메뉴 건너뛰기




Volumn 195, Issue 1, 2015, Pages 289-297

Bipartite nuclear localization signal controls nuclear import and DNA-binding activity of IFN regulatory factor 3

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERFERON REGULATORY FACTOR 3; DNA; IRF3 PROTEIN, MOUSE; NUCLEAR LOCALIZATION SIGNAL; PROTEIN BINDING;

EID: 84932134515     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500232     Document Type: Article
Times cited : (42)

References (40)
  • 1
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O., and S. Akira. 2010. Pattern recognition receptors and inflammation. Cell 140: 805-820.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 2
    • 84893075305 scopus 로고    scopus 로고
    • Regulation of type i interferon responses
    • Ivashkiv, L. B., and L. T. Donlin. 2014. Regulation of type I interferon responses. Nat. Rev. Immunol. 14: 36-49.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 36-49
    • Ivashkiv, L.B.1    Donlin, L.T.2
  • 3
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai, T., and S. Akira. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34: 637-650.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 4
    • 58049217490 scopus 로고    scopus 로고
    • RNA recognition and signal transduction by RIG-I-like receptors
    • Yoneyama, M., and T. Fujita. 2009. RNA recognition and signal transduction by RIG-I-like receptors. Immunol. Rev. 227: 54-65.
    • (2009) Immunol. Rev. , vol.227 , pp. 54-65
    • Yoneyama, M.1    Fujita, T.2
  • 5
    • 0033842515 scopus 로고    scopus 로고
    • Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7
    • Lin, R., P. Génin, Y. Mamane, and J. Hiscott. 2000. Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7. Mol. Cell. Biol. 20: 6342-6353.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6342-6353
    • Lin, R.1    Génin, P.2    Mamane, Y.3    Hiscott, J.4
  • 6
    • 0024424123 scopus 로고
    • Two different virus-inducible elements are required for human beta-interferon gene regulation
    • Fan, C. M., and T. Maniatis. 1989. Two different virus-inducible elements are required for human beta-interferon gene regulation. EMBO J. 8: 101-110.
    • (1989) EMBO J. , vol.8 , pp. 101-110
    • Fan, C.M.1    Maniatis, T.2
  • 7
    • 0024516201 scopus 로고
    • The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction
    • Lenardo, M. J., C. M. Fan, T. Maniatis, and D. Baltimore. 1989. The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 57: 287-294.
    • (1989) Cell , vol.57 , pp. 287-294
    • Lenardo, M.J.1    Fan, C.M.2    Maniatis, T.3    Baltimore, D.4
  • 8
    • 0024443096 scopus 로고
    • Double-stranded RNA activates binding of NF-kappa B to an inducible element in the human beta-interferon promoter
    • Visvanathan, K. V., and S. Goodbourn. 1989. Double-stranded RNA activates binding of NF-kappa B to an inducible element in the human beta-interferon promoter. EMBO J. 8: 1129-1138.
    • (1989) EMBO J. , vol.8 , pp. 1129-1138
    • Visvanathan, K.V.1    Goodbourn, S.2
  • 9
    • 0029565392 scopus 로고
    • A novel PRD i and TG binding activity involved in virus-induced transcription of IFN-A genes
    • Génin, P., J. Braganc?a, N. Darracq, J. Doly, and A. Civas. 1995. A novel PRD I and TG binding activity involved in virus-induced transcription of IFN-A genes. Nucleic Acids Res. 23: 5055-5063.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 5055-5063
    • Génin, P.1    Braganca, J.2    Darracq, N.3    Doly, J.4    Civas, A.5
  • 10
    • 0024348544 scopus 로고
    • Upstream regulatory elements of murine alpha 4-interferon gene confer inducibility and cell typerestricted expression
    • Raj, N. B., R. Israeli, M. Kellum, and P. M. Pitha. 1989. Upstream regulatory elements of murine alpha 4-interferon gene confer inducibility and cell typerestricted expression. J. Biol. Chem. 264: 11149-11157.
    • (1989) J. Biol. Chem. , vol.264 , pp. 11149-11157
    • Raj, N.B.1    Israeli, R.2    Kellum, M.3    Pitha, P.M.4
  • 11
    • 0022366774 scopus 로고
    • A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus
    • Ryals, J., P. Dierks, H. Ragg, and C. Weissmann. 1985. A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus. Cell 41: 497-507.
    • (1985) Cell , vol.41 , pp. 497-507
    • Ryals, J.1    Dierks, P.2    Ragg, H.3    Weissmann, C.4
  • 12
    • 0033568642 scopus 로고    scopus 로고
    • Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences
