Role of CtBP2 in the Apoptosis of Retinal Ganglion Cells

Cellular and Molecular Neurobiology

Volumn 35, Issue 5, 2015, Pages 633-640

  Wang, Wenwen ^a,b   Zhang, Guowei ^b   Gu, Hui ^a   Liu, Ye ^a   Lao, Jifeng ^a   Li, Kuifang ^a   Guan, Huaijin ^b  

^a Department of Pathology of Traditional Chinese Medicine Hospital ^*  (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Apoptosis; CtBP2; Glaucoma; RGC

Indexed keywords

BINDING PROTEIN; C TERMINAL-BINDING PROTEIN 2; GLUTAMIC ACID; UNCLASSIFIED DRUG; CTBP2 PROTEIN, MOUSE; DNA BINDING PROTEIN; PHOSPHOPROTEIN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; DBA 2 MOUSE; EXPERIMENTAL GLAUCOMA; IMMUNOREACTIVITY; INTRAOCULAR PRESSURE; MALE; MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA GANGLION CELL; SPATIAL ANALYSIS; TEMPORAL ANALYSIS; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DBA MOUSE; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; METABOLISM;

AGING; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; DNA-BINDING PROTEINS; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; MALE; MICE, INBRED C57BL; MICE, INBRED DBA; PHOSPHOPROTEINS; RETINAL GANGLION CELLS;

EID: 84931956723     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-015-0158-x     Document Type: Article

References (44)

