-
1
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle DE, Zindy F, Ashmun RA, Sherr CJ. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995; 83: 993-1000.
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
2
-
-
0037309326
-
Tumor suppression by Ink4a-Arf: Progress and puzzles
-
Lowe SW, Sherr CJ. Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Genet Dev 2003; 13: 77-83.
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 77-83
-
-
Lowe, S.W.1
Sherr, C.J.2
-
3
-
-
0034665749
-
P53-independent functions of the p19(ARF) tumor suppressor
-
Weber JD, Jeffers JR, Rehg JE, Randle DH, Lozano G, Roussel MF et al. p53-independent functions of the p19(ARF) tumor suppressor. Genes Dev 2000; 14: 2358-2365.
-
(2000)
Genes Dev
, vol.14
, pp. 2358-2365
-
-
Weber, J.D.1
Jeffers, J.R.2
Rehg, J.E.3
Randle, D.H.4
Lozano, G.5
Roussel, M.F.6
-
5
-
-
0034745679
-
Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer
-
Burri N, Shaw P, Bouzourene H, Sordat I, Sordat B, Gillet M et al. Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer. Lab Invest 2001; 81: 217-229.
-
(2001)
Lab Invest
, vol.81
, pp. 217-229
-
-
Burri, N.1
Shaw, P.2
Bouzourene, H.3
Sordat, I.4
Sordat, B.5
Gillet, M.6
-
6
-
-
33644758569
-
Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis
-
Paliwal S, Pande S, Kovi RC, Sharpless NE, Bardeesy N, Grossman SR. Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis. Mol Cell Biol 2006; 26: 2360-2372.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2360-2372
-
-
Paliwal, S.1
Pande, S.2
Kovi, R.C.3
Sharpless, N.E.4
Bardeesy, N.5
Grossman, S.R.6
-
7
-
-
0028838348
-
Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation
-
Schaeper U, Boyd JM, Verma S, Uhlmann E, Subramanian T, Chinnadurai G. Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc Natl Acad Sci USA 1995; 92: 10467-10471.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10467-10471
-
-
Schaeper, U.1
Boyd, J.M.2
Verma, S.3
Uhlmann, E.4
Subramanian, T.5
Chinnadurai, G.6
-
8
-
-
0036810314
-
Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase
-
Kumar V, Carlson JE, Ohgi KA, Edwards TA, Rose DW, Escalante CR et al. Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Mol Cell 2002; 10: 857-869.
-
(2002)
Mol Cell
, vol.10
, pp. 857-869
-
-
Kumar, V.1
Carlson, J.E.2
Ohgi, K.A.3
Edwards, T.A.4
Rose, D.W.5
Escalante, C.R.6
-
9
-
-
0345352743
-
C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs
-
Grooteclaes M, Deveraux Q, Hildebrand J, Zhang Q, Goodman RH, Frisch SM. C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. Proc Natl Acad Sci USA 2003; 100: 4568-4573.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4568-4573
-
-
Grooteclaes, M.1
Deveraux, Q.2
Hildebrand, J.3
Zhang, Q.4
Goodman, R.H.5
Frisch, S.M.6
-
10
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22: 8590-8607.
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
11
-
-
0032574761
-
Bax directly induces release of cytochrome c from isolated mitochondria
-
Jurgensmeier JM, Xie Z, Deveraux Q, Ellerby L, Bredesen D, Reed JC. Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci USA 1998; 95: 4997-5002.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4997-5002
-
-
Jurgensmeier, J.M.1
Xie, Z.2
Deveraux, Q.3
Ellerby, L.4
Bredesen, D.5
Reed, J.C.6
-
12
-
-
0037124113
-
BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria
-
Germain M, Mathai JP, Shore GC. BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria. J Biol Chem 2002; 277: 18053-18060.
-
(2002)
J Biol Chem
, vol.277
, pp. 18053-18060
-
-
Germain, M.1
Mathai, J.P.2
Shore, G.C.3
-
13
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998; 94: 481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
14
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999; 286: 1735-1738.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.3
Tarlinton, D.M.4
Kay, T.W.5
Kontgen, F.6
-
15
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and-independent apoptotic pathways
-
Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J et al. Puma is an essential mediator of p53-dependent and-independent apoptotic pathways. Cancer Cell 2003; 4: 321-328.
-
(2003)
Cancer Cell
, vol.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
Yang, C.4
Wang, J.5
Brennan, J.6
-
16
-
-
0036849192
-
Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis
-
Datta SR, Ranger AM, Lin MZ, Sturgill JF, Ma YC, Cowan CW et al. Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis. Dev Cell 2002; 3: 631-643.
-
(2002)
Dev Cell
, vol.3
, pp. 631-643
-
-
Datta, S.R.1
Ranger, A.M.2
Lin, M.Z.3
Sturgill, J.F.4
Ma, Y.C.5
Cowan, C.W.6
-
17
-
-
36349021416
-
Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis
-
Gillissen B, Essmann F, Hemmati PG, Richter A, Richter A, Oztop I et al. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis. J Cell Biol 2007; 179: 701-715.