    • Fujii, Y., T. Shimizu, M. Kusumoto, Y. Kyogoku, T. Taniguchi, and T. Hakoshima. 1999. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. EMBO J. 18: 5028-5041.
    • (1999) EMBO J. , vol.18 , pp. 5028-5041
    • Fujii, Y.1    Shimizu, T.2    Kusumoto, M.3    Kyogoku, Y.4    Taniguchi, T.5    Hakoshima, T.6
  • 13
    • 10044239268 scopus 로고    scopus 로고
    • Crystal structure of ATF-2/ c-Jun and IRF-3 bound to the interferon-beta enhancer
    • Panne, D., T. Maniatis, and S. C. Harrison. 2004. Crystal structure of ATF-2/ c-Jun and IRF-3 bound to the interferon-beta enhancer. EMBO J. 23: 4384-4393.
    • (2004) EMBO J. , vol.23 , pp. 4384-4393
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 14
    • 0032015647 scopus 로고    scopus 로고
    • Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo
    • Wathelet, M. G., C. H. Lin, B. S. Parekh, L. V. Ronco, P. M. Howley, and T. Maniatis. 1998. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol. Cell 1: 507-518.
    • (1998) Mol. Cell , vol.1 , pp. 507-518
    • Wathelet, M.G.1    Lin, C.H.2    Parekh, B.S.3    Ronco, L.V.4    Howley, P.M.5    Maniatis, T.6
  • 15
    • 0035061538 scopus 로고    scopus 로고
    • IRF family of transcription factors as regulators of host defense
    • Taniguchi, T., K. Ogasawara, A. Takaoka, and N. Tanaka. 2001. IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19: 623-655.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 623-655
    • Taniguchi, T.1    Ogasawara, K.2    Takaoka, A.3    Tanaka, N.4
  • 16
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell, J. E., Jr., I. M. Kerr, and G. R. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 17
    • 0027250364 scopus 로고
    • Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system
    • Tanaka, N., T. Kawakami, and T. Taniguchi. 1993. Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system. Mol. Cell. Biol. 13: 4531-4538.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4531-4538
    • Tanaka, N.1    Kawakami, T.2    Taniguchi, T.3
  • 18
    • 33748475531 scopus 로고    scopus 로고
    • Type i interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
    • Honda, K., A. Takaoka, and T. Taniguchi. 2006. Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 25: 349-360.
    • (2006) Immunity , vol.25 , pp. 349-360
    • Honda, K.1    Takaoka, A.2    Taniguchi, T.3
  • 19
    • 0023788435 scopus 로고
    • Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements
    • Miyamoto, M., T. Fujita, Y. Kimura, M. Maruyama, H. Harada, Y. Sudo, T. Miyata, and T. Taniguchi. 1988. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell 54: 903-913.
    • (1988) Cell , vol.54 , pp. 903-913
    • Miyamoto, M.1    Fujita, T.2    Kimura, Y.3    Maruyama, M.4    Harada, H.5    Sudo, Y.6    Miyata, T.7    Taniguchi, T.8
  • 23
    • 0031893220 scopus 로고    scopus 로고
    • Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
    • Lin, R., C. Heylbroeck, P. M. Pitha, and J. Hiscott. 1998. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol. Cell. Biol. 18: 2986-2996.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2986-2996
    • Lin, R.1    Heylbroeck, C.2    Pitha, P.M.3    Hiscott, J.4
  • 24
    • 0036710523 scopus 로고    scopus 로고
    • Multiple signaling pathways leading to the activation of interferon regulatory factor 3
    • Servant, M. J., N. Grandvaux, and J. Hiscott. 2002. Multiple signaling pathways leading to the activation of interferon regulatory factor 3. Biochem. Pharmacol. 64: 985-992.
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 985-992
    • Servant, M.J.1    Grandvaux, N.2    Hiscott, J.3
  • 25
    • 0032481352 scopus 로고    scopus 로고
    • Direct triggering of the type i interferon system by virus infection: Activation of a transcription factor complex containing IRF-3 and CBP/p300
    • Yoneyama, M., W. Suhara, Y. Fukuhara, M. Fukuda, E. Nishida, and T. Fujita. 1998. Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J. 17: 1087-1095.
    • (1998) EMBO J. , vol.17 , pp. 1087-1095
    • Yoneyama, M.1    Suhara, W.2    Fukuhara, Y.3    Fukuda, M.4    Nishida, E.5    Fujita, T.6
  • 26
    • 33847176295 scopus 로고    scopus 로고
    • Molecular mechanism of the nuclear protein import cycle
    • Stewart, M. 2007. Molecular mechanism of the nuclear protein import cycle. Nat. Rev. Mol. Cell Biol. 8: 195-208.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 195-208
