Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Zimmermann, Céline ^a   Romero, Yannick ^a   Warnefors, Maria ^b   Bilican, Adem ^b   Borel, Christelle ^a   Smith, Lee B ^c   Kotaja, Noora ^d   Kaessmann, Henrik ^b   Nef, Serge ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MICRORNA; SMALL INTERFERING RNA; DGCR8 PROTEIN, MOUSE; RIBONUCLEASE III; RNA BINDING PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AZOOSPERMIA; CONTROLLED STUDY; DGCR8 GENE; DICER1 GENE; GENE; GENE EXPRESSION; GENE INACTIVATION; HAPLOIDY; MALE; MALE FERTILITY; MEIOSIS; MOUSE; NONHUMAN; OLIGOSPERMIA; PHENOTYPE; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN TARGETING; RNA SEQUENCE; SPERMATOCYTE; SPERMATOGENESIS; ANIMAL; FERTILITY; GENETICS; KNOCKOUT MOUSE; MALE INFERTILITY; METABOLISM; SPERMATOZOON; TESTIS;

MAMMALIA;

ANIMALS; FERTILITY; INFERTILITY, MALE; MALE; MICE; MICE, KNOCKOUT; RIBONUCLEASE III; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

EID: 84907190331     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107023     Document Type: Article

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