-
(2007)
J Cell Biol
, vol.179
, pp. 701-715
-
-
Gillissen, B.1
Essmann, F.2
Hemmati, P.G.3
Richter, A.4
Richter, A.5
Oztop, I.6
-
18
-
-
0034702841
-
Structural analysis of the human pro-apoptotic gene Bik: Chromosomal localization, genomic organization and localization of promoter sequences
-
Verma S, Budarf ML, Emanuel BS, Chinnadurai G. Structural analysis of the human pro-apoptotic gene Bik: chromosomal localization, genomic organization and localization of promoter sequences. Gene 2000; 254: 157-162.
-
(2000)
Gene
, vol.254
, pp. 157-162
-
-
Verma, S.1
Budarf, M.L.2
Emanuel, B.S.3
Chinnadurai, G.4
-
19
-
-
0034178250
-
Human Kruppel-like factor 8: A CACCC-box binding protein that associates with CtBP and represses transcription
-
van Vliet J, Turner J, Crossley M. Human Kruppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription. Nucleic Acids Res 2000; 28: 1955-1962.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 1955-1962
-
-
Van Vliet, J.1
Turner, J.2
Crossley, M.3
-
20
-
-
33745172454
-
Redox sensor CtBP mediates hypoxia-induced tumor cell migration
-
Zhang Q, Wang SY, Nottke AC, Rocheleau JV, Piston DW, Goodman RH. Redox sensor CtBP mediates hypoxia-induced tumor cell migration. Proc Natl Acad Sci USA 2006; 103: 9029-9033.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9029-9033
-
-
Zhang, Q.1
Wang, S.Y.2
Nottke, A.C.3
Rocheleau, J.V.4
Piston, D.W.5
Goodman, R.H.6
-
21
-
-
0035553918
-
The pro-apoptotic protein, Bik, exhibits potent antitumor activity that is dependent on its BH3 domain
-
Tong Y, Yang Q, Vater C, Venkatesh LK, Custeau D, Chittenden T et al. The pro-apoptotic protein, Bik, exhibits potent antitumor activity that is dependent on its BH3 domain. Mol Cancer Ther 2001; 1: 95-102.
-
(2001)
Mol Cancer Ther
, vol.1
, pp. 95-102
-
-
Tong, Y.1
Yang, Q.2
Vater, C.3
Venkatesh, L.K.4
Custeau, D.5
Chittenden, T.6
-
22
-
-
27744535981
-
Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik
-
Oppermann M, Geilen CC, Fecker LF, Gillissen B, Daniel PT, Eberle J. Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik. Oncogene 2005; 24: 7369-7380.
-
(2005)
Oncogene
, vol.24
, pp. 7369-7380
-
-
Oppermann, M.1
Geilen, C.C.2
Fecker, L.F.3
Gillissen, B.4
Daniel, P.T.5
Eberle, J.6
-
23
-
-
0029790857
-
Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19 K
-
Han J, Sabbatini P, White E. Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19 K. Mol Cell Biol 1996; 16: 5857-5864.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5857-5864
-
-
Han, J.1
Sabbatini, P.2
White, E.3
-
24
-
-
0033179162
-
Expression of the death gene Bik/Nbk promotes sensitivity to drug-induced apoptosis in corticosteroid-resistant T-cell lymphoma and prevents tumor growth in severe combined immunodeficient mice
-
Daniel PT, Pun KT, Ritschel S, Sturm I, Holler J, Dorken B et al. Expression of the death gene Bik/Nbk promotes sensitivity to drug-induced apoptosis in corticosteroid-resistant T-cell lymphoma and prevents tumor growth in severe combined immunodeficient mice. Blood 1999; 94: 1100-1107.
-
(1999)
Blood
, vol.94
, pp. 1100-1107
-
-
Daniel, P.T.1
Pun, K.T.2
Ritschel, S.3
Sturm, I.4
Holler, J.5
Dorken, B.6
-
25
-
-
0032835528
-
Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer
-
Castells A, Ino Y, Louis DN, Ramesh V, Gusella JF, Rustgi AK. Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer. Gastroenterology 1999; 117: 831-837.
-
(1999)
Gastroenterology
, vol.117
, pp. 831-837
-
-
Castells, A.1
Ino, Y.2
Louis, D.N.3
Ramesh, V.4
Gusella, J.F.5
Rustgi, A.K.6
-
26
-
-
33644954099
-
Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma
-
Sturm I, Stephan C, Gillissen B, Siebert R, Janz M, Radetzki S et al. Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma. Cell Death Differ 2006; 13: 619-627.