    • Stewart, M.1
  • 27
    • 14544299215 scopus 로고    scopus 로고
    • Mechanisms of receptor-mediated nuclear import and nuclear export
    • Pemberton, L. F., and B. M. Paschal. 2005. Mechanisms of receptor-mediated nuclear import and nuclear export. Traffic 6: 187-198.
    • (2005) Traffic , vol.6 , pp. 187-198
    • Pemberton, L.F.1    Paschal, B.M.2
  • 28
    • 0034653375 scopus 로고    scopus 로고
    • Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha
    • Conti, E., and J. Kuriyan. 2000. Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Structure 8: 329-338.
    • (2000) Structure , vol.8 , pp. 329-338
    • Conti, E.1    Kuriyan, J.2
  • 29
    • 0026078249 scopus 로고
    • Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
    • Robbins, J., S. M. Dilworth, R. A. Laskey, and C. Dingwall. 1991. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 64: 615-623.
    • (1991) Cell , vol.64 , pp. 615-623
    • Robbins, J.1    Dilworth, S.M.2    Laskey, R.A.3    Dingwall, C.4
  • 30
    • 0034111332 scopus 로고    scopus 로고
    • Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1
    • Kumar, K. P., K. M. McBride, B. K. Weaver, C. Dingwall, and N. C. Reich. 2000. Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1. Mol. Cell. Biol. 20: 4159-4168.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4159-4168
    • Kumar, K.P.1    McBride, K.M.2    Weaver, B.K.3    Dingwall, C.4    Reich, N.C.5
  • 31
    • 34447499052 scopus 로고    scopus 로고
    • Triggering the innate antiviral response through IRF-3 activation
    • Hiscott, J. 2007. Triggering the innate antiviral response through IRF-3 activation. J. Biol. Chem. 282: 15325-15329.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15325-15329
    • Hiscott, J.1
  • 32
    • 34250017968 scopus 로고    scopus 로고
    • An atomic model of the interferon-beta enhanceosome
    • Panne, D., T. Maniatis, and S. C. Harrison. 2007. An atomic model of the interferon-beta enhanceosome. Cell 129: 1111-1123.
    • (2007) Cell , vol.129 , pp. 1111-1123
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 34
    • 0034691151 scopus 로고    scopus 로고
    • Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors
    • Lau, J. F., J. P. Parisien, and C. M. Horvath. 2000. Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors. Proc. Natl. Acad. Sci. USA 97: 7278-7283.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7278-7283
    • Lau, J.F.1    Parisien, J.P.2    Horvath, C.M.3
  • 35
    • 0036311933 scopus 로고    scopus 로고
    • Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes
    • Barnes, B. J., M. J. Kellum, A. E. Field, and P. M. Pitha. 2002. Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes. Mol. Cell. Biol. 22: 5721-5740.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5721-5740
    • Barnes, B.J.1    Kellum, M.J.2    Field, A.E.3    Pitha, P.M.4
  • 36
    • 0025949412 scopus 로고
    • Nuclear targeting sequences-a consensus?
    • Dingwall, C., and R. A. Laskey. 1991. Nuclear targeting sequences-a consensus? Trends Biochem. Sci. 16: 478-481.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 478-481
    • Dingwall, C.1    Laskey, R.A.2
  • 37
    • 77949498332 scopus 로고    scopus 로고
    • Expanding the definition of the classical bipartite nuclear localization signal
    • Lange, A., L. M. McLane, R. E. Mills, S. E. Devine, and A. H. Corbett. 2010. Expanding the definition of the classical bipartite nuclear localization signal. Traffic 11: 311-323.
    • (2010) Traffic , vol.11 , pp. 311-323
    • Lange, A.1    McLane, L.M.2    Mills, R.E.3    Devine, S.E.4    Corbett, A.H.5
  • 38
    • 0029922169 scopus 로고    scopus 로고
    • Molecular dissection of the nuclear pore complex
    • Panté, N., and U. Aebi. 1996. Molecular dissection of the nuclear pore complex. Crit. Rev. Biochem. Mol. Biol. 31: 153-199.
    • (1996) Crit. Rev. Biochem. Mol. Biol. , vol.31 , pp. 153-199
    • Panté, N.1    Aebi, U.2
  • 39
  • 40
    • 0032915860 scopus 로고    scopus 로고
    • Structural and functional analysis of interferon regulatory factor 3: Localization of the transactivation and autoinhibitory domains
    • Lin, R., Y. Mamane, and J. Hiscott. 1999. Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains. Mol. Cell. Biol. 19: 2465-2474.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2465-2474
    • Lin, R.1    Mamane, Y.2    Hiscott, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.