1038/227680a0
56. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979; 76:4350-4; PMID:388439; http://dx.doi.org/10.1073/pnas.76.9.4350