Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males

Journal of Cell Science

Volumn 128, Issue 12, 2015, Pages 2314-2327

  Modzelewski, Andrew J ^a   Hilz, Stephanie ^a   Crate, Elizabeth A ^a   Schweidenback, Caterina T H ^a   Fogarty, Elizabeth A ^a   Grenier, Jennifer K ^a   Freire, Raimundo ^b   Cohen, Paula E ^a   Grimson, Andrew ^a  

^a Cornell University ^*  (United States)

^b HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

Author keywords

Dgcr8; Dicer; Dicer1; Germ line; Meiosis; MicroRNA; Sex body; Sex chromosomes; Telomere

Indexed keywords

ATM PROTEIN; CYCLIN DEPENDENT KINASE 2; DGCR8 PROTEIN; DICER; DNA DAMAGE CHECKPOINT 1 PROTEIN; HISTONE H2AX; MESSENGER RNA; MICRORNA; MICRORNA 16; MICRORNA 18; PROTEIN; RNF8 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTOME; UNCLASSIFIED DRUG; DEAD BOX PROTEIN; DGCR8 PROTEIN, MOUSE; DICER1 PROTEIN, MOUSE; RIBONUCLEASE III; RNA BINDING PROTEIN;

3' UNTRANSLATED REGION; ADULT; ANIMAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOSOME; BODY SIZE; CHROMOSOMAL LOCALIZATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE CHECKPOINT; DNA END JOINING REPAIR; DOWN REGULATION; GENOMIC INSTABILITY; HISTOLOGY; IMMUNOFLUORESCENCE TEST; MALE; MALE STERILITY; MEIOSIS; MOUSE; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEX CHROMOSOME; SPERMATOCYTE; SPERMATOGENESIS; SYNAPSE; SYNAPTONEMAL COMPLEX; TELOMERE; TELOMERE HOMEOSTASIS; TESTIS WEIGHT; TUNEL ASSAY; UPREGULATION; C57BL MOUSE; CELL CULTURE; CYTOLOGY; FEMALE; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MAMMALIA; MUS;

ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELLS, CULTURED; DEAD-BOX RNA HELICASES; FEMALE; MALE; MEIOSIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASE III; RNA, MESSENGER; RNA-BINDING PROTEINS; SEX CHROMOSOMES; SPERMATOCYTES;

EID: 84932143654     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.167148     Document Type: Article

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