-
(2006)
Cell Death Differ
, vol.13
, pp. 619-627
-
-
Sturm, I.1
Stephan, C.2
Gillissen, B.3
Siebert, R.4
Janz, M.5
Radetzki, S.6
-
27
-
-
0842347424
-
Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death
-
Coultas L, Bouillet P, Stanley EG, Brodnicki TC, Adams JM, Strasser A. Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death. Mol Cell Biol 2004; 24: 1570-1581.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1570-1581
-
-
Coultas, L.1
Bouillet, P.2
Stanley, E.G.3
Brodnicki, T.C.4
Adams, J.M.5
Strasser, A.6
-
28
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2002; 2: 183-192.
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
29
-
-
67349187962
-
PAR bZIP-bik is a novel transcriptional pathway that mediates oxidative stress-induced apoptosis in fibroblasts
-
Ritchie A, Gutierrez O, Fernandez-Luna JL. PAR bZIP-bik is a novel transcriptional pathway that mediates oxidative stress-induced apoptosis in fibroblasts. Cell Death Differ 2009.
-
(2009)
Cell Death Differ
-
-
Ritchie, A.1
Gutierrez, O.2
Fernandez-Luna, J.L.3
-
30
-
-
34247254266
-
NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition
-
Shimazu T, Degenhardt K, Nur EKA, Zhang J, Yoshida T, Zhang Y et al. NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition. Genes Dev 2007; 21: 929-941.
-
(2007)
Genes Dev
, vol.21
, pp. 929-941
-
-
Shimazu, T.1
Degenhardt, K.2
Nur, E.K.A.3
Zhang, J.4
Yoshida, T.5
Zhang, Y.6
-
31
-
-
21244462014
-
BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death
-
Mathai JP, Germain M, Shore GC. BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem 2005; 280: 23829-23836.
-
(2005)
J Biol Chem
, vol.280
, pp. 23829-23836
-
-
Mathai, J.P.1
Germain, M.2
Shore, G.C.3
-
32
-
-
33750308598
-
Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression
-
Quinlan KG, Verger A, Kwok A, Lee SH, Perdomo J, Nardini M et al. Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression. Mol Cell Biol 2006; 26: 8202-8213.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8202-8213
-
-
Quinlan, K.G.1
Verger, A.2
Kwok, A.3
Lee, S.H.4
Perdomo, J.5
Nardini, M.6
-
33
-
-
0032167456
-
Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators
-
Turner J, Crossley M. Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators. EMBO J 1998; 17: 5129-5140.
-
(1998)
EMBO J
, vol.17
, pp. 5129-5140
-
-
Turner, J.1
Crossley, M.2
-
34
-
-
0034532675
-
The biology of the mammalian Kruppel-like family of transcription factors
-
Dang DT, Pevsner J, Yang VW. The biology of the mammalian Kruppel-like family of transcription factors. Int J Biochem Cell Biol 2000; 32: 1103-1121.
-
(2000)
Int J Biochem Cell Biol
, vol.32
, pp. 1103-1121
-
-
Dang, D.T.1
Pevsner, J.2
Yang, V.W.3
-
35
-
-
35148830743
-
The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor
-
Paliwal S, Kovi RC, Nath B, Chen YW, Lewis BC, Grossman SR. The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor. Cancer Res 2007; 67: 9322-9329.
-
(2007)
Cancer Res
, vol.67
, pp. 9322-9329
-
-
Paliwal, S.1
Kovi, R.C.2
Nath, B.3
Chen, Y.W.4
Lewis, B.C.5
Grossman, S.R.6
-
36
-
-
39049124311
-
Lewis BC. p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein
-
Chen YW, Paliwal S, Draheim K, Grossman SR, Lewis BC. p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein. Cancer Res 2008; 68: 476-482.
-
(2008)
Cancer Res
, vol.68
, pp. 476-482
-
-
Chen, Y.W.1
Paliwal, S.2
Draheim, K.3
Grossman, S.R.4
-
37
-
-
0141716853
-
Cancer: Cues for migration
-
Bernards R. Cancer: cues for migration. Nature 2003; 425: 247-248.
-
(2003)
Nature
, vol.425
, pp. 247-248
-
-
Bernards, R.1
-
38
-
-
19344364856
-
Kemp CJ. p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and-independent pathways
-
Kelly-Spratt KS, Gurley KE, Yasui Y, Kemp CJ. p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and-independent pathways. PLoS Biol 2004; 2: E242.
-
(2004)
PLoS Biol
, vol.2
-
-
Kelly-Spratt, K.S.1
Gurley, K.E.2
Yasui, Y.3
-
39
-
-
33847261047
-
Modeling INK4/ARF tumor suppression in the mouse
-
Berger JH, Bardeesy N. Modeling INK4/ARF tumor suppression in the mouse. Curr Mol Med 2007; 7: 63-75.
-
(2007)
Curr Mol Med
, vol.7
, pp. 63-75
-
-
Berger, J.H.1
Bardeesy, N.2
-
40
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998; 282: 1497-1501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
|