1. Ayoub GS, Copenhagen DR (1991) Application of a fluorometric method to measure glutamate release from single retinal photoreceptors. J Neurosci Methods 37:7–14
2. Bouhenni RA, Dunmire J, Sewell A, Edward DP (2012) Animal models of glaucoma. J Biomed Biotechnol 2012:692609
3. Buckingham BP, Inman DM, Lambert W, Oglesby E, Calkins DJ, Steele MR, Vetter ML, Marsh-Armstrong N, Horner PJ (2008) Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma. J Neurosci 28:2735–2744
4. Burroughs SL, Kaja S, Koulen P (2011) Quantification of deficits in spatial visual function of mouse models for glaucoma. Invest Ophthalmol Vis Sci 52:3654–3659
5. Chinnadurai G (2007) Transcriptional regulation by C-terminal binding proteins. Int J Biochem Cell Biol 39:1593–1607
6. Chinnadurai G (2009) The transcriptional corepressor CtBP: a foe of multiple tumor suppressors. Cancer Res 69:731–734
7. Danias J, Lee KC, Zamora MF, Chen B, Shen F, Filippopoulos T, Su Y, Goldblum D, Podos SM, Mittag T (2003) Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 mice. Invest Ophthalmol Vis Sci 44(12):5151–5162
8. Dong LD, Chen J, Li F, Gao F, Wu J, Miao Y, Wang Z (2013) Enhanced expression of NR2B subunits of NMDA receptors in the inherited glaucomatous DBA/2J mouse retina. Neural Plast 2013:670254
9. Elkholi R, Floros KV, Chipuk JE (2011) The role of BH3-only proteins in tumor cell development, signaling, and treatment. Genes Cancer 2:523–537
10. Ghosh AP, Walls KC, Klocke BJ, Toms R, Strasser A, Roth KA (2009) The proapoptotic BH3-only, Bcl-2 family member, Puma is critical for acute ethanol-induced neuronal apoptosis. J Neuropathol Exp Neurol 68:747–756
11. Guo L, Salt TE, Maass A, Luong V, Moss SE, Fitzke FW, Cordeiro MF (2006) Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo. Invest Ophthalmol Vis Sci 47:626–633
12. Harder JM, Fernandes KA, Libby RT (2012) The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice. Sci Rep 2:530
13. Hildebrand JD, Soriano P (2002) Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development. Mol Cell Biol 22:5296–5307
14. Hong S, Iizuka Y, Kim CY, Seong GJ (2012) Isolation of primary mouse retinal ganglion cells using immunopanning-magnetic separation. Mol Vis 18:2922–2930
15. Huang W, Dobberfuhl A, Filippopoulos T, Ingelsson M, Fileta JB, Poulin NR, Grosskreutz CL (2005) Transcriptional up-regulation and activation of initiating caspases in experimental glaucoma. Am J Pathol 167:673–681
16. Ji J, Chang P, Pennesi ME, Yang Z, Zhang J, Li D, Wu SM, Gross RL (2005) Effects of elevated intraocular pressure on mouse retinal ganglion cells. Vision Res 45:169–179
17. Kasaai B, Moffatt P, Al-Salmi L, Lauzier D, Lessard L, Hamdy RC (2012) Spatial and temporal localization of WNT signaling proteins in a mouse model of distraction osteogenesis. J Histochem Cytochem 60(3):219–228
18. Kook S, Zhan X, Cleghorn WM, Benovic JL, Gurevich VV, Gurevich EV (2014) Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death. Cell Death Differ 21(1):172–184
19. Kovi RC, Paliwal S, Pande S, Grossman SR (2010) An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosis. Cell Death Differ 17:513–521
20. Kudo W, Lee HP, Smith MA, Zhu X, Matsuyama S, Lee HG (2012) Inhibition of Bax protects neuronal cells from oligomeric Abeta neurotoxicity. Cell Death Dis 3:e309
21. Labi V, Erlacher M, Kiessling S, Villunger A (2006) BH3-only proteins in cell death initiation, malignant disease and anticancer therapy. Cell Death Differ 13:1325–1338
22. Levin LA, Gordon LK (2002) Retinal ganglion cell disorders: types and treatments. Prog Retin Eye Res 21:465–484
23. Libby RT, Anderson MG, Pang IH, Robinson ZH, Savinova OV, Cosma IM, Snow A, Wilson LA, Smith RS, Clark AF, John SW (2005a) Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration. Vis Neurosci 22:637–648
24. Libby RT, Li Y, Savinova OV, Barter J, Smith RS, Nickells RW, John SW (2005b) Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage. PLoS Genet 1:17–26
25. Lotery AJ (2005) Glutamate excitotoxicity in glaucoma: truth or fiction? Eye (Lond) 19:369–370
26. Massey SC, Miller RF (1990) N-methyl-D-aspartate receptors of ganglion cells in rabbit retina. J Neurophysiol 63:16–30
27. McKinnon SJ, Schlamp CL, Nickells RW (2009) Mouse models of retinal ganglion cell death and glaucoma. Exp Eye Res 88:816–824
28. Munemasa Y, Kitaoka Y (2012) Molecular mechanisms of retinal ganglion cell degeneration in glaucoma and future prospects for cell body and axonal protection. Front Cell Neurosci 6:60
29. Nagaraju M, Saleh M, Porciatti V (2007) IOP-dependent retinal ganglion cell dysfunction in glaucomatous DBA/2J mice. Invest Ophthalmol Vis Sci 48:4573–4579
30. Nicholls D, Attwell D (1990) The release and uptake of excitatory amino acids. Trends Pharmacol Sci 11:462–468
31. Olney JW (1982) The toxic effects of glutamate and related compounds in the retina and the brain. Retina 2:341–359
32. Qu J, Wang D, Grosskreutz CL (2010) Mechanisms of retinal ganglion cell injury and defense in glaucoma. Exp Eye Res 91:48–53
33. Quigley HA, Broman AT (2006) The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262–267
34. Reichstein D, Ren L, Filippopoulos T, Mittag T, Danias J (2007) Apoptotic retinal ganglion cell death in the DBA/2 mouse model of glaucoma. Exp Eye Res 84:13–21
35. Resnikoff S, Pascolini D, Etya’ale D, Kocur I, Pararajasegaram R, Pokharel GP, Mariotti SP (2004) Global data on visual impairment in the year 2002. Bull World Health Organ 82:844–851
36. Saleh M, Nagaraju M, Porciatti V (2007) Longitudinal evaluation of retinal ganglion cell function and IOP in the DBA/2J mouse model of glaucoma. Invest Ophthalmol Vis Sci 48:4564–4572
37. Scholz M, Buder T, Seeber S, Adamek E, Becker CM, Lutjen-Drecoll E (2008) Dependency of intraocular pressure elevation and glaucomatous changes in DBA/2J and DBA/2J-Rj mice. Invest Ophthalmol Vis Sci 49:613–621
38. Straza MW, Paliwal S, Kovi RC, Rajeshkumar B, Trenh P, Parker D, Whalen GF, Lyle S, Schiffer CA, Grossman SR (2010) Therapeutic targeting of C-terminal binding protein in human cancer. Cell Cycle 9:3740–3750
39. Thoreson WB, Witkovsky P (1999) Glutamate receptors and circuits in the vertebrate retina. Prog Retin Eye Res 18:765–810
40. Uthaiah RC, Hudspeth AJ (2010) Molecular anatomy of the hair cell’s ribbon synapse. J Neurosci 30:12387–12399
41. Yürekli I, Gökalp O, Kiray M, Gökalp G, Ergüneş K, Salman E, Yürekli BS, Satoğlu IS, Beşir Y, Cakır H, Gürbüz A (2013) Effect of pheniramine maleate on reperfusion injury in brain tissue. Med Sci Monit Basic Res 19:285–290
42. Zhang G, Yan Y, Kang L, Cao Q, Ke K, Wu X, Gao Y, Hang Q, Li C, Zhu L, Yuan Q, Wu Q, Cheng C (2012) Involvement of CtBP2 in LPS-induced microglial activation. J Mol Histol 43:327–334
43. Zhong YS, Leung CK, Pang CP (2007) Glial cells and glaucomatous neuropathy. Chin Med J (Engl) 120:326–335
44. Zou F, Xu J, Fu H, Cao J, Mao H, Gong M, Cui G, Zhang Y, Shi W, Chen J (2013) Different functions of HIPK2 and CtBP2 in traumatic brain injury. J Mol Neurosci 49:395–408